Grupo de investigación en envejecimiento y ejercicio físico

Área de Metabolismo y Daño Orgánico

Medicina regenerativa en el envejecimiento

Identificación del entrenamiento físico como fármaco para tratar la fragilidad asociada a la edad

Probar que G6PD protege del daño oxidativo y mejora la vida útil en ratones

Estrés reductor: un nuevo concepto en la enfermedad de Alzheimer

Coordinador
Dr. José Viña Ribes
jose.vina@uv.es

INVESTIGADORES
R4 Senior

José Viña Ribes    

R3 Consolidado

Consolación García Lucerga
Eva Serna García

R2 Novel / Emergente

José Viña Almunia
Paloma Monllor Taltavull
Ana Lloret Alcañiz    

R1 Predoctoral

Ángela García Correas

STAFF
Colaborador/a
Enfermero/a
Técnico/a
Apoyo

Cristina Amézcua García

Publicaciones
Adolescent binge-ethanol accelerates cognitive impairment and beta-amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice. Carlos Ledesma J, Rodriguez-Arias M, Gavito A, Sanchez-Perez A, Viña Ribes J, Medina Vera D, Rodriguez De Fonseca F, Minarro J. Addiction Biology. 2021 Jan;26(1):e12883. doi: 10.1111/adb.12883. PMID: 32043730

Bcl-xL as a Modulator of Senescence and Aging. Mas-Bargues C, Borras C, Vina J. International Journal of Molecular Sciences. 2021 Feb 3;22(4):1527. doi: 10.3390/ijms22041527. PMID: 33546395

Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers. Garcia-Gimenez J, Mena-Molla S, Tarazona-Santabalbina F, Vina J, Gomez-Cabrera M, Pallardo F. International Journal of Environmental Research and Public Health. 2021 Feb 15;18(4):1883. doi: 10.3390/ijerph18041883. PMID: 33672064

Moderate Red Wine Consumption Increases the Expression of Longevity-Associated Genes in Controlled Human Populations and Extends Lifespan in Drosophila melanogaster. Gambini J, Gimeno-Mallench L, Olaso-Gonzalez G, Mastaloudis A, Traber M, Monleon D, Borras C, Vina J. Antioxidants. 2021 Feb 16;10(2):301. doi: 10.3390/antiox10020301. PMID: 33669360

Overexpression of glucose 6 phosphate dehydrogenase preserves mouse pancreatic beta cells function until late in life. De la Rosa A, Gomez-Cabrera M, Vinue A, Gonzalez-Navarro H, Sanchez-Andres J, Vina J. Free radical biology & medicine. 2021 Feb 20;164:149-153. doi: 10.1016/j.freeradbiomed.2020.12.439. PMID: 33418115

Serum Levels of Clusterin, PKR, and RAGE Correlate with Amyloid Burden in Alzheimer’s Disease. Monllor P, Giraldo E, Badia M, de la Asuncion J, Alonso M, Lloret A, Vina J. Journal of Alzheimer’s disease. 2021 Feb 20. doi: 10.3233/JAD-201443. PMID: 33646167

A Novel Micronutrient Blend Mimics Calorie Restriction Transcriptomics in Multiple Tissues of Mice and Increases Lifespan and Mobility in C. elegans. Serna García E, Mastaloudis A, Martorell P, Wood S, Hester S, Bartlett M, Prolla T, Viña Ribes J. Nutrients. 2020 Feb 14;12(2):486. doi: 10.3390/nu12020486. PMID: 32075050

Anti-Aging Physiological Roles of Aryl Hydrocarbon Receptor and Its Dietary Regulators. Serna E, Cespedes C, Vina J. International Journal of Molecular Sciences. 2020 Dec 31;22(1):374. doi: 10.3390/ijms22010374. PMID: 33396477

BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians. Borras Blasco C, Mas Bargues C, Roman-Dominguez A, Sanz Ros J, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. International Journal of Molecular Sciences. 2020 Jan 9;21(2):418. doi: 10.3390/ijms21020418. PMID: 31936510

