Dr. Rafael Tabarés Seisdedos

Investigador Principal
Grupo de Investigación en Autonomía Personal, Dependencia y Trastornos Mentales Graves

Presentación


El Profesor Tabarés es Catedrático de Psiquiatría de la Universitat de València, Investigador Principal en el Centro de Investigaciones Biomédicas en Red de Salud Mental (CIBERSAM) del Ministerio de Ciencia e Innovación, y de uno de los grupos de Excelencia del programa PROMETEO, Director del Grupo de Investigación en Trastornos Mentales Graves de la Universitat de València y Coordinador del microcluster de “Autonomía Personal, Dependencia y Trastornos Mentales Graves, MCI” dentro del Campus de Excelencia VLC/CAMPUS del Ministerio de Ciencia e Innovación constituido en Unidad de investigación, miembro del Comité Científico de Expertos del Ministerio de Sanidad y Política Social-IMSERSO para la aplicación del Centro de Referencia de Atención socio-sanitaria para Personas con Trastorno Mental Grave en Valencia. Miembro del comité editorial y de expertos de varias revistas de prestigio, ha obtenido múltiples premios y reconocimientos, destacando entre ellos:

– Formar parte del listado de investigadores altamente citados (indicador HiCi; Thomson-Reuters, 2013). Listado conjunto de todas las áreas de conocimiento compuesto por 112 Investigadores altamente citados en España, de los cuales, cinco de ellos corresponden a la Universitat de València.

– The Aristotles Reserch Award al estudio: Mutations in genes regulating neuronal migration predict reduced prefrontal cognition in schizophrenia and bipolar disorder: A preliminary study. 2nd International congress on BRAIN AND BEHAVIOUR, at the Grand HotelPalace, Thessaloniki, Greece. 2005

– Premio Investigador de Referencia dentro del Programa de Excelencia Investigadora de la Sociedad Española de Psiquiatría Biológica. IIIX Congreso Nacional de Psiquiatría. Madrid 2009

– Premio de la Real Academia de Medicina y Ciencias Afines de la Comunitat Valenciana 2013 a la mejor investigación científica por el trabajo de investigación titulado: “Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50 Observational Studies”.

Investigador
Principal
Dr. Rafael Tabarés Seisdedos

rafael.tabares@uv.es

Publicaciones
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018. Kinyoki D, Osgood-Zimmerman A, Bhattacharjee N, Kassebaum N, Hay S, Local Burden Dis Anaemia Collab. Nature Medicine. 2021 Oct;27(10):1761-1782. doi: 10.1038/s41591-021-01498-0. PMID: 34642490

Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression. Fores-Martos J, Cervera-Vidal R, Sierra-Roca J, Lozano-Asencio C, Fedele V, Cornelissen S, Edvarsen H, Tadeo-Cervera I, Eroles P, Lluch A, Tabares-Seisdedos R, Falco A, Van’t Veer LJ, Schmidt M, Quigley DA, Borresen-Dale AL, Kristensen VN, Balmain A, Climent J. NPJ Breast Cancer. 2021 Sep 10;7(1):118. doi: 10.1038/s41523-021-00329-2. PMID: 34508103

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Resp Tract Canc Collab. Lancet Respiratory Medicine. 2021 Sep;9(9):1030-1049. doi: 10.1016/S2213-2600(21)00164-8. PMID: 34411511

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019. GBD 2019 Under-5 Mortality Collaborators. Lancet. 2021 Sep 4;398(10303):870-905. doi: 10.1016/S0140-6736(21)01207-1. PMID: 34416195

Is processing speed a valid neurocognitive endophenotype in bipolar disorder? Evidence from a longitudinal, family study. Luperdi SC, Correa-Ghisays P, Vila-Frances J, Selva-Vera G, Salazar-Fraile J, Cardoner N, Ruiz-Veguilla M, Livianos L, Tabares-Seisdedos R, Balanza-Martinez. Journal of Psychiatric Research. 2021 Jul 6;141:241-247. doi: 10.1016/j.jpsychires.2021.07.008. PMID: 34256275

Lifestyle changes and mental health during the COVID-19 pandemic: a repeated, cross-sectional web survey. Cervera-Martinez J, Atienza-Carbonell B, Mota JC, Bobes-Bascaran T, Crespo-Facorro B, Esteban C, Garcia-Portilla MP, Gomes-da-Costa S, Gonzalez-Pinto A, Jaen-Moreno MJ, Sarramea F, Vieta E, Zorrilla I, Tabares-Seisdedos R, Kapczinski F, De Boni RB, Balanza-Martinez V. Journal of Affective Disorders. 2021 Aug 24;295:173-182. doi: 10.1016/j.jad.2021.08.020. PMID: 34469856

