Grupo Clínico Asociado en Medicina Digestiva

Área de

Diagnóstico y tratamiento de la encefalopatía hepática mínima, hepatocarcinoma, hipertensión portal y NASH

Diagnóstico y tratamiento de la patología funcional digestiva

Diagnóstico y tratamiento de patología pancreática

Establecer un equipo de investigación traslacional en patología inflamatoria intestinal, pancreática y hepática

Coordinador
Dr. Miguel Mínguez Pérez
miguel.minguez@uv.es/mminguez@uv.es

INVESTIGADORES
R4 Senior

Miguel Mínguez Pérez    

R3 Consolidado

Isabel Pascual Moreno

R2 Novel / Emergente

Andrés Peña Aldea
Marta Maia Boscá Watts
Marta Ponce Romero
Paloma Lluch García
Vicente Sanchiz Soler
Joan Tosca Cuquerella

R1 Predoctoral
STAFF
Colaborador/a

Ana Sanahuja Martínez
Pablo Navarro Cortés
Pilar Más Mercader
Rosana Villagrasa Manzano
Rosario Antón Ausejo
Sherly Hernández

Enfermero/a

Amparo Ruiz
Nuria Casasús Moya

Técnico/a

Lorena Boronat Cifre

Apoyo
Publicaciones
Autoimmune hepatitis triggered by COVID-19. Monton Rodriguez C, Navarro Cortes P, Lluch Garcia P, Minguez Perez M. Revista Espanola de Enfermedades Digestivas. 2022 Jan;114(1):64-65. doi: 10.17235/reed.2021.8045/2021. PMID: 34015933

Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease. Carrascal M, Areny-Balaguero A, de-Madaria E, Cardenas-Jaen K, Garcia-Rayado G, Rivera R, Martin Mateos R, Pascual-Moreno I, Gironella M, Abian J, Closa D. The Journal of pathology. 2022 Jan;256(1):83-92. doi: 10.1002/path.5811. PMID: 34599510

Botulinum toxin injection plus topical diltiazem for chronic anal fissure: a randomized double-blind clinical trial and long-term outcome. Herreros B, Espi A, Monton Rodriguez C, Garcia-Granero E, Sanchiz V, Ferriols FL, Almela P, Hernandez V, Mora F, Minguez M. Diseases of the Colon and Rectum. 2021 Dec 1;64(12):1521-1530. doi: 10.1097/DCR.0000000000001983. PMID: 34747917

Caustic ingestion: development and validation of a prognostic score. Tosca J, Villagrasa R, Sanahuja A, Sanchez A, Trejo G, Herreros B, Pascual I, Mas P, Pena A, Minguez M. Endoscopy. 2021 Aug;53(8):784-791. doi: 10.1055/a-1297-0333. PMID: 33096569

Clinical symptoms are correlated with gastrojejunal anastomosis complications only during the first year after laparoscopic Roux-en-Y gastric bypass. Lapena Rodriguez M, Cassinello Fernandez N, Martin Arevalo J, Sanchiz Soler V, Alfonso Ballester R, Ortega Serrano J. Nutricion Hospitalaria. 2021 Oct 13;38(5):978-982. doi: 10.20960/nh.03602. PMID: 34036791

Design and validation of a patient-reported outcome measure scale in acute pancreatitis: the PAN-PROMISE study. de-Madaria E, Sanchez-Marin C, Carrillo I, Vege S, Chooklin S, Bilyak A, Mejuto R, Mauriz V, Hegyi P, Marta K, Kamal A, Lauret-Brana E, Barbu S, Nunes V, Ruiz-Rebollo M, Garcia-Rayado G, Lozada-Hernandez E, Pereira J, Negoi I, Espina S, Hollenbach M, Litvin A, Bolado-Concejo F, Vargas R, Pascual Moreno I, Singh V, Mira J. Gut. 2021 Jan;70(1):139-147. doi: 10.1136/gutjnl-2020-320729. PMID: 32245906

