Grupo Clínico Asociado en Medicina Digestiva

Grupo Clínico Asociado

Diagnóstico y tratamiento de la encefalopatía hepática mínima, hepatocarcinoma, hipertensión portal y NASH

Diagnóstico y tratamiento de la patología funcional digestiva

Diagnóstico y tratamiento de patología pancreática

Establecer un equipo de investigación traslacional en patología inflamatoria intestinal, pancreática y hepática

Coordinador
Dra. Isabel Pascual Moreno
isabel.pascual-moreno@uv.es

INVESTIGADORES
R4 Senior

Isabel Pascual Moreno    

R3 Consolidado

Paloma Lluch García
Andrés Peña Aldea
Joan Tosca Cuquerella
Marta Maia Boscá Watts
Vicente Sanchiz Soler

R2 Novel / Emergente

Marta Ponce Romero
Pilar Más Mercader

R1 Predoctoral

Eva Romero González
María Capilla Lozano
Carles Suria Bolufer

STAFF
Colaborador/a

Pablo Navarro Cortés
Ana Sanahuja Martínez
Rosana Villagrasa Manzano
Rosario Antón Ausejo
Sherly Hernández
Consuelo Gálvez Castillo

Enfermero/a

Amparo Ruiz Alvárez
Nuria Casasús Moya

Técnico/a

Lorena Boronat Cifre
Desamparados Giménez Choví

Apoyo
Publicaciones
Endoscopic treatment (endoscopic balloon dilation/self-expandable metal stent) vs surgical resection for the treatment of de novo stenosis in Crohn’s disease (ENDOCIR study): an open-label, multicentre, randomized trial. Loras C, Ruiz-Ramirez P, Romero J, Andújar X, Bargallo J, Bernardos E, Boscá-Watts MM, Brugiotti C, Brunet E, Busquets D, Cerrillo E, Cortina FJ, Díaz-Milanés JA, Dueñas C, Farrés R, Golda T, González-Huix F, Gornals JB, Guardiola J, Julià D, Lira A, Llaó J, Mañosa M, Marin I, Millán M, Monfort D, Moro D, Mullerat J, Navarro M, Pérez Roldán F, Pijoan E, Pons V, Reyes J, Rufas M, Sainz E, Sanchiz V, Serracant A, Sese E, Soto C, Troya J, Zaragoza N, Tebé C, Paraira M, Sudrià-Lopez E, Mayor V, Fernández-Bañares F, Esteve M. Trials. 2023 Jun 27;24(1):432. doi: 10.1186/s13063-023-07447-1. PMID: 37365665

Evaluation of results after 112 radioembolizations with 90Y-microspheres. Casans-Tormo I, Guijarro-Rosaleny J, Lluch-Garcia P, Rodriguez-Parra H, Rosello-Keranen S, Asensio-Valero L. Revista Espanola de Medicina Nuclear e Imagen Molecular. 2023 Jul-Aug;42(4):255-264. doi: 10.1016/j.remnie.2023.05.004. PMID: 37269983

I-CARE, a European prospective cohort study assessing safety and effectiveness of biologics in inflammatory bowel disease. Peyrin-Biroulet L, Rahier J, Kirchgesner J, Abitbol V, Shaji S, Armuzzi A, Karmiris K, Gisbert J, Bossuyt P, Helwig U, Burisch J, Yanai H, Doherty G, Magro F, Molnar T, Lowenberg M, Halfvarson J, Zagorowicz E, Rousseau H, Baumann C, Baert F, Beaugerie L, Puchades Lanza L, I-CARE Collaborator Group. Clinical Gastroenterology and Hepatology. 2023 Mar;21(3):771-788.e10. doi: 10.1016/j.cgh.2022.09.018. PMID: 36152897

Liver disorders and celiac disease. Monton Rodriguez C, Sanchez Serrano J, Poyatos Garcia P, Abril Garcia C, Gomez Medina C, Capilla-Lozano M, Lluch Garcia P, Pascual Moreno I. Revista Espanola de Enfermedades Digestivas. 2023 May 19. doi: 10.17235/reed.2023.9516/2023. PMID: 37204091

Long-term outcomes of biological therapy in Crohn’s disease complicated with internal fistulizing disease: BIOSCOPE study from GETECCU. Acosta M, Fernandez-Clotet A, Mesonero F, Garcia-Alonso F, Casanova M, Fernandez-de la Varga M, Canete F, de Castro L, Gutierrez A, Sicilia B, Cano V, Merino O, de Francisco R, Gonzalez-Partida I, Suris G, Torrealba L, Ferreiro-Iglesias R, Castro B, Marquez L, Sobrino A, Elorza A, Calvet X, Varela P, Vicente R, Bujanda L, Lario L, Mancenido N, Garcia-Sepulcre M, Iglesias E, Rodriguez C, Piqueras M, Ferrer Rosique J, Lucendo A, Benitez O, Garcia M, Olivares D, Gonzalez-Munoza C, Lopez-Cauce B, Morales Alvarado V, Spicakova K, Brotons A, Bermejo F, Almela P, Ispizua N, Gilabert P, Tardillo C, Munoz F, Navarro P, Madrigal Dominguez R, Sendra P, Hinojosa E, Sainz E, Martin-Arranz M, Carpio D, Ricart E, Caballol B, Nunez L, Barrio J, Gisbert J, Iborra M, Calafat M, Hernandez V, Perez R, Cabriada J, Domenech E, Rodriguez-Lago I. American Journal of Gastroenterology. 2023 Jun 1;118(6):1036-1046. doi: 10.14309/ajg.0000000000002152. PMID: 36516073

