Grupo de Investigación en Autonomía Personal, Dependencia y Trastornos Mentales Graves

Área de Metabolismo y Daño Orgánico


El grupo Grupo de Investigación en Autonomía Personal, Dependencia y Trastornos Mentales Graves desde su constitución en 2001 ha trabajado en contribuir al conocimiento de los déficit cognitivos y funcionales de enfermedades como la esquizofrenia y el trastorno bipolar, y la identificación de endofenotipos y biomarcadores relacionados con dicho deterioro. Más recientemente desde las perspectivas transdiagnóstica y comórbida/multimorbida se incluyen comparativas con otro tipo de enfermedades que cursan con deterioro cognitivo y funcional como la Diabetes Mellitus, la Encefalopatía Hepática o el Cáncer. Desde su consolidación en 2007 es un «Grupo de Excelencia PROMETEO FASE II» de la GVA, y en 2009 se establece como G24 del Centro de Investigaciones Biomédicas En Red para Salud Mental (CIBERSAM-ISCIII). En 2013 comienza a ser parte del Programa European Innovation Partnership on Active and Healthy Ageing (Acción 3) Cognitive Decline Group of the European Innovation Partnership for Active and Healthy Ageing (EIPAHA), participando activamente en definir una posición clínicamente útil sobre el «Mild Cognitive Decline».

Este grupo dirige y coordina la Unidad de Evaluación en Autonomía Personal, Dependencia y Trastornos Mentales (TMAP) ubicada en la Facultat de Medicina UCIM-INCLIVA, con una oferta de servicios en valoraciones biomecánicas y evaluaciones neurocognitivas que se enmarca en la prevención de los signos de fragilidad en poblaciones de riesgo. La Unidad TMAP es pionera en la realización e implantación de evaluaciones a pacientes con trastornos mentales y/o con deterioro cognitivo y funcional de una forma integral y personalizada. Estas evaluaciones son necesarias para valorar cómo las personas lidian con las actividades diarias en una situación de enfermedad o deterioro, y para proveerles de información con el fin de aplicar medidas que puedan facilitar una vida sana e independiente. La unidad cuenta con una tecnología de apoyo clínico que permite objetivar parámetros que tradicionalmente se obtenían de forma subjetiva.


Dr. Rafael Tabarés Seisdedos
Coordinador
Dr. Rafael Tabarés Seisdedos
rafael.tabares@uv.es

INVESTIGADORES
R4 Senior

Rafael Tabarés Seisdedos    
Vicente Balanzá Martínez
Manuel Gómez Beneyto

R3 Consolidado

Gabriel Selva Vera
Inmaculada Fuentes Durá
Jose Salazar Fraile
Manuel Girón Giménez
Patricia Correa Ghisays

R2 Novel / Emergente

Constanza San Martín Valenzuela
Diego Macías Saint-Gerons
Jaume Forés Martos
Pau Soldevila Matías

R1 Predoctoral

Joan Vicent Sánchez Ortí

STAFF
Colaborador/a
Enfermero/a
Técnico/a
Apoyo
Publicaciones
A cross-sectional analysis identified co-authorship networks and scientific collaboration on reporting guidelines for health research. Catala Lopez F, Alonso Arroyo A, Page MJ, Castello Cogollos L, Hutton B, Ridao M, Tabares Seisdedos R, Aleixandre Benavent R, Moher D. Journal of Clinical Epidemiology. 2023 Feb 22;157:22-34. doi: 10.1016/j.jclinepi.2023.02.001. PMID: 36822440

Barriers of access to opioid medicines within the context of palliative care in Latin America: the perception of health professionals. Vahos J, Rojas-Cortes R, Daza D, Osorio-Florez LC, Macias Saint-Gerons D, Pastrana T, Munoz S, Fitzgerald J, Porras A, Luciani S, Castro JL. Journal of Palliative Medicine. 2023 Feb;26(2):199-209. doi: 10.1089/jpm.2022.0122. PMID: 36040320

Computer-aided drug repurposing to tackle antibiotic resistance based on topological data analysis. Tarin-Pello A, Suay-Garcia B, Fores-Martos J, Falco A, Perez-Gracia M. Computers In Biology and Medicine. 2023 Sep 28:166:107496. doi: 10.1016/j.compbiomed.2023.107496. PMID: 37793206

Evaluating the online impact of reporting guidelines for randomised trial reports and protocols: a cross-sectional web-based data analysis of CONSORT and SPIRIT initiatives. Orduna-Malea E, Alonso-Arroyo A, Ontalba-Ruiperez J, Catala-Lopez F. Scientometrics. 2023;128(1):407-440. doi: 10.1007/s11192-022-04542-z. PMID: 36274792

