Grupo de investigación en Insuficiencia Cardiaca

Área de Cardiovascular

Caracterización fenotípica del síndrome de la insuficiencia cardiaca

Profundizar en mecanismos fisiopatológicos en los diferentes fenotipos de la enfermedad

Desarrollo de herramientas que permitan mejorar el proceso diagnóstico de la insuficiencia cardiaca

Estratificación de riesgo en pacientes con insuficiencia cardiaca aguda y crónica

Evaluación de diferentes estrategias terapéuticas y de monitorización que permitan mejorare pronóstico de la insuficiencia cardiaca

Coordinador
Dr. Julio Núñez Villota
yulnunez@gmail.com/juenuvi@uv.es

INVESTIGADORES
R4 Senior
R3 Consolidado

Julio Núñez Villota    

R2 Novel / Emergente

Enrique Santas Olmeda
Gema Miñana Escrivá
Patricia Palau Sampio

R1 Predoctoral

Ana Belén Paes Martí
Raquel Heredia Cambra

STAFF
Colaborador/a

Rafael de la Espriella Juan

Enfermero/a

Alberto Ramírez Sáiz
Ana Martínez Álvarez
José Manuel Civera Gómez

Técnico/a

Adriana Conesa Bona

Apoyo
Publicaciones
Antigen carbohydrate 125 as a biomarker in heart failure: a narrative review. Nunez J, de la Espriella R, Minana G, Santas E, Llacer P, Nunez E, Palau P, Bodi V, Chorro F, Sanchis J, Lupon J, Bayes-Genis A. European Journal of Heart Failure. 2021 Jul 9. doi: 10.1002/ejhf.2295. PMID: 34241936

Bacterial metabolites trimethylamine N-oxide and butyrate as surrogates of small intestinal bacterial overgrowth in patients with a recent decompensated heart failure. Mollar A, Marrachelli V, Nunez E, Monleon D, Bodi V, Sanchis J, Navarro D, Nunez J. Scientific reports. 2021 Mar 17;11(1):6110. doi: 10.1038/s41598-021-85527-5. PMID: 33731747

Clinical utility of antigen carbohydrate 125 for planning the optimal length of stay in acute heart failure. Lorenzo M, Palau P, Llacer P, Dominguez E, Ventura B, Nunez G, Minana G, Solsona J, Santas E, De La Espriella R, Bodi V, Nunez E, Sanchis J, Bayes-Genis A, Nunez J. European Journal of Internal Medicine. 2021 Jun 12;S0953-6205(21)00196-5. doi: 10.1016/j.ejim.2021.05.037. PMID: 34130879

Comorbidity burden and revascularization benefit in elderly patients with acute coronary syndrome. Sanchis Fores J, Garcia Acuna J, Raposeiras S, Barrabes J, Cordero A, Martinez-Selles M, Bardaji A, Diez-Villanueva P, Marin F, Ruiz-Nodar J, Vicente-Ibarra N, Alonso Salinas G, Rigueiro P, Abu-Assi E, Formiga F, Nuñez Villota J, Nuñez Benito E, Ariza-Sole A. Revista Espanola de Cardiologia (English ed.). 2021 Sep;74(9):765-772. doi: 10.1016/j.rec.2020.06.015. PMID: 32778402

Coronary Revascularization and Long-Term Survivorship in Chronic Coronary Syndrome. Gabaldon-Perez A, Marcos-Garces V, Gavara J, Rios-Navarro C, Minana G, Bayes-Genis A, Husser O, Sanchis J, Nunez J, Chorro F, Bodi V. Journal of Clinical Medicine. 2021 Feb 5;10(4):610. doi: 10.3390/jcm10040610. PMID: 33562869

Decoding empagliflozin’s molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence. Bayes-Genis A, Iborra-Egea O, Spitaleri G, Domingo M, Revuelta-Lopez E, Codina P, Cediel G, Santiago-Vacas E, Cserkoova A, Pascual-Figal D, Nunez J, Lupon J. Scientific Reports. 2021 Jun 8;11(1):12025. doi: 10.1038/s41598-021-91546-z. PMID: 34103605

Decongestion discriminates risk for one-year mortality in patients with improving renal function in acute heart failure. Wettersten N, Horiuchi Y, van Veldhuisen D, Ix J, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos M, Cannon C, Mueller G, Birkhahn R, Taub P, Vilke G, Duff S, McDonald K, Mahon N, Nunez J, Briguori C, Passino C, Maisel A, Murray P. European Journal of Heart Failure. 2021 Jul;23(7):1122-1130. doi: 10.1002/ejhf.2179. PMID: 33788989

Early urinary sodium trajectory and risk of adverse outcomes in acute heart failure and renal dysfunction. De La Espriella Juan R, Nuñez Benito E, Llàcer P, Garcia Blas S, Ventura Haro S, Núñez J, Sánchez R, Facila De La Esperanza R, Vaquer Santamaria J, Bodí Peris V, Santas Olmeda E, Miñana Escriva G, Mollar Fernandez A, Núñez Marín G, Chorro Gascó F, Górriz Teruel J, Sanchis Fores J, Bayés-Genis A, Nuñez Villota J. Revista Espanola de Cardiologia (English ed.). 2021 Jul;74(7):616-623. doi: 10.1016/j.rec.2020.06.004. PMID: 32624444

EpCAM and microvascular obstruction in patients with STEMI: a cardiac magnetic resonance study. Rios-Navarro C, Gavara J, Nunez J, Revuelta-Lopez E, Monmeneu JV, Lopez-Lereu MP, de Dios E, Perez-Sole N, Vila JM, Oltra R, Chorro FJ, Bayes-Genis A, Bodi V. Revista Espanola de Cardiologia (English ed.). 2021 May 24;S1885-5857(21)00135-3. doi: 10.1016/j.rec.2021.04.006. PMID: 34045168

Heart failure with preserved ejection fraction: an urgent need for precision medicine. Minana, G, Nunez J. Journal of Clinical Medicine. 2021 Apr 21;10(9):1801. doi: 10.3390/jcm10091801. PMID: 33918988

Homocysteine and long-term recurrent infarction following an acute coronary síndrome. Miñana Escriva G, Gil Cayuela C, Facila De La Esperanza R, Bodí Peris V, Valero Picher E, Mollar Fernandez A, Marco M, Garcia-Ballester T, Zorio B, Marti-Cervera J, Nuñez Benito E, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Cardiology Journal. 2021;28(4):598-606. doi: 10.5603/CJ.a2020.0170. PMID: 33346372