Real-World evidence of tofacinitib in ulcerative colitis: short-term and long-term effectiveness and safety. Chaparro M, Acosta D, Rodríguez C, Mesonero F, Vicuña M, Barreiro-de Acosta M, Fernández-Clotet A, Hernández Martínez Á, Arroyo M, Vera I, Ruiz-Cerulla A, Sicilia B, Cabello Tapia MJ, Muñoz Villafranca C, Castro-Poceiro J, Martínez Cadilla J, Sierra-Ausín M, Vázquez Morón JM, Vicente Lidón R, Bermejo F, Royo V, Calafat M, González-Muñoza C, Leo Carnerero E, Manceñido Marcos N, Torrealba L, Alonso-Galán H, Benítez JM, Ber Nieto Y, Diz-Lois Palomares MT, García MJ, Muñoz JF, Armesto González EM, Calvet X, Hernández-Camba A, Madrigal Domínguez RE, Menchén L, Pérez Calle JL, Piqueras M, Dueñas Sadornil C, Botella B, Martínez-Pérez TJ, Ramos L, Rodríguez-Grau MC, San Miguel E, Fernández Forcelledo JL, Fradejas Salazar PM, García-Sepulcre M, Gutiérrez A, Llaó J, Sesé Abizanda E, Boscá-Watts M, Iyo E, Keco-Huerga A, Martínez Bonil C, Peña González E, Pérez-Galindo P, Varela P, Gisbert JP. The American Journal of Gastroenterology. 2023 Jul 1;118(7):1237-1247. doi: 10.14309/ajg.0000000000002145. PMID: 36716287

Ustekinumab and vedolizumab for the prevention of postoperative recurrence of Crohn’s disease: results from the ENEIDA registry. Manosa M, Fernandez-Clotet A, Nos P, Martin-Arranz M, Mancenido N, Carbajo A, Hinojosa E, Hernandez-Camba A, Munoz-Perez R, Bosca-Watts M, Calvo M, Sierra-Ausin M, Sanchez-Rodriguez E, Barreiro-de Acosta M, Nunez-Alonso A, Zabana Y, Marquez L, Gisbert J, Guardiola J, Sainz E, Delgado-Guillena P, Busquets D, van Domselaar M, Girona E, Lorente R, Casas-Deza D, Huguet J, Maestro S, Cabello M, Castro J, Iborra M, Canete F, Calafat M, Domenech E. Digestive and Liver Disease. 2023 Jan;55(1):46-52. doi: 10.1016/j.dld.2022.07.013. PMID: 35948459

Adherence to endoscopic surveillance for advanced lesions and colorectal cancer in inflammatory bowel disease: an AEG and GETECCU collaborative cohort study. Pilar Ballester M, Mesonero F, Florez-Diez P, Gomez C, Fuentes-Valenzuela E, Martin N, Senosiain C, Vela M, Fernandez-Clotet A, Perez P, Rubin de Celix C, Calvino-Suarez C, Hermida B, Munoz R, Gonzalez-Vivo M, Brunet E, Jimenez N, Botella B, Yebra J, Suarez-Ferrer C, Bouhmidi A, Lopez-Serrano A, Ponferrada A, Duenas C, Minguez M. Alimentary Pharmacology & Therapeutics. 2022 Jun;55(11):1402-1413. doi: 10.1111/apt.16832. PMID: 35224758

Aggressive or moderate fluid resuscitation in acute pancreatitis. De-Madaria E, Buxbaum JL, Maisonneuve P, Garcia Garcia de Paredes A, Zapater P, Guilabert L, Vaillo-Rocamora A, Rodriguez-Gandia MA, Donate-Ortega J, Lozada-Hernandez EE, Collazo Moreno AJR, Lira-Aguilar A, Llovet LP, Mehta R, Tandel R, Navarro P, Sanchez-Pardo AM, Sanchez-Marin C, Cobreros M, Fernandez-Cabrera I, Casals-Seoane F, Deza D, Lauret-Brana E, Marti-Marques E, Camacho-Montano LM, Ubieto V, Ganuza M, Bolado F. New England Journal of Medicine. 2022 Sep 15;387(11):989-1000. doi: 10.1056/NEJMoa2202884. PMID: 36103415

Association of golimumab trough concentrations during maintenance with clinical, biological, endoscopic and histologic remission in patients with ulcerative colitis. Taxonera C, Fernandez-Acenero MJ, Olivares D, Calvo M, Casis B, Bermejo F, Lopez Serrano P, Iborra M, Mesonero F, Watts Bosca M, Diaz del Arco C, Vera I, Olivares S, Algaba A, Alba C. Alimentary Pharmacology & Therapeutics. 2022 Aug;56(4):614-624. doi: 10.1111/apt.16964. PMID: 35509152

Authors reply to comments high recurrence rate after non-surgical treatment of chronic anal fissure: can it be prevented?. Espi A, Herreros B, Minguez M. Diseases of the Colon and Rectum. 2022 May 1;65(5):e340. doi: 10.1097/DCR.0000000000002435. PMID: 35185136

Autoimmune hepatitis triggered by COVID-19. Monton Rodriguez C, Navarro Cortes P, Lluch Garcia P, Minguez Perez M. Revista Espanola de Enfermedades Digestivas. 2022 Jan;114(1):64-65. doi: 10.17235/reed.2021.8045/2021. PMID: 34015933

