Research Group on the Study of Cardiometabolic and Renal Risk

Cardiovascular Area

To start-up the laboratory for the analysis of podocytes (identification, cultivation and phenotyping) and its derivatives: micro-RNA, exosomes

To identify a circulating and exosomal non-coding RNA – mRNA interaction networks associated to renal damage progression

The integration of metabolomics and genomics in the study of factors related to the development of kidney damage

Development of studies for noninvasive hemodynamic characterization in vascular pathology

Analysis of morbidity and mortality linked to the presence of hypertension and renal injury

Development of in vitro studies of platelet and leukocyte adhesion in venous thromboembolism

Genetic studies related to obesity and overweight and venous thromboembolism

Development of phase III and IV clinical trials

Characterize the cardiovascular risk and alterations in renal function in patients with HIV infection and in HIV/HBV-HCV co-infected

Assess the comorbidities of patients with HIV and their impact on the development of frailty and quality of life

Assess the risk of impaired kidney function in people on PrEP

Determine the cardiovascular risk and alterations in renal function in patients with HIV infection

Analyze the comorbidities of patients with HIV infection and their impact on the development of frailty and quality of life

Characterize the natural history of viral hepatitis: study of factors related to the development of cardiometabolic damage and development of clinical events

Develop biomarkers to diagnose and predict the development of clinical events in patients with HIV infection, viral hepatitis and other infectious pathologies

Assess the risk of impaired renal function in people on PrEP and its management

Develop interventions for primary and secondary prevention in this context: microelimination strategies, early diagnosis and personalized patient management

Dr. Josep Redón i Mas
Coordinator
Dr. Josep Redón i Mas
josep.redon@uv.es; jredon@uv.es

Dr. Josep Redón i Mas
Coordinator
Dra. Raquel Cortés Vergaz
raquel.cortes@uv.es

RESEARCHERS
Leading, R4

Josep Redón i Mas    

Established, R3

Raquel Cortés Vergaz    
Mª José Galindo Puerto
Mª José Forner Giner
Fernando Martínez García

Recognised/Emerging, R2

Elena Furió Rodríguez
David Martí Aguado

Ana Ortega Gutiérrez

Adrián Ruiz Hernández
Anaïs Corma Gómez

First Stage, R1

Olga Martínez Arroyo
Celia Prades Sirvent
Ana Flores Chova

STAFF
Collaborating Researchers

Javier Díaz Carnicero
Elena Solaz Moreno

Nurse
Technicians

Noemí Dolz Gilba
Marta Méndez Debaets
Inmaculada Saurí Ferrer

Administrative assistant

Iván Colmena Martínez

Publications
Impact of low alcohol consumption in the natural history of cirrhosis. Marti-Aguado D, Vilar-Gomez E. Hepatobiliary Surgery and Nutrition. 2024 Feb 1;13(1):161-164. doi: 10.21037/hbsn-23-615. PMID: 38322204

MASLD biomarkers: are we facing a new era?. Maya-Miles D, Ampuero J, Marti-Aguado D, Conthe A, Gallego-Duran R. Gastroenterologia y Hepatologia. 2024 Feb 12:S0210-5705(24)00053-0. doi: 10.1016/j.gastrohep.2024.02.004. PMID: 38355096

Perspectives of people with HIV and HIV clinicians on characteristics of antiretroviral treatment and HIV-related symptoms. Puerto M, Puig J, Pérez-Molina J, de Apodaca M. HIV Medicine. 2024 Jan 12. doi: 10.1111/hiv.13609. PMID: 38214438

Real-life data of immune recovery using bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed people living with HIV. Results at 48-96 weeks of RETROBIC Study. Troya J, Pousada G, Micán R, Galera C, Sanz J, de Los Santos I, Dueñas C, Cabello N, Martín C, Galindo MJ, Garcinuño MÁ, Pedrero-Tomé R, Buzón L. Journal of Antimicrobial Chemotherapy. 2024 Jan 24:dkae011. doi: 10.1093/jac/dkae011. PMID: 38267266

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Endorsed by the European Renal Association (ERA) and the International Society of Hypertension (ISH). Mancia Chairperson G, Kreutz Co-Chair R, Brunstrom M, Burnier M, Grassi G, Januszewicz A, Muiesan M, Tsioufis K, Agabiti-Rosei E, Algharably E, Azizi M, Benetos A, Borghi C, Hitij J, Cifkova R, Coca A, Cornelissen V, Cruickshank K, Cunha P, Danser A, de Pinho R, Delles C, Dominiczak A, Dorobantu M, Doumas M, Fernandez-Alfonso M, Halimi J, Jarai Z, Jelakovic B, Jordan J, Kuznetsova T, Laurent S, Lovic D, Lurbe E, Mahfoud F, Manolis A, Miglinas M, Narkiewicz K, Niiranen T, Palatini P, Parati G, Pathak A, Persu A, Polonia J, Redon J, Sarafidis P, Schmieder R, Spronck B, Stabouli S, Stergiou G, Taddei S, Thomopoulos C, Tomaszewski M, Van de Borne P, Wanner C, Weber T, Williams B, Zhang Z, Kjeldsen S. Journal of Hypertension. 2023 Dec 1;41(12):1874-2071. doi: 10.1097/HJH.0000000000003480. PMID: 37345492

Acquired aggressive multisystemic disseminated lobular capillary haemangioma: a life threatening disorder. Monteagudo C, Porcar-Saura S, Navarro S, Burgues O, Gonzalez J, Ferrandez A, Forner M. Pathology. 2023 Aug;55(5):729-732. doi: 10.1016/j.pathol.2022.11.014. PMID: 36894353

All-cause hospitalisation among people living with HIV according to gender, mode of HIV acquisition, ethnicity, and geographical origin in Europe and North America: findings from the ART-CC cohort collaboration. Rein S, Lampe F, Ingle S, Sterne J, Trickey A, Gill M, Papastamopoulos V, Wittkop L, van der Valk M, Kitchen M, Guest J, Satre D, Wandeler G, Galindo P, Castilho J, Crane H, Smith C. Lancet. Public Health. 2023 Oct;8(10):e776-e787. doi: 10.1016/S2468-2667(23)00178-0. PMID: 37777287

Association of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: the national health and nutrition examination survey 1999-2018. Gonzalez-Martin R, Grau-Perez M, Sebastian-Leon P, Diaz-Gimeno P, Vidal C, Tellez-Plaza M, Dominguez F. Environmental Research. 2023 Sep 15:233:116514. doi: 10.1016/j.envres.2023.116514. PMID: 37392826

Association of single and joint metals with albuminuria and estimated glomerular filtration longitudinal change in middle-aged adults from Spain: The Aragon workers health study. Grau-Perez M, Domingo-Relloso A, Garcia-Barrera T, Gomez-Ariza J, Leon-Latre M, Casasnovas J, Moreno-Franco B, Laclaustra M, Guallar E, Navas-Acien A, Pastor-Barriuso R, Redon J, Tellez-Plaza M. Environmental Pollution. 2023 Feb 1;318:120851. doi: 10.1016/j.envpol.2022.120851. PMID: 36509352

Bariatric surgery is associated with alcohol-related liver disease and psychiatric disorders associated with AUD. Alvarado-Tapias E, Marti-Aguado D, Kennedy K, Fernandez-Carrillo C, Ventura-Cots M, Morales-Arraez D, Atkinson S, Clemente-Sanchez A, Argemi J, Bataller R. Obesity Surgery. 2023 May;33(5):1494-1505. doi: 10.1007/s11695-023-06490-w. PMID: 36881347

Biological treatment interruption in Inflammatory Bowel Disease: motivation and predictive factors. González MRD, Ballester MP, Romero-González E, Sánchez-Pardo AM, Marti-Aguado D, Tosca J, Suria C, Ausejo RA, Moreno IP, Silvestre MDP, Pérez MM, Bosca-Watts MM. Gastroenterologia y Hepatologia. 2023 Nov;46(9):671-681. doi: 10.1016/j.gastrohep.2022.10.021. PMID: 36375696

Cardiovascular risk of metabolically healthy obesity in two european populations: prevention potential from a metabolomic study. Wei D, Gonzalez-Marrachelli V, Melgarejo J, Liao C, Hu A, Janssens S, Verhamme P, Van Aelst L, Vanassche T, Redon J, Tellez-Plaza M, Martin-Escudero J, Monleon D, Zhang Z. Cardiovascular Diabetology. 2023 Apr 7;22(1):82. doi: 10.1186/s12933-023-01815-6. PMID: 37029406