Centenarians: An excellent example of resilience for successful ageing. Borras Blasco C, Inglés De La Torre M, Mas Bargues C, Dromant M, Sanz Ros J, Roman-Dominguez A, Gimeno Mallench L, Gambini Buchon J, Viña Ribes J. Mechanisms of Ageing and Development. 2020 Mar;186:111199. doi: 10.1016/j.mad.2019.111199. PMID: 31899226

Early reductive stress and late onset overexpression of antioxidant enzymes in experimental myocardial infarction. Carretero Martínez A, Gomez Cabrera M, Rios Navarro C, Salvador Pascual A, Bodí Peris V, Viña Ribes J. Free Radical Research. 2020 Mar;54(2-3):173-184. doi: 10.1080/10715762.2020.1735632. PMID: 32103692

Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning. Arc-Chagnaud C, Py G, Fovet T, Roumanille R, Demangel R, Pagano A, Delobel P, Blanc S, Jasmin B, Blottner D, Salanova M, Gomez Cabrera M, Viña Ribes J, Brioche T, Chopard A. Frontiers in Physiology. 2020 Feb 12;11:71. doi: 10.3389/fphys.2020.00071. PMID: 32116779

Extracellular vesicles and redox modulation in aging. Borras Blasco C, Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. Free Radical Biology and Medicine. 2020 Mar;149:44-50. doi: 10.1016/j.freeradbiomed.2019.11.032. PMID: 31783096

Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation. Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Viña Ribes J, Borras Blasco C. Biomolecules. 2020 Jun 25;10(6):957. doi: 10.3390/biom10060957. PMID: 32630449

Garcinoic acid prevents beta-amyloid (Abeta) deposition in the mouse brain. Marinelli R, Torquato P, Bartolini D, Mas Bargues C, Bellezza G, Gioiello A, Borras Blasco C, De Luca A, Fallarino F, Sebastiani B, Mani S, Sidoni A, Viña Ribes J, Leri M, Bucciantini M, Nardiello P, Casamenti F, Galli F. Journal of biological chemistry. 2020 Aug 14;295(33):11866-11876. doi: 10.1074/jbc.RA120.013303. PMID: 32616652

Hippocampal oscillatory dynamics and sleep atonia are altered in an animal model of fibromyalgia: implications in the search for biomarkers. Blasco-Serra A, Alfosea-Cuadrado G, Cervera-Ferri A, Gonzalez-Soler E, Lloret Alcañiz A, Martinez-Ricos J, Teruel-Marti V, Valverde-Navarro A. Journal of Comparative Neurology. 2020 Jun;528(8):1367-1391. doi: 10.1002/cne.24829. PMID: 31785155

Increased basal antioxidant levels in RCAN1 – deficient mice lowers oxidative injury after acute paraquat insult. Lloret Alcañiz A, Monllor Taltavull P, Fuchsberger T, Giraldo Reboloso E, Perluigi M, Viña Ribes J. Free Radical Research. 2020 Jun;54(6):442-454. doi: 10.1080/10715762.2020.1798002. PMID:32686528

Influence of occlusal loading on peri-implant inflammatory cytokines in crevicular fluid: a prospective longitudinal study. Viña Almunia J, Pellicer-Chover H, Garcia-Mira B, Romero-Millan J, Penarrocha-Oltra D, Penarrocha-Diago M. International Journal Of Implant Dentistry. 2020 Oct 28;6(1):71. doi: 10.1186/s40729-020-00262-2. PMID: 33111201

Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: an experimental study in rabbits. Favero G, Vina-Almunia J, Carda C, de Llano J, Garcia-Mira B, Soto-Penaloza D, Penarrocha-Diago M, Botticelli D. International Journal of Implant Dentistry. 2020 Mar 4;6(1):9. doi: 10.1186/s40729-020-0206-2. PMID: 32128632

Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker. Lloret M, Cervera-Ferri A, Nepomuceno M, Monllor P, Esteve D, Lloret Alcañiz A. International Journal of Molecular Sciences. 2020 Feb 10;21(3):1168. doi: 10.3390/ijms21031168. PMID: 32050587