Biological treatment interruption in Inflammatory Bowel Disease: motivation and predictive factors. González MRD, Ballester MP, Romero-González E, Sánchez-Pardo AM, Marti-Aguado D, Tosca J, Suria C, Ausejo RA, Moreno IP, Silvestre MDP, Pérez MM, Bosca-Watts MM. Gastroenterologia y Hepatologia. 2022 Nov 11;S0210-5705(22)00267-9. doi: 10.1016/j.gastrohep.2022.10.021. PMID: 36375696

Caustic ingestion: a risk-based algorithm. Tosca J, Sanchez A, Sanahuja A, Villagrasa R, Poyatos P, Mas P, Pascual I, Lluch P, Herreros B, Pena A, Sanchiz V, Minguez M. American Journal of Gastroenterology. 2022 Oct 1;117(10):1593-1604. doi: 10.14309/ajg.0000000000001953. PMID: 36194047

Correction to: Multicenter study of lumen-apposing metal stents with or without pigtail in endoscopic ultrasound-guided biliary drainage for malignant obstruction-BAMPI TRIAL: an open-label, randomized controlled trial protocol. Garcia-Sumalla A, Loras C, Sanchiz V, Sanz R, Vazquez-Sequeiros E, Aparicio J, de la Serna-higuera C, Luna-Rodriguez D, Andujar X, Capilla M, Barbera T, Foruny-Olcina J, Martinez B, Dura M, Salord S, Laquente B, Tebe C, Videla S, Perez-Miranda M, Gornals J, Spanish Working Grp Endoscopic. Trials. 2022 Mar 14;23(1):214. doi: 10.1186/s13063-022-06138-7. PMID: 35287708

Correction: Chaparro et al. Incidence, clinical characteristics and management of inflammatory bowel disease in Spain: large-scale epidemiological study. J. Clin. Med. 2021, 10, 2885. Chaparro et al.; on behalf of the EpidemIBD Study Group of Geteccu. Journal of Clinical Medicine. 2022 Sep 30;11(19):5816. doi: 10.3390/jcm11195816. PMID: 36233844

Factors associated with lesion detection in colonoscopy among different indications. Mangas-Sanjuan C, Seoane A, Alvarez-Gonzalez M, Lue A, Suarez A, Alvarez-Garcia V, Bujanda L, Portillo I, Gonzalez N, Cid-Gomez L, Cubiella J, Rodriguez-Camacho E, Ponce M, Diez-Redondo P, Herraiz M, Pellise M, Ono A, Baile-Maxia S, Medina-Prado L, Murcia O, Zapater P, Jover R. United European Gastroenterology Journal. 2022 Nov;10(9):1008-1019. doi: 10.1002/ueg2.12325. PMID: 36300971

Ferric carboxymaltose improves the quality of life of patients with inflammatory bowel disease and iron deficiency without anaemia. Huguet J, Cortes X, Bosca-Watts M, Munoz M, Maroto N, Iborra M, Hinojosa E, Capilla M, Asencio C, Amoros C, Paredes J. Journal of Clinical Medicine. 2022 May 15;11(10):2786. doi: 10.3390/jcm11102786. PMID: 35628914

Immigrant IBD patients in Spain are younger, have more extraintestinal manifestations and use more biologics than native patients. Gutierrez A, Zapater P, Ricart E, et al. Frontiers in Medicine. 2022 Feb 1;9:823900. doi: 10.3389/fmed.2022.823900. PMID: 35178413

Impact of the COVID-19 pandemic on a cancer fast-track programme. Martinez M, Moragon S, Ortega-Morillo B, Monton-Bueno J, Simon S, Rosello S, Insa A, Viala A, Navarro J, Sanmartin A, Fluixa C, Julve A, Soriano D, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner M, Cano A, Silvestre A, Teruel A, Bermejo B, Cervantes A, Chirivella Gonzalez I. Cancer Control. 2022 Jan-Dec;29:10732748221131000. doi: 10.1177/10732748221131000. PMID: 36355430

Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease. Carrascal M, Areny-Balaguero A, de-Madaria E, Cardenas-Jaen K, Garcia-Rayado G, Rivera R, Martin Mateos R, Pascual-Moreno I, Gironella M, Abian J, Closa D. The Journal of pathology. 2022 Jan;256(1):83-92. doi: 10.1002/path.5811. PMID: 34599510

Integrative immune transcriptomic classification improves patient selection for precision immunotherapy in advanced gastro-oesophageal adenocarcinoma. Cabeza-Segura M, Gambardella V, Gimeno-Valiente F, Carbonell-Asins JA, Alarcon-Molero L, Gonzalez-Vilanova A, Zuniga-Trejos S, Rentero-Garrido P, Villagrasa R, Gil M, Dura A, Richart P, Alonso N, Huerta M, Rosello S, Roda D, Tarazona N, Martinez-Ciarpaglini C, Castillo J, Cervantes A, Fleitas T. British Journal of Cancer. 2022 Dec;127(12):2198-2206. doi: 10.1038/s41416-022-02005-z. PMID: 36253523