Comparison of GLP-1 Receptor agonists and other glucose-lowering agents on cardiovascular outcomes in individuals with type 2 diabetes and obesity: a spanish real-world population-based study. Palanca A, Javier Ampudia-Blasco F, Miguel Calderon J, Sauri I, Martinez-Hervas S, Luis Trillo J, Redon J, Real J. Diabetes Research and Clinical Practice. 2023 Dec 22:111071. doi: 10.1016/j.diabres.2023.111071. PMID: 38142748

Corrigendum to Genetic interaction in the association between oxidative stress and diabetes in the Spanish population [Free Radic. Biol. Med. 205 (2023) 62-68]. Melero R, Quiroz-Rodríguez ME, Lara-Hernández F, Redón J, Sáez G, Briongos-Figuero LS, Abadía-Otero J, Martín-Escudero JC, Chaves FJ, Ayala G, García-García AB. Free Radical Biology & Medicine. 2023 Jul 22;207:181-182. doi: 10.1016/j.freeradbiomed.2023.07.017. PMID: 37487450

Current dilemmas in Hepatitis Virus C management. What should we do after achieving sustained virologic response?. Conthe A, Ahumada A, Durán RG, Marti-Aguado D, Ibáñez-Samaniego L. Gastroenterologia y Hepatología. 2023 Oct 7:S0210-5705(23)00434-X. doi: 10.1016/j.gastrohep.2023.10.001. PMID: 37813183

Development and validation of an image biomarker to identify metabolic dysfunction associated steatohepatitis: MR-MASH score. Marti-Aguado D, Arnouk J, Liang J, Lara-Romero C, Behari J, Furlan A, Jimenez-Pastor A, Ten-Esteve A, Alfaro-Cervello C, Bauza M, Gallen-Peris A, Gimeno-Torres M, Merino-Murgui V, Perez-Girbes A, Benlloch S, Perez-Rojas J, Puglia V, Ferrández-Izquierdo A, Aguilera V, Giesteira B, França M, Monton C, Escudero-García D, Alberich-Bayarri A, Serra M, Bataller R, Romero-Gomez M, Marti-Bonmati L. Liver International. 2023 Oct 30. doi: 10.1111/liv.15766. PMID: 37904633

Diminishing benefits of urban living for children and adolescents’ growth and development. NCD Risk Factor Collaboration (NCD-RisC). Nature. 2023 Mar;615(7954):874-883. doi: 10.1038/s41586-023-05772-8. PMID: 36991188

Dysimmunity in common variable immunodeficiency is associated with alterations in oral, respiratory, and intestinal microbiota. Cabanero-Navalon M, Garcia-Bustos V, Mira A, Moral P, Salavert-Lleti M, Ginet M, Beltrán M, Parra J, Bracke C, Carda-Diéguez M. Clinical Immunology. 2023 Nov:256:109796. doi: 10.1016/j.clim.2023.109796. PMID: 37774905

Effectiveness and tolerability of dolutegravir/lamivudine for the treatment of HIV-1 infection in clinical practice. Suárez-García I, Alejos B, Hernando V, Viñuela L, Vera García M, Rial-Crestelo D, Pérez Elías MJ, Albendín Iglesias H, Peraire J, Tiraboschi J, Díaz A, Moreno S, Jarrín I; Cohort of the Spanish HIV/AIDS Research Network (CoRIS). Journal of Antimicrobial Chemotherapy. 2023 Jun 1;78(6):1423-1432. doi: 10.1093/jac/dkad102. PMID: 37099559

Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV. Brañas F, Torralba M, Antela A, Vergas J, Ramírez M, Ryan P, Dronda F, Galindo MJ, Machuca I, Bustinduy MJ, Cabello A, Montes ML, Sánchez-Conde M; FUNCFRAIL study group. BMC Geriatrics. 2023 Jan 3;23(1):4. doi: 10.1186/s12877-022-03719-8. PMID: 36597036

Efficacy and safety of dolutegravir/rilpivirine in real-world clinical practice. GeSIDA study 1119. Palacios R, Gómez-Ayerbe C, Casado JL, Tejerina F, Montes ML, Castaño M, Ocampo A, Rial D, Ribera E, Galindo MJ, Hidalgo C, Fariñas C, Montero M, Payeras T, Fanjul F, de la Torre J, Santos J. HIV Medicine. 2023 Aug;24(8):933-937. doi: 10.1111/hiv.13489. PMID: 37016556

Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratio in predicting non-AIDS events. Martínez-Sanz J, Díaz-Álvarez J, Rosas M, Ron R, Iribarren JA, Bernal E, Gutiérrez F, Ruiz Sancho A, Cabello N, Olalla J, Moreno S, Serrano-Villar S; CoRIS. EBioMedicine. 2023 Sep;95:104773. doi: 10.1016/j.ebiom.2023.104773. PMID: 37639938

Genetic interaction in the association between oxidative stress and diabetes in the Spanish population. Melero R, Quiroz-Rodriguez M, Lara-Hernandez F, Redon J, Saez G, Briongos-Figuero L, Abadia-Otero J, Martin-Escudero J, Chaves F, Ayala G, Garcia-Garcia A. Free Radical Biology & Medicine. 2023 Jun 1;205:62-68. doi: 10.1016/j.freeradbiomed.2023.05.030. PMID: 37268047

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c. NCD Risk Factor Collaboration (NCD-RisC). Nature Medicine. 2023 Nov;29(11):2885-2901. doi: 10.1038/s41591-023-02610-2. PMID: 37946056

High miR-126-3p levels associated with cardiovascular events in a general population. Martinez-Arroyo O, Ortega A, Flores-Chova A, Sanchez-Garcia B, Garcia-Garcia A, Chaves F, Martin-Escudero J, Forner M, Redon J, Cortes R. European Journal of Internal Medicine. 2023 Jul;113:49-56. doi: 10.1016/j.ejim.2023.04.013. PMID: 37080818

Impact of finerenone-induced albuminuria reduction on chronic kidney disease outcomes in type 2 Diabetes A mediation analysis. Agarwal R, Tu W, Farjat A, Fang Y, Toto R, Kaul S, Lawatscheck R, Rohwedder K, Ruilope L, Rossing P, Pitt B, Filippatos G, Anker S, Bakris G. Annals of Internal Medicine. 2023 Dec;176(12):1606-1616. doi: 10.7326/M23-1023. PMID: 38048573

Improving recognition of fracture risk in people with human immunodeficiency virus: performance and model contribution of two common risk assessment tolos. Vizcarra P, Moreno A, Vivancos MJ, Muriel Garcia A, Pelazas Gonzalez R, Gutierrez F, Corona Mata D, Galindo P, Calzado S, Casado JL. AIDS Patient Care and STDS. 2023 Jan;37(1):11-21. doi: 10.1089/apc.2022.0183. PMID: 36576916

Metabolomic patterns, redox-related genes and metals, and bone fragility endpoints in the Hortega Study. Galvez-Fernandez M, Rodriguez-Hernandez Z, Grau-Perez M, Chaves F, Garcia-Garcia A, Amigo N, Monleon D, Garcia-Barrera T, Gomez-Ariza J, Briongos-Figuero L, Perez-Castrillon J, Redon J, Tellez-Plaza M, Martin-Escudero J. Free Radical Biology & Medicine. 2023 Jan;194:52-61. doi: 10.1016/j.freeradbiomed.2022.11.007. PMID: 36370960

Pancreatic steatosis and iron overload increases cardiovascular risk in non-alcoholic fatty liver disease. Marti-Aguado D, Ten-Esteve A, Baracaldo-Silva C, Crespo A, Coello E, Merino-Murgui V, Fernandez-Paton M, Alfaro-Cervello C, Sanchez-Martin A, Bauza M, Jimenez-Pastor A, Perez-Girbes A, Benlloch S, Perez-Rojas J, Puglia V, Ferrandez A, Aguilera V, Latorre M, Monton C, Escudero-Garcia D, Bosch-Roig I, Alberich-Bayarri A, Marti-Bonmati L. Frontiers in Endocrinology. 2023 Aug 3;14:1213441. doi: 10.3389/fendo.2023.1213441. PMID: 37600695

Persistence and determinants of blood pressure phenotypes according to office and ambulatory blood pressure measurements in youth. Martinez F, Redon J, Aguilar F, Calderon JM, Lurbe E. Hypertension Research. 2023 May;46(5):1257-1266. doi: 10.1038/s41440-022-01159-w. PMID: 36635525

Plasma exosomal non-coding RNA profile associated with renal damage reveals potential therapeutic targets in lupus nephritis. Flores-Chova A, Martinez-Arroyo O, Riffo-Campos A, Ortega A, Forner M, Cortes R. International Journal of Molecular Sciences. 2023 Apr 11;24(8):7088. doi: 10.3390/ijms24087088. PMID: 37108249