Functional balance training in people with Parkinson’s disease: a protocol of balanceHOME randomized control trial with crossover. Guinot S, Valenzuela C, Asensi V, Anton C, Navarro M, Tomas J. Frontiers in Aging Neuroscience. 2023 Apr 26;15:1137360. doi: 10.3389/fnagi.2023.1137360. PMID: 37266404

Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026. Global Burden of Disease 2021 Health Financing Collaborator Network. Lancet. Global Health. 2023 Mar;11(3):e385-e413. doi: 10.1016/S2214-109X(23)00007-4. PMID: 36706770

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021. GBD 2021 Diabetes Collaborators. Lancet. 2023 Jul 15;402(10397):203-234. doi: 10.1016/S0140-6736(23)01301-6. PMID: 37356446

Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019. Wu D, Jin Y, Xing Y, et al. Eclinicalmedicine. 2023 Sep 9:64:102193. doi: 10.1016/j.eclinm.2023.102193. PMID: 37731935

Hepatitis B and C in Europe: an update from the Global Burden of Disease Study 2019. GBD 2019 Europe Hepatitis B & C Collaborators. Lancet. Public Health. 2023 Sep;8(9):e701-e716. doi: 10.1016/S2468-2667(23)00149-4. PMID: 37633679

Impact of traumatic life events on clinical variables of individuals with first-episode psychosis and healthy controls. Butjosa A, Usall J, Vila-Badia R, Mezquida G, Cuesta M, Rodriguez-Toscano E, Amoretti S, Lobo A, Gonzalez-Pinto A, Espliego A, Corripio I, Vieta E, Baeza I, Berge D, Bernardo M. International Journal of Social Psychiatry. 2023 Feb;69(1):134-145. doi: 10.1177/00207640211070398. PMID: 35068217

In pursuit of full recovery in major depressive disorder. Vicent-Gil M, Serra-Blasco M, Navarra-Ventura G, Trujols J, Balanza-Martinez V, Portella M, Cardoner N. European Archives of Psychiatry and Clinical Neuroscience. 2023 Aug;273(5):1095-1104. doi: 10.1007/s00406-022-01487-5. PMID: 36085532

Inflammation and lipid metabolism as potential biomarkers of memory impairment across type 2 diabetes mellitus and severe mental disorders. Sanchez-Orti J, Correa-Ghisays P, Balanza-Martinez V, Selva-Vera G, Vila-Frances J, Magdalena-Benedito R, San-Martin C, Victor V, Escribano-Lopez I, Hernandez-Mijares A, Vivas-Lalinde J, Crespo-Facorro B, Tabares-Seisdedos R. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2023 Jun 15;127:110817. doi: 10.1016/j.pnpbp.2023.110817. PMID: 37327846

Lifestyle changes during the COVID-19 pandemic in Brazil: results from three consecutive cross-sectional web surveys. Ribeiro-Alves M, Costa G, da Mota J, Cardoso T, Cerezer K, Martini T, de Sousa M, Bastos F, Balanzá-Martínez V, Kapczinski F, De Boni R. BMJ Open. 2023 Jul 9;13(7):e070328. doi: 10.1136/bmjopen-2022-070328. PMID: 37423635

Lifestyle interventions for bipolar disorders: a systematic review and meta-analysis. Simjanoski M, Patel S, Boni R, Balanza-Martinez V, Frey B, Minuzzi L, Kapczinski F, Cardoso T. Neuroscience and Biobehavioral Reviews. 2023 May 30;152:105257. doi: 10.1016/j.neubiorev.2023.105257. PMID: 37263531

miR-146a-5p promotes angiogenesis and confers trastuzumab resistance in HER2+ breast cancer. Cabello P, Torres-Ruiz S, Adam-Artigues A, Fores-Martos J, Martinez M, Hernando C, Zazo S, Madoz-Gurpide J, Rovira A, Burgues O, Rojo F, Albanell J, Lluch A, Bermejo B, Cejalvo J, Eroles P. Cancers. 2023 Apr 4;15(7):2138. doi: 10.3390/cancers15072138. PMID: 37046799

Myopericarditis associated with the novavax COVID-19 Vaccine (NVX-CoV2373): a retrospective analysis of individual case safety reports from VigiBase. Macias Saint-Gerons D, Ibarz M, Castro J, Fores-Martos J, Tabares-Seisdedos R. Drugs – Real World Outcomes. 2023 Jun;10(2):263-270. doi: 10.1007/s40801-023-00355-5. PMID: 36788170

Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?. Baeza I, de la Serna E, Mezquida G, Cuesta M, Vieta E, Amoretti S, Lobo A, Gonzalez-Pinto A, Diaz-Caneja C, Corripio I, Valli I, Puig O, Mane A, Bioque M, Ayora M, Bernardo M, Castro-Fornieles J, Balanza Martinez V, PEPs Grp. European Child & Adolescent Psychiatry. 2023 Apr 7. doi: 10.1007/s00787-023-02196-7. PMID: 37027026