Hypoplasia of the posterior mitral valve leaflet: Don’t forget to look beyond the mitral valve. Gabaldón-Pérez A, Marcos-Garcés V, Muñoz Gil J, Chorro Gascó FJ, Santas E. Echocardiography. 2021 Jan;38(1):142-143. doi: 10.1111/echo.14910. PMID: 33107084

Inaccuracy of a non-invasive estimation of pulmonary vascular resistance assessed by cardiovascular magnetic resonance in heart failure patients. Rumiz E, Cubillos A, Vilar J, Garcia P, Berenguer A, Facila L, Valero E, Vidal V, Morell S, Nunez J. Scientific Reports. 2021 Aug 16;11(1):16597. doi: 10.1038/s41598-021-95897-5. PMID: 34400680

Iron deficiency and short-term adverse events in patients with decompensated heart failure. Palau P, Llacer P, Dominguez E, Tormo J, Zakarne R, Mollar A, Martinez A, Minana G, Santas E, Almenar L, Facila L, de la Espriella R, Nunez E, Manzano L, Bayes-Genis A, Nunez J. Clinical Research in Cardiology. 2021 Mar 15. doi: 10.1007/s00392-021-01832-z. PMID: 33721056

Long-term mortality and trajectory of potassium measurements following an episode of acute severe hyperkalemia. Gorriz J, D’Marco L, Pastor-Gonzalez A, Molina P, Gonzalez-Rico M, Puchades M, Sanchis I, Escudero V, Estan N, de la Espriella R, Nunez E, Pallardo L, Nunez J. Nephrology, dialysis, transplantation. 2021 Jan 28;gfab003. doi: 10.1093/ndt/gfab003. PMID: 33508124

Long-term prognostic implications of revascularization in patients with known or suspected chronic coronary syndromes without ischemia in vasodilator stress cardiovascular magnetic resonance. Minana G, Nunez J, Marcos-Garces V, Gavara J, Rios-Navarro C, Bodi V. International Journal of Cardiology. 2021 Apr 23;S0167-5273(21)00673-2. doi: 10.1016/j.ijcard.2021.04.037. PMID: 33895211

Long-Term Prognostic Value of Cognitive Impairment on Top of Frailty in Older Adults after Acute Coronary Syndrome. Sanchis J, Bonanad C, Garcia-Blas S, Ruiz V, Fernandez-Cisnal A, Sastre C, Ruescas A, Valero E, Gonzalez J, Mollar A, Minana G, Nunez J. Journal of Clinical Medicine. 2021 Jan 24;10(3):444. doi: 10.3390/jcm10030444. PMID: 33498816

Longitudinal strain in remote non-infarcted myocardium by tissue tracking CMR: characterization, dynamics, structural and prognostic implications. GAVARA DOÑATE J, Rodriguez-Palomares J, Rios Navarro C, Valente F, Monmeneu J, Lopez-Lereu M, Ferreira-Gonzalez I, Garcia Del Blanco B, Otaegui I, Canoves Femenia J, De Dios Lluch E, Pérez Solé N, Racugno P, Bonanad Lozano C, Miñana Escriva G, Marcos Garcés V, Barrabes J, Evangelista A, Moratal D, Bayes-Genis A, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. The International Journal Of Cardiovascular Imaging. 2021 Jan;37(1):241-253. doi: 10.1007/s10554-020-01890-w. PMID: 32488452

Magnetic resonance assessment of left ventricular ejection fraction at any time post-infarction for prediction of subsequent events in a large multicenter STEMI Registry. Gavara J, Marcos-Garces V, Lopez-Lereu, MP, Monmeneu JV, Rios-Navarro C, de Dios E, Perez N, Merenciano H, Gabaldon A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Nunez E, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Rodriguez-Palomares JF, Ortiz-Perez JT, Bodi V. Journal of Magnetic Resonance Imaging. 2021 Jun 16. doi: 10.1002/jmri.27789. PMID: 34137478

Mid-term Prognostic Implication of hospitalized COVID-19 patients with Prior Heart Failure diagnosis. Llacer P, Manzano L, Fernandez C, Moreno M, Nunez J. European Journal of Internal Medicine. 2021 Feb 25;S0953-6205(21)00058-3. doi: 10.1016/j.ejim.2021.02.013. PMID: 33676804

Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018. Spitaleri G, Lupon J, Domingo M, Santiago-Vacas E, Codina P, Zamora E, Cediel G, Santesmases J, Diez-Quevedo C, Troya M, Boldo M, Altmir S, Alonso N, Gonzalez B, Nunez J, Bayes-Genis A. Scientific reports. 2021 Jan 12;11(1):732. doi: 10.1038/s41598-020-79926-3. PMID: 33436787

Prognostic value of indexed pulmonary artery diameter assessed by cardiac magnetic resonance imaging in patients with acute heart failure. Nuñez Villota J, Merenciano González H, Santas Olmeda E, Lopez Lereu M, Monmeneu Menadas J, Valero Picher E. Revista Espanola De Cardiologia (english Ed.). 2021 Mar;74(3):267-269. doi: 10.1016/j.rec.2020.06.039. PMID: 32978097

Regulatory network analysis in estradiol-treated human endothelial cells. Perez-Cremades D, Paes A, Vidal-Gomez X, Mompeon A, Hermenegildo C, Novella S. International Journal of Molecular Sciences. 2021 Jul 30;22(15):8193. doi: 10.3390/ijms22158193. PMID: 34360960

Relation of Decongestion and Time to Diuretics to Biomarker Changes and Outcomes in Acute Heart Failure. Horiuchi Y, Wettersten N, van Veldhuisen D, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos M, Cannon C, Mueller G, Birkhahn R, Taub P, Vilke G, Barnett O, McDonald K, Mahon N, Nunez J, Briguori C, Passino C, Maisel A, Murray P. American Journal of Cardiology. 2021 Feb 19;S0002-9149(21)00152-1. doi: 10.1016/j.amjcard.2021.01.040. PMID: 33617811

Right ventricular function and iron deficiency in acute heart failure. Miñana Escriva G, Santas Olmeda E, De La Espriella Juan R, Nunez E, Lorenzo Hernández M, Núñez Marín G, Valero Picher E, Bodí Peris V, Chorro Gascó F, Sanchis Fores J, Cohen-Solal A, Bayes-Genis A, Nuñez Villota J. European heart journal. Acute cardiovascular care. 2021 May 25;10(4):406-414. doi: 10.1093/ehjacc/zuaa028. PMID: 33620455