Long-term real-world effectiveness and safety of ustekinumab in Crohn’s disease patients: the SUSTAIN Study. Chaparro M, Baston-Rey I, Fernandez-Salgado E, Gonzalez Garcia J, Ramos L, Diz-Lois Palomares M, Arguelles-Arias F, Iglesias Flores E, Cabello M, Rubio Iturria S, Nunez Ortiz A, Charro M, Ginard D, Duenas Sadornil C, Merino Ochoa O, Busquets D, Iyo E, Gutierrez Casbas A, Ramirez de la Piscina P, Bosca-Watts M, Arroyo M, Garcia M, Hinojosa E, Gordillo J, Martinez Montiel P, Velayos Jimenez B, Quilez Ivorra C, Vazquez Moron J, Maria Huguet J, Gonzalez-Lama Y, Munagorri Santos A, Amo V, Martin-Arranz M, Bermejo F, Martinez Cadilla J, Rubin de Celix C, Fradejas Salazar P, San Roman A, Jimenez N, Garcia Lopez S, Figuerola A, Jimenez I, Martinez Cerezo F, Taxonera C, Varela P, de Francisco R, Monfort D, Molina Arriero G, Hernandez Camba A, Garcia-Alonso F, Van Domselaar M, Pajares Villarroya R, Nunez A, Rodriguez Moranta F, Marin-Jimenez I, Robles Alonso V, Martin Rodriguez M, Camo-Monterde P, Garcia Tercero I, Navarro Llavat M, Arias Garcia L, Hervias Cruz D, Sulleiro S, Novella C, Vispo E, Barreiro-de Acosta M, Gisbert J. Inflammatory Bowel Diseases. 2022 Nov 2;28(11):1725-1736. doi: 10.1093/ibd/izab357. PMID: 35166347

Management of patients with Intestinal Bowel Disease and COVID-19: a review of current evidence and future perspectives. Suria C, Bosca-Watts MM, Navarro P, Tosca J, Anton R, Sanahuja A, Revaliente M, Minguez M. Gastroenterologia y Hepatología. 2022 May;45(5):383-389. doi: 10.1016/j.gastrohep.2021.06.005. PMID: 34171421

Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy. Ballester M, Gallego J, Fiorillo A, Casanova-Ferrer F, Gimenez-Garzo C, Escudero-Garcia D, Tosca J, Rios M, Monton C, Durban L, Ballester J, Benlloch S, Urios A, San-Miguel T, Kosenko E, Serra M, Felipo V, Montoliu C. Scientific Reports. 2022 Feb 14;12(1):2463. doi: 10.1038/s41598-022-06416-z. PMID: 35165326

Multicenter study of lumen-apposing metal stents with or without pigtail in endoscopic ultrasound-guided biliary drainage for malignant obstruction-BAMPI TRIAL: an open-label, randomized controlled trial protocol. Garcia Sumalla A, Loras C, Sanchiz V, Sanz R, Vazquez Sequeiros E, Aparicio J, De la Serna Higuera C, Luna Rodriguez D, Andujar X, Capilla M, Barbera T, Foruny Olcina J, Martinez B, Dura M, Salord S, Laquente B, Tebe C, Videla S, Perez-Miranda M, Gornals J. Trials. 2022 Feb 25;23(1):181. doi: 10.1186/s13063-022-06106-1. PMID: 35216619

Nationwide COVID-19-EII study: incidence, environmental risk factors and long-term follow-up of patients with inflammatory bowel disease and COVID-19 of the ENEIDA Registry. Zabana Y, Marin-Jimenez I, Rodriguez-Lago I, et al. Journal of Clinical Medicine. 2022 Jan 14;11(2):421. doi: 10.3390/jcm11020421. PMID: 35054116

Plasma ammonia levels predict hospitalisation with liver-related complications and mortality in clinically stable outpatients with cirrhosis. Tranah T, Ballester M, Carbonell-Asins J, Ampuero J, Alexandrino G, Caracostea A, Sanchez-Torrijos Y, Thomsen K, Kerbert A, Capilla-Lozano M, Romero-Gomez M, Escudero-Garcia D, Montoliu C, Jalan R, Shawcross D. Journal of Hepatology. 2022 Dec;77(6):1554-1563. doi: 10.1016/j.jhep.2022.07.014. PMID: 35872326

Risk factors for COVID-19 in inflammatory bowel disease: a national, ENEIDA-based case-control study (COVID-19-EII). Zabana Y, Marin-Jimenez I, Rodriguez-Lago I, Vera I, Martin-Arranz M, Guerra I, P Gisbert J, Mesonero F, Benitez O, Taxonera C, Ponferrada-Diaz A, Piqueras M, J Lucendo A, Caballol B, Manosa M, Martinez-Montiel P, Bosca-Watts M, Gordillo J, Bujanda L, Mancenido N, Martinez-Perez T, Lopez A, Rodriguez-Gutierrez C, Garcia-Lopez S, Vega P, Rivero M, Melcarne L, Calvo M, Iborra M, Barreiro de Acosta M, Sicilia B, Barrio J, Perez Calle J, Busquets D, Perez-Martinez I, Navarro-Llavat M, Hernandez V, Arguelles-Arias F, Ramirez Esteso F, Meijide S, Ramos L, Gomollon F, Munoz F, Suris G, Ortiz de Zarate J, Huguet J, Llao J, Garcia-Sepulcre M, Sierra M, Dura M, Estrecha S, Fuentes Coronel A, Hinojosa E, Olivan L, Iglesias E, Gutierrez A, Varela P, Rull N, Gilabert P, Hernandez-Camba A, Brotons A, Ginard D, Sese E, Carpio D, Aceituno M, Cabriada J, Gonzalez-Lama Y, Jimenez L, Chaparro M, Lopez-San Roman A, Alba C, Plaza-Santos R, Mena R, Tamarit-Sebastian S, Ricart E, Calafat M, Olivares S, Navarro P, Bertoletti F, Alonso-Galan H, Pajares R, Olcina P, Manzano P, Domenech E, Esteve M, On Behalf Of The Eneida Registry Of Geteccu. Journal of Clinical Medicine. 2022 Dec 19;11(24):7540. doi: 10.3390/jcm11247540. PMID: 36556155

