Grupo de Estudio de Riesgo Cardiometabólico y Renal

Área de Cardiovascular

Comenzar el análisis de podocitos (identificación, cultivo y fenotipado) y sus derivados: micro-ARN, exosomas

La integración de la metabolómica y la genómica en el estudio de factores relacionados con el desarrollo de daño renal

Desarrollo de estudios de caracterización hemodinámica no invasiva en patología vascular

Análisis de morbilidad y mortalidad ligada a la presencia de hipertensión y lesión renal

Desarrollo de estudios in vitro de adhesión plaquetaria y leucocitaria en tromboembolismo venoso

Estudios genéticos relacionados a la obesidad y al sobrepeso y tromboembolismo venoso

Desarrollo de ensayos clínicos de fase III y IV

Coordinador
Dr. Josep Redón i Mas
josep.redon@uv.es/jredon@uv.es

INVESTIGADORES
R4 Senior

Josep Redón i Mas    

R3 Consolidado

Mª José Forner Giner
Mª José Galindo Puerto
Mª José García-Fuster González-Alegre

R2 Novel / Emergente

Ana Ortega Gutiérrez
Raquel Cortés Vergaz    

R1 Predoctoral

David Martí Aguado
Adrián Ruiz Hernández
Elena Solaz Moreno
Olga Martínez Arroyo

STAFF
Colaborador/a

Cristina López Zumel
Ana Ferrer Albero

Enfermero/a

Laura Cantero Milán

Técnico/a

Alexandra Eugenia Muñoz Oliver
Antonio Fernández Giménez
Noemí Dolz Gilba
Óscar Calaforra Juan

Apoyo
Publicaciones
Analysis of LDL and HDL size and number by nuclear magnetic resonance in a healthy working population: the LipoLab Study.. Pallares-Carratala V, Quesada J, Orozco-Beltran D, Amigo-Grau N, Lopez-Pineda A, Fernandez Gimenez A, Gil-Guillen V, Correig X, Masana L, Monleon Salvado D, Redón Mas J, Pascual R, Carratala-Munuera C. International Journal of Clinical Practice. 2021 Jan;75(1):e13610. doi: 10.1111/ijcp.13610. PMID: 32648987

Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review. Huerta M, Rosello S, Sabater L, Ferrer A, Tarazona N, Roda D, Gambardella V, Alfaro-Cervello C, Garces-Albir M, Cervantes A, Ibarrola-Villava M. Cancers. 2021 Feb 27;13(5):994. doi: 10.3390/cancers13050994. PMID: 33673558

Digital pathology: accurate technique for quantitative assessment of histological features in metabolic-associated fatty liver disease. Marti-Aguado D, Rodriguez-Ortega A, Mestre-Alagarda C, Bauza M, Valero-Perez E, Alfaro-Cervello C, Benlloch S, Perez-Rojas J, Ferrandez A, Alemany-Monraval P, Escudero-Garcia D, Monton C, Aguilera V, Alberich-Bayarri A, Serra M, Marti-Bonmati L. Alimentary Pharmacology & Therapeutics. 2021 Jan;53(1):160-171. doi: 10.1111/apt.16100. PMID: 32981113

Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes. Nunez-Gil I, Fernandez-Ortiz A, Maroud Eid C, Huang J, Romero R, Becerra-Munoz V, Uribarri A, Feltes G, Trabatoni D, Fernandez-Rozas I, Viana-Llamas M, Pepe M, Cerrato E, Bertaina M, Capel Astrua T, Alfonso E, Castro-Mejia A, Raposeiras-Roubin S, D’Ascenzo F, Espejo Paeres C, Signes-Costa J, Bardaji A, Fernandez-Perez C, Marin F, Fabregat-Andres O, Akin I, Estrada V, Macaya C. Cardiology Journal. 2021 Feb 11;42(6):700-710. doi: 10.1093/eurheartj/ehaa943. PMID: 33351892

Genetic variation and urine cadmium levels: ABCC1 effects in the Strong Heart Family Study. Grau-Perez M, Voruganti V, Balakrishnan P, Haack K, Goessler W, Franceschini N, Redon J, Cole S, Navas-Acien A, Tellez-Plaza M. Environmental pollution. 2021 Feb 11;276:116717. doi: 10.1016/j.envpol.2021.116717. PMID: 33640655

Renal function and attributable risk of death and cardiovascular hospitalization in participants with diabetes from a registry-based cohort. Ruiz-Quintero M, Redón Mas J, Tellez-Plaza M, Cebrian-Cuenca A, Navarro Perez J, Menendez E, Perez-Navarro A, Fernandez-Gimenez A, Lopez-Pineda A, Quesada J, Pallares-Carratala V, Gil-Guillen V, Martín Moreno J, Bleda-Cano J, Carrascosa S, Carratala-Munuera C. Primary Care Diabetes. 2021 Feb;15(1):88-94. doi: 10.1016/j.pcd.2020.06.004. PMID: 32646765

Renal outcomes and blood pressure patterns in diabetic and nondiabetic individuals at high cardiovascular risk. Bohm M, Schumacher H, Teo K, Lonn E, Mahfoud F, Emrich I, Mancia G, Redon J, Schmieder R, Sliwa K, Lehrke M, Marx N, Weber M, Williams B, Yusuf S, Mann J. Journal of Hypertension. 2021 Feb 3. doi: 10.1097/HJH.0000000000002697. PMID: 33560052