Lifestyle in undergraduate students and demographically matched controls during the COVID-19 pandemic in Spain. Giner-Murillo M, Atienza-Carbonell B, Cervera-Martinez J, Bobes-Bascaran T, Crespo-Facorro B, De Boni R, Esteban C, Garcia-Portilla M, Gomes-da-Costa S, Gonzalez-Pinto A, Jaen-Moreno M, Kapczinski F, Ponce-Mora A, Sarramea F, Tabares-Seisdedos R, Vieta E, Zorrilla I, Balanza-Martinez V. International Journal of Environmental Research and Public Health. 2021 Jul 31;18(15):8133. doi: 10.3390/ijerph18158133. PMID: 34360426

Possible ancestral functions of the genetic and RNA operational precodes and the origin of the genetic system. Martinez-Gimenez J, Tabares-Seisdedos R. Origins of Life and Evolution of Biospheres. 2021 Jun;51(2):167-183. doi: 10.1007/s11084-021-09610-7. PMID: 34097191

Torsade de pointes associated with chloroquine, hydroxychloroquine, and azithromycin: a retrospective analysis of individual case safety reports from VigiBase. Saint-Gerons Macias D, Tabares-Seisdedos R. European Journal of Clinical Pharmacology. 2021 Oct;77(10):1513-1521. doi: 10.1007/s00228-021-03133-w. PMID: 33938974

Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050. Global Burden Dis Hlth Financing. Lancet. 2021 Oct 9;398(10308):1317-1343. doi: 10.1016/S0140-6736(21)01258-7. PMID: 34562388

Transcriptomic and genetic associations between alzheimer’s disease, parkinson’s disease, and cancer. Fores-Martos J, Boullosa C, Rodrigo-Dominguez D, Sanchez-Valle J, Suay-Garcia B, Climent J, Falco A, Valencia A, Puig-Butille J, Puig S, Tabares-Seisdedos R. Cancers. 2021 Jun 15;13(12):2990. doi: 10.3390/cancers13122990. PMID: 34203763

Transdiagnostic neurocognitive deficits in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: a 1-year follow-up study. Correa-Ghisays P, Sanchez-Orti JV, Balanza-Martinez V, Selva-Vera G, Vila-Frances J, Magdalena-Benedito R, Victor VM, Escribano-Lopez I, Hernandez-Mijares A, Vivas-Lalinde J, San-Martin C, Crespo-Facorro B, Tabares-Seisdedos R. Journal of Affective Disorders. 2021 Dec 26;300:99-108. doi: 10.1016/j.jad.2021.12.074. PMID: 34965401

Use of multidimensional item response theory methods for dementia prevalence prediction: an example using the Health and Retirement Survey and the Aging, Demographics, and Memory Study. Nichols E, Abd-Allah F, Abdoli A, et al. BMC Medical Informatics and Decision Making. 2021 Aug 11;21(1):241. doi: 10.1186/s12911-021-01590-y. PMID: 34380485

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017. LBD Double Burden of Malnutrition Collaborators, Tabarés Seisdedos R, LBD Double Burden of Malnutrition Collaborators. Nature Medicine. 2020 Aug;26(8):1308. doi: 10.1038/s41591-020-0972-7. PMID: 32616917

Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017. Haagsma J, James S, Castle C, et al. Injury prevention. 2020 Oct;26(Supp 1):i12-i26. doi: 10.1136/injuryprev-2019-043296. PMID: 31915273

Childhood trauma and substance use underlying psychosis: a systematic review. Setien-Suero E, Suarez-Pinilla P, Ferro A, TABARÉS SEISDEDOS R, Crespo-Facorro B, Ayesa-Arriola R. European Journal of Psychotraumatology. 2020 Apr 23;11(1):1748342. doi: 10.1080/20008198.2020.1748342. PMID: 32373286

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. James S, Castle C, Dingels Z, et al. Injury Prevention. 2020 Oct;26(Supp 1):i125-i153. doi: 10.1136/injuryprev-2019-043531. PMID: 32839249

Five insights from the Global Burden of Disease Study 2019. Global Burden Dis 2019. Lancet. 2020 Oct 17;396(10258):1135-1159. doi: 10.1016/S0140-6736(20)31404-5. PMID: 33069324

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. GBD 2019 Demographics. Lancet. 2020 Oct 17;396(10258):1160-1203. doi: 10.1016/S0140-6736(20)30977-6. PMID: 33069325

Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016. Driscoll T, Rushton L, Steenland K, GBD 2016 Occupational Carcinogens Collaborators. Occupational And Environmental Medicine. 2020 Mar;77(3):151-159. doi: 10.1136/oemed-2019-106012. PMID: 32054819

Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016. GBD 2016 Occupational Chronic Respiratory Risk Factors Collaborators. Occupational And Environmental Medicine. 2020 Mar;77(3):142-150. doi: 10.1136/oemed-2019-106013. PMID: 32054818

Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016. GBD 2016 Occupational Risk Factors Collaborators. Occupational And Environmental Medicine. 2020 Mar;77(3):133-141. doi: 10.1136/oemed-2019-106008. PMID: 32054817

Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Diss Injuries. Lancet. 2020 Oct 17;396(10258):1204-1222. doi: 10.1016/S0140-6736(20)30925-9. PMID: 33069326

Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. GBD 2019 Risk Factors. Lancet. 2020 Oct 17;396(10258):1223-1249. doi: 10.1016/S0140-6736(20)30752-2. PMID: 33069327

Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017. James S, Castle C, Dingels Z, et al. Injury Prevention. 2020 Oct;26(Supp 1):i96-i114. doi: 10.1136/injuryprev-2019-043494. PMID: 32332142

Global mapping of randomised trials related articles published in high-impact-factor medical journals: a cross-sectional analysis. Catala Lopez F, Aleixandre-Benavent R, Caulley L, Hutton B, Tabarés Seisdedos R, Moher D, Alonso-Arroyo A. Trials. 2020 Jan 7;21(1):34. doi: 10.1186/s13063-019-3944-9. PMID: 31910857

Grip Strength, Neurocognition, and Social Functioning in People WithType-2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizophrenia. Alino-Dies M, Sanchez-Orti J, Correa-Ghisays P, Balanza-Martinez V, Vila-Frances J, Selva-Vera G, Correa-Estrada P, Fores-Martos J, San-Martin Valenzuela C, Monfort-Panego M, Ayesa-Arriola R, Ruiz-Veguilla M, Crespo-Facorro B, Tabares-Seisdedos R. Frontiers in Psychology. 2020 Nov 25;11:525231. doi: 10.3389/fpsyg.2020.525231. PMID: 33324271

Health sector spending and spending on HIV/AIDS, tuberculosis, and malaria, and development assistance for health: progress towards Sustainable Development Goal 3. Global Burden of Disease Health Financing Collaborator Network, Tabarés Seisdedos R, Global Burden of Disease Health Financing Collaborator Network. Lancet. 2020 5-11 Sep;396(10252):693-724. doi: 10.1016/S0140-6736(20)30608-5. PMID: 32334655

Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships. Sanchez-Valle J, Tejero H, Fernandez J, Juan D, Urda-Garcia B, Capella-Gutierrez S, Al-Shahrour F, Tabarés Seisdedos R, Baudot A, Pancaldi V, Valencia A. Nature Communications. 2020 Jun 5;11(1):2854. doi: 10.1038/s41467-020-16540-x. PMID: 32504002

Mapping child growth failure across low- and middle-income countries. Local Burden of Disease Child Growth Failure Collaborators. Nature. 2020 Jan;577(7789):231-234. doi: 10.1038/s41586-019-1878-8. PMID: 31915393

Mapping disparities in education across low- and middle-income countries. Local Burden of Disease Educational Attainment Collaborators. Nature. 2020 Jan;577(7789):235-238. doi: 10.1038/s41586-019-1872-1. PMID: 31875853

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17. Local Burden of Disease WaSH Collaborators. The Lancet. Global health. 2020 Sep;8(9):e1162-e1185. doi: 10.1016/S2214-109X(20)30278-3. PMID: 32827479

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17. Local Burden of Disease Diarrhoea Collaborators. The Lancet. Global health. 2020 Aug;8(8):e1038-e1060. doi: 10.1016/S2214-109X(20)30230-8. PMID: 32710861

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017. LBD Double Burden of Malnutrition Collaborators. Nature Medicine. 2020 May;26(5):750-759. doi: 10.1038/s41591-020-0807-6. PMID: 32313249

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Gbd Universal Hlth Coverage. Lancet. 2020 Oct 17;396(10258):1250-1284. doi: 10.1016/S0140-6736(20)30750-9. PMID: 32861314