Psychometric properties of the Clarke questionnaire for hypoglycemia awareness in the Spanish population with type 2 diabetes. Orozco-Beltran D, Lecumberri-Pascual E, Quesada J, Moreno-Perez O, Ruiz-Quintero M, Pomares-Gomez F, Jodar-Gimeno E, Pardo-Ruiz C, Mascarell-Martinez I, Mirete-Lopez R, Morant-Bes B, Borrachero-Guijarro J, Zapatero-Larrauri M, Aparicio-Egea M, Paniagua-Merchan C, Requena-Ferrer R, Caride-Miana E, Fernandez-Gimenez A, Lopez-Pineda A, Nouni-Garcia R, Carratala-Munuera C, Cebrian-Cuenca A. Postgraduate Medicine. 2023 Mar;135(2):141-148. doi: 10.1080/00325481.2022.2138469. PMID: 36475508

Rab3A/Rab27A system silencing ameliorates high glucose-induced injury in podocytes. Martinez-Arroyo O, Flores-Chova A, Sanchez-Garcia B, Redon J, Cortes R, Ortega A. Biology-Basel. 2023 May 9;12(5):690. doi: 10.3390/biology12050690. PMID: 37237503

Real-world evaluation of GLP-1 receptor agonist therapy persistence, adherence and therapeutic inertia among obese adults with Type 2 Diabetes. Palanca A, Ampudia Blasco F, Calderon J, Sauri I, Martinez Hervas S, Trillo J, Redon J, Real J. Diabetes Therapy. 2023 Apr;14(4):723-736. doi: 10.1007/s13300-023-01382-9. PMID: 36847952

Safety and immunogenicity of the protein-based PHH-1V compared to BNT162b2 as a heterologous SARS-CoV-2 booster vaccine in adults vaccinated against COVID-19: a multicentre, randomised, double-blind, non-inferiority phase IIb trial. Corominas J, Garriga C, Prenafeta A, Moros A, Canete M, Barreiro A, Gonzalez-Gonzalez L, Madrenas L, Guell I, Clotet B, Izquierdo-Useros N, Raich-Regue D, Gallemi M, Blanco J, Pradenas E, Trinite B, Prado J, Blanch-Lombarte O, Perez-Caballero R, Plana M, Esteban I, Pastor-Quinones C, Nunez-Costa X, Taleb R, McSkimming P, Soriano A, Nava J, Anagua J, Ramos R, Lluch R, Comes A, Romero S, Gomez X, Sans-Pola C, Molto J, Benet S, Bailon L, Arribas J, Borobia A, Parada J, Navarro-Perez J, Forner Giner M, Lucas R, Jimenez M, Compan S, Alvarez-Mon M, Troncoso D, Arana-Arri E, Meijide S, Imaz-Ayo N, Garcia P, de la Villa Martinez S, Fernandez S, Prat T, Torroella E, Ferrer L. Lancet Regional Health. Europe. 2023 May;28:100613. doi: 10.1016/j.lanepe.2023.100613. PMID: 37131861

Single-Pill combination with three antihypertensive agents to improve blood pressure control in hypertension: focus on olmesartan-based combinations. Burnier M, Redon J, Volpe M. High Blood Pressure & Cardiovascular Prevention. 2023 Mar;30(2):109-121. doi: 10.1007/s40292-023-00563-8. PMID: 36696054

Subclinical versus advanced forms of alcohol-related liver disease: need for early detection. Gomez-Medina C, Melo L, Marti-Aguado D, Bataller R. Clinical and Molecular Hepatology. 2023 Jan;29(1):1-15. doi: 10.3350/cmh.2022.0017. PMID: 35430784

Towards a personalized health care using a divisive hierarchical clustering approach for comorbidity and the prediction of conditioned group risks. Navarro-Cerdán J, Sánchez-Gomis M, Pons P, Gálvez-Settier S, Valverde F, Ferrer-Albero A, Saurí I, Fernández A, Redon J. Health Informatics Journal. 2023 Oct-Dec;29(4):14604582231212494. doi: 10.1177/14604582231212494. PMID: 38072502

Traffic density exposure, oxidative stress biomarkers and plasma metabolomics in a population-based sample: the Hortega Study. Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero J, Ramis R. Antioxidants. 2023 Dec 15;12(12):2122. doi: 10.3390/antiox12122122. PMID: 38136241

Weight gain in HIV-infected patients. Rodríguez AP, Lillo IS, González CS, Galindo MJ. AIDS Reviews. 2023;25(1):14-26. doi: 10.24875/AIDSRev.M22000057. PMID: 36952657

2022 Practice guidelines for the management of arterial hypertension of the Spanish Society of Hypertension. Gorostidi M, Gijón-Conde T, de la Sierra A, Rodilla E, Rubio E, Vinyoles E, Oliveras A, Santamaría R, Segura J, Molinero A, Pérez-Manchón D, Abad M, Abellán J, Armario P, Banegas JR, Camafort M, Catalina C, Coca A, Divisón JA, Domenech M, Martell N, Martín-Rioboó E, Morales-Olivas F, Pallarés V, Pérez de Isla L, Prieto MA, Redón J, Ruilope LM, García-Donaire JA. Hipertensión y Riesgo Vascular. 2022 Oct-Dec;39(4):174-194. doi: 10.1016/j.hipert.2022.09.002. PMID: 36153303

A comprehensive urban programme to reduce energy poverty and its effects on health and wellbeing of citizens in six European countries: study protocol of a controlled trial. Stevens M, Raat H, Ferrando M, Vallina B, Lucas R, Middlemiss L, Redon J, Rocher E, van Grieken A. BMC Public Health. 2022 Aug 19;22(1):1578. doi: 10.1186/s12889-022-13968-2. PMID: 35986259

Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. Henkens M, Raafs A, Verdonschot J, Linschoten M, van Smeden M, Wang P, van der Hooft B, Tieleman R, Janssen M, ter Bekke R, Hazebroek M, van der Horst I, Asselbergs F, Magdelijns F, Heymans S. BMC Geriatrics. 2022 Mar 5;22(1):184. doi: 10.1186/s12877-021-02673-1. PMID: 35247983

Angiotensin receptor blockers evaluated by office and home blood pressure measurements. TeleHBPM Study. Barroso Weimar Kunz Sebba, Brandao AA, Valverde de Oliveira Vitorino P, Diogenes de Magalhaes Feitosa A, Costa Duarte Barbosa E, Dischinger Miranda R, Redon J, Camafort-Babkowski M, Coca A, Mota Gomes MA. Arquivos Brasileiros de Cardiologia. 2022 May 9;118(6):1069-1082. doi: 10.36660/abc.20210504. PMID: 35544853

Association between exercise frequency with renal and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk. Bohm M, Schumacher H, Werner C, Teo K, Lonn E, Mahfoud F, Speer T, Mancia G, Redon J, Schmieder R, Sliwa K, Marx N, Weber M, Laufs U, Williams B, Yusuf S, Mann J. Cardiovascular Diabetology. 2022 Jan 20;21(1):12. doi: 10.1186/s12933-021-01429-w. PMID: 35057807

Automated whole-liver MRI segmentation to assess steatosis and iron quantification in chronic liver disease. Marti-Aguado D, Jimenez-Pastor A, Alberich-Bayarri A, Rodriguez-Ortega A, Alfaro-Cervello C, Mestre-Alagarda C, Bauza M, Gallen-Peris A, Valero-Perez E, Ballester MP, Gimeno-Torres M, Perez-Girbes A, Benlloch S, Perez-Rojas J, Puglia V, Ferrandez A, Aguilera V, Escudero-Garcia D, Serra MA, Marti-Bonmati L. Radiology. 2022 Feb;302(2):345-354. doi: 10.1148/radiol.2021211027. PMID: 34783592

Biofluid specificity of long non-coding RNA profile in hypertension: relevance of exosomal fraction. Riffo-Campos AL, Perez-Hernandez J, Martinez-Arroyo O, Ortega A, Flores-Chova A, Redon J, Cortes R. International Journal of Molecular Sciences. 2022 May 6;23(9):5199. doi: 10.3390/ijms23095199. PMID: 35563588

Cigarette smoking and liver diseases. Marti-Aguado D, Clemente-Sanchez A, Bataller R. Journal of Hepatology. 2022 Jul;77(1):191-205. doi: 10.1016/j.jhep.2022.01.016. PMID: 35131406

Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. Linschoten M, Uijl A, Schut A, et al. European Heart Journal. 2022 Mar 14;43(11):1104-1120. doi: 10.1093/eurheartj/ehab656. PMID: 34734634