Risk factors and management strategies associated with non-response to aminosalicylates for maintenance treatment in ulcerative colitis. Marti-Aguado D, Ballester M, Minguez M. Revista Espanola de Enfermedades Digestivas. 2021 Feb 11. doi: 10.17235/reed.2021.7797/2021. PMID: 33569968

SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with Coronavirus Disease 2019. Gimenez Quiles E, Albert Vicent E, Torres Fink I, Remigia Pellicer M, Alcaráz Soriana M, Galindo Puerto M, Blasco Cortes M, Solano Vercet C, Forner Giner M, Redón Mas J, Signes-Costa Miñana J, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):375-382. doi: 10.1002/jmv.26213. PMID: 32579268

The Experience With Health Care of Patients With Inflammatory Arthritis: A Cross-sectional Survey Using the Instrument to Evaluate the Experience of Patients With Chronic Diseases. de Toro J, Cea-Calvo L, García-Vivar ML, Pantoja L, Lerín-Lozano C, García-Díaz S, Galindo MJ, Marín-Jiménez I, Fernández S, Mestre Y, Orozco-Beltrán D. Journal of Clinical Rheumatology. 2019 Jul 25. doi: 10.1097/RHU.0000000000001155.. PMID: 31356399

Therapeutic Potential of Extracellular Vesicles in Hypertension-Associated Kidney Disease. Martinez-Arroyo O, Ortega A, Redon J, Cortes R. Hypertension. 2021 Jan;77(1):28-38. doi: 10.1161/HYPERTENSIONAHA.120.16064. PMID: 33222549

Transjugular intrahepatic portosystemic shunt reduces hospital care burden in patients with decompensated cirrosis. Ballester M, Lluch P, Gomez C, Capilla M, Tosca J, Marti-Aguado D, Guijarro J, Minguez M. Internal and Emergency Medicine. 2021 Jan 5. doi: 10.1007/s11739-020-02602-x. PMID: 33400160

Urinary- and Plasma-Derived Exosomes Reveal a Distinct MicroRNA Signature Associated With Albuminuria in Hypertension. Perez-Hernandez J, Riffo-Campos A, Ortega A, Martinez-Arroyo O, Perez-Gil D, Olivares D, Solaz E, Martinez F, Martinez-Hervas S, Chaves F, Redon J, Cortes R. Hypertension. 2021 Mar 3;77(3):960-971. doi: 10.1161/HYPERTENSIONAHA.120.16598. PMID: 33486986

Acute kidney injury in heart failure: a population study. Holgado Sánchez J, Lopez Forte C, Fernández Giménez A, Saurí Ferrer M, Uso Talamantes R, Trillo Mata J, Vela Bernal S, Nuñez Villota J, Redón Mas J, Ruiz Hernandez A. Esc Heart Failure. 2020 Apr;7(2):415-422. doi: 10.1002/ehf2.12595. PMID: 32059081

Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The Hortega study. Galvez-Fernandez M, Grau-Perez M, Garcia-Barrera T, Ramirez-Acosta S, Gomez-Ariza J, Perez-Gomez B, Galan-Labaca I, Navas-Acien A, Redon J, Briongos-Figuero L, Duenas-Laita A, Perez-Castrillon J, Tellez-Plaza M, Martin-Escudero J. Free Radical Biology & Medicine. 2020 Oct 30;S0891-5849(20)31592-6. doi: 10.1016/j.freeradbiomed.2020.10.318. PMID: 33137469

Cardiac magnetic resonance-derived fibrosis, strain and molecular biomarkers of fibrosis in hypertensive heart disease. Pichler G, Redon J, Martinez F, Solaz E, Calaforra O, Andres M, Lopez B, Diez J, Oberbauer R, Adlbrecht C, Karth G, Maceira A. Journal of Hypertension. 2020 Oct;38(10):2036-2042. doi: 10.1097/HJH.0000000000002504. PMID: 32890280

Cardiac sarcoidosis as an incidental finding: A case report. Gabaldon-Perez A, Garcia-Blas S, Forner M, Lopez-Lereu M, Bonanad C. Heart & Lung. 2020;49(6):783-787. doi: 10.1016/j.hrtlng.2020.09.009. PMID: 32980628

Chronic kidney disease as a cardiovascular risk factor. Carmena Rodriguez R, Ascaso Gimilio J, Redón Mas J. Journal of Hypertension. 2020 Nov;38(11):2110-2121. doi: 10.1097/HJH.0000000000002506. PMID: 32649622

Co-detection of respiratory pathogens in patients hospitalized with Coronavirus viral disease-2019 pneumonia. Blasco Cortes M, Buesa Gomez J, Colomina Rodríguez F, Forner Giner M, Galindo Puerto M, Navarro Perez J, Noceda Bermejo J, Redón Mas J, Signes-Costa Miñana J, Navarro Ortega D. Journal Of Medical Virology. 2020 Oct;92(10):1799-1801. doi: 10.1002/jmv.25922. PMID: 32320082

Decreased Urinary Levels of SIRT1 as Non-Invasive Biomarker of Early Renal Damage in Hypertension. Martínez Arroyo O, Ortega Gutiérrez A, Galera Martos M, Solaz Moreno E, Martinez Hervas S, Redón Mas J, Cortés Vergaz R. International Journal of Molecular Sciences. 2020 Sep 2;21(17):6390. doi: 10.3390/ijms21176390. PMID: 32887498

