Genistein effect on cognition in prodromal Alzheimer’s disease patients. The GENIAL clinical trial. Vina J, Escudero J, Baquero M, Cebrian M, Carbonell-Asins J, Munoz J, Satorres E, Melendez J, Ferrer-Rebolleda J, Cozar-Santiago M, Santabarbara-Gomez J, Jove M, Pamplona R, Tarazona-Santabalbina F, Borras C. Alzheimers Research & Therapy. 2022 Nov 4;14(1):164. doi: 10.1186/s13195-022-01097-2. PMID: 36329553

Genistein, a tool for geroscience. Bargues C, Borras C, Vina J. Mechanisms of Ageing and Development. 2022 Jun;204:111665. doi: 10.1016/j.mad.2022.111665. PMID: 35307412

Glucosamine supplementation improves physical performance in trained mice. De la Rosa A, Olaso-Gonzalez G, Garcia-Dominguez E, Mastaloudis A, Hester S, Wood S, Gomez-Cabrera M, Vina J. Medicine and Science in Sports and Exercise. 2022 Mar 1;54(3):466-474. doi: 10.1249/MSS.0000000000002821. PMID: 34711707

Glucose 6-P dehydrogenase-an antioxidant enzyme with regulatory functions in skeletal muscle during exercise. Garcia-Dominguez E, Carretero A, Vina-Almunia A, Domenech-Fernandez J, Olaso-Gonzalez G, Vina J, Gomez-Cabrera MC. Cells. 2022 Sep 28;11(19):3041. doi: 10.3390/cells11193041. PMID: 36231003

Impact of supplementation with vitamins B6, B12, and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: a systematic review. Olaso-Gonzalez G, Inzitari M, Bellelli G, Morandi A, Barcons N, Vina J. IUBMB Life. 2022 Jan;74(1):74-84. doi: 10.1002/iub.2507. PMID: 34058062

Long-lived humans have a unique plasma sphingolipidome. Pradas I, Jove M, Huynh K, Ingles M, Borras C, Mota-Martorell N, Galo-Licona JD, Puig J, Vina J, Meikle PJ, Pamplona R. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Apr 1;77(4):728-735. doi: 10.1093/gerona/glab360. PMID: 34871393

Multimodal strategy to rescue the brain in mild cognitive impairment: ketogenic oral nutrition supplementation with B vitamins and aerobic exercise. Cunnane SC, Swerdlow RH, Inzitari M, Olaso-Gonzalez G, Vina J. European Journal of Clinical Investigation. 2022 Sep;52(9):e13806. doi: 10.1111/eci.13806. PMID: 35488743

Real-life outcomes of a multicomponent exercise intervention in community-dwelling frail older adults and its association with nutritional-related factors. Millan-Domingo F, Tarazona-Santabalbina F, Carretero A, Olaso-Gonzalez G, Vina J, Gomez-Cabrera M. Nutrients. 2022 Dec 3;14(23):5147. doi: 10.3390/nu14235147. PMID: 36501177

Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice. Sanz-Ros J, Romero-Garcia N, Mas-Bargues C, Monleon D, Gordevicius J, Brooke RT, Dromant M, Diaz A, Derevyanko A, Guio-Carrion A, Roman-Dominguez A, Ingles M, Blasco MA, Horvath S, Vina J, Borras C. Science Advances. 2022 Oct 21;8(42):eabq2226. doi: 10.1126/sciadv.abq2226. PMID: 36260670

The multimodal action of genistein in Alzheimer’s and other age-related diseases. Mas-Bargues C, Borras C, Vina J. Free Radical Biology & Medicine. 2022 Apr;183:127-137. doi: 10.1016/j.freeradbiomed.2022.03.021. PMID: 35346775

The radiographic assessment of lung edema score of lung edema severity correlates with inflammatory parameters in patients with coronavirus disease 2019-Potential new admission biomarkers to predict coronavirus disease 2019 worsening. Marques P, Fernandez-Presa L, Carretero A, Gómez-Cabrera MC, Viña J, Signes-Costa J, Sanz MJ. Frontiers in Medicine. 2022 Aug 11;9:871714. doi: 10.3389/fmed.2022.871714. PMID: 36035415

Transcriptomic profile of epileptic children treated with ketogenic therapies. Ruiz-Herrero J, Olaso-Gonzalez G, Serna E, Canedo-Villarroya E, Correas A, Gambini J, Gomez-Cabrera M, Pedron-Giner C, Vina J. Journal of Integrative Neuroscience. 2022 Jan 28;21(1):31. doi: 10.31083/j.jin2101031. PMID: 35164467