Current clinical spectrum of common variable immunodeficiency in Spain: The multicentric nationwide GTEM-SEMI-CVID registry. Cabanero-Navalon M, Garcia-Bustos V, Nunez-Beltran M, Fernandez P, Mateu L, Solanich X, Carrillo-Linares J, Robles-Marhuenda A, Puchades-Gimeno F, Ballesta A, Lopez-Osle N, Torralba-Cabeza M, Masdeu A, Gil J, Gaya N, Castellanos G, Sanchez-Martinez R, Barragan-Casas J, Gonzalez-Garcia A, de la Pena J, Lopez-Wolf D, Rufete A, Mora A, Giner M, Moral P. Frontiers in Immunology. 2022 Oct 28;13:1033666. doi: 10.3389/fimmu.2022.1033666. PMID: 36389743

Different profiles among older adults with HIV according to their chronological age and the year of HIV diagnosis: The FUNCFRAIL cohort study (GeSIDA 9817). Brañas F, Galindo MJ, Torralba M, Antela A, Vergas J, Ramírez M, Ryan P, Dronda F, Busca C, Machuca I, Bustinduy MJ, Cabello A, Sánchez-Conde M; FUNCFRAIL study group. PLoS One. 2022 Mar 30;17(3):e0266191. doi: 10.1371/journal.pone.0266191. PMID: 35353855

Discovering HIV related information by means of association rules and machine learning. Araujo L, Martinez-Romo J, Bisbal O, Sanchez-de-Madariaga R; Cohort of the National AIDS Network (CoRIS). Scientific Reports. 2022 Oct 28;12(1):18208. doi: 10.1038/s41598-022-22695-y. PMID: 36307506

Dolutegravir plus rilpivirine: benefits beyond viral suppression: DORIPEX retrospective study. Troya J, Duenas C, Irazola I, de Los Santos I, de la Fuente S, Gil D, Hernandez C, Galindo M, Gomez J, Delgado E, Moreno-Garcia E, Posada G, Aldamiz T, Iribarren J, Guerra J, Moran M, Galera C, Fuente J, Pelaez A, Cervero M, Garcinuno M, Montero M, Ceballos F, Buzon L. Medicine. 2022 Jun 17;101(24):e29252. doi: 10.1097/MD.0000000000029252. PMID: 35713430

Down-regulation of the longevity-associated protein SIRT1 in peripheral blood mononuclear cells of treated HIV patients. Gruevska A, Moragrega A, Galindo M, Esplugues J, Blas-Garcia A, Apostolova N. Cells. 2022 Jan 20;11(3):348. doi: 10.3390/cells11030348. PMID: 35159154

Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial. Schlaich MP, Bellet M, Weber MA, Danaietash P, Bakris GL, Flack JM, Dreier RF, Sassi-Sayadi M, Haskell LP, Narkiewicz K, Wang JG. Lancet. 2022 Dec 3;400(10367):1927-1937. doi: 10.1016/S0140-6736(22)02034-7. PMID: 36356632

Environmental-level exposure to metals and metal-mixtures associated with spirometry-defined lung disease in American Indian adults: Evidence from the Strong Heart Study. Sobel M, Navas-Acien A, Powers M, Grau-Perez M, Goessler W, Best LG, Umans J, Oelsner EC, Podalanczuk A, Sanchez TR. Environmental Research. 2022 May 1;207:112194. doi: 10.1016/j.envres.2021.112194. PMID: 34653410

Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019. Fanciulli C, Berenguer J, Busca C, Vivancos MJ, Tellez MJ, Dominguez L, Domingo P, Navarro J, Santos J, Iribarren JA, Morano L, Artero A, Moreno J, Rivero-Roman A, Santos I, Giner L, Arminanzas C, Montero M, Manzardo C, Cifuentes C, Garcia C, Galindo MJ, Ferrero OL, Sanz J, de la Fuente B, Rodriguez C, Gaspar G, Perez L, Losa JE, Force L, Veloso S, Martinez-Alfaro E, Jarrin I, De Miguel M, Gonzalez Garcia J. HIV Medicine. 2022 Aug;23(7):705-716. doi: 10.1111/hiv.13229. PMID: 35037379

Exosomal and plasma non-coding RNA signature associated with urinary albumin excretion in hypertension. Riffo-Campos A, Perez-Hernandez J, Ortega A, Martinez-Arroyo O, Flores-Chova A, Redon J, Cortes R. International Journal of Molecular Sciences. 2022 Jan 13;23(2):823. doi: 10.3390/ijms23020823. PMID: 35055008

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: the Hortega Study. Galvez-Fernandez M, Sanchez-Saez F, Domingo-Relloso A, Rodriguez-Hernandez Z, Tarazona S, Gonzalez-Marrachelli V, Grau-Perez M, Morales-Tatay J, Amigo N, Garcia-Barrera T, Gomez-Ariza J, Chaves F, Garcia-Garcia A, Melero R, Tellez-Plaza M, Martin-Escudero J, Redon J, Monleon D. Redox Biology. 2022 Jun;52:102314. doi: 10.1016/j.redox.2022.102314. PMID: 35460952

Healthy lifestyle, metabolomics and incident type 2 diabetes in a population-based cohort from Spain. Delgado-Velandia M, Gonzalez-Marrachelli V, Domingo-Relloso A, Galvez-Fernandez M, Grau-Perez M, Olmedo P, Galan I, Rodriguez-Artalejo F, Amigo N, Briongos-Figuero L, Redon J, Martin-Escudero J, Monleon-Salvado D, Tellez-Plaza M, Sotos-Prieto M. International Journal of Behavioral Nutrition and Physical Activity. 2022 Jan 27;19(1):8. doi: 10.1186/s12966-021-01219-3. PMID: 35086546

High sensitivity troponins: a potential biomarkers of cardiovascular risk for primary prevention. Leite L, Matos P, Leon-Justel A, Espirito-Santo C, Rodriguez-Padial L, Rodrigues F, Orozco D, Redon J. Frontiers In Cardiovascular Medicine. 2022 Nov 30;9:1054959. doi: 10.3389/fcvm.2022.1054959. PMID: 36531726

Impact of the COVID-19 pandemic on a cancer fast-track programme. Martinez M, Moragon S, Ortega-Morillo B, Monton-Bueno J, Simon S, Rosello S, Insa A, Viala A, Navarro J, Sanmartin A, Fluixa C, Julve A, Soriano D, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner M, Cano A, Silvestre A, Teruel A, Bermejo B, Cervantes A, Chirivella Gonzalez I. Cancer Control. 2022 Jan-Dec;29:10732748221131000. doi: 10.1177/10732748221131000. PMID: 36355430

Incidence and impact of atrial fibrillation in heart failure patients: real-world data in a large community. Diaz J, Martinez F, Calderon JM, Fernandez A, Sauri I, Uso R, Trillo JL, Redon J, Forner MJ. ESC Heart Failure. 2022 Dec;9(6):4230-4239. doi: 10.1002/ehf2.14124. PMID: 36111519

Insights from matched office and ambulatory blood pressure in youth: clinical relevance. Lurbe E, Redon J, Alvarez J, Grau-Perez M, Martinez F, Mancia G. Hypertension. 2022 Mar 29;101161HYPERTENSIONAHA12218993. doi: 10.1161/HYPERTENSIONAHA.122.18993. PMID: 35345885

Integrating clinics, laboratory, and imaging for the diagnosis of common variable immunodeficiency-related granulomatous-lymphocytic interstitial lung disease. Cabanero-Navalon M, Garcia-Bustos V, Forero-Naranjo L, Baettig-Arriagada E, Nunez-Beltran M, Canada-Martinez A, Giner M, Catalan-Caceres N, Frances M, Moral P. Frontiers in Immunology. 2022 Feb 23;13:813491. doi: 10.3389/fimmu.2022.813491. PMID: 35281075

Levels and determinants of urinary cadmium in general population in Spain: Metal-MCC-Spain study. Munoz J, Lope V, Fernandez de Larrea-Baz N, Gomez-Ariza J, Dierssen-Sotos T, Fernandez-Tardon G, Aragones N, Amiano P, Gomez-Acebo I, Tardon A, Grau-Perez M, Garcia-Barrera T, Kogevinas M, Pollan M, Perez-Gomez B. Environmental Research. 2022 Feb 19;210:112959. doi: 10.1016/j.envres.2022.112959. PMID: 35189102

Lipoprotein profiles of fat distribution and its association with insulin sensitivity. Wei D, Marrachelli V, Melgarejo J, Liao C, Janssens S, Verhamme P, Vanassche T, Van Aelst L, Monleon D, Redon J, Zhang Z. Frontiers in Endocrinology. 2022 Oct 25;13:978745. doi: 10.3389/fendo.2022.978745. PMID: 36387872

Mesenchymal stem cell-derived extracellular vesicles as non-coding RNA therapeutic vehicles in autoimmune diseases. Martinez-Arroyo O, Ortega A, Forner M, Cortes R. Pharmaceutics. 2022 Mar 29;14(4):733. doi: 10.3390/pharmaceutics14040733. PMID: 35456567