Methionine transsulfuration pathway is upregulated in long-lived humans. Mota-Martorell N, Mariona J, Consuelo B, Rebeca B, Elia O, Joaquim S, Rosanna C, Irene P, Galo-Licona J, Josep P, Jose V, Reinald P. Free Radical Biology & Medicine. 2020 Nov 30;162:38-52. doi: 10.1016/j.freeradbiomed.2020.11.026. PMID: 33271279

Modulating Oxidant Levels to Promote Healthy Aging. Viña Ribes J, Olaso González G, Arc-Chagnaud C, De La Rosa González A, Gomez Cabrera M. Antioxidants & Redox Signaling. 2020 Sep 10;33(8):570-579. doi: 10.1089/ars.2020.8036. PMID: 32008355

Multicomponent Exercise Training Combined with Nutritional Counselling Improves Physical Function, Biochemical and Anthropometric Profiles in Obese Children: A Pilot Study. Cordellat Marzal A, Padilla Lopez B, Grattarola P, Garcia Lucerga C, Crehuá Gaudiza E, Nuñez Gomez F, Martinez Costa C, Blasco Lafarga M. Nutrients. 2020 Sep 6;12(9):2723. doi: 10.3390/nu12092723. PMID: 32899955

Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies. Cenini G, Lloret Alcañiz A, Cascella R. Oxidative Medicine and Cellular Longevity. 2020 May 4;2020:1270256. doi: 10.1155/2020/1270256. PMID: 32454930

Physical exercise in the prevention and treatment of Alzheimer’s disease. De La Rosa González A, Olaso Gonzalez G, Arc-Chagnaud C, Millán F, Salvador Pascual A, Garcia Lucerga C, Blasco Lafarga M, Garcia Dominguez E, Carretero Martínez A, Correas A, Viña Ribes J, Gomez Cabrera M. Journal of Sport and Health Science. 2020 Sep;9(5):394-404. doi: 10.1016/j.jshs.2020.01.004. PMID: 32780691

Redox modulation of muscle mass and function. Gomez Cabrera M, Arc-Chagnaud C, Salvador Pascual A, Brioche T, Chopard A, Olaso González G, Viña Ribes J. Redox Biology. 2020 Aug;35:101531. doi: 10.1016/j.redox.2020.101531. PMID: 32371010

Relationship between Diet, Microbiota, and Healthy Aging. Sanchez-Morate E, Gimeno Mallench L, Stromsnes K, Sanz Ros J, Roman-Dominguez A, Parejo-Pedrajas S, Inglés De La Torre M, Olaso González G, Gambini Buchon J, Mas Bargues C. Biomedicines. 2020 Aug 14;8(8):287. doi: 10.3390/biomedicines8080287. PMID: 32823858

Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. Ruiz J, Dent E, Morley J, Merchant R, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer J, Cesari M, Chen L, Cruz-Jentoft A, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster J, Rodriguez-Manas L, Rolland Y, Sanford A, Sinclair A, Viña Ribes J, Waters D, Won C, Woo J, Vellas B. Journal of Nutrition Health & Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3. PMID: 33155616

Special issue: Exercise redox biology from health to performance. Gomez Cabrera M, Viña Ribes J, Olaso González G. Redox Biology. 2020 Aug;35:101584. doi: 10.1016/j.redox.2020.101584. PMID:32448750

Special issue: Redox Signalling in Health and Disease. Borras Blasco C, Viña Ribes J. Free Radical Biology And Medicine. 2020 Mar;149:1. doi: 10.1016/j.freeradbiomed.2020.02.009. PMID: 32061736

The Status of EGFR Modulates the Effect of miRNA-200c on ZEB1 Expression and Cell Migration in Glioblastoma Cells. Munoz-Hidalgo L, San-Miguel T, Megias J, Serna E, Calabuig-Farinas S, Monleon D, Gil-Benso R, Cerda-Nicolas M, Lopez-Gines C. International Journal of Molecular Sciences. 2020 Dec 31;22(1):368. doi: 10.3390/ijms22010368. PMID: 33396457