Morbidity and mortality from road injuries: results from the Global Burden of Disease Study 2017. James S, Lucchesi L, Bisignano C, Castle C, Dingels Z, Fox J, Hamilton E, Liu Z, McCracken D, Nixon M, Sylte D, Roberts N, Adebayo O, Aghamolaei T, Alghnam S, Aljunid S, Almasi-Hashiani A, Badawi A, Behzadifar M, Behzadifar M, Bekru E, Bennett D, Chapman J, Deribe K, Duko Adema B, Fatahi Y, Gelaw B, Getahun E, Hendrie D, Henok A, Hidru H, Hosseinzadeh M, Hu G, Jahani M, Jakovljevic M, Jalilian F, Joseph N, Karami M, Kelbore A, Khan M, Kim Y, Koul P, La Vecchia C, Linn S, Majdzadeh R, Mehndiratta M, Memiah P, Mengesha M, Merie H, R Miller T, Mirzaei-Alavijeh M, Mohammad Darwesh A, Mohammad Gholi Mezerji N, Mohammadibakhsh R, Moodley Y, Moradi-Lakeh M, Musa K, Nascimento B, Nikbakhsh R, Nyasulu P, Omar Bali A, Onwujekwe O, Pati S, Pourmirza Kalhori R, Salehi F, Shahabi S, Shallo S, Shamsizadeh M, Sharafi Z, Shukla S, Sobhiyeh M, Soriano J, Sykes B, Tabarés Seisdedos R, Tadesse D, Tefera Y, Tehrani-Banihashemi A, Tlou B, Topor-Madry R, Wiangkham T, Yaseri M, Yaya S, Yenesew M, Younis M, Ziapour A, Zodpey S, Pigott D, Reiner R, Hay S, Lopez A, Mokdad A. Injury Prevention. 2020 Oct;26(Supp 1):i46-i56. doi: 10.1136/injuryprev-2019-043302. PMID: 31915274

Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy. San Martín Valenzuela C, Borras-Barrachina A, Gallego Roig J, Urios Lluch M, Mestre Salvador V, Correa Ghisays P, Ballester Ferre M, Escudero Garcia A, Tosca Cuquerella J, Monton Rodríguez C, Rios M, Kosenko E, Felipo V, Tabarés Seisdedos R, Selva Vera G, Montoliu Félix M. Journal of Clinical Medicine. 2020 Jul 8;9(7):2154. doi: 10.3390/jcm9072154. PMID: 32650464

Peripheral Oxidative Stress Markers in Patients with Bipolar Disorder during Euthymia and Siblings. Tatay-Manteiga A, Balanza Martinez V, Bristot G, Tabarés Seisdedos R, Kapczinski F, Cauli O. Endocrine, metabolic & immune disorders drug targets. 2020;20(1):77-86. doi: 10.2174/1871530319666190307165355. PMID: 30848220

Reproducible research practices, openness and transparency in health economic evaluations: study protocol for a cross-sectional comparative analysis. Catala Lopez F, Caulley L, Ridao M, Hutton B, Husereau D, Drummond M, Alonso-Arroyo A, Pardo-Fernandez M, Bernal-Delgado E, Meneu R, Tabarés Seisdedos R, Repullo J, Moher D. BMJ Open. 2020 Feb 13;10(2):e034463. doi: 10.1136/bmjopen-2019-034463. PMID: 32060160

Proyectos
Referencia: PI17/00719
Título: Identificación de biomarcadores epigenéticos periféricos asociados con el déficit neurocognitivo en personas con trastorno bipolar, depresión, esquizofrenia y diabetes tipo 2
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Rafael Tabarés Seisdedos
Duración: 2018 – 2020
Presupuesto: 105.270 €

Referencia: CB07/09/0021
Título: CIBER de Salud Mental (CIBERSAM)
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Rafael Tabarés Seisdedos
Duración: 2015 –
Presupuesto:

+ Información
Reporting guidelines for health research: protocol for a cross-sectional analysis of the EQUATOR Network Library. Catalá-López F, Alonso-Arroyo A, Page MJ, Hutton B, Ridao M, Tabarés-Seisdedos R, Aleixandre-Benavent R, Moher D. BMJ Open. 2019 Mar 4;9(3):e022769. doi: 10.1136/bmjopen-2018-022769. PMID: 30837245

Título: Terapia celular en enfermedades desmielinizantes
Doctorando: Jaramillo Merchán, Jesús Alfonso
Director: Martínez Pérez, Salvador; Jones Barbera, Jonathan Richard
Fecha: 12/02/2021
Universidad: Universitat de València

Título: Efectos de un programa de intervención psicoeducativa en la calidad de vida de los/las pacientes durante sus tratamientos de Reproducción Asistida
Doctorando: Abad Villavicencio, Ruth Elizabeth
Director: Fuentes Durá, Inmaculada; Dasí Vivo, Carmen; Romeu Villarroya, Mónica
Fecha: 21/05/2021
Universidad: Universitat de València

Título: Funcionamiento neurocognitivo y psicosocial de pacientes con trastorno bipolar en una Unidad de Salud Mental
Doctorando: Vidal Rubio, Sonia del Lluch
Director: Balanzá Martínez, Vicent; Romeu Climent, José Enrique
Fecha: 19/06/2019
Universidad: Universitat de València