Risk of immunomediated adverse events and loss of response to infliximab in elderly patients with inflammatory bowel disease. A cohort study of the ENEIDA registry. Calafat M, Manosa M, Ricart E, Nos P, Iglesias-Flores E, Vera I, Lopez-SanRoman A, Guardiola J, Taxonera C, Minguez M, Martin-Arranz MD, de Castro L, de Francisco R, Rivero M, Garcia-Planella E, Calvet X, Garcia-Lopez S, Marquez L, Gomollon F, Barrio J, Esteve M, Munoz F, Gisbert JP, Gutierrez A, Hinojosa J, Arguelles-Arias F, Busquets D, Bujanda L, Perez-Calle JL, Sicilia B, Merino O, Martinez P, Bermejo F, Lorente R, Barreiro-de Acosta M, Rodriguez C, Garcia-Sepulcre MF, Monfort D, Canete F, Domenech E. Journal of Crohn’s & Colitis. 2022 Jul 14;16(6):946-953. doi: 10.1093/ecco-jcc/jjab213. PMID: 34864947

Self-expandable metal stents versus endoscopic balloon dilation for the treatment of strictures in Crohn’s disease (ProtDilat study): an open-label, multicentre, randomised trial. Loras C, Andujar X, Gornals JB, Sanchiz V, Brullet E, Sicilia B, Martin Arranz MD, Naranjo A, Barrio J, Duenas C, Foruny JR, Busquets D, Monfort D, Pineda JR, Gonzalez Huix F, Perez Roldan F, Pons V, Gonzalez B, Reyes Moreno J, Sainz E, Guardiola J, Bosca Watts MM, Fernandez Banares F, Mayor V, Esteve M. Lancet. Gastroenterology & Hepatology. 2022 Apr;7(4):332-341. doi: 10.1016/S2468-1253(21)00386-1. PMID: 35065738

Subcutaneous Infliximab [CT-P13], a true biologic 2.0. real clinical practice multicentre study. Huguet JM, Garcia-Lorenzo V, Marti L, Paredes JM, Ramirez JJ, Pastor M, Ruiz L, Sanahuja A, Timoneda P, Sanchis L, Perez GA, Bosca-Watts MM. Biomedicines. 2022 Aug 30;10(9):2130. doi: 10.3390/biomedicines10092130. PMID: 36140230

Thiopurine adherence: high prevalence with low impact in UC outcomes. Gomez-Medina C, Capilla-Lozano M, Ballester Ferre M, Marti-Aguado D, Crespo A, Bosca-Watts M, Navarro Cortes P, Anton R, Pascual Moreno I, Tosca Cuquerella J, Minguez Perez M. Revista Española de Enfermedades Digestivas. 2022 Feb;114(2):76-82. doi: 10.17235/reed.2021.7630/2020. PMID: 33733802

Using interpretable machine learning to identify baseline predictive factors of remission and drug durability in crohn’s disease patients on ustekinumab. Chaparro M, Baston-Rey I, Salgado E, Garcia J, Ramos L, Palomares M, Arguelles-Arias F, Flores E, Cabello M, Iturria S, Ortiz A, Charro M, Ginard D, Sadornil C, Ochoa O, Busquets D, Iyo E, Casbas A, de la Piscina P, Bosca-Watts M, Arroyo M, Garcia M, Hinojosa E, Gordillo J, Montiel P, Jimenez B, Ivorra C, Moron J, Huguet J, Gonzalez-Lama Y, Santos A, Amo V, Arranz M, Bermejo F, Cadilla J, de Celix C, Salazar P, San Roman A, Jimenez N, Garcia-Lopez S, Figuerola A, Jimenez I, Cerezo F, Taxonera C, Varela P, de Francisco R, Monfort D, Arriero G, Hernandez-Camba A, Alonso F, Van Domselaar M, Pajares-Villarroya R, Nunez A, Moranta F, Marin-Jimenez I, Alonso V, Rodriguez M, Camo-Monterde P, Tercero I, Navarro-Llavat M, Garcia L, Cruz D, Kloss S, Passey A, Novella C, Vispo E, Barreiro-de Acosta M, Gisbert J. Journal of Clinical Medicine. 2022 Aug 3;11(15):4518. doi: 10.3390/jcm11154518. PMID: 35956133

Botulinum toxin injection plus topical diltiazem for chronic anal fissure: a randomized double-blind clinical trial and long-term outcome. Herreros B, Espi A, Monton Rodriguez C, Garcia-Granero E, Sanchiz V, Ferriols FL, Almela P, Hernandez V, Mora F, Minguez M. Diseases of the Colon and Rectum. 2021 Dec 1;64(12):1521-1530. doi: 10.1097/DCR.0000000000001983. PMID: 34747917

Caustic ingestion: development and validation of a prognostic score. Tosca J, Villagrasa R, Sanahuja A, Sanchez A, Trejo G, Herreros B, Pascual I, Mas P, Pena A, Minguez M. Endoscopy. 2021 Aug;53(8):784-791. doi: 10.1055/a-1297-0333. PMID: 33096569

Clinical symptoms are correlated with gastrojejunal anastomosis complications only during the first year after laparoscopic Roux-en-Y gastric bypass. Lapena Rodriguez M, Cassinello Fernandez N, Martin Arevalo J, Sanchiz Soler V, Alfonso Ballester R, Ortega Serrano J. Nutricion Hospitalaria. 2021 Oct 13;38(5):978-982. doi: 10.20960/nh.03602. PMID: 34036791