Estrogen replacement therapy induces antioxidant and longevity-related genes in women after medically induced menopause. Borras C, Ferrando M, Ingles M, Gambini J, Lopez-Grueso R, Edo R, Mas-Bargues C, Pellicer A, Vina J. Oxidative Medicine and Cellular Longevity. 2021 Sep 9;2021:8101615. doi: 10.1155/2021/8101615. PMID: 34539974

Facial alveolar bone thickness and modifying factors of anterior maxillary teeth: a systematic review and meta-analysis of cone-beam computed tomography studies. Rojo-Sanchis J, Soto-Penaloza D, Penarrocha-Oltra D, Penarrocha-Diago M, Vina-Almunia J. BMC Oral Health. 2021 Mar 22;21(1):143. doi: 10.1186/s12903-021-01495-2. PMID: 33752651

Frailty assessment in a stable COPD cohort: is there a COPD-frail phenotype?. Naval E, Cruz Gonzalez M, Giraldos S, Calatayud J, Jornet M, Lluch I, Meseguer M, Ruiz Cubillan JJ, Vina J, Tarazona-Santabalbina FJ. COPD-Journal of Chronic Obstructive Pulmonary Disease. 2021 Oct;18(5):525-532. doi: 10.1080/15412555.2021.1975670. PMID: 34503389

Glucose 6-P dehydrogenase delays the onset of frailty by protecting against muscle damage. Arc-Chagnaud C, Salvador-Pascual A, Garcia-Dominguez E, Olaso-Gonzalez G, Correas A, Serna E, Brioche T, Chopard A, Fernandez-Marcos P, Serrano M, Serrano A, Munoz-Canoves P, Sebastia V, Vina J, Carmen Gomez-Cabrera M. Journal of Cachexia Sarcopenia and Muscle. 2021 Dec;12(6):1879-1896. doi: 10.1002/jcsm.12792. PMID: 34704386

Healthcare for older adults, where are we moving towards?. Tarazona-Santabalbina F, Gonzalez S, Navarro J, Vina J. International Journal of Environmental Research and Public Health. 2021 Jun 8;18(12):6219. doi: 10.3390/ijerph18126219. PMID: 34201289

Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers. Garcia-Gimenez J, Mena-Molla S, Tarazona-Santabalbina F, Vina J, Gomez-Cabrera M, Pallardo F. International Journal of Environmental Research and Public Health. 2021 Feb 15;18(4):1883. doi: 10.3390/ijerph18041883. PMID: 33672064

Integrating pheromonal and spatial information in the amygdalo-hippocampal network. Villafranca-Faus M, Esteban Vila-Martin M, Esteve D, Merino E, Teruel-Sanchis A, Cervera-Ferri A, Martinez-Ricos J, Lloret A, Lanuza E, Teruel-Marti V. Nature Communications. 2021 Sep 6;12(1):5286. doi: 10.1038/s41467-021-25442-5. PMID: 34489431

Is oxidative stress the link between cerebral small vessel disease, sleep disruption, and oligodendrocyte dysfunction in the onset of Alzheimer’s disease?. Lloret A, Esteve D, Lloret MA, Monllor P, Lopez B, Leon JL, Cervera-Ferri A. Frontiers in Physiology. 2021 Aug 25;12:708061. doi: 10.3389/fphys.2021.708061. PMID: 34512381

Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus. Borras C, Abdelaziz KM, Diaz A, Gambini J, Jove M, Lopez-Grueso R, Mas-Bargues C, Monleon D, Pamplona R, Vina J. Mechanisms of Ageing and Development. 2021 Dec;200:111596. doi: 10.1016/j.mad.2021.111596. PMID: 34774606

Lipid peroxidation as measured by chromatographic determination of malondialdehyde. Human plasma reference values in health and disease. Mas-Bargues C, Escrivá C, Dromant M, Borrás C, Viña J. Archives of Biochemistry and Biophysics. 2021 Sep 30;709:108941. doi: 10.1016/j.abb.2021.108941. PMID: 34097903

Moderate Red Wine Consumption Increases the Expression of Longevity-Associated Genes in Controlled Human Populations and Extends Lifespan in Drosophila melanogaster. Gambini J, Gimeno-Mallench L, Olaso-Gonzalez G, Mastaloudis A, Traber M, Monleon D, Borras C, Vina J. Antioxidants. 2021 Feb 16;10(2):301. doi: 10.3390/antiox10020301. PMID: 33669360

Multicomponent training prevents memory deficit related to amyloid-beta protein-induced neurotoxicity. Soares CB, Dare LR, Lima KR, Lopes LF, Santos A, Garcia Dos A, Schimidt HL, Carpes FP, Lloret A, Vina J, Mello-Carpes P. Journal of Alzheimer’s Disease. 2021;83(1):143-154. doi: 10.3233/JAD-210424. PMID: 34275902

