Research Group on Healthy Aging

Metabolism and Organic Damage Area

To know the molecular mechanisms involved in aging and frailty processes

To develop possible methods to evaluate them

To develop appropriate intervention strategies

To determine an index of quality of life in experimental animals

To develop human imaging biomarkers for the diagnosis of frailty

To study interventions to delay aging and prevent frailty

– Therapy with small extracellular vesicles

– Role of the antiapoptotic gene Bcl-xL

Dra. Consuelo Borrás Blasco
Dra. Consuelo Borrás Blasco

Leading, R4
Established, R3

Juan Gambini Buchón
Consuelo Borrás Blasco    

Recognised/Emerging, R2

Ana Díaz Cuevas
Cristina Mas Bargues
Mar Dromant Jarque
Marta Inglés de la Torre

First Stage, R1

Aurora Román Rodríguez
Jorge Sanz Ros

Collaborating Researchers
Administrative assistant
Effect of familial longevity on frailty and sarcopenia: a case-control study. Belenguer-Varea A, Avellana-Zaragoza JA, Ingles M, Cunha-Perez C, Cuesta-Peredo D, Borras C, Vina J, Tarazona-Santabalbina FJ. International Journal of Environmental Research and Public Health. 2023 Jan 14;20(2):1534. doi: 10.3390/ijerph20021534. PMID: 36674289

Effects of mirror therapy on spasticity and sensory impairment after stroke: systematic review and meta-analysis. Munoz Gomez E, Ingles M, Aguilar Rodriguez M, Sempere Rubio N, Molla Casanova S, Serra Ano P. PM & R. 2023 Feb 14. doi: 10.1002/pmrj.12964. PMID: 36787183

Extracellular vesicles as therapeutic resources in the clinical environment. Sanz Ros J, Mas Bargues C, Romero Garcia N, Huete Acevedo J, Dromant M, Borras C. International Journal of Molecular Sciences. 2023 Jan 25;24(3):2344. doi: 10.3390/ijms24032344. PMID: 36768664

Extracellular Vesicles as Very Important Particles (VIPs) in Aging. Mas Bargues C, Alique M. International Journal of Molecular Sciences. 2023 Feb 20;24(4):4250. doi: 10.3390/ijms24044250. PMID: 36835661

Potential benefits of a single session of remote ischemic preconditioning and walking in sedentary older adults: a pilot study. Munoz-Gomez E, Molla-Casanova S, Sempere-Rubio N, Serra-Ano P, Aguilar-Rodriguez M, Alonso-Aubin DA, Chulvi-Medrano I, Ingles M. International Journal of Environmental Research and Public Health. 2023 Feb 16;20(4):3515. doi: 10.3390/ijerph20043515. PMID: 36834210

The double-edged role of extracellular vesicles in the hallmarks of aging. Romero-Garcia N, Huete-Acevedo J, Mas-Bargues C, Sanz-Ros J, Dromant M, Borras C. Biomolecules. 2023 Jan 13;13(1):165. doi: 10.3390/biom13010165. PMID: 36671550

Author response to Ilgen, U. Alventosa R, Ingles M, Amador S, Mallench L, Rubio N, Ano P. Physical Therapy. 2022 Aug 4;102(8):pzac072. doi: 10.1093/ptj/pzac072. PMID: 35713527

Blood DNA methylation patterns in older adults with evolving dementia. Fernandez Perez R, Alba Linares JJ, Tejedor JR, Fernandez Fernandez A, Calero M, Roman Dominguez A, Borras C, Vina J, Avila J, Medina M, Fernandez Fraga M. The journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Sep 1;77(9):1743-1749. doi: 10.1093/gerona/glac068. PMID: 35299244

Effect of a craniosacral therapy protocol in people with migraine: a randomized controlled trial. Munoz-Gomez E, Ingles M, Aguilar-Rodriguez M, Molla-Casanova S, Sempere-Rubio N, Serra-Ano P, Espi-Lopez G. Journal of Clinical Medicine. 2022 Jan 30;11(3):759. doi: 10.3390/jcm11030759. PMID: 35160211