Sex differences on new-onset heart failure in patients with known or suspected coronary artery disease. Nunez J, Lorenzo M, Minana G, Palau P, Monmeneu JV, Lopez-Lereu MP, Gavara J, Marcos-Garces V, Rios-Navarro C, Perez N, de Dios E, Nunez E, Sanchis J, Chorro FJ, Bayes-Genis A, Bodi V. European Journal of Preventive Cardiology. 2021 May 10;zwab078. doi: 10.1093/eurjpc/zwab078. PMID: 33970216

The ‘Peptide for Life’ Initiative: a call for action to provide equal access to the use of natriuretic peptides in the diagnosis of acute heart failure across Europe. Bayes-Genis A, Januzzi J, Richards A, Arfsten H, de Boer R, Emdin M, Gonzalez A, Jaarsma T, Jhund P, Mueller C, Nunez J, Rossignol P, Milinkovic I, Rosano G, Coats A, Seferovic P. European Journal of Heart Failure. 2021 Jul 7. doi: 10.1002/ejhf.2293. PMID: 34231321

The influence of sex and body mass index on the association between soluble neprilysin and risk of heart failure hospitalizations. Nunez J, Nunez E, Revuelta-Lopez E, Minana G, Barallat J, Bodi V, Sanchis J, Aimo A, Emdin M, Lupon J, Husser O, Bayes-Genis A. Scientific reports. 2021 Mar 15;11(1):5940. doi: 10.1038/s41598-021-85490-1. PMID: 33723360

A Novel Clinical and Stress Cardiac Magnetic Resonance (C-CMR-10) Score to Predict Long-Term All-Cause Mortality in Patients with Known or Suspected Chronic Coronary Syndrome. Marcos Garcés V, Gavara Doñate J, Monmeneu J, Lopez-Lereu M, Pérez Solé N, Rios Navarro C, De Dios Lluch E, Moratal D, Miñana Escriva G, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. Journal of Clinical Medicine. 2020 Jun 23;9(6):1957. doi: 10.3390/jcm9061957. PMID: 32585832

A randomized controlled trial on carbohydrate antigen 125-guided diuretic treatment versus usual care in patients with acute heart failure and renal dysfunction. Nuñez Villota J, Llacer P, Garcia Blas S, Bonanad Lozano C, Ventura S, Nunez J, Sanchez R, Facila De La Esperanza R, De La Espriella Juan R, Vaquer Santamaria J, Cordero A, Roque M, Chamorro C, Bodí Peris V, Valero Picher E, Santas Olmeda E, Del Carmen Moreno M, Miñana Escriva G, Carratalá Calvo A, Rodriguez Borja E, Mollar Fernandez A, Palau P, Bosch M, Bertomeu-Gonzalez V, Lupon J, Navarro Perez J, Chorro Gascó F, Górriz Teruel J, Sanchis Fores J, Voors A, Bayes-Genis A, IMPROVE-HF Investigators. American Journal of Medicine. 2020 Mar;133(3):370-380.e4. doi: 10.1016/j.amjmed.2019.07.041. PMID: 31422111

Acute kidney injury in heart failure: a population study. Holgado Sánchez J, Lopez Forte C, Fernández Giménez A, Saurí Ferrer M, Uso Talamantes R, Trillo Mata J, Vela Bernal S, Nuñez Villota J, Redón Mas J, Ruiz Hernandez A. Esc Heart Failure. 2020 Apr;7(2):415-422. doi: 10.1002/ehf2.12595. PMID: 32059081

Approaching Sex Differences in Cardiovascular Non-Coding RNA Research. Jusic A, Salgado-Somoza A, PAES MARTÍ A, Stefanizzi F, Martínez Alarcón N, Pinet F, Martelli F, Devaux Y, Robinson E, Novella Del Campo S, On Behalf Of The Eu-Cardiorna Cost Action. International Journal of Molecular Sciences. 2020 Jul 10;21(14):4890. doi: 10.3390/ijms21144890. PMID: 32664454

Beta-blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve-HR trial). Palau P, Seller J, Dominguez E, Gomez I, Ramón Ferrandis J, Sastre Arbona C, De La Espriella Juan R, Santas Olmeda E, Miñana Escriva G, Chorro Gascó F, Ramon Gonzalez-Juanatey J, Nuñez Villota J. Clinical Cardiology. 2020 May;43(5):423-429. doi: 10.1002/clc.23345. PMID: 32073676

Biomarker-guided management in acute heart failure: is there light at the end of the tunnel?. Bayes-Genis A, Emdin M, Nuñez Villota J. European Journal of Heart Failure. 2020 Feb;22(2):276-278. doi: 10.1002/ejhf.1690. PMID: 31833167

CA125 outperforms NT-proBNP in acute heart failure with severe tricuspid regurgitation. Soler Costa M, Miñana Escriva G, Santas Olmeda E, Nuñez Benito E, De La Espriella Juan R, Valero Picher E, Bodí Peris V, Chorro Gascó F, Fernández Cisnal A, D’ascoli G, Marti-Cervera J, Sanchis Fores J, Bayes-Genis A, Nuñez Villota J. International Journal of Cardiology. 2020 Jun 1;308:54-59. doi: 10.1016/j.ijcard.2020.03.027. PMID: 32209267

Chronotropic Incompetence Predicts Distance Walked in Six-Minute Walk Test in Heart Failure with Preserved Ejection Fraction. Palau Sampio P, Dominguez E, Seller J, Sastre Arbona C, Bayes-Genis A, Nuñez Villota J. Journal of Cardiac Failure. 2020 Nov;26(11):1024-1025. doi: 10.1016/j.cardfail.2020.08.011. PMID:32846204

Clinical Features and Natural History of PRKAG2 Variant Cardiac Glycogenosis. Lopez-Sainz A, Dominguez F, Lopes L, Ochoa J, Barriales-Villa R, Climent V, Linschoten M, Tiron C, Chiriatti C, Marques N, Rasmussen T, Espinosa M, Beinart R, Quarta G, Cesar S, Field E, Garcia-Pinilla J, Bilinska Z, Muir A, Roberts A, Santas Olmeda E, Zorio E, Pena-Pena M, Navarro M, Fernandez A, Palomino-Doza J, Azevedo O, Lorenzini M, Garcia-Alvarez M, Bento D, Jensen M, Mendez I, Pezzoli L, Sarquella-Brugada G, Campuzano O, Gonzalez-Lopez E, Mogensen J, Kaski J, Arad M, Brugada R, Asselbergs F, Monserrat L, Olivotto I, Elliott P, Garcia-Pavia P, European Genetic Cardiomyopathies Initiative Investigators. Journal Of The American College of Cardiology. 2020 Jul 14;76(2):186-197. doi: 10.1016/j.jacc.2020.05.029. PMID: 32646569