Transcriptomic identification of miR-205 target genes potentially involved in metastasis and survival of cutaneous malignant melanoma. Sanchez Sendra B, Serna García E, Navarro Cerveró L, González Muñoz J, Portero Trigo J, Ramos Jarero A, Murgui Faubel A, Monteagudo Castro C. Scientific Reports. 2020 Mar 16;10(1):4771. doi: 10.1038/s41598-020-61637-4. PMID: 32179834

A New Functional Classification Based on Frailty and Disability Stratifies the Risk for Mortality Among Older Adults: The FRADEA Study. Hoogendijk EO, Romero L, Sánchez-Jurado PM, Flores Ruano T, Viña J, Rodríguez-Mañas L, Abizanda P. Journal of the American Medical Directors Association. 2019 Sep;20(9):1105-1110. doi: 10.1016/j.jamda.2019.01.129. PMID: 30853426

Beneficial Effects of Inspiratory Muscle Training Combined With Multicomponent Training in Elderly Active Women. Roldan A, Cordellat A, Monteagudo P, Garcia Lucerga C, Blasco-Lafarga N, Gomez Cabrera M, Blasco-Lafarga C. Research Quarterly for Exercise and Sport. 2019 Dec;90(4):547-554. doi: 10.1080/02701367.2019.1633009. PMID: 31397649

Centenarians overexpress pluripotency-related genes. Inglés M, Mas-Bargues C, Berna-Erro A, Matheu A, Sanchís P, Avellana JA, Borrás C, Viña J. Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 2019 Aug 16;74(9):1391-1395. doi: 10.1093/gerona/gly168. PMID: 30052797

Copenhagen Consensus statement 2019: physical activity and ageing. Bangsbo J, Blackwell J, Boraxbekk CJ, Caserotti P, Dela F, Evans AB, Jespersen AP, Gliemann L, Kramer AF, Lundbye-Jensen J, Mortensen EL, Lassen AJ, Gow AJ, Harridge SDR, Hellsten Y, Kjaer M, Kujala UM, Rhodes RE, Pike ECJ, Skinner T, Skovgaard T, Troelsen J, Tulle E, Tully MA, van Uffelen JGZ, Viña J. British Journal of Sports Medicine. 2019 Jul;53(14):856-858. doi: 10.1136/bjsports-2018-100451. PMID: 30792257

Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?. Parra-Llorca A, Gormaz M, Sánchez-Illana Á, Piñeiro-Ramos JD, Collado MC, Serna E, Cernada M, Nuñez-Ramiro A, Ramón-Beltrán A, Oger C, Galano JM, Vigor C, Durand T, Kuligowski J, Vento M. Antioxidants & Redox Signaling. 2019 Oct 10;31(11):791-799. doi: 10.1089/ars.2019.7821. PMID: 31250657

Effect of Kinesio taping on clinical symptoms in people with fibromyalgia: A randomized clinical trial. Espí-López GV, Inglés M, Ferrando AC, Serra-Añó P. Journal of Back And Musculoskeletal Rehabilitation. 2019;32(4):561-567. doi: 10.3233/BMR-171100. PMID: 30530959

Effect on osseointegration of two implant macro-designs: A histomorphometric analysis of bicortically installed implants in different topographic sites of rabbit’s tibiae. Soto-Peñaloza D, Caneva M, Viña-Almunia J, Martin-de-Llano JJ, García-Mira B, Peñarrocha-Oltra D, Botticelli D, Peñarrocha-Diago M. Medicina Oral Patologia Oral y Cirugia Bucal. 2019 Jul 1;24(4):e502-e510. doi: 10.4317/medoral.22825. PMID: 31232382

Effectiveness of myofascial release after breast cancer surgery in women undergoing conservative surgery and radiotherapy: a randomized controlled trial. Serra-Añó P, Inglés M, Bou-Catalá C, Iraola-Lliso A, Espí-López GV. Supportive Care in Cancer. 2019 Jul;27(7):2633-2641. doi: 10.1007/s00520-018-4544-z. PMID: 30470892