Effects of foam rolling vs. manual therapy in patients with tension-type headache: a randomized pilot study. Espi-Lopez G, Ingles M, Carrasco-Fernandez J, Serra-Ano P, Copete-Fajardo L, Gonzalez-Gerez J, Saavedra-Hernandez M, Marques-Sule E. Journal of Clinical Medicine. 2022 Mar 23;11(7):1778. doi: 10.3390/jcm11071778. PMID: 35407385

Fourier analysis of collagen bundle orientation in myocardial infarction scars. Marcos-Garces V, Rios-Navarro C, Gomez-Torres F, Gavara J, de Dios E, Diaz A, Minana G, Chorro F, Bodi V, Ruiz-Sauri A. Histochemistry and Cell Biology. 2022 Nov;158(5):471-483. doi: 10.1007/s00418-022-02132-x. PMID: 35948735

Functional transcriptomic analysis of centenarians’ offspring reveals a specific genetic footprint that may explain that they are less frail than age-matched non-centenarians’ offspring. Ingles M, Belenguer-Varea A, Serna E, Mas-Bargues C, Tarazona-Santabalbina F, Borras C, Vina J. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Oct 6;77(10):1931-1938. doi: 10.1093/gerona/glac119. PMID: 35640160

Genistein effect on cognition in prodromal Alzheimer’s disease patients. The GENIAL clinical trial. Vina J, Escudero J, Baquero M, Cebrian M, Carbonell-Asins J, Munoz J, Satorres E, Melendez J, Ferrer-Rebolleda J, Cozar-Santiago M, Santabarbara-Gomez J, Jove M, Pamplona R, Tarazona-Santabalbina F, Borras C. Alzheimers Research & Therapy. 2022 Nov 4;14(1):164. doi: 10.1186/s13195-022-01097-2. PMID: 36329553

Genistein, a tool for geroscience. Bargues C, Borras C, Vina J. Mechanisms of Ageing and Development. 2022 Jun;204:111665. doi: 10.1016/j.mad.2022.111665. PMID: 35307412

Long-lived humans have a unique plasma sphingolipidome. Pradas I, Jove M, Huynh K, Ingles M, Borras C, Mota-Martorell N, Galo-Licona JD, Puig J, Vina J, Meikle PJ, Pamplona R. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Apr 1;77(4):728-735. doi: 10.1093/gerona/glab360. PMID: 34871393

Oxidative stress and inflammation: from mechanisms to therapeutic approaches. Gambini J, Stromsnes K. Biomedicines. 2022 Mar 23;10(4):753. doi: 10.3390/biomedicines10040753. PMID: 35453503

Potential add-on effects of manual therapy techniques in migraine patients: a randomised controlled trial. Munoz-Gomez E, Serra-Ano P, Molla-Casanova S, Sempere-Rubio N, Aguilar-Rodriguez M, Espi-Lopez G, Ingles M. Journal of Clinical Medicine. 2022 Aug 11;11(16):4686. doi: 10.3390/jcm11164686. PMID: 36012924

Recent approaches to determine static and dynamic redox state-related parameters. Mas-Bargues C, Garcia-Dominguez E, Borras C. Antioxidants. 2022 Apr 28;11(5):864. doi: 10.3390/antiox11050864. PMID: 35624728

Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice. Sanz-Ros J, Romero-Garcia N, Mas-Bargues C, Monleon D, Gordevicius J, Brooke RT, Dromant M, Diaz A, Derevyanko A, Guio-Carrion A, Roman-Dominguez A, Ingles M, Blasco MA, Horvath S, Vina J, Borras C. Science Advances. 2022 Oct 21;8(42):eabq2226. doi: 10.1126/sciadv.abq2226. PMID: 36260670

Special issue “Oxidative stress in aging and associated chronic diseases”. Mas-Bargues C, Alique M, Barrús-Ortiz MT, Borrás C, Rodrigues-Díez R. Antioxidants. 2022 Apr 2;11(4):701. doi: 10.3390/antiox11040701. PMID: 35453386