Clinical profile and 1-year clinical outcomes of super elderly patients admitted with acute heart failure. Lorenzo Hernández M, De La Espriella Juan R, Miñana Escriva G, Núñez Marín G, Santas Olmeda E, Nuñez Benito E, Heredia Cambra R, Mollar Fernandez A, Civera Gómez J, Villaescusa Capilla M, Sastre Arbona C, Conesa Bona A, Bonanad Lozano C, Bayes-Genis A, Nuñez Villota J. European Journal of Internal Medicine. 2020 Nov;81:78-82. doi: 10.1016/j.ejim.2020.05.017. PMID: 32553586

Clinical Role of CA125 in WorseningHeartFailure: A BIOSTAT-CHF Study Subanalysis. NUÑEZ VILLOTA J, Bayes-Genis A, Revuelta-Lopez E, Ter Maaten J, Miñana Escriva G, Barallat J, Cserkoova A, Bodí Peris V, Fernández Cisnal A, Nuñez Benito E, Sanchis Fores J, Lang C, Ng L, Metra M, Voors A. JACC. Heart failure. 2020 May;8(5):386-397. doi: 10.1016/j.jchf.2019.12.005. PMID: 32171764

Comments on the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular disease. Joint Working Group of the SEC and SEEN for the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases, Expert Reviewers for the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases, and the SEC Guidelines Committee. Revista Espanola de Cardiologia (english Ed.). 2020 May;73(5):354-360. doi: 10.1016/j.rec.2019.11.018. PMID: 32205102

Comparison between CA125 and NT-proBNP for evaluating congestion in acute heart failure. Llacer P, Gallardo M, Palau Sampio P, Moreno M, Castillo C, Fernandez C, De La Espriella Juan R, Mollar Fernandez A, Santas Olmeda E, Miñana Escriva G, Manzano L, Bayes-Genis A, Nuñez Villota J. Medicina Clinica. 2020 Sep 17;S0025-7753(20)30571-6. doi: 10.1016/j.medcli.2020.05.063. PMID: 32951882

Differential prognostic impact of type 2 diabetes mellitus in women and men with heart failure with preserved ejection fraction. Palau P, Bertomeu-González V, Sanchis J, Soler M, de la Espriella R, Domínguez E, Santas E, Núñez E, Chorro FJ, Miñana G, Bayés-Genís A, Núñez J. Revista Espanola de Cardiologia (english Ed.). 2020 Jun;73(6):463-470. doi: 10.1016/j.rec.2019.09.002. PMID: 31629690

Drug titration by nursing professionals in heart failure units. Civera JM, Conesa A, Villaescusa A, Nunez J. Revista Espanola de Cardiologia (English Ed.). 2020 Dec 17;S1885-5857(20)30498-9. doi: 10.1016/j.rec.2020.10.013. PMID: 33342715

Early Spot Urinary Sodium and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction. Miñana Escriva G, Llacer P, Sanchis I, Garcia Blas S, Bonanad Lozano C, Ventura S, Sanchez R, De La Espriella Juan R, Bodí Peris V, Facila De La Esperanza R, Mollar Fernandez A, Sanchis Fores J, Bayes-Genis A, Chorro Gascó F, Nuñez Villota J. CardioRenal Medicine. 2020;10(5):362-372. doi: 10.1159/000508178. PMID: 32721973

Effect of insulin on readmission for heart failure following a hospitalization for acute heart failure. Bertomeu-Gonzalez V, Facila L, Palau Sampio P, Miñana Escriva G, Núñez Marín G, De La Espriella Juan R, Santas Olmeda E, Nunez E, Bodí Peris V, Chorro Gascó F, Cordero A, Sanchis Fores J, Lupon J, Bayes-Genis A, Nuñez Villota J. Esc Heart Failure. 2020 Aug 13;7(6):3320-3328. doi: 10.1002/ehf2.12944. PMID: 32790113

Effects of the dual sodium-glucose linked transporter inhibitor, licogliflozin vs placebo or empagliflozin in patients with type 2 diabetes and heart failure. de Boer R, Nuñez Villota J, Kozlovski P, Wang Y, Proot P, Keefe D. British Journal of Clinical Pharmacology. 2020 Jul;86(7):1346-1356. doi: 10.1111/bcp.14248. PMID: 32068914

Efficacy and safety of combined neprilysin and RAS inhibition in heart failure: Let’s leave the doubts behind. De La Espriella Juan R, Bayes-Genis A, Nuñez Villota J. International Journal of Cardiology. 2020 Feb 1;300:198-200. doi: 10.1016/j.ijcard.2019.09.023. PMID: 31748185

Ejection Fraction by Echocardiography for a Selective Use of Magnetic Resonance After Infarction. Marcos-Garces V, Gavara J, Lopez-Lereu M, Monmeneu J, Rios-Navarro C, de Dios E, Perez N, Canoves J, Gonzalez J, Minana G, Nunez J, de la Espriella R, Santas E, Moratal D, Chorro F, Valente F, Lorenzatti D, Rodriguez-Palomares J, Ortiz-Perez J, Bodi V. Circulation. Cardiovascular Imaging. 2020 Dec;13(12):e011491. doi: 10.1161/CIRCIMAGING.120.011491. PMID: 33297764

Factors associated with plasma antigen carbohydrate 125 and amino-terminal pro-B-type natriuretic peptide concentrations in acute heart failure. Miñana Escriva G, De La Espriella Juan R, Mollar Fernandez A, Santas Olmeda E, Nuñez Benito E, Valero Picher E, Bodí Peris V, Chorro Gascó F, Fernández Cisnal A, Marti-Cervera J, Sanchis Fores J, Bayes Genis A, Nuñez Villota J. European Heart Journal-Acute Cardiovascular Care. 2020 Aug;9(5):437-447. doi: 10.1177/2048872620908033. PMID: 32129669

Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study. López Zumel M, Holgado Sánchez J, Ferrandez Izquierdo A, Saurí Ferrer M, Uso Talamantes R, Trillo Mata J, Vela Bernal S, Bea Serrano C, Nuñez Villota J, Ferrer Albero A, Gamez Payá J, Ruiz Hernandez A, Redón Mas J. Journal of Clinical Medicine. 2020 Jun 15;9(6):1869. doi: 10.3390/jcm9061869. PMID: 32549339