Drug use and antiretroviral therapy (ART) interactions: a qualitative study to explore the knowledge, beliefs, adherence, and quality of life of people living with HIV taking ART and illicit drugs. Fuster-Ruiz de Apodaca MJ, Castro-Granell V, Laguia A, Jaen A, Cenoz S, Galindo Puerto M. AIDS Research and Therapy. 2020 May 24;17(1):24. doi: 10.1186/s12981-020-00279-y. PMID: 32448214

Effectiveness and safety of first-line antiretroviral regimens in clinical practice: a multicentre cohort study. Alejos B, Suarez-Garcia I, Rava M, Bautista-Hernandez A, Gutierrez F, Dalmau D, Sagastagoitia I, Rivero A, Moreno S, Jarrin I, CoRIS. The Journal of Antimicrobial Chemotherapy. 2020 Oct 1;75(10):3004-3014. doi: 10.1093/jac/dkaa246. PMID: 32667674

Effects of Eradication of HCV on Cardiovascular Risk and Preclinical Atherosclerosis in HIV/HCV-Coinfected Patients. Carrero A, Berenguer J, Hontanon V, Navarro J, Hernandez-Quero J, Galindo Puerto M, Quereda C, Santos I, Tellez M, Ortega E, Sanz J, Medrano L, Perez-Latorre L, Bellon J, Resino S, Bermejo J, Gonzalez-Garcia J, Gesida 3603b Study Grp. JAIDS-Journal of Acquired Immune Deficiency Syndromes. 2020 Mar 1;83(3):292-300. doi: 10.1097/QAI.0000000000002260. PMID: 31913996

Effects of HCV Eradication on Bone mineral density in HIV/HCV Coinfected Patients. Carrero, A, Berenguer J, Hontanon V, Guardiola JM, Navarro J, von Wichmann MA, Tellez MJ, Quereda C, Santos I, Sanz J, Galindo MJ, Hernandez Quero J, Jimenez Sousa MA, Perez Latorre L, Bellon JM, Resino S, Esteban H, Martinez E, Gonzalez Garcia J. Clinical Infectious Diseases. 2020 Sep 15;ciaa1396. doi: 10.1093/cid/ciaa1396. PMID: 32930720

Exosomes as Drug Delivery Systems: Endogenous Nanovehicles for Treatment of Systemic Lupus Erythematosus. Ortega A, Martinez-Arroyo O, Forner M, Cortes R. Pharmaceutics. 2020 Dec 22;13(1):E3. doi: 10.3390/pharmaceutics13010003. PMID: 3374908

Factors associated with the number of drugs in darunavir/cobicistat regimens. Martinez E, Negredo E, Knobel H, Ocampo A, Sanz J, Garcia-Fraile L, Martin-Carbonero L, Lozano F, Gonzalez-Domenech C, Gutierrez M, Montero M, Boix V, Payeras A, Torralba M, Gonzalez-Cordon A, Moreno A, Alejos B, Perez-Elias M, Galindo Puerto M, GeSIDA 9316 CODAR Study Grp. Journal of Antimicrobial Chemotherapy. 2020 Jan 1;75(1):208-214. doi: 10.1093/jac/dkz399. PMID: 31586414

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants. NCD Risk Factor Collaboration. Lancet. 2020 Nov 7;396(10261):1511-1524. doi: 10.1016/S0140-6736(20)31859-6. PMID: 33160572

How well are we performing the initial assessment of HIV-positive patients? Results from a multicentre cohort in Spain. Suarez-Garcia I, Alejos B, Delgado E, Rivero M, Pineda J, Jarrin I, Moreno S, del Amo J, Dalmau D, Navarro M, Gonzalez M, Blanco J, Garcia F, Rubio R, Iribarren J, Gutierrez F, Vidal F, Berenguer J, Gonzalez J, Jarrin I, Hernando V, Alejos B, Sanz N, Moreno C, Munoz-Fernandez M, Fernandez I, Fuentes J, Rico C, de la Fuente J, Concejo P, Azpilicueta E, Cohort Spanish HIV AIDS Network. HIV Medicine. 2020 Feb;21(2):128-134. doi: 10.1111/hiv.12817. PMID: 31702111

Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease. Borghi C, Agabiti-Rosei E, Johnson R, Kielstein J, Lurbe Ferrer E, Mancia G, Redón Mas J, Stack A, Tsioufis K. European Journal of Internal Medicine. 2020 Oct;80:1-11. doi: 10.1016/j.ejim.2020.07.006. PMID: 32739239

Identifying poor cardiorespiratory fitness in overweight and obese children and adolescents by using heart rate variability analysis under resting conditions. Redon Lurbe P, Grassi G, Redón Mas J, Alvarez Pitti J, Lurbe Ferrer E. Blood Pressure. 2020 Feb;29(1):13-20. doi: 10.1080/08037051.2019.1700777. PMID: 31829032

Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study. López Zumel M, Holgado Sánchez J, Ferrandez Izquierdo A, Saurí Ferrer M, Uso Talamantes R, Trillo Mata J, Vela Bernal S, Bea Serrano C, Nuñez Villota J, Ferrer Albero A, Gamez Payá J, Ruiz Hernandez A, Redón Mas J. Journal of Clinical Medicine. 2020 Jun 15;9(6):1869. doi: 10.3390/jcm9061869. PMID: 32549339