Spanish validation of the Empirically Developed Clinical Staging Model (EmDe-5) for patients with bipolar disorder. De la Fuente-Tomas L, Arranz B, Sierra P, Sanchez-Autet M, Garcia-Blanco A, Gutierrez-Rojas L, Balanza-Martinez V, Vidal-Rubio S, Vieta E, Jimenez E, Hernandez C, Arrojo M, Gomez-Trigo J, Zapico-Merayo Y, Pelayo-Teran J, Perez-Sola V, Mur E, Cardoner N, Gonzalez-Pinto A, Zorrilla I, Ruiz-Veguilla M, Catalan-Barragan R, Safont G, Martinez-Cao C, Saiz P, Bobes J, Garcia-Portilla M. Revista de Psiquiatria y Salud Mental. 2023 Sep 26:S1888-9891(21)00104-X. doi: 10.1016/j.rpsm.2021.09.005. PMID: 37965877

Transparency, openness and reproducible research practices are frequently underused in health economic evaluations. Catala-Lopez F, Ridao M, Tejedor-Romero L, Caulley L, Hutton B, Husereau D, Alonso-Arroyo A, Bernal-Delgado E, Drummond M, Moher D. Journal of Clinical Epidemiology. 2023 Nov 6:S0895-4356(23)00292-5. doi: 10.1016/j.jclinepi.2023.10.024. PMID: 37939742

Tumour necrosis factor (TNF) antagonist therapy for paediatric inflammatory bowel disease: a systematic review. Martín-García P, Alonso-Arroyo A, Catalá-López F. Medicina Clinica. 2023 Jun 9;160(11):501-516. doi: 10.1016/j.medcli.2023.02.006. PMID: 36967304

Women’s Involvement in Steady Exercise (WISE): study protocol for a randomized controlled trial. Ferrando-Terradez I, Duenas L, Parcina I, Copic N, Petronijevic S, Beltrami G, Pezzoni F, San Martin-Valenzuela C, Gijssel M, Moliterni S, Papageorgiou P, Rodriguez-Carrasco Y. Healthcare. 2023 Apr 29;11(9):1279. doi: 10.3390/healthcare11091279. PMID: 37174821

A cofactor-based mechanism for the origin of the genetic code. Martinez Gimenez J, Tabares Seisdedos R. Origins of Life and Evolution of Biospheres. 2022 Sep;52(1-3):149-163. doi: 10.1007/s11084-022-09628-5. PMID: 36071304

A GBD 2019 study of health and sustainable development goal gains and forecasts to 2030 in Spain. Lazarus J, Ortiz A, Tyrovolas S, Fernandez E, Guy D, White T, Ma R, Hay S, Naghavi M, Soriano J. Scientific Reports. 2022 Dec 7;12(1):21154. doi: 10.1038/s41598-022-24719-z. PMID: 36477107

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019. Peden A, Cullen P, Francis K, et al. Lancet Public Health. 2022 Aug;7(8):e657-e669. doi: 10.1016/S2468-2667(22)00134-7. PMID: 35779567

Assessing performance of the healthcare access and quality index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Haakenstad A, Yearwood J, Fullman N, et al. Lancet. Global Health. 2022 Dec;10(12):e1715-e1743. doi: 10.1016/S2214-109X(22)00429-6. PMID: 36209761

Brain activity changes with emotional words in different stages of psychosis. Soldevila-Matias P, Garcia-Marti G, Fuentes-Dura I, Ruiz JC, Gonzalez-Navarro L, Gonzalez-Vivas C, Radua J, Sanjuan J. European Psychiatry. 2022 Oct 4;66(1):e25. doi: 10.1192/j.eurpsy.2022.2321. PMID: 36193735

Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases Study 2019. Armocida B, Monasta L, Sawyer S, Bustreo F, Segafredo G, Castelpietra G, Ronfani L, Pasovic M, Hay S, Perel P, Beran D. Lancet Child & Adolescent Health. 2022 Jun;6(6):367-383. doi: 10.1016/S2352-4642(22)00073-6. PMID: 35339209

Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019 a systematic analysis for the Global Burden of Disease Study 2019. Kocarnik J, Compton K, Dean F, et al. JAMA Oncology. 2022 Mar 1;8(3):420-444. doi: 10.1001/jamaoncol.2021.6987. PMID: 34967848

Design and methodological characteristics of studies using observational routinely collected health data for investigating the link between cancer and neurodegenerative diseases: protocol for a meta-research study. Catala-Lopez F, Driver J, Page M, Hutton B, Ridao M, Berrozpe-Villabona C, Alonso-Arroyo A, Fraga-Medin C, Bernal-Delgado E, Valencia A, Tabares-Seisdedos R. BMJ Open. 2022 Apr 29;12(4):e058738. doi: 10.1136/bmjopen-2021-058738. PMID: 35487732

Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019. Cousin E, Duncan B, Stein C, et al. Lancet Diabetes & Endocrinology. 2022 Mar;10(3):177-192. doi: 10.1016/S2213-8587(21)00349-1. PMID: 35143780

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019. GBD 2019 Diabetes and Air Pollution Collaborators. Lancet Planetary Health. 2022 Jul;6(7):e586-e600. doi: 10.1016/S2542-5196(22)00122-X. PMID: 35809588

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease 2019. Nichols E, Steinmetz J, Vollset S, et al. Lancet Public Health. 2022 Feb;7(2):e105-e125. doi: 10.1016/S2468-2667(21)00249-8. PMID: 34998485

Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Colorectal Cancer Collaborators. The lancet. Gastroenterology & Hepatology. 2022 Jul;7(7):627-647. doi: 10.1016/S2468-1253(22)00044-9. PMID: 35397795

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study. GBD 2019 Ageing Collaborators. BMJ-British Medical Journal. 2022 Mar 10;376:e068208. doi: 10.1136/bmj-2021-068208. PMID: 35273014

Immune-inflammatory biomarkers predict cognition and social functioning in patients with Type 2 Diabetes Mellitus, major depressive disorder, bipolar disorder, and schizophrenia: a 1-year follow-up study. Gares-Caballer M, Sanchez-Orti J, Correa-Ghisays P, Balanza-Martinez V, Selva-Vera G, Vila-Frances J, Magdalena-Benedito R, San-Martin C, Victor V, Escribano-Lopez I, Hernandez-Mijares A, Vivas-Lalinde J, Vieta E, Leza J, Tabares-Seisdedos R. Frontiers in Neurology. 2022 Jun 2;13:883927. doi: 10.3389/fneur.2022.883927. PMID: 35720107

Lifestyle behaviors, depression, and anxiety among individuals living in canada during the COVID-19 Pandemic. Simjanoski M, Cardoso T, Wollenhaupt-Aguiar B, Pfaffenseller B, Balanza-Martinez V, Minuzzi L, Kapczinski F. American Journal of Lifestyle Medicine. 2022 May 30;17(2):181-193. doi: 10.1177/15598276221102097. PMID: 36883127

Lifestyle predictors of depression and anxiety during COVID-19: a machine learning approach. Simjanoski M, Ballester P, da Mota J, De Boni R, Balanza-Martinez V, Atienza-Carbonell B, Bastos F, Frey B, Minuzzi L, Cardoso T, Kapczinski F. Trends in Psychiatry and Psychotherapy. 2022 May 31;44:e20210365. doi: 10.47626/2237-6089-2021-0365. PMID: 35240012

Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000-18: a geospatial modelling study. Local Burden of Disease Household Air Pollution Collaborators. Lancet. Global health. 2022 Oct;10(10):e1395-e1411. doi: 10.1016/S2214-109X(22)00332-1. PMID: 36113526

MICEmi: a method to identify cognitive endophenotypes of mental illnesses. Correa-Ghisays P, Vicent Sanchez-Orti J, Balanza-Martinez V, Fuentes-Dura I, Martinez-Aran A, Ruiz-Bolo L, Correa-Estrada P, Ruiz-Ruiz J, Selva-Vera G, Vila-Frances J, Macias Saint-Gerons D, San-Martin C, Ayesa-Arriola R, Tabares-Seisdedos R. European Psychiatry. 2022 Nov 28;65(1):e85. doi: 10.1192/j.eurpsy.2022.2348. PMID: 36440538

Mortality in persons with autism spectrum disorder or attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Catala-Lopez F, Hutton B, Page M, Driver J, Ridao M, Alonso-Arroyo A, Valencia A, Macias Saint-Gerons D, Tabares-Seisdedos R. JAMA Pediatrics. 2022 Apr 1;176(4):e216401. doi: 10.1001/jamapediatrics.2021.6401. PMID: 35157020

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020. GBD 2020 Alcohol Collaborators. Lancet. 2022 Jul 16;400(10347):185-235. doi: 10.1016/S0140-6736(22)00847-9. PMID: 35843246

Public stigma profile toward mental disorders across different university degrees in the University of Valencia (Spain). Ruiz J, Fuentes-Dura I, Lopez-Gilberte M, Dasi C, Pardo-Garcia C, Fuentes-Duran M, Perez-Gonzalez F, Salmeron L, Soldevila-Matias P, Vila-Frances J, Balanza-Martinez V. Frontiers in Psychiatry. 2022 Aug 12;13:951894. doi: 10.3389/fpsyt.2022.951894. PMID: 36032229