The contribution of extracellular vesicles from senescent endothelial and vascular smooth muscle cells to vascular calcification. Mas-Bargues C, Borras C, Alique M. Frontiers In Cardiovascular Medicine. 2022 Apr 15;9:854726. doi: 10.3389/fcvm.2022.854726. PMID: 35498012

The multimodal action of genistein in Alzheimer’s and other age-related diseases. Mas-Bargues C, Borras C, Vina J. Free Radical Biology & Medicine. 2022 Apr;183:127-137. doi: 10.1016/j.freeradbiomed.2022.03.021. PMID: 35346775

Therapeutic potential of extracellular vesicles in aging and age-related diseases. Sanz-Ros J, Mas-Bargues C, Romero-Garcia N, Huete-Acevedo J, Dromant M, Borras C. International Journal of Molecular Sciences. 2022 Nov 23;23(23):14632. doi: 10.3390/ijms232314632. PMID: 36498960

Transcriptomic profile of epileptic children treated with ketogenic therapies. Ruiz-Herrero J, Olaso-Gonzalez G, Serna E, Canedo-Villarroya E, Correas A, Gambini J, Gomez-Cabrera M, Pedron-Giner C, Vina J. Journal of Integrative Neuroscience. 2022 Jan 28;21(1):31. doi: 10.31083/j.jin2101031. PMID: 35164467

A natural xenogeneic endometrial extracellular matrix hydrogel toward improving current human in vitro models and future in vivo applications. Lopez-Martinez S, Campo H, de Miguel-Gomez L, Faus A, Navarro A, Diaz A, Pellicer A, Ferrero H, Cervello I. Frontiers in Bioengineering and Biotechnology. 2021 Mar 5;9:639688. doi: 10.3389/fbioe.2021.639688. PMID: 33748086

Anti-inflammatory properties of diet: role in healthy aging.Stromsnes K, Correas A, Lehmann J, Gambini J, Olaso-Gonzalez G. Biomedicines. 2021 Jul 30;9(8):922. doi: 10.3390/biomedicines9080922. PMID: 34440125

Attitudes towards learning professional ethics in undergraduate physiotherapy students: A STROBE compliant cross-sectional study. Marques-Sule E, Arnal-Gomez A, Cortes-Amador S, de la Torre M, Hernandez D, Aguilar-Rodriguez M. Nurse Education Today. 2021 Mar;98:104771. doi: 10.1016/j.nedt.2021.104771. PMID: 33529858

Bcl-xL as a Modulator of Senescence and Aging. Mas-Bargues C, Borras C, Vina J. International Journal of Molecular Sciences. 2021 Feb 3;22(4):1527. doi: 10.3390/ijms22041527. PMID: 33546395

Bioengineered endometrial hydrogels with growth factors promote tissue regeneration and restore fertility in murine models. Lopez-Martinez S, Rodriguez-Eguren A, de Miguel-Gomez L, Frances-Herrero E, Faus A, Diaz A, Pellicer A, Ferrero H, Cervello I. Acta Biomaterialia. 2021 Nov;135:113-125. doi: 10.1016/j.actbio.2021.08.025. PMID: 34428563

Biomechanical and viscoelastic properties of the ankle muscles in men with previous history of ankle sprain. Serra-Ano P, Ingles M, Espi-Lopez G, Sempere-Rubio N, Aguilar-Rodriguez M. Journal of Biomechanics. 2021 Jan 22;115:110191. doi: 10.1016/j.jbiomech.2020.110191. PMID: 33385869

Decellularized tracheal prelamination implant: A proposed bilateral double organ technique. Martinez-Hernandez N, Diaz-Cuevas A, Milian-Medina L, Sancho-Tello M, Rosello-Ferrando J, Morcillo-Aixela A, Campo-Canaveral J, Roig-Bataller A, Mata-Roig M. Artificial Organs. 2021 Dec;45(12):1491-1500. doi: 10.1111/aor.14043. PMID: 34310703