Impact of HIV on the survival of hepatocellular carcinoma in hepatitis C virus-infected patients. Merchante N, Rodriguez Fernandez M, Figueruela B, Rodriguez Arrondo F, Revollo B, Ibarra S, Tellez F, Merino E, Montero Alonso M, Galindo MJ, Rivero Juarez A, de Los Santos I, Delgado Fernandez M, Garcia Deltoro M, Vera Mendez FJ, Garcia MA, Aguirrebengoa K, Portu J, Rios Villegas MJ, Villalobos M, Aleman Valls MR, Minguez C, Galera C, Macias J, Pineda JA. AIDS. 2020 Aug 1;34(10):1497-1507. doi: 10.1097/QAD.0000000000002578. PMID: 32675563

Liver stiffness-based strategies predict absence of variceal bleeding in cirrhotic HCV-infected patients with and without HIV-coinfection after sustained virological response. Corma Gomez A, Macias J, Morano L, Rivero A, Tellez F, Rios MJ, Santos M, Serrano M, Palacios R, Merino D, Real LM, De Los Santos I, Vera Mendez FJ, Galindo MJ, Pineda JA. Clinical Infectious Diseases. 2020 Nov 19;ciaa1726. doi: 10.1093/cid/ciaa1726. PMID: 33211801

Magnetic Resonance imaging analysis of liver fibrosis and inflammation: overwhelming gray zones restrict clinical use. Marti Aguado D, Rodriguez-Ortega A, Alberich-Bayarri A, Marti-Bonmati L. Abdominal Radiology. 2020 Nov;45(11):3557-3568. doi: 10.1007/s00261-020-02713-1. PMID: 32857259

Maintenance of virologic suppression and improvement in comorbidities after simplification to raltegravir plus boosted darunavir among treatment-experienced HIV-infected patients. Casado J, Vizcarra P, Blanco J, Montejano R, Negredo E, Espinosa N, Montero M, Mena A, Palacios R, Lopez J, Vergas J, Galindo Puerto M, Cabello A, Garcia Deltoro M, Diaz De Santiago A, BIRDi Study Grp. International Journal of STD & AIDS. 2020 Apr;31(5):467-473. doi: 10.1177/0956462419896478. PMID: 32138618

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries. NCD Risk Factor Collaboration. International Journal of Epidemiology. 2020 Feb 1;49(1):173-192. doi: 10.1093/ije/dyz099. PMID: 31321439

Nutraceuticals and blood pressure control: a European Society of Hypertension position document. Borghi C, Tsioufis K, Agabiti-Rosei E, Burnier M, Cicero A, Clement D, Coca A, Desideri G, Grassi G, Lovic D, LURBE FERRER E, Kahan T, Kreutz R, Jelakovic B, Polonia J, Redón Mas J, Van De Borne P, Mancia G. Journal of Hypertension. 2020 May;38(5):799-812. doi: 10.1097/HJH.0000000000002353. PMID: 31977574

Optimization of small RNA library preparation protocol from human urinary exosomes. Olivares Gazquez M, Perez Hernandez J, Perez Gil D, Chaves Martínez F, Redón Mas J, Cortés Vergaz R. Journal of Translational Medicine. 2020 Mar 18;18(1):132. doi: 10.1186/s12967-020-02298-9. PMID: 32188466

p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to NNRTI. Gruevska A, Moragrega A, Galindo Puerto M, Esplugues Mota J, Blas García A, Apostolova N. Antiviral Research. 2020 Jun;178:104784. doi: 10.1016/j.antiviral.2020.104784. PMID: 32272174

Pulmonary thrombosis in situ’: risk factors, clinic characteristics and long-term evolution. Fletcher-Sanfeliu D, Redon J, Garcia-Granero A, Frasson M, Barreira I, Martinez-Leon J, Garcia-Fuster M. Blood Coagulation & Fibrinolysis. 2020 Oct;31(7):469-475. doi: 10.1097/MBC.0000000000000949. PMID: 32833808

Rab-rabphilin system in injured human podocytes stressed by glucose overload and angiotensin II. Martínez Arroyo O, Ortega Gutiérrez A, Perez Hernandez J, Chaves Martínez F, Redón Mas J, Cortés Vergaz R. American Journal of Physiology. Renal Physiology. 2020 Aug 1;319(2):F178-F191. doi: 10.1152/ajprenal.00077.2020. PMID: 32567349

Rabphilin involvement in filtration and molecular uptake in Drosophila nephrocytes suggests a similar role in human podocytes. Selma Soriano E, Llamusi Troisi M, Fernandez Costa J, Ozimski L, Artero Allepuz R, Redón Mas J. Disease Models & Mechanisms. 2020 Jun 15;170:108030. doi: 10.1016/j.neuropharm.2020.108030. PMID: 32680845

Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients. Iborra M, Garcia-Morales N, Rubio S, Bertoletti F, Calvo M, Taxonera C, Bosca Watts M, Sierra M, Mancenido N, Beltran B, Castillejo O, Garcia-Planella E, Vera I, Alba C, Marti Aguado D, Ballester Ferre M, Cano-Sanz N, Pajares-Villarroya R, Cerrillo E, Canada A, Nos P. Scientific Reports. 2020 Oct 20;10(1):17774. doi: 10.1038/s41598-020-73577-0. PMID: 33082359

Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513

Repositioning of the global epicentre of non-optimal cholesterol. NCD Risk Factor Collaboration (NCD-RisC). Nature. 2020 Jun;582(7810):73-77. doi: 10.1038/s41586-020-2338-1. PMID: 32494083