Relevance of sociodemographics and clinical tests in single- and dual-task conditions as gait speed predictors of Parkinson’s disease. San Martin Valenzuela C, Duenas L, Tomas J, Correa-Ghisays P, Serra-Ano P. Journal of Clinical Medicine. 2022 Jan 30;11(3):757. doi: 10.3390/jcm11030757. PMID: 35160208

Specific metabolic syndrome components predict cognition and social functioning in people with type 2 diabetes mellitus and severe mental disorders. Sanchez-Orti J, Balanza-Martinez V, Correa-Ghisays P, Selva-Vera G, Vila-Frances J, Magdalena-Benedito R, San-Martin C, Victor V, Escribano-Lopez I, Hernandez-Mijares A, Vivas-Lalinde J, Crespo-Facorro B, Tabares-Seisdedos R. Acta Psychiatrica Scandinavica. 2022 Sep;146(3):215-226. doi: 10.1111/acps.13433. PMID: 35359023

Strengthening therapeutic adherence and pharmacovigilance to antimalarial treatment in Manaus, Brazil: a multicomponent strategy using mHealth. Saint-Gerons D, Rodovalho S, Dias A, de Carvalho A, Beratarrechea A, Monteiro W, Machado M, da Costa C, Wada M, de Almeida M, Fonseca R, Cordeiro J, Antolini A, Nepomuceno J, Fleck K, Gasparotto F, Lacerda M, Rojas-Cortes R, Pal S, Porras A, Ade M, Castro J. Malaria Journal. 2022 Jan 29;21(1):28. doi: 10.1186/s12936-022-04047-3. PMID: 35093070

The burden of injury in Central, Eastern, and Western European sub-region: a systematic analysis from the Global Burden of Disease 2019 Study. Haagsma J, Charalampous P, Ariani F, et al. Archives of Public Health. 2022 May 20;80(1):142. doi: 10.1186/s13690-022-00891-6. PMID: 35590340

The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019. Castelpietra G, Knudsen A, Agardh E, Armocida B, Beghi M, Iburg K, Logroscino G, Ma R, Starace F, Steel N, Addolorato G, Andrei C, Andrei T, Ayuso-Mateos J, Banach M, Barnighausen T, Barone-Adesi F, Bhagavathula A, Carvalho F, Carvalho M, Chandan J, Chattu V, Couto R, Cruz-Martins N, Dargan P, Deuba K, da Silva D, Fagbamigbe A, Fernandes E, Ferrara P, Fischer F, Gaal P, Gialluisi A, Haagsma J, Haro J, Hasan M, Hasan S, Hostiuc S, Iacoviello L, Iavicoli I, Jamshidi E, Jonas J, Joo T, Jozwiak J, Katikireddi S, Kauppila J, Khan M, Kisa A, Kisa S, Kivimaki M, Koly K, Koyanagi A, Kumar M, Lallukka T, Langguth B, Ledda C, Lee P, Lega I, Linehan C, Loureiro J, Madureira-Carvalho A, Martinez-Raga J, Mathur M, McGrath J, Mechili E, Mentis A, Mestrovic T, Miazgowski B, Mirica A, Mirijello A, Moazen B, Mohammed S, Mulita F, Nagel G, Negoi I, Negoi R, Nwatah V, Padron-Monedero A, Panda-Jonas S, Pardhan S, Pasovic M, Patel J, Petcu I, Pinheiro M, Pollok R, Postma M, Rawaf D, Rawaf S, Romero-Rodriguez E, Ronfani L, Sagoe D, Sanmarchi F, Schaub M, Sharew N, Shiri R, Shokraneh F, Sigfusdottir I, Silva J, Silva R, Socea B, Szocska M, Tabares-Seisdedos R, Torrado M, Tovani-Palone M, Vasankari T, Veroux M, Viner R, Werdecker A, Winkler A, Hay S, Ferrari A, Naghavi M, Allebeck P, Monasta L. Lancet Regional Health-Europe. 2022 Apr 1;16:100341. doi: 10.1016/j.lanepe.2022.100341. PMID: 35392452

The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Adolescent Young Adult Cancer Collaborators. The Lancet. Oncology. 2022 Jan;23(1):27-52. doi: 10.1016/S1470-2045(21)00581-7. PMID: 34871551

The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Cancer Risk Factors Collaborators. Lancet. 2022 Aug 20;400(10352):563-591. doi: 10.1016/S0140-6736(22)01438-6. PMID: 35988567

Transdiagnostic neurocognitive deficits in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: a 1-year follow-up study. Correa-Ghisays P, Sanchez-Orti JV, Balanza-Martinez V, Selva-Vera G, Vila-Frances J, Magdalena-Benedito R, Victor VM, Escribano-Lopez I, Hernandez-Mijares A, Vivas-Lalinde J, San-Martin C, Crespo-Facorro B, Tabares-Seisdedos R. Journal of Affective Disorders. 2022 Mar 1;300:99-108. doi: 10.1016/j.jad.2021.12.074. PMID: 34965401