Diagnostic performance of muscle echo intensity and fractal dimension for the detection of frailty phenotype. Miron Mombiela R, Vucetic J, Monllor P, Cardenas-Herran JS, Taltavull de la Paz P, Borras C. Ultrasonic Imaging. 2021 Nov;43(6):337-352. doi: 10.1177/01617346211029656. PMID: 34238072

Domestic pig prioritized in one health action against fascioliasis in human endemic areas: Experimental assessment of transmission capacity and epidemiological evaluation of reservoir role. Mas-Coma S, Funatsu IR, Angles R, Buchon P, Mas Bargues C, Artigas P, Valero MA, Bargues MD. One Health. 2021 Apr 16;13:100249. doi: 10.1016/j.onehlt.2021.100249. PMID: 33997234

Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial. Munoz-Gomez E, Ingles M, Serra-Ano P, Espi-Lopez GV. Musculoskeletal Science & Practice. 2021 Apr 30;54:102386. doi: 10.1016/j.msksp.2021.102386. PMID: 33989990

Effectiveness of high-frequency transcranial magnetic stimulation and physical exercise in women with fibromyalgia: a randomized controlled trial. Izquierdo-Alventosa R, Ingles M, Cortes-Amador S, Gimeno-Mallench L, Sempere-Rubio N, Serra-Ano P. Physical Therapy & Rehabilitation Journal. 2021 Oct 1;101(10):pzab159. doi: 10.1093/ptj/pzab159. PMID: 34216139

Effects of balance training on functionality, ankle instability, and dynamic balance outcomes in people with chronic ankle instability: Systematic review and meta-analysis. Molla-Casanova S, Ingles M, Serra-Ano P. Clinical Rehabilitation. 2021 Dec;35(12):1694-1709. doi: 10.1177/02692155211022009. PMID: 34058832

Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain. A randomized controlled trial. Espí López G, Aguilar Rodríguez M, Zarzoso Muñoz M, Serra Año M, Martinez De La Fuente J, Inglés De La Torre M, Marques-Sule E. European Journal of Physical and Rehabilitation Medicine. 2021 Jun;57(3):397-405. doi: 10.23736/S1973-9087.20.06302-9. PMID: 33047944

Estrogen replacement therapy induces antioxidant and longevity-related genes in women after medically induced menopause. Borras C, Ferrando M, Ingles M, Gambini J, Lopez-Grueso R, Edo R, Mas-Bargues C, Pellicer A, Vina J. Oxidative Medicine and Cellular Longevity. 2021 Sep 9;2021:8101615. doi: 10.1155/2021/8101615. PMID: 34539974

Exploring new kingdoms: the role of extracellular vesicles in oxi-inflamm-aging related to cardiorenal syndrome. Mas-Bargues C, Alique M, Barrus-Ortiz M, Borras C, Rodrigues-Diez R. Antioxidants. 2021 Dec 29;11(1):78. doi: 10.3390/antiox11010078. PMID: 35052582

Importance of stem cell culture conditions for their derived extracellular vesicles therapeutic effect. Mas-Bargues C, Borras C. Free Radical Biology & Medicine. 2021 May 20;168:16-24. doi: 10.1016/j.freeradbiomed.2021.03.028. PMID: 33781893

Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus. Borras C, Abdelaziz KM, Diaz A, Gambini J, Jove M, Lopez-Grueso R, Mas-Bargues C, Monleon D, Pamplona R, Vina J. Mechanisms of Ageing and Development. 2021 Dec;200:111596. doi: 10.1016/j.mad.2021.111596. PMID: 34774606

Lipid peroxidation as measured by chromatographic determination of malondialdehyde. Human plasma reference values in health and disease. Mas-Bargues C, Escrivá C, Dromant M, Borrás C, Viña J. Archives of Biochemistry and Biophysics. 2021 Sep 30;709:108941. doi: 10.1016/ PMID: 34097903