Design and validation of a patient-reported outcome measure scale in acute pancreatitis: the PAN-PROMISE study. de-Madaria E, Sanchez-Marin C, Carrillo I, Vege S, Chooklin S, Bilyak A, Mejuto R, Mauriz V, Hegyi P, Marta K, Kamal A, Lauret-Brana E, Barbu S, Nunes V, Ruiz-Rebollo M, Garcia-Rayado G, Lozada-Hernandez E, Pereira J, Negoi I, Espina S, Hollenbach M, Litvin A, Bolado-Concejo F, Vargas R, Pascual Moreno I, Singh V, Mira J. Gut. 2021 Jan;70(1):139-147. doi: 10.1136/gutjnl-2020-320729. PMID: 32245906

Effectiveness and safety of ustekinumab in ulcerative colitis: Real-world evidence from the ENEIDA registry. Chaparro M, Garre A, Iborra M, Sierra M, Barreiro-de Acosta M, Fernandez-Clotet A, de Castro L, Bosca-Watts M, Casanova M, Lopez-Garcia A, Lorente R, Rodriguez C, Carbajo A, Arroyo M, Gutierrez A, Hinojosa J, Martinez-Perez T, Villoria A, Bermejo F, Busquets D, Camps B, Canete F, Mancenido N, Monfort D, Navarro-Llavat M, Perez-Calle J, Ramos L, Rivero M, Angueira T, Camo P, Carpio D, Garcia-de-la-Filia I, Gonzalez-Munoza C, Hernandez L, Huguet J, Morales V, Sicilia B, Vega P, Vera I, Zabana Y, Nos P, Suarez Alvarez P, Calvino-Suarez C, Ricart E, Hernandez V, Minguez M, Marquez L, Hervias Cruz D, Rubio Iturria S, Barrio J, Gargayo-Puyuelo C, Frances R, Hinojosa E, Del Moral M, Calvet X, Algaba A, Aldeguer X, Guardiola J, Manosa M, Pajares R, Piqueras M, Garcia-Bosch O, Lopez Serrano P, Castro B, Lucendo A, Montoro M, Castro Ortiz E, Mesonero F, Garcia-Planella E, Fuentes D, Bort I, Delgado-Guillena P, Arias L, Iglesias A, Calvo M, Esteve M, Domenech E, Gisbert J. Journal of Crohn’s & colitis. 2021 Nov 8;15(11):1846-1851. doi: 10.1093/ecco-jcc/jjab070. PMID: 33860795

Evaluation of changes in intestinal microbiota in Crohn’s disease patients after anti-TNF alpha treatment. Sanchis-Artero L, Martinez-Blanch JF, Manresa-Vera S, Cortes-Castell E, Valls-Gandia M, Iborra M, Paredes-Arquiola JM, Bosca-Watts M, Huguet JM, Gil-Borras R, Rodriguez-Morales J, Cortes-Rizo X. Scientific Reports. 2021 May 11;11(1):10016. doi: 10.1038/s41598-021-88823-2. PMID: 33976272

Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA Registry. Algaba A, Guerra I, Ricart E, Iglesias E, Manosa M, Gisbert J, Guardiola J, Minguez Pérez M, Castro B, de Francisco R, Nos P, Bertoletti F, Mesonero F, Barrio J, Dolores Martin-Arranz M, Calvet X, Garcia-Lopez S, Sicilia B, Alcain G, Esteve M, Marquez L, Piqueras M, Jimenez L, Perez-Calle J, Bujanda L, Garcia-Sepulcre M, Fernandez A, Moraleja I, Humberto Lorente R, Garcia-Bosch O, Lamban A, Blazquez I, Rodriguez E, Huguet J, Lucendo A, Almela P, Busquets D, Ramirez de la Piscina P, Perez M, Domenech E, Bermejo F, Spanish GETECCU Grp, ENEIDA Project. Digestive Diseases and Sciences. 2021 Jun;66(6):2014-2023. doi: 10.1007/s10620-020-06424-x. PMID: 32671587

Patient-evaluated quality of care is related to better inflammatory bowel disease outcomes: the IQCARO II Project. Calvet X, Casellas F, Saldana R, Carpio D, Minguez M, Vera I, Marin L, Julia B, GETECCU G. Patient. 2021 Sep;14(5):625-634. doi: 10.1007/s40271-021-00500-8. PMID: 33709214

Risk factors and management strategies associated with non-response to aminosalicylates for maintenance treatment in ulcerative colitis. Marti-Aguado D, Ballester M, Minguez M. Revista Espanola de Enfermedades Digestivas. 2021 Jun;113(6):447-453. doi: 10.17235/reed.2021.7797/2021. PMID: 33569968

Surgical treatment of an intraductal papillary mucinous neoplasm of the biliary tract diagnosed by SpyGlass®. Martí Fernandez R, Garces Albir M, Ballester Ferre M, Dorcaratto D, Villagrasa Manzano R, Muñoz Forner E, Gómez Adrián J, Sanchiz Soler V, Sabater Orti L, Ortega Serrano J. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 2021 Jan;113(1):45-47. doi: 10.17235/reed.2020.7122/2020. doi: 10.17235/reed.2020.7122/2020. PMID: 33054282

Ten-year assessment of a cancer fast-track programme to connect primary care with oncology: reducing time from initial symptoms to diagnosis and treatment initiation. Martinez MT, Monton-Bueno J, Simon S, Ortega B, Moragon S, Rosello S, Insa A, Navarro J, Sanmartin A, Julve A, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner MJ, Cano A, Silvestre A, Teruel A, Lluch A, Cervantes A, Chirivella Gonzalez I. ESMO open. 2021 May 11;6(3):100148. doi: 10.1016/j.esmoop.2021.100148. PMID: 33989988

