Technological Offer

Since its formal establishment as a Biomedical Research Institute in 2010, INCLIVA has achieved significant milestones arising from its research activities. These include more than 20 patents, 4 registered software programs, and 4 spin-off companies created as a result of research conducted at INCLIVA.

OPTIMIZATION DEVICE FOR INTRAURETHRAL LUBRICATION IN PEDIATRIC PATIENTS

Group: Urología

Type: Modelo de utilidad

Novel treatment with PPAR modulators for metabolic diseases

Group: Química Médica

Type: Patente

Cathlab Sim: SOFTWARE FOR THE SIMULATION OF PERCUTANEOUS CARDIAC INTERVENTIONS AND THE TRAINING OF HEALTHCARE STAFF

Group: Cardiología Clínica

Type: Software

Haloperidol para el tratamiento de la atrofia muscular espinal

Group: Genómica Traslacional Humana

Type: Patente

AMMON-OHE: A Machine Learning Model to Predict Occurrence of Overt Hepatic Encephalopathy in Patients with Cirrhosis

Group: Research Group on Neurological Impairment

Type: Patent

Device for blood cannulation for haemodialysis

Group:

Type: Patent

SepAsT: Software for early sepsis diagnosis of sepsis and patients clinical clourse and septic shock

Group: Research Group on Epigenomics and Translational Epigenetics

Type: Software

Musashi 2 (MSI2) como diana terapéutica para el tratamiento de la distrofia miotónica tipo 1 y 2

Group: Research Group on Human Translational Genomics

Type: Patent

Method for minimal residual disease detection in cancer patients

Group: : Research Group of Innovative Diagnostic and Therapeutical Developments in Solid Tumors

Type: Patent

Nanoparticles-based therapy for ischemic cardiopathies

Group: Grupo de Investigación Traslacional en Cardiopatía Isquémica

Type: Patent

Microbiological Information Bulletin(BIMIC)

Group: Grupo de Investigación en Microbiología Molecular y Patogénesis Microbiana

Type: Software

EndosCitas y EndosNet

Group: Servicio de Medicina Digestiva / Unidad de endoscopias

Type: Software

Angiopath

Group: Grupo de Investigación Translacional de Tumores Sólidos Pediátricos

Type: Software

HISTSHOCK IVD: A diagnostic and Decision-Support Software for Sepsis and Septic Shock Management

Group: Epigenómica y Epigenética traslacional

Type: Software

Algorithmic methodology for opportunistic detection and monitoring of chronic kidney disease

Group: Renal Disease Group

Type: Know-how

LIPACS-PAT: Prescription support tool for lipid-lowering therapy after acute coronary syndrome

Group:

Type: Software

Left ventricular thrombus risk calculation tool after myocardial infarction

Group:

Type: Software

Subcutaneous port for administration of heparins

Group: Grupo Clínico Asociado de Investigación en Cuidados de la Salud. INVESTENF-INCLIVA

Type: Device

 

Technology-based Spin-Off companies:

Seqplexing was founded in 2013 with the aim of developing solutions for research and clinical applications based on advanced genetic techniques and platforms, particularly next-generation sequencing (NGS). The company addresses the need for reliable protocols for amplicon and gene sequencing by developing ready-to-use solutions that can be easily implemented in laboratories.

Seqplexing’s mission is to support laboratories that, due to the demands of their day-to-day activities, lack the time or resources to develop optimised protocols for sequencing genes or regions of interest. The company transforms the components required for these techniques into commercial kits, providing a comprehensive service covering the entire workflow, from sample preparation to the final analysis of results.

Epidisease was founded in 2014 as a result of a project led by researchers from INCLIVA and the Biomedical Research Networking Centre (CIBER) in the field of Rare Diseases, with the aim of translating expertise in epigenetics and biomedical sciences into solutions that benefit society.

Epigenetics studies the factors and mechanisms involved in regulating gene expression. The importance of this field continues to grow, as findings arising from initiatives such as the Human Genome Project have shown that the molecular basis of cellular function, development, ageing and many diseases extends far beyond the DNA sequence itself. More recent findings from the Roadmap Epigenomics Project have further advanced our understanding of these mechanisms.

Epidisease’s mission is to leverage its extensive expertise in epigenetics to provide its clients with biomedical solutions, diagnostic tools and new therapies, while promoting translational research aimed at improving human health and well-being.

Nela BioDynamics is a biomedical technology development company that emerged from collaboration within the Valencian university ecosystem. Its multidisciplinary team brings together researchers with expertise in biomedicine and engineering.

The company originated from the results of a Master’s Thesis in Biomedical Engineering, which led to two patents covering a novel intramedullary fixation system for joint endoprostheses, fracture nails and exoprostheses, as well as a percutaneous collar for ostomies.

NELA’s intramedullary implant technology enables a personalised fit for each patient and avoids conventional fixation techniques based on impact press-fitting or the use of bone cement. This can result in shorter surgical procedures, reduced pain, improved success rates and a better quality of life for patients.

NELA’s mission is to address unmet medical needs while generating a positive socioeconomic impact.

ARTHEx BIOTECH is a spin-off company from the Universitat de València developing advanced RNA-based therapies for genetic diseases. Its team has extensive expertise in drug discovery and in the role of microRNAs in neuromuscular diseases. The company is also supported by internationally renowned scientific and clinical advisors who contribute their expertise to the successful development of its therapeutic programmes.

ARTHEx Biotech’s mission is to develop effective treatments for unmet medical needs. Its initial focus is on investigating anti-microRNA therapies for the treatment of myotonic dystrophy type 1 (DM1), a rare disease affecting more than 900,000 people worldwide, with an estimated prevalence of 1 in 8,000.