Resting heart rate and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk analysis from the ONTARGET/TRANSCEND trials.Böhm M, Schumacher H, Teo K, Lonn E, Mahfoud F, Ukena C, Mann J, Mancia G, Redón Mas J, Schmieder R, Sliwa K, Marx N, Weber M, Williams B, Yusuf S. European Heart Journal. 2020 Jan 7;41(2):231-238. doi: 10.1093/eurheartj/ehy808. PMID: 30590564

Risk, Diagnostic and Predictor Factors for Classical Hodgkin Lymphoma in HIV-1-Infected Individuals: Role of Plasma Exosome-Derived miR-20a and miR-21. Hernandez-Walias F, Vazquez E, Pacheco Y, Rodriguez-Fernandez J, Perez-Elias M, Dronda F, Casado J, Moreno A, Hermida J, Quereda C, Hernando A, Tejerina-Picado F, Asensi V, Galindo Puerto M, Leal M, Moreno S, Vallejo A. Journal of Clinical Medicine. 2020 Mar 11;9(3):760. doi: 10.3390/jcm9030760. PMID: 32168859

Similar Clinical Course and Significance of Circulating Innate and Adaptive Immune Cell Counts in STEMI and COVID-19. de Dios E, Rios-Navarro C, Perez-Sole N, Gavara J, Marcos-Garces V, Rodríguez E, Carratalá A, Forner MJ, Navarro J, Blasco ML, Bondia E, Signes-Costa J, Vila JM, Forteza MJ, Chorro 1MJ, Bodi V. Journal of Clinical Medicine. 2020 Oct 28;9(11):E3484. doi: 10.3390/jcm9113484. PMID: 33126723

The influence of hemoglobin A1c levels on cardiovascular events and all-cause mortality in people with diabetes over 70 years of age. A prospective study. Orozco-Beltran D, Navarro Perez J, Cebrian-Cuenca A, Alvarez-Guisasola F, Caride-Miana E, Mora G, Quesada J, Lopez-Pineda A, Cardona-Llorens A, Redón Mas J, Gil-Guillen V, Ferrandez Izquierdo A, Carratala-Munuera C. Primary Care Diabetes. 2020 Dec;14(6):678-684. doi: 10.1016/j.pcd.2020.06.003. PMID: 32605878

Unraveling new factors associated with hypertension: the Mendelian randomization approach. Grau Pérez M, Redón Mas J. Journal of Hypertension. 2020 Jan;38(1):30-32. doi: 10.1097/HJH.0000000000002251. PMID: 31790017

Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology. Piepoli M, Abreu A, Albus C, Ambrosetti M, Brotons C, Catapano A, Corra U, Cosyns B, Deaton C, Graham I, Hoes A, Lochen M, Matrone B, Redón Mas J, Sattar N, Smulders Y, Tiberi M. European Journal of Preventive Cardiology. 2020 Jan;27(2):181-205. doi: 10.1177/2047487319893035. PMID: 31826679

Urinary exosomal miR-146a as a marker of albuminuria, activity changes and disease flares in lupus nephritis. Perez Hernandez J, Martínez Arroyo O, Ortega Gutiérrez A, Galera Martos M, Solis Salguero M, Chaves Martínez F, Redón Mas J, Forner Giner M, Cortés Vergaz R. Journal Of Nephrology. 2020 Aug 16. doi: 10.1007/s40620-020-00832-y. PMID: 32803682

Visit-to-visit blood pressure variability and renal outcomes: results from ONTARGET and TRANSCEND trials. Mancia G, Schumacher H, Bohm M, Mann J, Redón Mas J, Facchetti R, Schmieder R, Lonn E, Teo K, Yusuf S. Journal of Hypertension. 2020 Oct;38(10):2050-2058. doi: 10.1097/HJH.0000000000002567. PMID: 32694337

Week 48 Resistance Analyses of the Once-Daily, Single-Tablet Regimen Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) in Adults Living with HIV-1 from the Phase III Randomized AMBER and EMERALD Trials. Lathouwers E, Wong E, Brown K, et al. AIDS Research and Human Retroviruses. 2020 Jan;36(1):48-57. doi: 10.1089/AID.2019.0111. PMID: 31516033

2018 ESC/ESH Guidelines for the management of arterial. Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I. Kardiologia Polska. 2019;77(2):71-159. doi: 10.5603/KP.2019.0018. PMID: 30816983

Association of Arsenic Exposure With Cardiac Geometry and Left Ventricular Function in Young Adults. Pichler G, Grau-Perez M, Tellez-Plaza M, Umans J, Best L, Cole S, Goessler W, Francesconi K, Newman J, Redon J, Devereux R, Navas-Acien A. Circulation. Cardiovascular imaging. 2019 May;12(5):e009018. doi: 10.1161/CIRCIMAGING.119.009018. PMID: 31060373

Cardiovascular outcomes and achieved blood pressure in patients with and without diabetes at high cardiovascular risk. Böhm M, Schumacher H, Teo KK, Lonn EM, Mahfoud F, Mann JFE, Mancia G, Redon J, Schmieder RE, Marx N, Sliwa K, Weber MA, Williams B, Yusuf S. European Heart Journal. 2019 Jul 1;40(25):2032-2043. doi: 10.1093/eurheartj/ehz149. PMID: 30919899

Circular RNAS: novel biomarkers of disease activity in systemic lupus erythematosus?. Cortes R, Forner MJ. Clinical Science. 2019 May 7;133(9):1049-1052. doi: 10.1042/CS20180826. PMID: 31064795