Tofacitinib in ulcerative colitis: real-world evidence from the ENEIDA Registry. Chaparro M, Garre A, Mesonero F, Rodriguez C, Barreiro-de Acosta M, Martinez-Cadilla J, Arroyo M, Mancenido N, Sierra-Ausin M, Vera-Mendoza I, Casanova M, Nos P, Gonzalez-Munoza C, Martinez T, Bosca Watts M, Calafat M, Busquets D, Girona E, Llao J, Martin-Arranz M, Piqueras M, Ramos L, Suris G, Bermejo F, Carbajo A, Casas-Deza D, Fernandez-Clotet A, Garcia M, Ginard D, Gutierrez-Casbas A, Hernandez L, Lucendo A, Marquez L, Merino-Ochoa O, Rancel F, Taxonera C, Lopez Sanroman A, Rubio S, Domenech E, Gisbert J. Journal of Crohn’s & Colitis. 2021 Jan 13;15(1):35-42. doi: 10.1093/ecco-jcc/jjaa145. PMID: 32969471

Transjugular intrahepatic portosystemic shunt reduces hospital care burden in patients with decompensated cirrosis. Ballester M, Lluch P, Gomez C, Capilla M, Tosca J, Marti-Aguado D, Guijarro J, Minguez M. Internal and Emergency Medicine. 2021 Sep;16(6):1519-1527. doi: 10.1007/s11739-020-02602-x. PMID: 33400160

A rare case of acute cholangitis after endoscopic ampullectomy. Ferre M, Sanchiz V, Sabado F, Pena A. Revista Espanola de Enfermedades Digestivas. 2020 Jun;112(6):503-504. doi: 10.17235/reed.2020.6653/2019. PMID: 32450700

Changes in the requirement for early surgery in inflammatory bowel disease in the era of biological agents. Guasch M, Canete F, Ordas I, Iglesias-Flores E, Clos A, Gisbert J, Taxonera C, Vera I, Minguez Pérez M, Guardiola J, Rivero M, Nos P, Gomollon F, Barrio J, de Francisco R, Lopez-Sanroman A, Dolores Martin-Arranz M, Garcia-Planella E, Camargo R, Garcia-Lopez S, de Castro L, Calvet X, Esteve M, Manosa M, Domenech E, GETECCU-ENEIDA Registry. Journal of Gastroenterology and Hepatology. 2020 Dec;35(12):2080-2087. doi: 10.1111/jgh.15084. PMID: 32350906

Clinical assessment of risk factors for infection in inflammatory bowel disease patients. Tosca Cuquerella J, Garcia N, Pascual Moreno I, Bosca Watts M, Anton Ausejo M, Sanahuja Martinez A, Mas Mercader P, Mora Miguel F, Minguez Pérez M. International Journal Of Colorectal Disease. 2020 Mar;35(3):491-500. doi: 10.1007/s00384-019-03501-0. PMID: 31915983

Effectiveness and Safety of the Sequential Use of a Second and Third Anti-TNF Agent in Patients With Inflammatory Bowel Disease: Results From the Eneida Registry. Casanova M, Chaparro M, Minguez Pérez M, Ricart E, Taxonera C, Garcia-Lopez S, Guardiola J, Lopez-San Roman A, Iglesias E, Beltran B, Sicilia B, Vera M, Hinojosa J, Riestra S, Domenech E, Calvet X, Perez-Calle J, Martin-Arranz M, Aldeguer X, Rivero M, Monfort D, Barrio J, Esteve M, Marquez L, Lorente R, Garcia-Planella E, de Castro L, Bermejo F, Merino O, Rodriguez-Perez A, Martinez-Montiel P, Van Domselaar M, Alcain G, Dominguez-Cajal M, Munoz C, Gomollon F, Fernandez-Salazar L, Garcia-Sepulcre M, Rodriguez-Lago I, Gutierrez A, Arguelles-Arias F, Rodriguez C, Rodriguez G, Bujanda L, Llao J, Varela P, Ramos L, Huguet J, Almela P, Romero P, Navarro-Llavat M, Abad A, Ramirez-de la Piscina P, Lucendo A, Sese E, Madrigal R, Charro M, Garcia-Herola A, Pajares R, Khorrami S, Gisbert J. Inflammatory Bowel Diseases. 2020 Mar 4;26(4):606-616. doi: 10.1093/ibd/izz192. PMID: 31504569

Efficacy and safety of endoscopic balloon dilation in inflammatory bowel disease: results of the large multicenter study of the ENEIDA registry (vol 34, pg 1112, 2020). Andujar X, Loras C, Gonzalez B, Socarras M, Sanchiz Soler V, Bosca Watts M, Domenech E, Calafat M, Rodriguez E, Sicilia B, Calvet X, Barrio J, Guardiola J, Iglesias E, Jose Casanova M, Ber Y, Monfort D, Lopez-Sanroman A, Rodriguez-Lago I, Bujanda L, Marquez L, Dolores Martin-Arranz M, Zabana Y, Fernandez-Banares F, Esteve M, ENEIDA Registry GETECCU. Surgical Endoscopy and Other Interventional Techniques. 2020 Mar;34(3):1123. doi: 10.1007/s00464-019-06909-5. PMID: 31144122

Improving Quality of Care in Inflammatory Bowel Disease Through Patients’ Eyes: IQCARO Project. Calvet X, Saldana R, Carpio D, Minguez Pérez M, Vera I, Julia B, Marin L, Casellas F. Inflammatory Bowel Diseases. 2020 Apr 11;26(5):782-791. doi: 10.1093/ibd/izz126. PMID: 31634907