A COVID-19 drug repurposing strategy through quantitative homological similarities using a topological data analysis-based framework. Perez-Moraga R, Fores-Martos J, Suay-Garcia B, Duval J, Falco A, Climent J. Pharmaceutics. 2021 Apr 2;13(4):488. doi: 10.3390/pharmaceutics13040488. PMID: 33918313

A multicentre, randomised, controlled trial of a combined clinical treatment for first-episode psychosis. Gonzalez-Ortega I, Vega P, Echeburua E, Alberich S, Fernandez-Sevillano J, Barbeito S, Balanza-Martinez V, Vieta E, Lorente-Rovira E, Luengo A, Cerrillo E, Crespo J, Matute C, Gonzalez-Pinto A. International Journal of Environmental Research and Public Health. 2021 Jul 6;18(14):7239. doi: 10.3390/ijerph18147239. PMID: 34299697

A Trans-Omics Comparison Reveals Common Gene Expression Strategies in Four Model Organisms and Exposes Similarities and Differences between Them. Fores-Martos J, Forte A, Garcia-Martinez J, Perez-Ortin J. Cells. 2021 Feb 5;10(2):334. doi: 10.3390/cells10020334. PMID: 33562654

Adverse events associated with the use of recommended vaccines during pregnancy: An overview of systematic reviews. Macías Saint-Gerons D, Sola Arnau I, De Mucio B, Arevalo-Rodriguez I, Aleman A, Castro J, Ropero Alvarez A. Vaccine. 2021 Jul 30;39 Suppl 2:B12-B26. doi: 10.1016/j.vaccine.2020.07.048. PMID: 32972737

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018. Kinyoki D, Osgood-Zimmerman A, Bhattacharjee N, Kassebaum N, Hay S, Local Burden Dis Anaemia Collab. Nature Medicine. 2021 Oct;27(10):1761-1782. doi: 10.1038/s41591-021-01498-0. PMID: 34642490

Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression. Fores-Martos J, Cervera-Vidal R, Sierra-Roca J, Lozano-Asencio C, Fedele V, Cornelissen S, Edvarsen H, Tadeo-Cervera I, Eroles P, Lluch A, Tabares-Seisdedos R, Falco A, Van’t Veer LJ, Schmidt M, Quigley DA, Borresen-Dale AL, Kristensen VN, Balmain A, Climent J. NPJ Breast Cancer. 2021 Sep 10;7(1):118. doi: 10.1038/s41523-021-00329-2. PMID: 34508103

Education and long-term outcomes in first episode psychosis: 10-year follow-up study of the PAFIP cohort. Ayesa-Arriola R, Miguel-Corredera M, de la Foz Ortiz-Garcia V, Neergaard KD, Correa-Ghisays P, Setien-Suero E, Crespo-Facorro B. Psychological Medicine. 2021 May 6;1-12. doi: 10.1017/S0033291721001112. PMID: 33952364

Features, state and context of narcissism in drug misuse. Salazar J, Page B, Ripoll C. Substance Use & Misuse. 2021;56(1):11-24. doi: 10.1080/10826084.2020.1833923. PMID: 33100121

Four-subtest short-form of the WAIS-IV for assessment of patients diagnosed with schizophrenia. Dasi C, Fuentes-Dura I, Ruiz J, Navarro M. Revista de Psiquiatria y Salud Mental. 2021;14(3):139-147. doi: 10.1016/j.rpsmen.2019.12.003. PMID: 34362715

Four-subtest short-form of the WAIS-IV for assessment of patients diagnosed with schizophrenia. Dasi Vivo C, Fuentes Dura I, Ruiz J, Navarro M. Revista de Psiquiatria y Salud Mental. 2021;14(3):139-147. doi: 10.1016/j.rpsm.2019.12.004. PMID: 32088178

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Resp Tract Canc Collab. Lancet Respiratory Medicine. 2021 Sep;9(9):1030-1049. doi: 10.1016/S2213-2600(21)00164-8. PMID: 34411511

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019. GBD 2019 Under-5 Mortality Collaborators. Lancet. 2021 Sep 4;398(10303):870-905. doi: 10.1016/S0140-6736(21)01207-1. PMID: 34416195

How to properly use the PRISMA Statement. Sarkis-Onofre R, Catala-Lopez F, Aromataris E, Lockwood C. Systematic Reviews. 2021 Apr 19;10(1):117. doi: 10.1186/s13643-021-01671-z. PMID: 33875004