Moderate Red Wine Consumption Increases the Expression of Longevity-Associated Genes in Controlled Human Populations and Extends Lifespan in Drosophila melanogaster. Gambini J, Gimeno-Mallench L, Olaso-Gonzalez G, Mastaloudis A, Traber M, Monleon D, Borras C, Vina J. Antioxidants. 2021 Feb 16;10(2):301. doi: 10.3390/antiox10020301. PMID: 33669360

Pharmacological properties of polyphenols: bioavailability, mechanisms of action, and biological effects in in vitro studies, animal models, and humans. Stromsnes K, Lagzdina R, Olaso-Gonzalez G, Gimeno-Mallench L, Gambini J. Biomedicines. 2021 Aug 23;9(8):1074. doi: 10.3390/biomedicines9081074. PMID: 34440278

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates. Duro-Castano A, Borras C, Herranz-Perez V, Blanco-Gandia M, Conejos-Sanchez I, Arminan A, Mas-Bargues C, Ingles M, Minarro J, Rodriguez-Arias M, Garcia-Verdugo J, Vina J, Vicent M. Science Advances. 2021 Mar 26;7(13):eabf9180. doi: 10.1126/sciadv.abf9180. PMID: 33771874

Thermal imaging ruled out as a supplementary assessment in patients with fibromyalgia: a cross-sectional study. Sempere-Rubio N, Aguilar-Rodriguez M, Ingles M, Izquierdo-Alventosa R, Serra-Ano P. PLoS One. 2021 Jun 16;16(6):e0253281. doi: 10.1371/journal.pone.0253281. PMID: 34133467

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. NCD Risk Factor Collaboration. Lancet. 2021 Sep 11;398(10304):957-980. doi: 10.1016/S0140-6736(21)01330-1. PMID: 34450083

Assessment of Functional Activities in Individuals with Parkinson’s Disease Using a Simple and Reliable Smartphone-Based Procedure. Serra Año M, Pedrero-Sanchez J, Inglés De La Torre M, Aguilar-Rodriguez M, Vargas-Villanueva I, Lopez-Pascual J. International Journal of Environmental Research and Public Health. 2020 Jun 9;17(11):4123. doi: 10.3390/ijerph17114123. PMID: 32527031

BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians. Borras Blasco C, Mas Bargues C, Roman-Dominguez A, Sanz Ros J, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. International Journal of Molecular Sciences. 2020 Jan 9;21(2):418. doi: 10.3390/ijms21020418. PMID: 31936510

Centenarians: An excellent example of resilience for successful ageing. Borras Blasco C, Inglés De La Torre M, Mas Bargues C, Dromant M, Sanz Ros J, Roman-Dominguez A, Gimeno Mallench L, Gambini Buchon J, Viña Ribes J. Mechanisms of Ageing and Development. 2020 Mar;186:111199. doi: 10.1016/j.mad.2019.111199. PMID: 31899226

Comparative study of the effectiveness of a low-pressure hyperbaric oxygen treatment and physical exercise in women with fibromyalgia: randomized clinical trial. Izquierdo-Alventosa R, Inglés De La Torre M, Cortes-Amador S, Gimeno Mallench L, Sempere Rubio N, Chirivella J, Serra Año M. Therapeutic advances in musculoskeletal disease. 2020 Jun 24;12:1759720X20930493. doi: 10.1177/1759720X20930493. PMID: 32636943

Development and Long-Term Follow-Up of an Experimental Model of Myocardial Infarction in Rabbits. Genovés Martínez P, Arias Mutis Ó, Parra Giraldo G, Such Miquel L, Zarzoso Muñoz M, Del Canto Serrano I, Soler Lopez C, Diaz Cuevas A, Blanch Torres E, Alberola Aguilar A, Such Belenguer L, Chorro Gascó F. Animals. 2020 Sep 4;10(9):1576. doi: 10.3390/ani10091576. PMID: 32899601

Donkey fascioliasis within a one health control action: transmission capacity, field epidemiology, and reservoir role in a human hyperendemic área. Mas-Coma S, Buchon P, Funatsu I, Angles R, Mas Bargues C, Artigas P, Valero M, Bargues M. Frontiers in Veterinary Science. 2020 Nov 5;7:591384. doi: 10.3389/fvets.2020.591384. PMID: 33251272