Cohort profile: the Hortega Study for the evaluation of non-traditional risk factors of cardiometabolic and other chronic diseases in a general population from Spain. Tellez-Plaza M, Briongos-Figuero L, Pichler G2, Dominguez-Lucas A, Simal-Blanco F, Mena-Martin FJ, Bellido-Casado J, Arzua-Mouronte D, Chaves FJ, Redon J, Martin-Escudero JC. BMJ Open. 2019 Jun 27;9(6):e024073. doi: 10.1136/bmjopen-2018-024073. PMID: 31248913

Diastolic left ventricular function in relation to circulating metabolic biomarkers in a population study. Zhang ZY, Marrachelli VG, Yang WY, Trenson S, Huang QF, Wei FF, Thijs L, Van Keer J, Monleon D, Verhamme P, Voigt JU, Kuznetsova T, Redón J, Staessen JA. European Journal of Preventive Cardiology. 2019 Jan;26(1):22-32. doi: 10.1177/2047487318797395. PMID: 30196724

Effectiveness and safety of dual therapy with rilpivirine and boosted darunavir in treatment-experienced patients with advanced HIV infection: a preliminary 24week analysis (RIDAR study). Pasquau J, de Jesus SE, Arazo P, Crusells MJ, Ríos MJ, Lozano F, de la Torre J, Galindo MJ, Carmena J, Santos J, Tornero C, Verdejo G, Samperiz G, Palacios Z, Hidalgo-Tenorio C; RIDAR Study Group. BMC Infectious Diseases. 2019 Feb 28;19(1):207. doi: 10.1186/s12879-019-3817-6. PMID: 30819101

Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA). Jones MR, Tellez-Plaza M, Vaidya D, Grau-Perez M, Post WS, Kaufman JD, Guallar E, Francesconi KA, Goessler W, Nachman KE, Sanchez TR, Navas-Acien A. Journal of Exposure Science and Environmental Epidemiology. 2019 Apr;29(3):310-322. doi: 10.1038/s41370-018-0042-0. PMID: 29795237

Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2018). AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan. Enfermedades Infecciosas y Microbiologia Clinica. 2019 Mar;37(3):195-202. doi: 10.1016/j.eimc.2018.02.010. PMID: 29759422

Gender-related differences in serum uric acid in treated hypertensive patients from central and east European countries: findings from the Blood Pressure control rate and CArdiovascular Risk profilE study. Redon P, Maloberti A, Facchetti R, Redon J, Lurbe E, Bombelli M, Mancia G, Grassi G. Journal of Hypertension. 2019 Feb;37(2):380-388. doi: 10.1097/HJH.0000000000001908. PMID: 30074564

Health-related quality of life in patients with systemic lupus erythematosus: a Spanish study based on patient reports. Román Ivorra JA, Fernández-Llanio-Comella N, San-Martín-Álvarez A, Vela-Casasempere P, Saurí-Ferrer I, González-de-Julián S, Vivas-Consuelo D. Clinical Rheumatology. 2019 Jul;38(7):1857-1864. doi: 10.1007/s10067-019-04485-6. PMID: 30820696

Healthcare Experience and their Relationship with Demographic, Disease and Healthcare-Related Variables: A Cross-Sectional Survey of Patients with Chronic Diseases Using the IEXPAC Scale. Orozco-Beltrán D, de Toro J, Galindo MJ, Marín-Jiménez I, Casellas F, Fuster-RuizdeApodaca MJ, García-Vivar ML, Hormigo-Pozo A, Guilabert M, Sánchez-Vega N, Fernández G, Cea-Calvo L. Patient-Patient Centered Outcomes Research. 2019 Jun;12(3):307-317. doi: 10.1007/s40271-018-0345-1. PMID: 30430456

Immigration and hypertension in youths learning from one country’s experience. Lurbe E, Redon J. Journal of Hypertension. 2019 Apr;37(4):680-682. doi: 10.1097/HJH.0000000000002028. PMID: 30817446

Immune-unreactive urinary albumin as a predictor of cardiovascular events: the Hortega Study. Martínez F, Pichler G, Ruiz A, Martín-Escudero JC, Chaves FJ, Gonzalez-Albert V, Tellez-Plaza M, Heerspink HJL, Zeeuw DDE, Redon J. Nephrology Dialysis Transplantation. 2019 Apr 1;34(4):633-641. doi: 10.1093/ndt/gfy087. PMID: 29788140

Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. Lurbe E, Torró I, Álvarez J, Aguilar F, Mancia G, Redon J, Redon P. Journal of Hypertension. 2019 Dec;37(12):2414-2421. doi: 10.1097/HJH.0000000000002229. PMID: 31688292

Losses to follow-up of HIV-infected people in the Spanish VACH cohort over the period between 2013 and 2014: The importance of sociodemographic factors. Teira R, Espinosa N, Gutiérrez MM, Montero M, Martínez E, González F, Lozano de León F, Téllez F, Galindo MJ, Peraire J, Deig E, Muñoz-Sánchez P; para el Grupo de estudio VACH. Enfermedades Infecciosas y Microbiologia Clinica. 2019 Jun-Jul;37(6):361-366. doi: 10.1016/j.eimc.2018.09.008. PMID: 30514587