Neoadjuvant treatment for locally advanced unresectable and borderline resectable pancreatic cancer: oncological outcomes at a single academic centre. Rosello S, Pizzo C, Huerta M, Munoz E, Aliaga R, Vera A, Alfaro-Cervello C, Jorda E, Garces-Albir M, Roda D, Dorcaratto D, Tarazona N, Torondel S, Guijarro J, Sanchiz V, Gambardella V, Fleitas-Kanonnikoff T, Lluch P, Pascual I, Ferrandez A, Sabater L, Cervantes A. ESMO Open. 2020 Nov;5(6):e000929. doi: 10.1136/esmoopen-2020-000929. PMID: 33229503

Oxidative and Nitrosative Pattern in Circulating Leukocytes of Very Early/Early Hepatocellular Carcinoma Patients. Lluch P, Segarra G, Tosca J, Navarro L, Navarrete-Navarro J, Herrera G, Sanahuja A, Hernandez S, Lluch S, Medina P. Anticancer Research. 2020 Dec;40(12):6853-6861. doi: 10.21873/anticanres.14707. PMID: 33288577

Patients with Inflammatory bowel disease are not at increased risk of COVID-19: a large multinational cohort study. Allocca M, Chaparro M, Gonzalez H, Bosca Watts M, Palmela C, D’Amico F, Zacharopoulou E, Kopylov U, Ellul P, Bamias G, Ntelis V, Lahat A, Mantzaris G, Papaconstantinou I, Katsanos K, Uspenskaya Y, Christodoulou D, Ben Horin S, Peyrin-Biroulet L, Torres J, Sebastian S, Gisbert J, Danese S, Fiorino G. Journal of Clinical Medicine. 2020 Oct 31;9(11):3533. doi: 10.3390/jcm9113533. PMID: 33142843

Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients. Iborra M, Garcia-Morales N, Rubio S, Bertoletti F, Calvo M, Taxonera C, Bosca Watts M, Sierra M, Mancenido N, Beltran B, Castillejo O, Garcia-Planella E, Vera I, Alba C, Marti Aguado D, Ballester Ferre M, Cano-Sanz N, Pajares-Villarroya R, Cerrillo E, Canada A, Nos P. Scientific Reports. 2020 Oct 20;10(1):17774. doi: 10.1038/s41598-020-73577-0. PMID: 33082359

Recommendations of the Crohn’s Disease and Ulcerative Colitis Spanish Working Group (GETECCU) for the treatment of perianal fistulas of Crohn’s disease. Toledo Bosca M, Alos R, Maroto N, Gisbert J, Beltran B, Chaparro M, Nos P, Minguez Pérez M, Hinojosa J. Gastroenterologia y Hepatologia. 2020 Mar;43(3):155-168. doi: 10.1016/j.gastrohep.2019.09.012. PMID: 31870681

Recommendations of the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis (GETECCU) on topical therapy in ulcerative colitis. Ginard D, Marin-Jimenez I, Barreiro-de Acosta M, Ricart E, Domenech E, Gisbert J, Esteve M, Minguez Pérez M, Representacion GETECCU. Gastroenterologia y Hepatologia. 2020 Feb;43(2):97-105. doi: 10.1016/j.gastrohep.2019.10.004. PMID: 31839219

Switching to a second thiopurine in adult and elderly patients with inflammatory bowel disease: a nationwide study from the ENEIDA registry. Calafat M, Manosa M, Mesonero F, Guardiola J, Minguez Pérez M, Nos P, Vera I, Taxonera C, Iglesias E, Ricart E, Gisbert J, Calvet X, Garcia-Lopez S, Monfort D, Perez Calle J, Riestra S, Gomollon F, Garcia-Planella E, Bermejo F, Vicent H, Martin-Arranz M, Gutierrez A, Torres P, Canete F, Domenech E. Journal of Crohn’s & Colitis. 2020 Sep 16;14(9):1290-1298. doi: 10.1093/ecco-jcc/jjaa055. PMID: 32201893

The development of type-1 autoimmune hepatitis after chronic hepatitis C (HCV) clearance by direct-acting antivirals (DAA). Rodriguez C, Garcia A, Moreno I. Revista Espanola de Enfermedades Digestivas. 2020 Aug;112(8):664-665. doi: 10.17235/reed.2020.6785/2019. PMID: 32686431

Proyectos
Referencia: PI22/01157
Título: Papel de los GPCRS sensores de metabolitos en la enfermedad inflamatoria intestinal: implicación de la microbiota intestinal
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanced FEDER
Investigador principal: Jesus Cosin Roger
Duración: 2023 – 2025
Presupuesto: 111.320 €
Referencia: CIPROM2021/044
Título: Pharmacology of the hepato-gastrointestinal tract: analysis of cellular and molecular targets for the treatment of fibrosis
Entidad Financiadora: Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital
Investigador principal: Juan Vicente Esplugues Mota y María Dolores Barrachina Sancho
Duración: 2022 – 2025
Presupuesto: 539.240 €
+ Información
Título: Fracaso renal agudo en pancreatitis aguda: prevalencia, factores asociados, evolución clínica y utilidad de la cistatina C
Doctorando: Vázquez Fernández, Paola
Director: Mora Miguel, Francisco; Torregrosa Maicas, Isidro Antonio; Pascual Moreno, Isabel
Fecha: 22/11/2021
Universidad: Universitat de València

Título: Impacto de la inmunosuppresión y otros factores de riesgo en el desarrollo de infecciones en pacientes con enfermedad inflamatoria intestinal: estudio caso-control
Doctorando: García Gimeno, Natalia
Director: Mínguez Pérez, Miguel; Tosca Cuquerella, Joan; Mora Miguel, Francisco
Fecha: 05/11/2021
Universidad: Universitat de València