Impact of pre-hospital renal function on the detection of acute kidney injury in acute decompensated heart failure. Sanchez-Serna J, Hernandez-Vicente A, Garrido-Bravo I, Pastor-Perez F, Noguera-Velasco J, Casas-Pina T, Rodriguez-Serrano A, Nuñez Villota J, Pascual-Figal D. European Journal of Internal Medicine. 2020 Jul;77:66-72. doi: 10.1016/j.ejim.2020.02.028. PMID: 32127300

Is acute heart failure a distinctive disorder? An analysis from BIOSTAT-CHF. Davison B, Senger S, Sama I, Koch G, Mebazaa A, Dickstein K, Samani N, Metra M, Anker S, Cleland J, Ng L, Mordi I, Zannad F, Filippatos G, Hillege H, Ponikowski P, van Veldhuisen D, Lang C, van der Meer P, Nunez J, Bayes-Genis A, Edwards C, Voors A, Cotter G. European Journal of Heart Failure. 2020 Dec 19. doi: 10.1002/ejhf.2077. PMID: 33340221

Lipoprotein(a) and long-term recurrent infarction after an episode of ST-segment elevation acute myocardial infarction. Miñana Escriva G, Gil-Cayuela C, Bodí Peris V, De La Espriella Juan R, Valero Picher E, Mollar Fernandez A, Marco M, Garcia-Ballester T, Zorio B, Fernández Cisnal A, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Coronary Artery Disease. 2020 Jun;31(4):378-384. doi: 10.1097/MCA.0000000000000852. PMID: 32040026

Long-term LVEF trajectories in patients with type 2 diabetes and heart failure: diabetic cardiomyopathy may underlie functional decline. Julian M, Alonso N, Lupon J, Gavidia-Bovadilla G, Ferrer E, de Antonio M, Lopez-Ayerbe J, Domingo M, Santiago-Vacas E, Zamora E, Codina P, Moliner P, Nuñez Villota J, Santesmases J, Puig-Domingo M, Bayes-Genis A. Cardiovascular Diabetology. 2020 Mar 23;19(1):38. doi: 10.1186/s12933-020-01011-w. PMID: 32293458

Long-term outcome of patients with NSTEMI and nonobstructive coronary arteries by different angiographic subtypes. Garcia-Blas S, Gonzalez D’Gregorio J, Bonanad C, Fernandez-Cisnal A, Valero E, Minana G, Mollar A, Nunez J, Sanchis J. Revista Espanola De Cardiologia (english Ed.). 2020 Dec 18;S1885-5857(20)30488-6. doi: 10.1016/j.rec.2020.10.008. PMID: 33349589

Matrix metalloproteinase-12 cleaved fragment of titin as a predictor of functional capacity in patients with heart failure and preserved ejection fraction. Palau Sampio P, Reese-Petersen A, Dominguez E, Ramón Ferrandis J, Lopez L, Mollar Fernandez A, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Scandinavian Cardiovascular Journal. 2020 Oct 8;1-6. doi: 10.1080/14017431.2020.1831052. PMID: 33030056

Neprilysin inhibition, endorphin dynamics, and early symptomatic improvement in heart failure: a pilot study. Revuelta-Lopez E, Nuñez Villota J, Gastelurrutia P, Cediel G, Januzzi J, Ibrahim N, Emdin M, VanKimmenade R, Pascual-Figal D, Nunez E, Gommans F, Lupon J, Bayes-Genis A. Esc Heart Failure. 2020 Apr;7(2):559-566. doi: 10.1002/ehf2.12607. PMID: 32045114

Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron: The Myocardial-IRON Trial. Nuñez Villota J, Miñana Escriva G, Cardells Beltran I, Palau P, Llacer P, Facila L, Almenar L, Lopez Lereu M, Monmeneu Menadas J, Amiguet Comins M, González D’gregorio J, Serrano Alcalá A, Montagud V, Lopez-Vilella R, Valero Picher E, Garcia Blas S, Bodí Peris V, De La Espriella Juan R, Lupon J, Navarro Perez J, Górriz Teruel J, Sanchis Fores J, Chorro Gascó F, Comin-Colet J, Bayes Genis A, Myocardial-IRON Investigators. Journal of the American Heart Association. 2020 Feb 18;9(4):e014254. doi: 10.1161/JAHA.119.014254. PMID: 32067585

Potential Utility of Cardio-Renal Biomarkers For Prediction and Prognostication of Worsening Renal Function in Acute Heart Failure: Cardio-Renal Biomarkers and WRF in AHF. Horiuchi Y, Wettersten N, van Veldhuisen D, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos M, Cannon C, Mueller G, Birkhahn R, Taub P, Vilke G, Barnett O, McDonald K, Mahon N, Nunez J, Briguori C, Passino C, Maisel A, Murray P. Journal of Cardiac Failure. 2020 Dec 6;S1071-9164(20)31551-7. doi: 10.1016/j.cardfail.2020.11.025. PMID: 33296713

Pulmonary hypertension and right ventricular dysfunction in heart failure: prognosis and 15-year prospective longitudinal trajectories in survivors. Santiago-Vacas E, Lupon J, Gavidia-Bovadilla G, Gual-Capllonch F, de Antonio M, Domingo M, Nuñez Villota J, Zamora E, Teis A, Moliner P, Codina P, Santesmases J, Bayes-Genis A. European Journal of Heart Failure. 2020 Jul;22(7):1214-1225. doi: 10.1002/ejhf.1862. PMID: 32452102

Randomized Comparison of Exercise Intervention Versus Usual Care in Older Adult Patients with Frailty After Acute Myocardial Infarction. Sanchis J, Sastre C, Ruescas A, Ruiz V, Valero E, Bonanad C, Garcia-Blas S, Fernandez-Cisnal A, Gonzalez J, Minana G, Nunez J. American Journal of Medicine. 2020 Oct 24;S0002-9343(20)30904-9. doi: 10.1016/j.amjmed.2020.09.019. PMID: 33228950

Rehospitalization burden and morbidity risk in patients with heart failure with mid-range ejection fraction. Santas Olmeda E, De La Espriella Juan R, Palau P, Miñana Escriva G, Amiguet Comins M, Sanchis Fores J, Lupon J, Bayes Genis A, Chorro Gascó F, Nuñez Villota J. Esc Heart Failure. 2020 Jun;7(3):1007-1014. doi: 10.1002/ehf2.12683. PMID: 32212327