Low performance of ultrasound surveillance for the diagnosis of hepatocellular carcinoma in HIV-infected patients. Merchante N, Figueruela B, Rodríguez-Fernández M, Rodríguez-Arrondo F, Revollo B, Ibarra S, Galindo MJ, Merino E, Montero M, Téllez F, García-Deltoro M, Rivero-Juárez A, Delgado-Fernández M, Ríos-Villegas MJ, Aguirrebengoa K, García MA, Portu J, Vera-Méndez FJ, Villalobos M, Mínguez C, De Los Santos I, López-Ruz MA, Omar M, Galera C, Macias J, Pineda JA; GEHEP-002 Study Group. AIDS. 2019 Feb 1;33(2):269-278. doi: 10.1097/QAD.0000000000002065. PMID: 30325782

May Measurement Month 2017: an analysis of blood pressure screening in Spain-Europe. Molinero A, Ruilope LM, Tous S, Fornos JA, Mera I, Andrés NF, Iracheta M, Xia X, Beaney T, Poulter NR, Rodilla E, Martínez F, Gijón-Conde T. European Heart Journal Supplements. 2019 Apr;21(Suppl D):D107-D110. doi: 10.1093/eurheartj/suz070. PMID: 31043894

Number of drugs used in secondary cardiovascular prevention and late survival in the population of Valencia Community, Spain. Redón J, Usó R, Trillo JL, López C, Morales-Olivas F, Navarro J, Sanchís J, Gil V, Orozco-Beltrán D. International Journal of Cardiology. 2019 Oct 15;293:260-265. doi: 10.1016/j.ijcard.2019.05.071. PMID: 31229263

Outcome of an HIV education program for primary care providers: Screening and late diagnosis rates. Martínez Sanz J, Pérez Elías MJ, Muriel A, Gómez Ayerbe C, Vivancos Gallego MJ, Sánchez Conde M, Herrero Delgado M, Pérez Elías P, Polo Benito L, de la Fuente Cortés Y, Barea R, Sullivan AK, Fuster Ruiz de Apodaca MJ, Galindo MJ, Moreno S; DRIVE 03, OPTtest WP5 and FOCO Study Groups. PLoS One. 2019 Jul 2;14(7):e0218380. doi: 10.1371/journal.pone.0218380. PMID: 31265464

Outcomes by sex following treatment initiation with darunavir/cobicistat in a large Spanish cohort of the CODAR study (GeSIDA 9316) (vol 74, pg 3044, 2019). Pérez Elías MJ, Alejos B, Vivancos MJ, Ribera E, Galindo MJ, Vilanova-Trillo L, García-Fraile Fraile LJ, de La Fuente Moral S, Garcia De Lomas J, Lozano F, Mateo García MG, Tasias Pitarch M, Diez Martinez M, Rojas J, Raya-Cruz M, Sepúlveda MA, Troya J, Del Campo S, Martinez E. Journal of Antimicrobial Chemotherapy. 2019 Oct 1;74(10):3124. doi: 10.1093/jac/dkz331. PMID: 31377772

Outcomes by sex following treatment initiation with darunavir/cobicistat in a large Spanish cohort of the CODAR study (GeSIDA 9316). Pérez Elías MJ, Alejos B, Vivancos MJ, Ribera E, Galindo MJ, Vilanova-Trillo L, García-Fraile Fraile LJ, de La Fuente Moral S, Garcia De Lomas J, Lozano F, Mateo García MG, Tasias Pitarch M, Diez Martinez M, Rojas J, Raya-Cruz M, Sepúlveda MA, Troya J, Del Campo S, Martinez E; CODAR study group. Journal of Antimicrobial Chemotherapy. 2019 Oct 1;74(10):3044-3048. doi: 10.1093/jac/dkz254. PMID: 31236601

Prevalence and patterns of illicit drug use in people living with HIV in Spain: A cross-sectional study. Fuster-RuizdeApodaca MJ, Castro-Granell V, Garin N, Laguía A, Jaén Á, Iniesta C, Cenoz S, Galindo MJ. PLoS One. 2019 Jun 17;14(6):e0211252. doi: 10.1371/journal.pone.0211252. PMID: 31206550

Rising rural body-mass index is the main driver of the global obesity epidemic in adults. NCD Risk Factor Collaboration (NCD-RisC). Nature. 2019 May;569(7755):260-264. doi: 10.1038/s41586-019-1171-x. PMID: 31068725

Targeted metabolomics to understand the association between arsenic metabolism and diabetes-related outcomes: Preliminary evidence from the Strong Heart Family Study. Spratlen MJ, Grau-Perez M, Umans JG, Yracheta J, Best LG, Francesconi K, Goessler W, Bottiglieri T, Gamble MV, Cole SA, Zhao J, Navas-Acien A. Environmental Research. 2019 Jan;168:146-157. doi: 10.1016/j.envres.2018.09.034. PMID: 30316100

The association of urine metals and metal mixtures with cardiovascular incidence in an adult population from Spain: the Hortega Follow-Up Study. Domingo-Relloso A, Grau-Perez M, Briongos-Figuero L, Gomez-Ariza JL, Garcia-Barrera T, Dueñas-Laita A, Bobb JF, Chaves FJ, Kioumourtzoglou MA, Navas-Acien A, Redon-Mas J, Martin-Escudero JC, Tellez-Plaza M. International Journal of Epidemiology. 2019 Dec 1;48(6):1839-1849. doi: 10.1093/ije/dyz061. PMID: 31329884

The experience of inflammatory bowel disease patients with healthcare A survey with the IEXPAC instrument. Marín-Jiménez I, Casellas F, Cortés X, García-Sepulcre MF, Juliá B, Cea-Calvo L, Soto N, Navarro-Correal E, Saldaña R, de Toro J, Galindo MJ, Orozco-Beltrán D. Medicine. 2019 Apr;98(14):e15044. doi: 10.1097/MD.0000000000015044. PMID: 30946348