Narrative update of clinical trials with antihypertensive drugs in children and adolescents. Redon J, Seeman T, Pall D, Suurorg L, Kamperis K, Erdine S, Wuhl E, Mancia G. Frontiers In Cardiovascular Medicine. 2022 Nov 21;9:1042190. doi: 10.3389/fcvm.2022.1042190. PMID: 36479567

New insights of cardiovascular and renal protection in diabetic chronic kidney disease with finerenone. Redon J. Cardiovascular Research. 2022 Mar 25;118(5):e36-e37. doi: 10.1093/cvr/cvac024. PMID: 35333317

Non-invasive vagus nerve stimulation for COVID-19: results from a randomized controlled trial (SAVIOR I). Tornero C, Pastor E, Garzando M, Orduna J, Forner M, Bocigas I, Cedeno D, Vallejo R, McClure C, Czura C, Liebler E, Staats P. Frontiers in Neurology. 2022 Apr 8;13:820864. doi: 10.3389/fneur.2022.820864. PMID: 35463130

Predictors of low-level HIV viraemia and virological failure in the era of integrase inhibitors: a Spanish nationwide cohort. Alvarez H, Rava M, Martinez C, Portilla J, Peraire J, Rivero A, Cervero M, Marino A, Poveda E, Llibre J, CoRIS Study Group, Ferrer Ribera A, CoRIS Study Group. HIV. Medicine. 2022 Sep;23(8):825-836. doi: 10.1111/hiv.13265. PMID: 35234328

Progress in the quality of care for newly diagnosed people with HIV in Spain (2004-2019). Alejos B, Díez C, Galindo MJ, López JC, Moreno-García E, Estrada V, Poveda E, Omar M, Jarrín I, Berenguer J; For CoRIS. Antiviral Therapy. 2022 Aug;27(4):13596535221112729. doi: 10.1177/13596535221112729. PMID: 35802475

Real world data of anticoagulant treatment in non-valvular atrial fibrillation across renal function status. Calderon J, Martinez F, Fernandez A, Sauri I, Diaz J, Uso R, Trillo J, Redon J, Forner M. Scientific reports. 2022 Apr 12;12(1):6123. doi: 10.1038/s41598-022-10164-5. PMID: 35414001

Real-world data of anticoagulant treatment in non-valvular atrial fibrillation. Calderon J, Martinez F, Diaz J, Fernandez A, Sauri I, Uso R, Trillo J, Vela S, Bea C, Redon J, Forner M. Frontiers In Cardiovascular Medicine. 2022 Jan 21;8:733300. doi: 10.3389/fcvm.2021.733300. PMID: 35127843

Shorter time to discontinuation due to treatment failure in people living with HIV switched to dolutegravir plus either rilpivirine or lamivudine compared with integrase inhibitor-based triple therapy in a large Spanish cohort. Teira R, Diaz-Cuervo H, Aragao F, Castano M, Romero A, Roca B, Montero M, Galindo M, Munoz-Sanchez M, Espinosa N, Peraire J, Martinez E, De la Fuente B, Domingo P, Deig E, Merino M, Geijo P, Estrada V, Sepulveda M, Garcia J, Berenguer J, Curran A. Infectious Diseases and Therapy. 2022 Jun;11(3):1177-1192. doi: 10.1007/s40121-022-00630-y. PMID: 35399147

Temporal trends and geographic variability in the prescription of antiretroviral treatments in people living with HIV in Spain, 2004-2020. Ruiz-Alguero M, Hernando V, Riero M, Blanco Ramos J, de Zarraga Fernandez M, Galindo P, Perez-Gonzalez A, Diaz A, Suarez-Garcia I, Jarrin I, CoRIS Cohort. Journal of Clinical Medicine. 2022 Mar 29;11(7):1896. doi: 10.3390/jcm11071896. PMID: 35407504

The prevalence of high blood pressure and its determinants among Tunisian adolescents. Soua S, Ghammam R, Maatoug J, Zammit N, Ben Fredj S, Martinez F, Ghannem H. Journal of Human Hypertension. 2022 Apr 8. doi: 10.1038/s41371-022-00677-x. PMID: 35396537

Thiopurine adherence: high prevalence with low impact in UC outcomes. Gomez-Medina C, Capilla-Lozano M, Ballester Ferre M, Marti-Aguado D, Crespo A, Bosca-Watts M, Navarro Cortes P, Anton R, Pascual Moreno I, Tosca Cuquerella J, Minguez Perez M. Revista Española de Enfermedades Digestivas. 2022 Feb;114(2):76-82. doi: 10.17235/reed.2021.7630/2020. PMID: 33733802

Toxic metals and subclinical atherosclerosis in carotid, femoral, and coronary vascular territories: the aragon workers health study. Grau-Perez M, Caballero-Mateos MJ, Domingo-Relloso A, Navas-Acien A, Gomez-Ariza JL, Garcia-Barrera T, Leon-Latre M, Soriano-Gil Z, Jarauta E, Cenarro A, Moreno-Franco B, Laclaustra M, Civeira F, Casasnovas JA, Guallar E, Tellez-Plaza M. Arteriosclerosis, Thrombosis, And Vascular Biology. 2022 Jan;42(1):87-99. doi: 10.1161/ATVBAHA.121.316358. PMID: 34879710

Urinary zinc and incident type 2 Diabetes: prospective evidence from the Strong Heart Study. Galvez-Fernandez M, Powers M, Grau-Perez M, Domingo-Relloso A, Lolacono N, Goessler W, Zhang Y, Fretts A, Umans JG, Maruthur N, Navas-Acien A. Diabetes care. 2022 Nov 1;45(11):2561-2569. doi: 10.2337/dc22-1152. PMID: 36134919

Use of generic antiretroviral drugs and single-tablet regimen de-simplification for the treatment of HIV infection in Spain. Ruiz-Alguero M, Alejos B, Yubero C, Jaume M, Iribarren J, Asensi V, Pasquau F, Galera C, Pascual-Carrasco M, Munoz A, Jarrin I, Ferrer Ribera A, Galindo Puerto M, Suarez-Garcia I. AIDS Research and Human Retroviruses. 2022 Jun;38(6):433-440. doi: 10.1089/AID.2021.0122. PMID: 35357907

A new score unveils a high prevalence of mild cognitive impairment in patients with nonalcoholic fatty liver disease. Gimenez-Garzo C, Fiorillo A, Ballester-Ferre M, Gallego J, Casanova-Ferrer F, Urios A, Benlloch S, Marti-Aguado D, San-Miguel T, Tosca J, Rios M, Monton C, Durban L, Escudero-Garcia D, Aparicio L, Felipo V, Montoliu C. Journal of Clinical Medicine. 2021 Jun 25;10(13):2806. doi: 10.3390/jcm10132806. PMID: 34202269

Adaptive immune responses to SARS-CoV-2 in recovered severe COVID-19 patients. Olea B, Albert E, Torres I, Amat P, Remigia M, Gozalbo-Rovira R, Rodriguez-Diaz J, Buesa J, Blasco M, Redon J, Signes-Costa J, Navarro D. Journal of Clinical Virology. 2021 Sep;142:104943. doi: 10.1016/j.jcv.2021.104943. PMID: 34391981

Analysis of LDL and HDL size and number by nuclear magnetic resonance in a healthy working population: the LipoLab Study.. Pallares-Carratala V, Quesada J, Orozco-Beltran D, Amigo-Grau N, Lopez-Pineda A, Fernandez Gimenez A, Gil-Guillen V, Correig X, Masana L, Monleon Salvado D, Redón Mas J, Pascual R, Carratala-Munuera C. International Journal of Clinical Practice. 2021 Jan;75(1):e13610. doi: 10.1111/ijcp.13610. PMID: 32648987

Anthropometric indicators as a tool for diagnosis of obesity and other health risk factors: a literature review. Piqueras P, Ballester A, Dura-Gil J, Martinez-Hervas S, Redon J, Real J. Frontiers in Psychology. 2021 Jul 9;12:631179. doi: 10.3389/fpsyg.2021.631179. PMID: 34305707

Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The Hortega study. Galvez-Fernandez M, Grau-Perez M, Garcia-Barrera T, Ramirez-Acosta S, Gomez-Ariza J, Perez-Gomez B, Galan-Labaca I, Navas-Acien A, Redon J, Briongos-Figuero L, Duenas-Laita A, Perez-Castrillon J, Tellez-Plaza M, Martin-Escudero J. Free Radical Biology & Medicine. 2021 Jan;162:392-400. doi: 10.1016/j.freeradbiomed.2020.10.318. PMID: 33137469