Is processing speed a valid neurocognitive endophenotype in bipolar disorder? Evidence from a longitudinal, family study. Luperdi SC, Correa-Ghisays P, Vila-Frances J, Selva-Vera G, Salazar-Fraile J, Cardoner N, Ruiz-Veguilla M, Livianos L, Tabares-Seisdedos R, Balanza-Martinez. Journal of Psychiatric Research. 2021 Jul 6;141:241-247. doi: 10.1016/j.jpsychires.2021.07.008. PMID: 34256275

Lifestyle changes and mental health during the COVID-19 pandemic: a repeated, cross-sectional web survey. Cervera-Martinez J, Atienza-Carbonell B, Mota JC, Bobes-Bascaran T, Crespo-Facorro B, Esteban C, Garcia-Portilla MP, Gomes-da-Costa S, Gonzalez-Pinto A, Jaen-Moreno MJ, Sarramea F, Vieta E, Zorrilla I, Tabares-Seisdedos R, Kapczinski F, De Boni RB, Balanza-Martinez V. Journal of Affective Disorders. 2021 Aug 24;295:173-182. doi: 10.1016/j.jad.2021.08.020. PMID: 34469856

Lifestyle in undergraduate students and demographically matched controls during the COVID-19 pandemic in Spain. Giner-Murillo M, Atienza-Carbonell B, Cervera-Martinez J, Bobes-Bascaran T, Crespo-Facorro B, De Boni R, Esteban C, Garcia-Portilla M, Gomes-da-Costa S, Gonzalez-Pinto A, Jaen-Moreno M, Kapczinski F, Ponce-Mora A, Sarramea F, Tabares-Seisdedos R, Vieta E, Zorrilla I, Balanza-Martinez V. International Journal of Environmental Research and Public Health. 2021 Jul 31;18(15):8133. doi: 10.3390/ijerph18158133. PMID: 34360426

Possible ancestral functions of the genetic and RNA operational precodes and the origin of the genetic system. Martinez-Gimenez J, Tabares-Seisdedos R. Origins of Life and Evolution of Biospheres. 2021 Jun;51(2):167-183. doi: 10.1007/s11084-021-09610-7. PMID: 34097191

Smart Safety Surveillance (3S): multi-country experience of implementing the 3S concepts and principles. Iessa N, Sarinic V, Ghazaryan L, Romanova N, Alemu A, Rungapiromnan W, Jiamsuchon P, Pokhagul P, Castro J, Saint-Gerons D, Ghukasyan G, Teferi M, Gupta M, Pal S. Drug Safety. 2021 Oct;44(10):1085-1098. doi: 10.1007/s40264-021-01100-z. PMID: 34331675

Students’ perceptions of instructional rubrics in neurological physical therapy and their effects on students’ engagement and course satisfaction. Garcia-Ros R, Ruescas-Nicolau M, Cezon-Serrano N, Carrasco J, Perez-Alenda S, Sastre-Arbona C, San Martin-Valenzuela C, Flor-Rufino C, Sanchez-Sanchez M. International Journal of Environmental Research and Public Health. 2021 May 6;18(9):4957. doi: 10.3390/ijerph18094957. PMID: 34066623

The usefulness of olanzapine plasma concentrations in monitoring treatment efficacy and metabolic disturbances in first-episode psychosis. Arnaiz J, Rodrigues-Silva C, Mezquida G, Amoretti S, Cuesta M, Fraguas D, Lobo A, Gonzalez-Pinto A, Diaz-Caneja M, Corripio I, Vieta E, Baeza I, Mane A, Garcia-Rizo C, Bioque M, Saiz J, Bernardo M, Mas S, Balanza Martinez V. Psychopharmacology. 2021 Mar;238(3):665-676. doi: 10.1007/s00213-020-05715-5. PMID: 33230696

Torsade de pointes associated with chloroquine, hydroxychloroquine, and azithromycin: a retrospective analysis of individual case safety reports from VigiBase. Saint-Gerons Macias D, Tabares-Seisdedos R. European Journal of Clinical Pharmacology. 2021 Oct;77(10):1513-1521. doi: 10.1007/s00228-021-03133-w. PMID: 33938974

Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050. Global Burden Dis Hlth Financing. Lancet. 2021 Oct 9;398(10308):1317-1343. doi: 10.1016/S0140-6736(21)01258-7. PMID: 34562388

Transcriptomic and genetic associations between alzheimer’s disease, parkinson’s disease, and cancer. Fores-Martos J, Boullosa C, Rodrigo-Dominguez D, Sanchez-Valle J, Suay-Garcia B, Climent J, Falco A, Valencia A, Puig-Butille J, Puig S, Tabares-Seisdedos R. Cancers. 2021 Jun 15;13(12):2990. doi: 10.3390/cancers13122990. PMID: 34203763