Effect of manual therapy and splint therapy in people with temporomandibular disorders: a preliminary study. Espí López G, Arnal-Gomez A, Cuerda Del Pino A, Benavent-Corai J, Serra Año M, Inglés De La Torre M. Journal of Clinical Medicine. 2020 Jul 28;9(8):2411. doi: 10.3390/jcm9082411. PMID: 32731453

Extracellular vesicles and redox modulation in aging. Borras Blasco C, Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. Free Radical Biology and Medicine. 2020 Mar;149:44-50. doi: 10.1016/j.freeradbiomed.2019.11.032. PMID: 31783096

Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation. Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Viña Ribes J, Borras Blasco C. Biomolecules. 2020 Jun 25;10(6):957. doi: 10.3390/biom10060957. PMID: 32630449

Garcinoic acid prevents beta-amyloid (Abeta) deposition in the mouse brain. Marinelli R, Torquato P, Bartolini D, Mas Bargues C, Bellezza G, Gioiello A, Borras Blasco C, De Luca A, Fallarino F, Sebastiani B, Mani S, Sidoni A, Viña Ribes J, Leri M, Bucciantini M, Nardiello P, Casamenti F, Galli F. Journal of biological chemistry. 2020 Aug 14;295(33):11866-11876. doi: 10.1074/jbc.RA120.013303. PMID: 32616652

Low-Intensity Physical Exercise Improves Pain Catastrophizing and Other Psychological and Physical Aspects in Women with Fibromyalgia: A Randomized Controlled Trial. Izquierdo-Alventosa R, Inglés De La Torre M, Cortes-Amador S, Gimeno Mallench L, Chirivella-Garrido J, Kropotov J, Serra Año M. International Journal of Environmental Research and Public Health. 2020 May 21;17(10):3634. doi: 10.3390/ijerph17103634. PMID: 32455853

Methionine transsulfuration pathway is upregulated in long-lived humans. Mota-Martorell N, Mariona J, Consuelo B, Rebeca B, Elia O, Joaquim S, Rosanna C, Irene P, Galo-Licona J, Josep P, Jose V, Reinald P. Free Radical Biology & Medicine. 2020 Nov 30;162:38-52. doi: 10.1016/j.freeradbiomed.2020.11.026. PMID: 33271279

Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis (vol 146, pg 284, 2019). Gonzalez-Miguel J, Valero M, Reguera-Gomez M, Mas Bargues C, Bargues M, Simon-Martin F, Mas-Coma S. Parasitology. 2020 May;147(6):729. doi: 10.1017/S0031182020000268. PMID: 32052717

Oxidative stress and exceptional human longevity: Systematic review. Belenguer-Varea A, Tarazona-Santabalbina F, Avellana-Zaragoza J, Martinez-Reig M, Mas Bargues C, Inglés De La Torre M. Free Radical Biology and Medicine. 2020 Mar;149:51-63. doi: 10.1016/j.freeradbiomed.2019.09.019. PMID: 31550529

Paths of the cervical instantaneous axis of rotation during active movements-patterns and reliability.Venegas W, Inglés De La Torre M, Page A, Serra-Ano P. Medical & Biological Engineering & Computing. 2020 May;58(5):1147-1157. doi: 10.1007/s11517-020-02153-5. PMID: 32193862

Protective Effects of Polyphenols Present in Mediterranean Diet on Endothelial Dysfunction. Stromsnes K, Mas-Bargues C, Gambini J, Gimeno-Mallench L. Oxidative medicine and cellular longevity. 2020 Aug 6;2020:2097096. doi: 10.1155/2020/2097096. PMID: 32831990

Relationship between Diet, Microbiota, and Healthy Aging. Sanchez-Morate E, Gimeno Mallench L, Stromsnes K, Sanz Ros J, Roman-Dominguez A, Parejo-Pedrajas S, Inglés De La Torre M, Olaso González G, Gambini Buchon J, Mas Bargues C. Biomedicines. 2020 Aug 14;8(8):287. doi: 10.3390/biomedicines8080287. PMID: 32823858