The Influence of Patient Experience with Healthcare on the Health-Related Quality of Life of People Living with HIV: An Observational Cross-Sectional Survey. Fuster-RuizdeApodaca M, Sanchez-Vega N, Galindo Puerto M, Marin-Jimenez I, de Toro J, Orozco-Beltran D, Cotarelo M, Carlos Lopez J. Infectious Diseases and Therapy. 2019 Sep;8(3):369-382. doi: 10.1007/s40121-019-0252-3. PMID: 31290081

Urinary metals and leukocyte telomere length in American Indian communities: The Strong Heart and the Strong Heart Family Study. Grau-Perez M, Zhao J, Pierce B, Francesconi KA, Goessler W, Zhu Y, An Q, Umans J, Best L, Cole SA, Navas-Acien A, Tellez-Plaza M. Environmental Pollution. 2019 Mar;246:311-318. doi: 10.1016/j.envpol.2018.12.010. PMID: 30557805

Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study. Domingo-Relloso A, Grau-Perez M, Galan-Chilet I, Garrido-Martinez MJ, Tormos C, Navas-Acien A, Gomez-Ariza JL, Monzo-Beltran L, Saez-Tormo G, Garcia-Barrera T, Dueñas Laita A, Briongos Figuero LS, Martin-Escudero JC, Chaves FJ, Redon J, Tellez-Plaza M. Environment International. 2019 Feb;123:171-180. doi: 10.1016/j.envint.2018.11.055. PMID: 30529889

Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1. Eron JJ, Orkin C, Cunningham D, Pulido F, Post FA, De Wit S, Lathouwers E, Hufkens V, Jezorwski J, Petrovic R, Brown K, Van Landuyt E, Opsomer M; EMERALD study group. Antiviral Research. 2019 Oct;170:104543. doi: 10.1016/j.antiviral.2019.104543. PMID: 31279073

Proyectos
Referencia: WELLBASED
Título: WELLBASED aims at designing, implementing and evaluating a comprehensive urban programme to significantly reduce energy poverty and its effects on the
Entidad Financiadora: European Commission
Investigador principal: Josep Redón i Mas
Duración: 2021 – 2024
Presupuesto:

Referencia: PI19/01796
Título: Implicaciones experimentales y clinicas del complejo proteico rabphilin-rab en daño renal en la diabetes mellitus tipo 2
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Josep Redón i Mas
Duración: 2020 – 2022
Presupuesto: 196.020 €

Referencia: PI18/01405
Título: Perfil de microRNAs exosomales y su valor pronostico a largo plazo en el lupus eritematoso sistemico. Asociacion con marcadores establecidos de daño renal
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Raquel Cortés Vergaz
Duración: 2019 – 2021
Presupuesto: 111.320 €

Referencia: BigMedilytics
Título: Big Data for Medical Analytics
Entidad Financiadora: European Commission
Investigador principal: Josep Redón i Mas
Duración: 2018 – 2021
Presupuesto: 1.062.136 €

Referencia: BodyPass
Título: API-ecosystem for cross-sectorial exchange of 3D personal data
Entidad Financiadora: European Commission
Investigador principal: Josep Redón i Mas
Duración: 2018 – 2021
Presupuesto: 351.938 €

Referencia: PT17/0005/0017
Título: Innovation Platform
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Josep Redón i Mas
Duración: 2018 – 2021
Presupuesto: 38.985 €

Referencia: BigData@Heart
Título: Big Data for Better Hearts
Entidad Financiadora: European Commission
Investigador principal: Josep Redón i Mas
Duración: 2017 – 2022
Presupuesto: 386.250 €

Referencia: ADVANTAGE
Título: Managing Frailty. A comprehensive approach to promote a disability-free advanced age in Europe: the ADVANTAGE initiative
Entidad Financiadora: European Commission (3rd Health Program)
Investigador principal: Josep Redón i Mas, José Viña Ribes
Duración: 2016 – 2020
Presupuesto: 130.005 €

+ Información
Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513

2018 ESC/ESH Guidelines for the management of arterial. Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I. Kardiologia Polska. 2019;77(2):71-159. doi: 10.5603/KP.2019.0018. PMID: 30816983

Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. Lurbe E, Torró I, Álvarez J, Aguilar F, Mancia G, Redon J, Redon P. Journal of Hypertension. 2019 Dec;37(12):2414-2421. doi: 10.1097/HJH.0000000000002229. PMID: 31688292

Título: Sistema de biosensado fotónico para la detección de trombina, alérgenos y patógenos. Funcionalización química de chips fotónicos basados en estructuras de anillos resonantes
Doctorando: Sánchez Sánchez, Carlos
Director: Martí Sendra, Javier; Redón Mas, Josep; Peransí Llopis, Sergio Manuel
Fecha: 15/11/2019
Universidad: Universitat Politècnica de València

Título: Valor pronóstico de los cambios en la rigidez arterial en la hipertensión arterial esencial
Doctorando: Calaforra Juan, Oscar
Director: Redón Mas, Josep; Forner Giner, María José; Martínez García, Fernando
Fecha: 28/07/2020
Universidad: Universitat de València

Título: Estudio de la evolución del sellado distal ilíaco en el tratamiento endovascular de la aorta abdominal
Doctorando: Bargay Juan, Pau
Director: Redon Mas, Josep; Plaza Martínez, Ángel
Fecha: 25/02/2019
Universidad: Universitat de València