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes. Pitt B, Filippatos G, Agarwal R, Anker SD, Bakris GL, Rossing P, Joseph A, Kolkhof P, Nowack C, Schloemer P, Ruilope LM, FIGARO-DKD Investigators. New England Journal of Medicine. 2021 Dec 9;385(24):2252-2263. doi: 10.1056/NEJMoa2110956. PMID: 34449181

Cardiovascular outcomes in patients at high cardiovascular risk with previous myocardial infarction or stroke. Boehm M, Schumacher H, Teo KK, Lonn EM, Lauder L, Mancia G, Redon J, Schmieder RE, Sliwa K, Marx N, Weber MA, Williams B, Yusuf S, Mann JF, Mahfoud F. Journal of Hypertension. 2021 Aug 1;39(8):1602-1610. doi: 10.1097/HJH.0000000000002822. PMID: 34188004

Cardiovascular system in the sars-CoV-2: impact of therapies. Redon J. Journal of Hypertension. 2021 Jul 1;39(7):1306-1308. doi: 10.1097/HJH.0000000000002860. PMID: 34074967

Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2. Ferrer MD, Sanchez Barrueco A, Martinez-Beneyto Y, Mateos-Moreno MV, Ausina-Marquez V, Garcia-Vazquez E, Puche-Torres M, Forner Giner MJ, Campos Gonzalez A, Santillan Coello JM, Alcala Rueda I, Villacampa Auba JM, Cenjor Espanol C, Lopez Velasco A, Santolaya Abad D, Garcia-Esteban S, Artacho A, Lopez-Labrador X, Mira A. Scientific Reports. 2021 Dec 22;11(1):24392. doi: 10.1038/s41598-021-03461-y. PMID: 34937855

Cost of Type 2 diabetes patients with chronic kidney disease based on real-world data: an observational population-based study in Spain. Uso-Talamantes R, Gonzalez-de-Julian S, Diaz-Carnicero J, Sauri-Ferrer I, Trillo-Mata J, Carrasco-Perez M, Navarro-Perez J, Gorriz J, Vivas-Consuelo D, Redon J. International Journal of Environmental Research and Public Health. 2021 Sep 18;18(18):9853. doi: 10.3390/ijerph18189853. PMID: 34574782

Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. Berenguer J, Borobia AM, Ryan P, Rodríguez-Baño J, Bellón JM, Jarrín I, Carratalà J, Pachón J, Carcas AJ, Yllescas M, Arribas JR; COVID-19@Spain and COVID@HULP Study Groups. Thorax. 2021 Feb 25:thoraxjnl-2020-216001. doi: 10.1136/thoraxjnl-2020-216001. PMID: 33632764

Digital pathology: accurate technique for quantitative assessment of histological features in metabolic-associated fatty liver disease. Marti-Aguado D, Rodriguez-Ortega A, Mestre-Alagarda C, Bauza M, Valero-Perez E, Alfaro-Cervello C, Benlloch S, Perez-Rojas J, Ferrandez A, Alemany-Monraval P, Escudero-Garcia D, Monton C, Aguilera V, Alberich-Bayarri A, Serra M, Marti-Bonmati L. Alimentary Pharmacology & Therapeutics. 2021 Jan;53(1):160-171. doi: 10.1111/apt.16100. PMID: 32981113

Dynamics of creatinine estimated glomerular filtration rate using one or more antiretrovirals that inhibit creatinine tubular secretion. Perez Elias MJ, Alejos B, Gutierrez MM, Crespo M, De Los Santos Gil I, Ribera E, Galindo MJ, Lozano F, Payeras Cifre A, Boix V, Montero-Alonso M, Sanz J, De La Torre Lima J, Palacios R, De La Fuente Moral S, Martinez E; Codar Study Group. Journal of Antimicrobial Chemotherapy. 2021 Mar 12;76(4):1046-1050. doi: 10.1093/jac/dkaa547. PMID: 33501995

Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes. Nunez-Gil I, Fernandez-Ortiz A, Maroud Eid C, Huang J, Romero R, Becerra-Munoz V, Uribarri A, Feltes G, Trabatoni D, Fernandez-Rozas I, Viana-Llamas M, Pepe M, Cerrato E, Bertaina M, Capel Astrua T, Alfonso E, Castro-Mejia A, Raposeiras-Roubin S, D’Ascenzo F, Espejo Paeres C, Signes-Costa J, Bardaji A, Fernandez-Perez C, Marin F, Fabregat-Andres O, Akin I, Estrada V, Macaya C. Cardiology Journal. 2021 Feb 11;42(6):700-710. doi: 10.1093/eurheartj/ehaa943. PMID: 33351892

Effects of HCV Eradication on Bone mineral density in HIV/HCV Coinfected Patients. Carrero, A, Berenguer J, Hontanon V, Guardiola JM, Navarro J, von Wichmann MA, Tellez MJ, Quereda C, Santos I, Sanz J, Galindo MJ, Hernandez Quero J, Jimenez Sousa MA, Perez Latorre L, Bellon JM, Resino S, Esteban H, Martinez E, Gonzalez Garcia J. Clinical Infectious Diseases. 2021 Oct 5;73(7):e2026-e2033. doi: 10.1093/cid/ciaa1396. PMID: 32930720

eGFR-EPI changes among HIV patients who switch from F/TDF to F/TAF while maintaining the same third agent in the Spanish VACH cohort. Teira R, Diaz-Cuervo H, Aragão F, Muñoz J, Galindo P, Merino M, de la Fuente B, Sepúlveda MA, Domingo P, García J, Castaño M, Ribera E, Geijo P, Romero A, Peraire J, Deig E, Roca B, Martínez E, Estrada V, Montero M, Berenguer J, Espinosa N. HIV Research & Clinical Practice. 2021 Jun;22(3):78-85. PMID: 34410219‘ target=’_blank’>34410219

Genetic variation and urine cadmium levels: ABCC1 effects in the Strong Heart Family Study. Grau-Perez M, Voruganti V, Balakrishnan P, Haack K, Goessler W, Franceschini N, Redon J, Cole S, Navas-Acien A, Tellez-Plaza M. Environmental pollution. 2021 Feb 11;276:116717. doi: 10.1016/j.envpol.2021.116717. PMID: 33640655

HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients. Brochado Ó, Martínez I, Berenguer J, Medrano L, González-García J, Jiménez-Sousa MÁ, Carrero A, Hontañón V, Navarro J, Guardiola JM, Fernández-Rodríguez A, Resino S; GESIDA Study Group. Journal of Biomedical Science. 2021 Mar 30;28(1):23. doi: 10.1186/s12929-021-00718-6. PMID: 33785040

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. NCD Risk Factor Collaboration NCD. ELife. 2021 Mar 9;10:e60060. doi: 10.7554/eLife.60060. PMID: 33685583

IgA-dominant infection-associated glomerulonephritis following SARS-CoV-2 infection. Perez A, Torregrosa I, D’Marco L, Juan I, Terradez L, Solis M, Moncho F, Carda-Batalla C, Forner M, Gorriz J. Viruses-Basel. 2021 Mar 31;13(4):587. doi: 10.3390/v13040587. PMID: 33807151

Immunoglobulin G4-related aortitis and severe aortic valve stenosis treated with transcatheter aortic valve replacement and immunosuppression. Viana D, Marcos-Garces V, Blas S, Fores J, Romano J, Baena J, Giner M, Suarez N, Chorro F, Fornas F. Canadian Journal of Cardiology. 2021 Nov;37(11):1873-1876. doi: 10.1016/j.cjca.2021.07.015. PMID: 34333027

Impact of obesity in kidney diseases. Kotsis V, Martinez F, Trakatelli C, Redon J. Nutrients. 2021 Dec 15;13(12):4482. doi: 10.3390/nu13124482. PMID: 34960033

Insights into glomerular filtration and albuminuria. Redon J, Selma-Soriano E, Cortes R. New England Journal of Medicine. 2021 Jul 29;385(5):477-478. doi: 10.1056/NEJMc2108129. PMID: 34320301

Kinetics of emergence of liver complications in HCV-infected patients and advanced fibrosis, with and without HIV-coinfection, after SVR. Corma-Gomez A, Macias J, Tellez F, Morano L, Rivero A, Serrano M, Rios MJ, Vera-Mendez FJ, Santos M, Real LM, Palacios R, Santos I, Geijo P, Imaz A, Merino D, Galindo MJ, Reus-Banuls S, Lopez-Ruz MA, Galera C, Pineda JA. AIDS (London, England). 2021 Nov 1;35(13):2119-2127. doi: 10.1097/QAD.0000000000002959. PMID: 34049354