Relation of Low Lymphocyte Count to Frailty and its 11) Usefulness as a Prognostic Biomarker in Patients >65 Years of Age With Acute Coronary Syndrome. Nuñez Villota J, Sastre Arbona C, D’ascoli G, Ruiz Ros V, Bonanad Lozano C, Miñana Escriva G, Valero Picher E, Garcia Blas S, Mollar Fernandez A, Villaescusa Capilla M, Arantzazu Ruescas-Nicolau M, Nuñez Benito E, Formiga F, Chorro Gascó F, Sanchis Fores J. American Journal of Cardiology. 2020 Apr 1;125(7):1033-1038. doi: 10.1016/j.amjcard.2020.01.006. PMID: 31959430

Renal function dynamics following co-administration of sacubitril/valsartan and empagliflozin in patients with heart failure and type 2 diabetes. De La Espriella Juan R, Bayes-Genis A, Morillas H, Bravo R, Vidal V, Nunez E, Santas Olmeda E, Miñana Escriva G, Sanchis Fores J, Facila L, Torres F, Górriz Teruel J, Valle A, Nuñez Villota J. Esc Heart Failure. 2020 Sep 22;7(6):3792-3800. doi: 10.1002/ehf2.12965. PMID: 32964683

Right Ventricular Dysfunction Staging System for Mortality Risk Stratification in Heart Failure with Preserved Ejection Fraction. Santas Olmeda E, De La Espriella Juan R, Chorro Gascó F, Palau P, Miñana Escriva G, Heredia Cambra R, Amiguet Comins M, Merenciano González H, Sanchis Fores J, Lupon J, Bayes Genis A, Nuñez Villota J. Journal of Clinical Medicine. 2020 Mar 18;9(3):831. doi: 10.3390/jcm9030831. PMID: 32197527

Role of PCSK9 in the course of ejection fraction change after ST-segment elevation myocardial infarction: a pilot study. Miñana Escriva G, Nuñez Villota J, Bayes Genis A, Revuelta-Lopez E, Rios Navarro C, Nuñez Benito E, Chorro Gascó F, Lopez Lereu M, Monmeneu Menadas J, Lupon J, Sanchis Fores J, Bodí Peris V. Esc Heart Failure. 2020 Feb;7(1):117-122. doi: 10.1002/ehf2.12533. PMID: 31903686

Sacubitril/Valsartan as Antifibrotic Drug Rejuvenating the Fibrosed HFpEF Heart. Bayes Genis A, Nunez J, Lupon J. Journal of the American College of Cardiology.2020 Aug 4;76(5):515-517. doi: 10.1016/j.jacc.2020.06.016. PMID: 32731929

Serum potassium dynamics during acute heart failure hospitalization. Caravaca Perez P, Gonzalez-Juanatey J, Nuche J, Moran Fernandez L, Lora Pablos D, Alvarez-Garcia J, Bascompte Claret R, Martinez Selles M, Vazquez Garcia R, Martinez Dolz L, Cobo-Marcos M, Pascual Figal D, Crespo-Leiro M, Nunez Villota J, Cinca Cuscullola J, Delgado J. Clinical Research in Cardiology. 2020 Oct 17. doi: 10.1007/s00392-020-01753-3. PMID: 33070219

Sex-differential effect of frailty on long-termmortality in elderly patients after an acute coronary síndrome. Nuñez Villota J, Palau P, Sastre Arbona C, D’ascoli G, Ruiz Ros V, Bonanad Lozano C, Miñana Escriva G, Nunez E, Sanchis Fores J. International Journal of Cardiology. 2020 Mar 1;302:30-33. doi: 10.1016/j.ijcard.2019.12.068. PMID: 31924393

Short-term changes in left and right systolic function following ferric carboxymaltose: a substudy of the Myocardial-IRON trial. Santas Olmeda E, Miñana Escriva G, Cardells I, Palau Sampio P, Llàcer P, Facila De La Esperanza R, Almenar L, López-Lereu M, Monmeneu J, Sanchis Fores J, Maceira A, Bayés-Genís A, Nuñez Villota J, Myocardial-IRON Investigators. Esc Heart Failure. 2020 Oct 11;7(6):4222-4230. doi: 10.1002/ehf2.13053. PMID: 33040491

Short-term prognostic implications of serum and urine neutrophil gelatinase-associated lipocalin in acute heart failure: findings from the AKINESIS study. Wettersten N, Horiuchi Y, van Veldhuisen D, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos M, Cannon C, Mueeller G, Birkhahn R, Taub P, Vilke G, Barnett O, McDonald K, Mahon N, Nuñez Villota J, Briguori C, Passino C, Maisel A, Murray P. European Journal of Heart Failure. 2020 Feb;22(2):251-263. doi: 10.1002/ejhf.1642. PMID: 31863682

Sodium-glucose cotransporter 2 inhibition: towards an indication to treat diabetic kidney disease. Górriz Teruel J, NAVARRO GONZALEZ J, Ortiz A, Vergara A, Nuñez Villota J, Jacobs-Cacha C, Martinez-Castelao A, Jose Soler M. Nephrology, dialysis, transplantation. 2020 Jan 1;35(Suppl 1):i13-i23. doi: 10.1093/ndt/gfz237. PMID: 32003834

sST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction. De La Espriella Juan R, Bayes-Genis A, Revuelta E, Miñana Escriva G, Santas Olmeda E, Llacer P, Garcia Blas S, Fernández Cisnal A, Bonanad Lozano C, Ventura S, Sanchez R, Bodí Peris V, Cordero A, Facila De La Esperanza R, Mollar Fernandez A, Sanchis Fores J, Improve-Hf Investigators, Nuñez Villota J. Journal Of Cardiac Failure. 2020 Oct 8;S1071-9164(20)31473-1. doi: 10.1016/j.cardfail.2020.10.002. PMID: 33038531

Study design of Heart failure Events reduction with Remote Monitoring and eHealth Support (HERMeS). Yun S, Enjuanes C, Calero E, Hidalgo E, Cobo M, Llacer P, Garcia-Pinilla J, Gonzalez-Franco A, Nuñez Villota J, Morales-Rull J, Beltran P, Delso C, Freixa-Pamias R, Moliner P, Corbella X, Comin-Colet J, HERMeS trial investigators group. Esc Heart Failure. 2020 Sep 17;7(6):4448-4457. doi: 10.1002/ehf2.12962. PMID: 32940428

The Effect of Age on Mortality in Patients With COVID-19: A Meta-Analysis With 611,583 Subjects. Bonanad Lozano C, Garcia Blas S, Tarazona-Santabalbina F, Sanchis Fores J, Bertomeu-Gonzalez V, Facila De La Esperanza R, Ariza A, Nuñez Villota J, Cordero A. Journal of the American Medical Directors Association. 2020 Jul;21(7):915-918. doi: 10.1016/j.jamda.2020.05.045. PMID: 32674819