Effects of Taping and Balance Exercises on Knee and Lower Extremity Function in Amateur Soccer Players: A Randomized Controlled Trial. Espí-López GV, Serra-Añó P, Cobo-Pascual D, Zarzoso M, Suso-Martí L, Cuenca-Martínez F, Inglés M. Journal of Sport Rehabilitation. 2019 May 16:1-25. doi: 10.1123/jsr.2018-0452. PMID: 31094640

Exceptional human longevity is associated with a specific plasma phenotype of ether lipids. Pradas I, Jové M, Huynh K, Puig J, Ingles M, Borras C, Viña J, Meikle PJ, Pamplona R. Redox Biology. 2019 Feb;21:101127. doi: 10.1016/j.redox.2019.101127. PMID: 30711699

Exercise and probiotics attenuate the development of Alzheimer’s disease in transgenic mice: Role of microbiome. Abraham D, Feher J, Scuderi GL, Szabo D, Dobolyi A, Cservenak M, Juhasz J, Ligeti B, Pongor S, Gomez-Cabrera MC, Vina J, Higuchi M, Suzuki K, Boldogh I, Radak Z. Experimental Gerontology. 2019 Jan;115:122-131. doi: 10.1016/j.exger.2018.12.005. PMID: 30529024

Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo. Yeo D, Kang C, Gomez-Cabrera MC, Vina J, Ji LL. Free Radical Biology & Medicine.2019 Jan;130:361-368. doi: 10.1016/j.freeradbiomed.2018.10.456. PMID: 30395971

Long-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B. De la Rosa A, Solana E, Corpas R, Bartrés-Faz D, Pallàs M, Vina J, Sanfeliu C, Gomez-Cabrera MC. Scientific Reports. 2019 Mar 4;9(1):3337. doi: 10.1038/s41598-019-40040-8. PMID: 30833610

Mobility assessment in people with Alzheimer disease using smartphone sensors. Serra-Añó P, Pedrero-Sánchez JF, Hurtado-Abellán J, Inglés M, Espí-López GV, López-Pascual J. Journal of NeuroEngineering and Rehabilitation. 2019 Aug 14;16(1):103. doi: 10.1186/s12984-019-0576-y. PMID: 31412893

Moderate Exercise Improves Experimental Cancer Cachexia by Modulating the Redox Homeostasis. Ballarò R, Penna F, Pin F, Gómez-Cabrera MC, Viña J, Costelli P. Cancers. 2019 Feb 28;11(3):285. doi: 10.3390/cancers11030285. PMID: 30823492

Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis. González-Miguel J, Valero MA, Reguera-Gomez M, Mas-Bargues C, Bargues MD, Simón F, Mas-Coma S. Parasitology. 2019 Mar;146(3):284-298. doi: 10.1017/S0031182018001464. PMID: 30246668

Obesity as a Risk Factor for Alzheimer’s Disease: Implication of Leptin and Glutamate. Lloret A, Monllor P, Esteve D, Cervera-Ferri A, Lloret MA. Frontiers in Neuroscience. 2019 May 22;13:508. doi: 10.3389/fnins.2019.00508. PMID: 31191220

Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View. Cenini G, Lloret A, Cascella R. Oxidative Medicine and Cellular Longevity. 2019 May 9;2019:2105607. doi: 10.1155/2019/2105607. PMID: 31210837

Redox lipidomics to better understand brain aging and function. Pamplona R, Borras C, Jové M, Pradas I, Ferrer I, Viña J. Free radical biology & medicine. 2019 Nov 20;144:310-321. doi: 10.1016/j.freeradbiomed.2019.03.016. PMID: 30898667

Relation Between Genetic Factors and Frailty in Older Adults. Inglés M, Mas-Bargues C, Gimeno-Mallench L, Cruz-Guerrero R, García-García FJ, Gambini J, Borrás C, Rodríguez-Mañas L, Viña J. Journal of the American Medical Directors Association. 2019 Nov;20(11):1451-1457. doi: 10.1016/j.jamda.2019.03.011. PMID: 31078485