Overexpression of glucose 6 phosphate dehydrogenase preserves mouse pancreatic beta cells function until late in life. De la Rosa A, Gomez-Cabrera M, Vinue A, Gonzalez-Navarro H, Sanchez-Andres J, Vina J. Free radical biology & medicine. 2021 Feb 20;164:149-153. doi: 10.1016/j.freeradbiomed.2020.12.439. PMID: 33418115

Redox-related biomarkers in physical exercise. Gomez-Cabrera C, Carretero A, Millan-Domingo F, Garcia-Dominguez E, Correas AG, Olaso-Gonzalez G, Vina J. Redox Biology. 2021 Jun;42:101956. doi: 10.1016/j.redox.2021.101956. PMID: 33811000

Serum Levels of Clusterin, PKR, and RAGE Correlate with Amyloid Burden in Alzheimer’s Disease. Monllor P, Giraldo E, Badia M, de la Asuncion J, Alonso M, Lloret A, Vina J. Journal of Alzheimer’s disease. 2021;80(3):1067-1077. doi: 10.3233/JAD-201443. PMID: 33646167

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates. Duro-Castano A, Borras C, Herranz-Perez V, Blanco-Gandia M, Conejos-Sanchez I, Arminan A, Mas-Bargues C, Ingles M, Minarro J, Rodriguez-Arias M, Garcia-Verdugo J, Vina J, Vicent M. Science Advances. 2021 Mar 26;7(13):eabf9180. doi: 10.1126/sciadv.abf9180. PMID: 33771874

The oscillatory profile induced by the anxiogenic drug FG-7142 in the amygdala-hippocampal network is reversed by infralimbic deep brain stimulation: relevance for mood disorders. Vila-Merkle H, Gonzalez-Martinez A, Campos-Jimenez R, Martinez-Ricos J, Teruel-Marti V, Blasco-Serra A, Lloret A, Celada P, Cervera-Ferri A. Biomedicines. 2021 Jul 6;9(7):783. doi: 10.3390/biomedicines9070783. PMID: 34356846

Extracellular vesicles and redox modulation in aging. Borras Blasco C, Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. Free Radical Biology and Medicine. 2020 Mar;149:44-50. doi: 10.1016/j.freeradbiomed.2019.11.032. PMID: 31783096

Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation. Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Viña Ribes J, Borras Blasco C. Biomolecules. 2020 Jun 25;10(6):957. doi: 10.3390/biom10060957. PMID: 32630449

Garcinoic acid prevents beta-amyloid (Abeta) deposition in the mouse brain. Marinelli R, Torquato P, Bartolini D, Mas Bargues C, Bellezza G, Gioiello A, Borras Blasco C, De Luca A, Fallarino F, Sebastiani B, Mani S, Sidoni A, Viña Ribes J, Leri M, Bucciantini M, Nardiello P, Casamenti F, Galli F. Journal of biological chemistry. 2020 Aug 14;295(33):11866-11876. doi: 10.1074/jbc.RA120.013303. PMID: 32616652

Hippocampal oscillatory dynamics and sleep atonia are altered in an animal model of fibromyalgia: implications in the search for biomarkers. Blasco-Serra A, Alfosea-Cuadrado G, Cervera-Ferri A, Gonzalez-Soler E, Lloret Alcañiz A, Martinez-Ricos J, Teruel-Marti V, Valverde-Navarro A. Journal of Comparative Neurology. 2020 Jun;528(8):1367-1391. doi: 10.1002/cne.24829. PMID: 31785155

Increased basal antioxidant levels in RCAN1 – deficient mice lowers oxidative injury after acute paraquat insult. Lloret Alcañiz A, Monllor Taltavull P, Fuchsberger T, Giraldo Reboloso E, Perluigi M, Viña Ribes J. Free Radical Research. 2020 Jun;54(6):442-454. doi: 10.1080/10715762.2020.1798002. PMID:32686528

Influence of occlusal loading on peri-implant inflammatory cytokines in crevicular fluid: a prospective longitudinal study. Viña Almunia J, Pellicer-Chover H, Garcia-Mira B, Romero-Millan J, Penarrocha-Oltra D, Penarrocha-Diago M. International Journal Of Implant Dentistry. 2020 Oct 28;6(1):71. doi: 10.1186/s40729-020-00262-2. PMID: 33111201

Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: an experimental study in rabbits. Favero G, Vina-Almunia J, Carda C, de Llano J, Garcia-Mira B, Soto-Penaloza D, Penarrocha-Diago M, Botticelli D. International Journal of Implant Dentistry. 2020 Mar 4;6(1):9. doi: 10.1186/s40729-020-0206-2. PMID: 32128632

Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker. Lloret M, Cervera-Ferri A, Nepomuceno M, Monllor P, Esteve D, Lloret Alcañiz A. International Journal of Molecular Sciences. 2020 Feb 10;21(3):1168. doi: 10.3390/ijms21031168. PMID: 32050587