Special issue: Redox Signalling in Health and Disease. Borras Blasco C, Viña Ribes J. Free Radical Biology And Medicine. 2020 Mar;149:1. doi: 10.1016/j.freeradbiomed.2020.02.009. PMID: 32061736

The Relationship between Diet and Frailty in Aging. Gimeno Mallench L, Sanchez-Morate E, Parejo-Pedrajas S, Mas Bargues C, Inglés De La Torre M, Sanz Ros J, Roman-Dominguez A, Olaso González G, Stromsnes K, Gambini Buchon J. Endocrine, Metabolic & Immune Disorders Drug Targets. 2020;20(9):1373-1382. doi: 10.2174/1871530320666200513083212. PMID: 32400339

Reference: AC20/00026
Title: Combining vitamin E-functionalized CHOcolate with physical exercise to reduce the risK of protein energy malnutrition in pre-dementia AGEd people. ERA-HDHL Call for Joint Transnational Research Proposals on Development of targeted nutrition for prevention of undernutrition for older adults (PREVNUT)
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: José Viña Ribes
Duration: 2021 – 2023
Total budget: 169.098 €
Reference: PID2020-113839RB-I00
Title: Efecto del tratamiento con vesículas extracelulares de células madre de grasa de ratones jóvenes sobre parámetros de envejecimiento y fragilidad en ratones de edad avanzada
Funding body: Ministerio de Ciencia e Innovación
Principal Investigator: Consuelo Borrás Blasco
Duration: 2021 – 2024
Total budget: 181.500 €
Reference: GV/2018/067
Title: Estudio de posibles huellas genéticas de envejecimiento saludable en descendientes de centenarios
Funding body: Conselleria de Educación, Cultura y Deporte
Principal Investigator: Marta Inglés de la Torre
Duration: 2018 – 2019
Total budget: 12.040 €
Reference: INTIMIC-085
Title: GUTMOM: Maternal obesity and cognitive dysfunction in the offspring: cause-effect role of the GUT MicrobiOMe and early dietary prevention
Funding body: European Commission. JPI HDHL
Principal Investigator: Patricia Lozzo
Duration: 2017 – 2020
Total budget: 778.240 €
Reference: PCIN-2017-117
Title: Obesidad materna y disfunción cognitiva en la descendencia: papel causa-efecto de la microbiota intestinal y prevención dietética temprana
Funding body: Ministerio de Economía y Competitividad
Principal Investigator: Consuelo Borrás Blasco
Duration: 2017 – 2022
Total budget: 143.000 €
Reference: COST Action CA15203 MITOEAGLE
Title: Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Funding body: European Commission
Principal Investigator: Erich Gnaiger
Duration: 2016 – 2020
Total budget:
+ Info
Title: Transcriptómica en centenarios: un ejemplo de envejecimiento satisfactorio
Doctoral candidate: Dromant Jarque, Mar
Director(s): Inglés De La Torre, Marta; Borrás Blasco, Consuelo; Viña Ribes, José
Date of the defense: 21/12/2021
University: Universitat de València

Title: Eficacia de la terapia manual en pacientes con migraña
Doctoral candidate: Muñoz Gómez, Elena
Director(s): Inglés De La Torre, Marta; Espí López, Gemma Victoria
Date of the defense: 23/04/2021
University: Universitat de València

Title: Efecto de la activación del receptor PPARy/RxR como posible tratamiento de la enfermedad de Alzheimer. Papel de la genisteína
Doctoral candidate: Muñoz Cebriá, José Enrique
Director(s): Viña, José; Borrás, Consuelo; Gambini, Juan
Date of the defense: 01/07/2020
University: Universitat de València

Title: Development of an ultrasound-based muscle texture analysis as a potential imaging biomarker for frailty phenotype
Doctoral candidate: Mirón Mombiela, Rebeca
Director(s): Borrás Blasco, Consuelo; Forner Giner, Juana
Date of the defense: 28/01/2019
University: Universitat de València