The emerging role of carbohydrate antigen 125 in heart failure. Santas Olmeda E, Palau P, Bayes Genis A, Nuñez Villota J. Biomarkers in Medicine. 2020 Mar;14(4):249-252. doi: 10.2217/bmm-2019-0470. PMID: 32125176

The pre-HFpEF stage: a new entity that requires proper phenotyping for better management. Bayes-Genis A, Pascual-Figal D, Nuñez Villota J. European Journal of Preventive Cardiology. 2020 Feb 4;2047487320902326. doi: 10.1177/2047487320902326. PMID: 32019372

Transitioning from Preclinical to Clinical Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach. Bayes-Genis A, Bisbal F, Nuñez Villota J, Santas Olmeda E, Lupon J, Rossignol P, Paulus W. Journal of Clinical Medicine. 2020 Apr 13;9(4):1110. doi: 10.3390/jcm9041110. PMID: 32294958

Trefoil factor-3 and galectin-4 as new candidates for prognostic biomarkers in ST-segment elevation myocardial infarction. Fernández Cisnal A, García-Blas S, Valero E, Miñana G, Núñez J, Sanchis Forés J. Revista Espanola de Cardiologia (english Ed.). 2020 May;73(5):418-420. doi: 10.1016/j.rec.2019.10.008. PMID: 31761572

Undetectable high-sensitivity troponin in combination with clinical assessment for risk stratification of patients with chest pain and normal troponin at hospital arrival. Sanchis Fores J, Valero Picher E, Garcia Blas S, Barba Serrano E, Pernias Escrig V, Miñana Escriva G, Brasó Aznar J, Fernández Cisnal A, González D’gregorio J, Noceda Bermejo J, Carratalá Calvo A, Chorro Gascó F, Nuñez Villota J, Pickering J. European Heart Journal-Acute Cardiovascular Care. 2020 Sep;9(6):567-575. doi: 10.1177/2048872620907539. PMID: 32067483

Urine: an overlooked biomedium in heart failure?. De La Espriella Juan R, Bayes-Genis A, Nunez E, Nuñez Villota J. Biomarkers in Medicine. 2020 Feb;14(3):165-168. doi: 10.2217/bmm-2019-0433. PMID: 32057256

Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease: A Large Retrospective Registry. Marcos Garcés V, Gavara Doñate J, Monmeneu Menadas J, Lopez-Lereu M, Bosch M, Merlos P, Pérez Solé N, Rios Navarro C, De Dios Lluch E, Bonanad Lozano C, Racugno P, Bellver Navarro A, Ventura Perez B, Aguilar Botella J, Ventura Haro S, Mainar Latorre L, Canoves Femenia J, Pellicer Bañuls M, Moratal Perez D, Miñana Escriva G, Nuñez Villota J, Chorro Gascó F, Bodí Peris V- Jacc-Cardiovascular Imaging. 2020 Aug;13(8):1674-1686. doi: 10.1016/j.jcmg.2020.02.027. PMID: 32682717

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction. Armstrong P, Pieske B, Anstrom K, Ezekowitz J, Hernandez A, Butler J, Lam C, Ponikowski P, Voors A, Jia G, McNulty S, Patel M, Roessig L, Koglin J, O’Connor C, Nuñez Villota J, VICTORIA Study Group. New England Journal of Medicine. 2020 May 14;382(20):1883-1893. doi: 10.1056/NEJMoa1915928. PMID: 32222134

B-type natriuretic peptide trend predicts clinical significance of worsening renal function in acute heart failure. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT, Maisel A. European Journal of Heart Failure. 2019 Dec;21(12):1553-1560. doi: 10.1002/ejhf.1627. PMID: 31769140

Cell-free DNA and Microvascular Damage in ST-segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. Sanchis J1, García-Blas S2, Ortega-Paz L3, Dantas AP3, Rodríguez E4, Abellán L4, Brugaletta S3, Valero E2, Miñana G2, Garabito M3, Corchón Á4, Núñez J2, Carratalá A4, Sabaté M3. Revista Espanola de Cardiologia. 2019 Apr;72(4):317-323. doi: 10.1016/j.rec.2018.03.005. PMID: 29655768

Comorbidity assessment for mortality risk stratification in elderly patients with acute coronary síndrome. Sanchis J, Soler M, Núñez J, Ruiz V, Bonanad C, Formiga F, Valero E, Martínez-Sellés M, Marín F, Ruescas A, García-Blas S, Miñana G, Abu-Assi E, Bueno H, Ariza-Solé A. European Journal of Internal Medicine. 2019 Apr;62:48-53. doi: 10.1016/j.ejim.2019.01.018. PMID: 30711360

Functional tricuspid regurgitation and recurrent admissions in patients with acute heart failure. De la Espriella R, Santas E, Chorro FJ, Miñana G, Soler M, Bodí V, Valero E, Núñez E, Bayés-Genis A, Lupón J, Sanchis J, Núñez J. International Journal of Cardiology. 2019 Sep 15;291:83-88. doi: 10.1016/j.ijcard.2019.03.051. PMID: 30955879

Inspiratory Muscle Training and Functional Electrical Stimulation for Treatment of Heart Failure With Preserved Ejection Fraction: The TRAINING-HF Trial. Palau P, Domínguez E, López L, Ramón JM, Heredia R, González J, Santas E, Bodí V, Miñana G, Valero E, Mollar A, Bertomeu González V, Chorro FJ, Sanchis J, Lupón J, Bayés-Genís A, Núñez J. Revista Espanola de Cardiologia. 2019 Apr;72(4):288-297. doi: 10.1016/j.rec.2018.01.010. PMID: 29551699

International Normalized Ratio and Mortality Risk in Acute Heart Failure and Nonvalvular Atrial Fibrillation Patients Receiving Vitamin K Antagonists. Santas E, Miñana G, Gummel J, Farcasan R, Payá A, Heredia R, Bodí V, Mollar A, Bertomeu-González V, Chorro FJ, Sanchis J, Lupón J, Bayés Genís A, Núñez J. Revista Espanola de Cardiologia. 2019 Aug;72(8):616-624. doi: 10.1016/j.rec.2018.07.010. PMID: 30201288