Relation between the distance from the cementoenamel junction to the bone crest and the thickness of the facial bone in anterior maxillary teeth: A cross-sectional tomographic study. Rojo-Sanchis J, Peñarrocha-Oltra D, Peñarrocha-Diago M, Zaragozí-Alonso R, Viña-Almunia J. Medicina Oral Patologia Oral y Cirugia Bucal. 2019 May 1;24(3):e409-e415. doi: 10.4317/medoral.22802

Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine. Mas-Bargues C, Sanz-Ros J, Román-Domínguez A, Inglés M, Gimeno-Mallench L, El Alami M, Viña-Almunia J, Gambini J, Viña J, Borrás C. International Journal of Molecular Sciences. 2019 Mar 8;20(5):1195. doi: 10.3390/ijms20051195. PMID: 30857245

Resveratrol shifts energy metabolism to increase lipid oxidation in healthy old mice. Gimeno-Mallench L, Mas-Bargues C, Inglés M, Olaso G, Borras C, Gambini J, Vina J. Biomedicine & Pharmacotherapy. 2019 Oct;118:109130. doi: 10.1016/j.biopha.2019.109130. PMID: 31306969

Sarcopenia, frailty and their prevention by exercise. Nascimento CM, Ingles M, Salvador-Pascual A, Cominetti MR, Gomez-Cabrera MC, Viña J. Free Radical Biology & Medicine. 2019 Feb 20;132:42-49. doi: 10.1016/j.freeradbiomed.2018.08.035. PMID: 30176345

Sex Differences in Age-Associated Type 2 Diabetes in Rats-Role of Estrogens and Oxidative Stress. Díaz A, López-Grueso R, Gambini J, Monleón D, Mas-Bargues C, Abdelaziz KM, Viña J, Borrás C. Oxidative Medicine and Cellular Longevity. 2019 Apr 7;2019:6734836. doi: 10.1155/2019/6734836. PMID: 31089412

SOX2 expression diminishes with ageing in several tissues in mice and humans. Carrasco-Garcia E, Moreno-Cugnon L, Garcia I, Borras C, Revuelta M, Izeta A, Lopez-Lluch G, de Pancorbo MM, Vergara I, Vina J, Matheu A. Mechanisms of Ageing and Development. 2019 Jan;177:30-36. doi: 10.1016/j.mad.2018.03.008. PMID: 29574045

The Effectiveness of Vitamin E Treatment in Alzheimer’s Disease. Lloret A, Esteve D, Monllor P, Cervera-Ferri A, Lloret A. International Journal of Molecular Sciences. 2019 Feb 18;20(4):879. doi: 10.3390/ijms20040879. PMID:30781638

The free radical theory of frailty: Mechanisms and opportunities for interventions to promote successful aging. Viña J. Free radical biology & medicine. 2019 Apr;134:690-694. doi: 10.1016/j.freeradbiomed.2019.01.045. PMID: 30735838

Proyectos
Referencia: AC20/00026
Título: Asociación de chocolate fortificado con Vitamina E y ejercicio físco para reducir el riesgo de malnutrición proteica en personas mayores con deterioro cognitivo.
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: José Viña Rives
Duración: 2021 – 2023
Presupuesto: 169.098 €

Referencia: DIABFRAIL-LATAM-825546
Título: Scaling-up of and evidence-based intervention programme in older people with Diabetes and Frailty in LatinAmerica
Entidad Financiadora: European Commission
Investigador principal: José Viña Ribes
Duración: 2019 – 2024
Presupuesto: 273.720 €

Referencia: CB16/10/00435
Título: CIBER de Fragilidad y envejecimiento
Entidad Financiadora: Instituto de Salud Carlos III
Investigador principal: José Viña Ribes
Duración: 2017 –
Presupuesto:

Referencia: ADVANTAGE
Título: Managing Frailty. A comprehensive approach to promote a disability-free advanced age in Europe: the ADVANTAGE initiative
Entidad Financiadora: European Commission (3rd Health Program)
Investigador principal: Josep Redón i Mas, José Viña Ribes
Duración: 2016 – 2020
Presupuesto: 130.005 €