Liver stiffness-based strategies predict absence of variceal bleeding in cirrhotic HCV-infected patients with and without HIV-coinfection after sustained virological response. Corma Gomez A, Macias J, Morano L, Rivero A, Tellez F, Rios MJ, Santos M, Serrano M, Palacios R, Merino D, Real LM, De Los Santos I, Vera Mendez FJ, Galindo MJ, Pineda JA. Clinical Infectious Diseases. 2021 Mar 1;72(5):e96-e102. doi: 10.1093/cid/ciaa1726. PMID: 33211801

Metal exposure and biomarker levels among e-cigarette users in Spain. Olmedo P, Rodrigo L, Grau-Perez M, Hilpert M, Navas-Acien A, Tellez-Plaza M, Pla A, Gil F. Environmental Research. 2021 Jul 10;202:111667. doi: 10.1016/j.envres.2021.111667. PMID: 34256077

Precise whole liver automatic segmentation and quantification of PDFF and R2* on MR images. Jimenez-Pastor A, Alberich-Bayarri A, Lopez-Gonzalez R, Marti-Aguado D, Frana M, Bachmann R, Mazzucco J, Marti-Bonmati L. European Radiology. 2021 Oct;31(10):7876-7887. doi: 10.1007/s00330-021-07838-5. PMID: 33768292

Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain. Castro-Granell V, Garin N, Jaén Á, Cenoz S, Galindo MJ, Fuster-RuizdeApodaca MJ. PLoS One. 2021 Nov 19;16(11):e0260334. doi: 10.1371/journal.pone.0260334. PMID: 34797882

Prognostic value of diagnostic scales in community-acquired sepsis mortality at an emergency service. Prognosis in community-adquired sepsis. Clar J, Oltra MR, Benavent R, Pinto C, Ruiz A, Sanchez MT, Noceda J, Redon J, Forner MJ. BMC Emergency Medicine. 2021 Dec 18;21(1):161. doi: 10.1186/s12873-021-00532-1. PMID: 34922448

Rabphilin silencing causes dilated cardiomyopathy in a Drosophila model of nephrocyte damage. Selma-Soriano E, Casillas-Serra C, Artero R, Llamusi B, Navarro J, Redon J. Scientific Reports. 2021 Jul 27;11(1):15287. doi: 10.1038/s41598-021-94710-7. PMID: 34315987

Real world effectiveness of standard of care triple therapy versus two-drug combinations for treatment of people living with HIV. Teira R, Diaz-Cuervo H, Aragão F, Marguet S, de la Fuente B, Muñoz MJ, Abdulghani N, Ribera E, Domingo P, Deig E, Peraire J, Roca B, Montero M, Galindo MJ, Romero A, Espinosa N, Lozano F, Merino MD, Martínez E, Geijo P, Estrada V, García J, Sepúlveda MA, Berenguer J. PLoS One. 2021 Apr 8;16(4):e0249515. doi: 10.1371/journal.pone.0249515. PMID: 33831047

Renal function and attributable risk of death and cardiovascular hospitalization in participants with diabetes from a registry-based cohort. Ruiz-Quintero M, Redón Mas J, Tellez-Plaza M, Cebrian-Cuenca A, Navarro Perez J, Menendez E, Perez-Navarro A, Fernandez-Gimenez A, Lopez-Pineda A, Quesada J, Pallares-Carratala V, Gil-Guillen V, Martín Moreno J, Bleda-Cano J, Carrascosa S, Carratala-Munuera C. Primary Care Diabetes. 2021 Feb;15(1):88-94. doi: 10.1016/j.pcd.2020.06.004. PMID: 32646765

Renal outcomes and blood pressure patterns in diabetic and nondiabetic individuals at high cardiovascular risk. Bohm M, Schumacher H, Teo K, Lonn E, Mahfoud F, Emrich I, Mancia G, Redon J, Schmieder R, Sliwa K, Lehrke M, Marx N, Weber M, Williams B, Yusuf S, Mann J. Journal of Hypertension. 2021 Apr 1;39(4):766-774. doi: 10.1097/HJH.0000000000002697. PMID: 33560052

Risk factors and management strategies associated with non-response to aminosalicylates for maintenance treatment in ulcerative colitis. Marti-Aguado D, Ballester M, Minguez M. Revista Espanola de Enfermedades Digestivas. 2021 Jun;113(6):447-453. doi: 10.17235/reed.2021.7797/2021. PMID: 33569968

SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with Coronavirus Disease 2019. Gimenez Quiles E, Albert Vicent E, Torres Fink I, Remigia Pellicer M, Alcaráz Soriana M, Galindo Puerto M, Blasco Cortes M, Solano Vercet C, Forner Giner M, Redón Mas J, Signes-Costa Miñana J, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):375-382. doi: 10.1002/jmv.26213. PMID: 32579268

Self-rated health among people living with HIV in Spain in 2019: a cross-sectional study. Ruiz-Alguero M, Hernando V, Marcos H, Gutierrez G, Perez-Elias M, de Quiros J, Pulido F, Gorgolas M, Sanz J, Suarez-Garcia I, Fernandez M, Losa J, Perez J, Ladrero M, Prieto M, Gonzalez G, Izquierdo A, Viloria L, Lopez I, Martinez E, Castrillejo D, Aranguren R, Belmonte M, Aranda-Garcia I, Arraiza A, Diaz A, Hospital Survey Study Group, Hop Survey Study Grp. BMC Infectious Diseases. 2021 Jan 30;21(1):129. doi: 10.1186/s12879-021-05815-3. PMID: 33516173

Small Rab GTPases in intracellular vesicle trafficking: the case of Rab3A/Raphillin-3a complex in the kidney. Martinez-Arroyo O, Selma-Soriano E, Ortega A, Cortes R, Redon J. International Journal of Molecular Sciences. 2021 Jul 18;22(14):7679. doi: 10.3390/ijms22147679. PMID: 34299299

Sources of psychological distress among primary care physicians during the COVID-19 pandemic’s first wave in Spain: a cross-sectional study. Cebrian-Cuenca A, Mira J, Caride-Miana E, Fernandez-Jimenez A, Orozco-Beltran D. Primary Health Care Research & Development. 2021 Oct 18;22:e55. doi: 10.1017/S1463423621000566. PMID: 34658322

Supervised Analysis for Phenotype Identification: The Case of Heart Failure Ejection Fraction Class. Lopez C, Holgado JL, Cortes R, Sauri I, Fernandez A, Calderon JM, Nuñez J, Redon J. Bioengineering. 2021 Jun 21;8(6):85. doi: 10.3390/bioengineering8060085. PMID: 34205745

Ten-year assessment of a cancer fast-track programme to connect primary care with oncology: reducing time from initial symptoms to diagnosis and treatment initiation. Martinez MT, Monton-Bueno J, Simon S, Ortega B, Moragon S, Rosello S, Insa A, Navarro J, Sanmartin A, Julve A, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner MJ, Cano A, Silvestre A, Teruel A, Lluch A, Cervantes A, Chirivella Gonzalez I. ESMO open. 2021 May 11;6(3):100148. doi: 10.1016/j.esmoop.2021.100148. PMID: 33989988

The Experience With Health Care of Patients With Inflammatory Arthritis: A Cross-sectional Survey Using the Instrument to Evaluate the Experience of Patients With Chronic Diseases. de Toro J, Cea-Calvo L, García-Vivar ML, Pantoja L, Lerín-Lozano C, García-Díaz S, Galindo MJ, Marín-Jiménez I, Fernández S, Mestre Y, Orozco-Beltrán D. Journal of Clinical Rheumatology. 2019 Jul 25. doi: 10.1097/RHU.0000000000001155.. PMID: 31356399

Therapeutic Potential of Extracellular Vesicles in Hypertension-Associated Kidney Disease. Martinez-Arroyo O, Ortega A, Redon J, Cortes R. Hypertension. 2021 Jan;77(1):28-38. doi: 10.1161/HYPERTENSIONAHA.120.16064. PMID: 33222549

Transjugular intrahepatic portosystemic shunt reduces hospital care burden in patients with decompensated cirrosis. Ballester M, Lluch P, Gomez C, Capilla M, Tosca J, Marti-Aguado D, Guijarro J, Minguez M. Internal and Emergency Medicine. 2021 Sep;16(6):1519-1527. doi: 10.1007/s11739-020-02602-x. PMID: 33400160

Urinary exosomal miR-146a as a marker of albuminuria, activity changes and disease flares in lupus nephritis. Perez Hernandez J, Martínez Arroyo O, Ortega Gutiérrez A, Galera Martos M, Solis Salguero M, Chaves Martínez F, Redón Mas J, Forner Giner M, Cortés Vergaz R. Journal Of Nephrology. 2021 Aug;34(4):1157-1167. doi: 10.1007/s40620-020-00832-y. PMID: 32803682