Treatment patterns and appropriateness of antipsychotic prescriptions in patients with schizophrenia. Gamon V, Hurtado I, Salazar-Fraile J, Sanfelix-Gimeno G. Scientific Reports. 2021 Jun 29;11(1):13509. doi: 10.1038/s41598-021-92731-w. PMID: 34188093

Use of multidimensional item response theory methods for dementia prevalence prediction: an example using the Health and Retirement Survey and the Aging, Demographics, and Memory Study. Nichols E, Abd-Allah F, Abdoli A, et al. BMC Medical Informatics and Decision Making. 2021 Aug 11;21(1):241. doi: 10.1186/s12911-021-01590-y. PMID: 34380485

Proyectos
Referencia: PID2021-129099OB-100
Título: MULTImorbilidad en personas con trastornos del Sistema Nervioso Central: una prioridad para la salud global desde los registros médicos
Entidad Financiadora: Ministerio de Ciencia e Innovación
Investigador principal: Rafael Tabarés Seisdedos
Duración: 2022 – 2024
Presupuesto: 104.060 €
Referencia: PI20-00066
Título: Adaptación y validación de la batería cognitiva Brief Assessment of Cognition App (BAC App) y del Virtual Reality Assessment of Functional Capacity Tool (VRFCAT) para su uso en España
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Rosa Ayesa Arriola
Duración: 2021 – 2023
Presupuesto: 87.120 €
Referencia: 201904DMC
Título: Drug safety and effectiveness network methods and apllications group in indirect comparisons (DSEN MAGIC) Team
Entidad Financiadora: Canadian Institutes of Health Research/Drug Safety and Effectiveness Network
Investigador principal: Hutton B, Moher D, Straus SE, Wells G
Duración: 2019 – 2023
Presupuesto: 2.875.010,80
Referencia: PI17/00719
Título: Identificación de biomarcadores epigenéticos periféricos asociados con el déficit neurocognitivo en personas con trastorno bipolar, depresión, esquizofrenia y diabetes tipo 2
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Rafael Tabarés Seisdedos
Duración: 2018 – 2020
Presupuesto: 105.270 €
Referencia: CB07/09/0021
Título: CIBER de Salud Mental (CIBERSAM)
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Rafael Tabarés Seisdedos
Duración: 2015 –
Presupuesto:
+ Información
Endorsement of guidelines for reporting economic evaluation studies by Spanish biomedical journals. Catalá-López F, Ridao M, Bernal-Delgado E, Moher D, Repullo JR. Gaceta Sanitaria. 2019 May-Jun;33(3):255-258. doi: 10.1016/j.gaceta.2018.12.006. PMID: 30878246

Reporting guidelines for health research: protocol for a cross-sectional analysis of the EQUATOR Network Library. Catalá-López F, Alonso-Arroyo A, Page MJ, Hutton B, Ridao M, Tabarés-Seisdedos R, Aleixandre-Benavent R, Moher D. BMJ Open. 2019 Mar 4;9(3):e022769. doi: 10.1136/bmjopen-2018-022769. PMID: 30837245

Título: Eficacia de un programa de musicoterapia como tratamiento complementario a la intervención psicosocial en la recuperación de la esquizofrenia y otras psicosis
Doctorando: Pérez Aguado, Oscar
Director: Fuentes Dura, Inmaculada; Ruíz Ruiz, Juan Carlos; Dasi Vivo, Carmen
Fecha: 24/03/2023
Universidad: Universitat de València

Título: Estudio comparativo sobre la presencia del estigma social asociado al trastorno mental grave en estudiantes de psicología de la Universitat de València
Doctorando: López Palanca, Irene
Director: Sancerni Beitia, María Dolores; Ruíz Ruiz, Juan Carlos; Fuentes Dura, Inmaculada
Fecha: 03/02/2023
Universidad: Universitat de València

Título: Epidemiological and molecular associations between central nervous system disorders and cancer
Doctorando: Forés Martos, Jaume
Director: Tabarés Seisdedos, Rafael; Catalá López, Ferrán; Climent Bataller Joan
Fecha: 21/07/2021
Universidad: Universitat de València

Título: Efectos de un programa de intervención psicoeducativa en la calidad de vida de los/las pacientes durante sus tratamientos de Reproducción Asistida
Doctorando: Abad Villavicencio, Ruth Elizabeth
Director: Fuentes Durá, Inmaculada; Dasí Vivo, Carmen; Romeu Villarroya, Mónica
Fecha: 21/05/2021
Universidad: Universitat de València

Título: Funcionamiento neurocognitivo y psicosocial de pacientes con trastorno bipolar en una Unidad de Salud Mental
Doctorando: Vidal Rubio, Sonia del Lluch
Director: Balanzá Martínez, Vicent; Romeu Climent, José Enrique
Fecha: 19/06/2019
Universidad: Universitat de València