Methionine transsulfuration pathway is upregulated in long-lived humans. Mota-Martorell N, Mariona J, Consuelo B, Rebeca B, Elia O, Joaquim S, Rosanna C, Irene P, Galo-Licona J, Josep P, Jose V, Reinald P. Free Radical Biology & Medicine. 2020 Nov 30;162:38-52. doi: 10.1016/j.freeradbiomed.2020.11.026. PMID: 33271279

Modulating Oxidant Levels to Promote Healthy Aging. Viña Ribes J, Olaso González G, Arc-Chagnaud C, De La Rosa González A, Gomez Cabrera M. Antioxidants & Redox Signaling. 2020 Sep 10;33(8):570-579. doi: 10.1089/ars.2020.8036. PMID: 32008355

Multicomponent Exercise Training Combined with Nutritional Counselling Improves Physical Function, Biochemical and Anthropometric Profiles in Obese Children: A Pilot Study. Cordellat Marzal A, Padilla Lopez B, Grattarola P, Garcia Lucerga C, Crehuá Gaudiza E, Nuñez Gomez F, Martinez Costa C, Blasco Lafarga M. Nutrients. 2020 Sep 6;12(9):2723. doi: 10.3390/nu12092723. PMID: 32899955

Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits. Serna-Garcia M, Peiro R, Serna E, Santacreu MA. Animals. 2020 Oct 20;10(10):1924. doi: 10.3390/ani10101924. PMID: 33092110

Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies. Cenini G, Lloret Alcañiz A, Cascella R. Oxidative Medicine and Cellular Longevity. 2020 May 4;2020:1270256. doi: 10.1155/2020/1270256. PMID: 32454930

Physical exercise in the prevention and treatment of Alzheimer’s disease. De La Rosa González A, Olaso Gonzalez G, Arc-Chagnaud C, Millán F, Salvador Pascual A, Garcia Lucerga C, Blasco Lafarga M, Garcia Dominguez E, Carretero Martínez A, Correas A, Viña Ribes J, Gomez Cabrera M. Journal of Sport and Health Science. 2020 Sep;9(5):394-404. doi: 10.1016/j.jshs.2020.01.004. PMID: 32780691

Redox modulation of muscle mass and function. Gomez Cabrera M, Arc-Chagnaud C, Salvador Pascual A, Brioche T, Chopard A, Olaso González G, Viña Ribes J. Redox Biology. 2020 Aug;35:101531. doi: 10.1016/j.redox.2020.101531. PMID: 32371010

Relationship between Diet, Microbiota, and Healthy Aging. Sanchez-Morate E, Gimeno Mallench L, Stromsnes K, Sanz Ros J, Roman-Dominguez A, Parejo-Pedrajas S, Inglés De La Torre M, Olaso González G, Gambini Buchon J, Mas Bargues C. Biomedicines. 2020 Aug 14;8(8):287. doi: 10.3390/biomedicines8080287. PMID: 32823858

Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. Ruiz J, Dent E, Morley J, Merchant R, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer J, Cesari M, Chen L, Cruz-Jentoft A, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster J, Rodriguez-Manas L, Rolland Y, Sanford A, Sinclair A, Viña Ribes J, Waters D, Won C, Woo J, Vellas B. Journal of Nutrition Health & Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3. PMID: 33155616

Special issue: Exercise redox biology from health to performance. Gomez Cabrera M, Viña Ribes J, Olaso González G. Redox Biology. 2020 Aug;35:101584. doi: 10.1016/j.redox.2020.101584. PMID:32448750

Special issue: Redox Signalling in Health and Disease. Borras Blasco C, Viña Ribes J. Free Radical Biology And Medicine. 2020 Mar;149:1. doi: 10.1016/j.freeradbiomed.2020.02.009. PMID: 32061736

The Status of EGFR Modulates the Effect of miRNA-200c on ZEB1 Expression and Cell Migration in Glioblastoma Cells. Munoz-Hidalgo L, San-Miguel T, Megias J, Serna E, Calabuig-Farinas S, Monleon D, Gil-Benso R, Cerda-Nicolas M, Lopez-Gines C. International Journal of Molecular Sciences. 2020 Dec 31;22(1):368. doi: 10.3390/ijms22010368. PMID: 33396457

Transcriptomic identification of miR-205 target genes potentially involved in metastasis and survival of cutaneous malignant melanoma. Sanchez Sendra B, Serna García E, Navarro Cerveró L, González Muñoz J, Portero Trigo J, Ramos Jarero A, Murgui Faubel A, Monteagudo Castro C. Scientific Reports. 2020 Mar 16;10(1):4771. doi: 10.1038/s41598-020-61637-4. PMID: 32179834