Invasive Versus Conservative Strategy in Frail Patients With NSTEMI: The MOSCA-FRAIL Clinical Trial Study Design. Sanchis J, Ariza-Solé A, Abu-Assi E, Alegre O, Alfonso F, Barrabés JA, Baz JA, Carol A, Díez Villanueva P, García Del Blanco B, Elízaga J, Fernandez E, García Del Egido A, García Picard J, Gómez Blázquez I, Gómez Hospital JA, Hernández-Antolín R, Llibre C, Marín F, Martí Sánchez D, Martín R, Martínez Sellés M, Miñana G, Morales Gallardo MJ, Núñez J, Pérez de Prado A, Pinar E, Sanmartín M, Sionis A, Villa A, Marrugat J, Bueno H. Revista Espanola de Cardiologia. 2019 Feb;72(2):154-159. doi: 10.1016/j.rec.2018.02.007. PMID: 29525724

Microvascular Obstruction in ST-Segment Elevation Myocardial Infarction: Looking Back to Move Forward. Focus on CMR. Rios-Navarro C, Marcos-Garces V, Bayes-Genis A, Husser O, Nuñez J, Bodi V. Journal of Clinical Medicine. 2019 Oct 28;8(11):1805. doi: 10.3390/jcm8111805. PMID: 31661823

Multicenter Evaluation of Prosthesis Oversizing of the SAPIEN 3 Transcatheter Heart Valve. Impact on Device Failure and New Pacemaker Implantations. Pellegrini C, Kim WK, Holzamer A, Walther T, Mayr NP, Michel J, Rheude T, Nuñez J, Kasel AM, Trenkwalder T, Kaess BM, Joner M, Kastrati A, Schunkert H, Hilker M, Möllmann H, Hengstenberg C, Husser O. Revista Espanola de Cardiologia. 2019 Aug;72(8):641-648. doi: 10.1016/j.rec.2018.06.005. PMID: 30017841

Procedural, Functional and Prognostic Outcomes Following Recanalization of Coronary Chronic Total Occlusions. Results of the Iberian Registry. Amat-Santos IJ, Martin-Yuste V, Fernández-Díaz JA, Martin-Moreiras J, Caballero-Borrego J, Salinas P, Ojeda S, Rivero F, Núñez Villota J, Mohandes M, Dubois D, Bosa Ojeda F, Rumiz E, de la Torre Hernández JM, Jiménez-Mazuecos J, Lacunza J, Tejedor P, Gómez I, Goncalves-Ramirez LR, Rojas P, Sabaté M, Goicolea J, Diego Nieto A, Jiménez-Fernández M, Escaned J, Gonzalo N, Pardo L, Cuesta J, Miñana G, Sanchis J, Rojas S, Millán R, Vaquerizo B, Rodríguez S, Lee DH, Morales FJ, Gutiérrez A, López M, Maristany J, Rondán J, Galeote G, Kabbanni Z, Rodríguez S, Teruel L, Sadaba M, Jurado A, Mainar V, Sánchez-Rubio J, Vinhas H, Fernandes R. Revista Espanola de Cardiologia. 2019 May;72(5):373-382. doi: 10.1016/j.rec.2018.05.020. PMID: 29954721

Prognostic Value of Initial LeftVentricular Remodeling in PatientsWith Reperfused STEMI. Rodriguez-Palomares JF, Gavara J, Ferreira-González I, Valente F, Rios C, Rodríguez-García J, Bonanad C, García Del Blanco B, Miñana G, Mutuberria M, Nuñez J, Barrabés J, Evangelista A, Bodí V, García-Dorado D. JACC-Cardiovascular Imaging. 2019 Dec;12(12):2445-2456. doi: 10.1016/j.jcmg.2019.02.025. PMID: 31202752

Unusual Hydatid Cyst-Like Images Caused by Staphylococcus Lugdunensis Infective Endocarditis. Marcos-Garcés V, Santas E, Pellicer M, Ruiz-Granell R, Chorro FJ. Heart, Lung & Circulation. 2019 Feb;28(2):e16-e18. doi: 10.1016/j.hlc.2018.07.008. PMID: 30126792

Usefulness of Right Ventricular to Pulmonary Circulation Coupling as an Indicator of Risk for Recurrent Admissions in Heart Failure With Preserved Ejection Fraction. Santas E, Palau P, Guazzi M, de la Espriella R, Miñana G, Sanchis J, Bayes-Genís A, Lupón J, Chorro FJ, Núñez J. AMERICAN JOURNAL OF CARDIOLOGY. 2019 Aug 15;124(4):567-572. doi: 10.1016/j.amjcard.2019.05.024. PMID: 31204033

Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary Findings of the Urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic Heart Failure Study (AKINESIS). Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, NuÑez J, Briguori C, Passino C, Maisel A. Journal of Cardiac Failure. 2019 Aug;25(8):654-665. doi: 10.1016/j.cardfail.2019.05.009. PMID: 31128242

Proyectos
Referencia: PI20/00392
Título: Congestión renal e ninsuficiencia cardiaca aguda y síndroma cardiorenal: valoración no invasiva mediante doppler vascular renal
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Julio Núñez Villota
Duración: 2021 – 2023
Presupuesto: 94.834 €

Referencia: PI17/01426
Título: Retirada del Tratamiento Betabloqueante en Pacientes con Insuficiencia Cardíaca con Función Sistólica Preservada e Incompetencia Cronotrópica. Efecto sobre la Capacidad Funcional
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Julio Núñez Villota
Duración: 2018 – 2021
Presupuesto: 127.050 €

Referencia: PI17/01736
Título: Comparación aleatoria entre las estrategias invasivas y conservadoras en pacientes ancianos frágiles con infarto de miocardio sin elevación del segmento ST (MOSCA-FRAIL)
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Gemma Miñana Escrivá
Duración: 2018 – 2021
Presupuesto: 70.180 €

Referencia: PIE15/00013
Título: A multidisciplinary Project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: Vicente Bodí Peris
Duración: 2016 – 2019
Presupuesto: 589.050 €

+ Información
Comments on the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular disease. Joint Working Group of the SEC and SEEN for the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases, Expert Reviewers for the 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases, and the SEC Guidelines Committee. Revista Espanola de Cardiologia (english Ed.). 2020 May;73(5):354-360. doi: 10.1016/j.rec.2019.11.018. PMID: 32205102

Título: Infarto agudo de miocardio sin elevación del segmento ST con coronarias sin lesiones angiográficas significativas: epidemiología, predictores e impacto pronóstico
Doctorando: García Blas, Sergio
Director: Núñez Villota, Julio; Sanchis Fores, Juan
Fecha: 23/07/2020
Universidad: Universitat de València