+ Información
Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. Ruiz J, Dent E, Morley J, Merchant R, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer J, Cesari M, Chen L, Cruz-Jentoft A, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster J, Rodriguez-Manas L, Rolland Y, Sanford A, Sinclair A, Viña Ribes J, Waters D, Won C, Woo J, Vellas B. Journal of Nutrition Health & Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3. PMID: 33155616

Título: Effect of two distinct implant macro-designs on the osseointegration of bicatortically installed implants in two topographic sites. A histomorphometric study in rabbit tibiae
Doctorando: Soto Peñaloza, David Reynaldo
Director: Peñarrocha Oltra, David; Viña Almunia, Jose; Martín De Llano, José Javier
Fecha: 15/11/2019
Universidad: Universitat de València

Título: Impacto del ejercicio físico a largo plazo en la neuroprotección de sujetos de mediana edad: estudio de los mecanismos moleculares involucrados
Doctorando: De La Rosa González, Adrián
Director: Gómez Cabrera, M. Carmen; Sanfeliú Pujol, Coral; Viña Ribes, José
Fecha: 05/06/2020
Universidad: Universitat de València

Título: Efecto de la ingesta de glutamato monosódico en la fisiopatología de la enfermedad de alzheimer
Doctorando: Yuste Pérez, Raquel
Director: Fuchsberger, Tanja; Viña Ribes, José; Lloret Alcañiz, Ana
Fecha: 22/07/2020
Universidad: Universitat de València

Título: Moderate overexpression of glucose-6-phosphate dehydrogenase improves healthspan in mice. Implications in skeletal muscle regeneration
Doctorando: Salvador Pascual, Andrea
Director: Viña Ribes, José; Gomez Cabrera, M. Carmen
Fecha: 15/07/2019
Universidad: Universitat de València

Título: Entrenamiento respiratorio: cambios en la presión inspiratoria máxima y relación con la funcionalidad del adulto mayor sano
Doctorando: Roldán Aliaga, Ainoa
Director: Blasco Lafarga, Cristina; Blasco Lafarga, Nieves M; Gómez Cabrera, M. Carmen
Fecha: 20/05/2019
Universidad: Universitat de València

Título: El sedentarismo en los adultos mayores del entorno rural: estrategias de entrenamiento concentrado versus distribuido
Doctorando: Monteagudo Chiner, Pablo
Director: Blasco Lafarga, Cristina; Gómez Cabrera, M. Carmen; Pesce, Caterina
Fecha: 26/07/2019
Universidad: Universitat de València

Título: Development of an ultrasound-based muscle texture analysis as a potential imaging biomarker for frailty phenotype
Doctorando: Mirón Mombiela, Rebeca
Director: Borrás Blasco, Consuelo; Forner Giner, Juana
Fecha: 28/01/2019
Universidad: Universitat de València

Título: Regulation of antioxidant defenses in the prevention of skeletal muscle deconditioning
Doctorando: Arc-Chagnaud, Coralie
Director: Viña Ribes, José; Gómez-Cabrera, Carmen; Chopard, Angèle; Brioche, Thomas
Fecha: 22/11/2019
Universidad: Universitat de València

Título: Influencia del procesamiento de la leche humana donada sobre la microbiota intestinal, la expresión genómica y el equilibrio oxidativo en recién nacidos pretérmino menores de 32 semanas de edad gestacional
Doctorando: Parra Llorca, Anna
Director: Vento, Máximo; Collado Amores, María Carmen; Serna García, Eva
Fecha: 23/02/2021
Universidad: Universitat de València

Título: Efecto de la activación del receptor PPARy/RxR como posible tratamiento de la enfermedad de Alzheimer. Papel de la genisteína
Doctorando: Muñoz Cebriá, José Enrique
Director: Viña, José; Borrás, Consuelo; Gambini, Juan
Fecha: 01/07/2020
Universidad: Universitat de València