Urinary- and Plasma-Derived Exosomes Reveal a Distinct MicroRNA Signature Associated With Albuminuria in Hypertension. Perez-Hernandez J, Riffo-Campos A, Ortega A, Martinez-Arroyo O, Perez-Gil D, Olivares D, Solaz E, Martinez F, Martinez-Hervas S, Chaves F, Redon J, Cortes R. Hypertension. 2021 Mar 3;77(3):960-971. doi: 10.1161/HYPERTENSIONAHA.120.16598. PMID: 33486986

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. NCD Risk Factor Collaboration. Lancet. 2021 Sep 11;398(10304):957-980. doi: 10.1016/S0140-6736(21)01330-1. PMID: 34450083

Projects
Reference: 101083002- INNDIH
Title: 101083002- INNDIH – Valencia Region Digital Innovation Hub
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2025
Total budget: 225.395,50 €
Reference: 101095480- Hypermarker
Title: Personalised pharmacometabolomic optimisation of treatment for hypertension
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2026
Total budget: 400.000 €
Reference: INTEGRA-CLOUD
Title: Creación de una plataforma abierta de acceso, captura, almacenamiento e intercambio descentralizado de los datos de salud en tiempo real del Departamento de Salud Clínico-Malvarrosa para la computación cloud-edge de sistemas predictivos, de toma de decisiones y de inteligencia artificial
Funding body: Ministerio de Asuntos Económicos y Transformación Digital
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2025
Total budget: 5.252.274 €
Reference: EHDEN – OMOP
Title: EHDEN. Harmonization Fund Holder
Funding body: European Commission (3rd Health Program)
Principal Investigator: Josep Redón i Mas
Duration: 2022 – 2023
Total budget: 50.000,00 €
Reference: PI21/00249
Title: Identificación de ARN no codificantes en biopsia líquida con énfasis en exosomas como biomarcadores pronóstico de actividad en el lupus eritematoso sistémico. Implicación fisiopatológica en el daño renal
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Raquel Cortés Vergaz, Mª José Forner Giner
Duration: 2022 – 2024
Total budget: 135.520 €
Reference: 945097-WELLBASED
Title: WELLBASED. Improving health, wellbeing and equality by evidenced-based urban policies for tackling energy poverty
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2021 – 2025
Total budget: 395.250,00 €
Reference: PI19/01796
Title: Implicaciones experimentales y clinicas del complejo proteico rabphilin-rab en daño renal en la diabetes mellitus tipo 2
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2020 – 2023
Total budget: 196.020 €
Reference: PI18/01405
Title: Perfil de microRNAs exosomales y su valor pronostico a largo plazo en el lupus eritematoso sistemico. Asociacion con marcadores establecidos de daño renal
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Raquel Cortés Vergaz, Maria José Forner
Duration: 2019 – 2021
Total budget: 111.320 €
Reference: 780495-BigMedilytics
Title: Big Data for Medical Analytics
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 1.062.136 €
Reference: BodyPass
Title: API-ecosystem for cross-sectorial exchange of 3D personal data
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 351937,5
Reference: PT17/0005/0017
Title: Plataforma de Innovación
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 38.985 €
Reference: BigData@Heart
Title: Big Data for Better Hearts
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2017 – 2022
Total budget: 386250
Reference: PI16/01402
Title: Estudio experimental in vivo e in vitro y la aplicación clínica del impacto de las proteínas del complejo Rhabphilin-Rab en el desarrollo del daño renal y cardiovascular
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2017 – 2019
Total budget: 194.205 €
Reference: PROMETEO/2016/084
Title: Innovación tecnológica en la evaluación del sistema nervioso simpático en adolescentes y adultos jóvenes obesos: papel en la estratificación del riesgo e intervención terapéutica
Funding body: Conselleria de Educación, Cultura y Deporte
Principal Investigator: Josep Redón i Mas
Duration: 2016 – 2019
Total budget: 246.190 €
Reference: ADVANTAGE
Title: Managing Frailty. A comprehensive approach to promote a disability-free advanced age in Europe: the ADVANTAGE initiative
Funding body: European Commission (3rd Health Program)
Principal Investigator: Josep Redón i Mas, José Viña Ribes
Duration: 2016 – 2019
Total budget: 130.005 €
+ Info
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Endorsed by the European Renal Association (ERA) and the International Society of Hypertension (ISH). Mancia Chairperson G, Kreutz Co-Chair R, Brunstrom M, Burnier M, Grassi G, Januszewicz A, Muiesan M, Tsioufis K, Agabiti-Rosei E, Algharably E, Azizi M, Benetos A, Borghi C, Hitij J, Cifkova R, Coca A, Cornelissen V, Cruickshank K, Cunha P, Danser A, de Pinho R, Delles C, Dominiczak A, Dorobantu M, Doumas M, Fernandez-Alfonso M, Halimi J, Jarai Z, Jelakovic B, Jordan J, Kuznetsova T, Laurent S, Lovic D, Lurbe E, Mahfoud F, Manolis A, Miglinas M, Narkiewicz K, Niiranen T, Palatini P, Parati G, Pathak A, Persu A, Polonia J, Redon J, Sarafidis P, Schmieder R, Spronck B, Stabouli S, Stergiou G, Taddei S, Thomopoulos C, Tomaszewski M, Van de Borne P, Wanner C, Weber T, Williams B, Zhang Z, Kjeldsen S. Journal of Hypertension. 2023 Dec 1;41(12):1874-2071. doi: 10.1097/HJH.0000000000003480. PMID: 37345492

2022 Practice guidelines for the management of arterial hypertension of the Spanish Society of Hypertension. Gorostidi M, Gijón-Conde T, de la Sierra A, Rodilla E, Rubio E, Vinyoles E, Oliveras A, Santamaría R, Segura J, Molinero A, Pérez-Manchón D, Abad M, Abellán J, Armario P, Banegas JR, Camafort M, Catalina C, Coca A, Divisón JA, Domenech M, Martell N, Martín-Rioboó E, Morales-Olivas F, Pallarés V, Pérez de Isla L, Prieto MA, Redón J, Ruilope LM, García-Donaire JA. Hipertensión y Riesgo Vascular. 2022 Oct-Dec;39(4):174-194. doi: 10.1016/j.hipert.2022.09.002. PMID: 36153303

Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513

2018 ESC/ESH Guidelines for the management of arterial. Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I. Kardiologia Polska. 2019;77(2):71-159. doi: 10.5603/KP.2019.0018. PMID: 30816983

Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. Lurbe E, Torró I, Álvarez J, Aguilar F, Mancia G, Redon J, Redon P. Journal of Hypertension. 2019 Dec;37(12):2414-2421. doi: 10.1097/HJH.0000000000002229. PMID: 31688292

Title: Evaluación cardiometabólica y adrenérgica en el sujeto obeso sano joven
Doctoral candidate: Ruiz Hernández, Adrián
Director(s): Forner Giner, Mª José; Redón i Mas, Josep
Date of the defense: 28/04/2022
University: Universitat de València

Title: Monitorización del manejo de sepsis para la identificación de flujos asistenciales y su impacto en la evolución de los pacientes. El diagnóstico precoz de sepsis en urgencias
Doctoral candidate: Clar Bononad, Jorge
Director(s): Oltra Sempere, Mª Rosa; Redón i Mas, Josep
Date of the defense: 10/02/2022
University: Universitat de València

Title: Estudio prospectivo multicéntrico de precisión diagnóstica de los biomarcadores de imagen en las hepatopatías crónicas difusas
Doctoral candidate: Martí Aguado, David
Director(s): Martí Bonmatí, Luis; Serra Desfilis, Miguel Ángel
Date of the defense: 29/06/2021
University: Universitat de València

Title: Valor pronóstico de los cambios en la rigidez arterial en la hipertensión arterial esencial
Doctoral candidate: Calaforra Juan, Oscar
Director(s): Redón Mas, Josep; Forner Giner, María José; Martínez García, Fernando
Date of the defense: 28/07/2020
University: Universitat de València

Title: Sistema de biosensado fotónico para la detección de trombina, alérgenos y patógenos. Funcionalización química de chips fotónicos basados en estructuras de anillos resonantes
Doctoral candidate: Sánchez Sánchez, Carlos
Director(s): Martí Sendra, Javier; Redón Mas, Josep; Peransí Llopis, Sergio Manuel
Date of the defense: 15/11/2019
University: Universitat Politècnica de València

Title: Estudio de la evolución del sellado distal ilíaco en el tratamiento endovascular de la aorta abdominal
Doctoral candidate: Bargay Juan, Pau
Director(s): Redon Mas, Josep; Plaza Martínez, Ángel
Date of the defense: 25/02/2019
University: Universitat de València