Effectiveness and safety of ustekinumab in ulcerative colitis: Real-world evidence from the ENEIDA registry. Chaparro M, Garre A, Iborra M, Sierra M, Barreiro-de Acosta M, Fernandez-Clotet A, de Castro L, Bosca-Watts M, Casanova M, Lopez-Garcia A, Lorente R, Rodriguez C, Carbajo A, Arroyo M, Gutierrez A, Hinojosa J, Martinez-Perez T, Villoria A, Bermejo F, Busquets D, Camps B, Canete F, Mancenido N, Monfort D, Navarro-Llavat M, Perez-Calle J, Ramos L, Rivero M, Angueira T, Camo P, Carpio D, Garcia-de-la-Filia I, Gonzalez-Munoza C, Hernandez L, Huguet J, Morales V, Sicilia B, Vega P, Vera I, Zabana Y, Nos P, Suarez Alvarez P, Calvino-Suarez C, Ricart E, Hernandez V, Minguez M, Marquez L, Hervias Cruz D, Rubio Iturria S, Barrio J, Gargayo-Puyuelo C, Frances R, Hinojosa E, Del Moral M, Calvet X, Algaba A, Aldeguer X, Guardiola J, Manosa M, Pajares R, Piqueras M, Garcia-Bosch O, Lopez Serrano P, Castro B, Lucendo A, Montoro M, Castro Ortiz E, Mesonero F, Garcia-Planella E, Fuentes D, Bort I, Delgado-Guillena P, Arias L, Iglesias A, Calvo M, Esteve M, Domenech E, Gisbert J. Journal of Crohn’s & colitis. 2021 Nov 8;15(11):1846-1851. doi: 10.1093/ecco-jcc/jjab070. PMID: 33860795

Evaluation of changes in intestinal microbiota in Crohn’s disease patients after anti-TNF alpha treatment. Sanchis-Artero L, Martinez-Blanch JF, Manresa-Vera S, Cortes-Castell E, Valls-Gandia M, Iborra M, Paredes-Arquiola JM, Bosca-Watts M, Huguet JM, Gil-Borras R, Rodriguez-Morales J, Cortes-Rizo X. Scientific Reports. 2021 May 11;11(1):10016. doi: 10.1038/s41598-021-88823-2. PMID: 33976272

Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA Registry. Algaba A, Guerra I, Ricart E, Iglesias E, Manosa M, Gisbert J, Guardiola J, Minguez Pérez M, Castro B, de Francisco R, Nos P, Bertoletti F, Mesonero F, Barrio J, Dolores Martin-Arranz M, Calvet X, Garcia-Lopez S, Sicilia B, Alcain G, Esteve M, Marquez L, Piqueras M, Jimenez L, Perez-Calle J, Bujanda L, Garcia-Sepulcre M, Fernandez A, Moraleja I, Humberto Lorente R, Garcia-Bosch O, Lamban A, Blazquez I, Rodriguez E, Huguet J, Lucendo A, Almela P, Busquets D, Ramirez de la Piscina P, Perez M, Domenech E, Bermejo F, Spanish GETECCU Grp, ENEIDA Project. Digestive Diseases and Sciences. 2021 Jun;66(6):2014-2023. doi: 10.1007/s10620-020-06424-x. PMID: 32671587

Management of patients with Intestinal Bowel Disease and COVID-19: a review of current evidence and future perspectives. Suria C, Bosca-Watts MM, Navarro P, Tosca J, Anton R, Sanahuja A, Revaliente M, Minguez M. Gastroenterologia y Hepatología. 2021 Jun 22;S0210-5705(21)00203-X. doi: 10.1016/j.gastrohep.2021.06.005. PMID: 34171421

Patient-evaluated quality of care is related to better inflammatory bowel disease outcomes: the IQCARO II Project. Calvet X, Casellas F, Saldana R, Carpio D, Minguez M, Vera I, Marin L, Julia B, GETECCU G. Patient. 2021 Sep;14(5):625-634. doi: 10.1007/s40271-021-00500-8. PMID: 33709214

Risk factors and management strategies associated with non-response to aminosalicylates for maintenance treatment in ulcerative colitis. Marti-Aguado D, Ballester M, Minguez M. Revista Espanola de Enfermedades Digestivas. 2021 Jun;113(6):447-453. doi: 10.17235/reed.2021.7797/2021. PMID: 33569968

Risk of immunomediated adverse events and loss of response to infliximab in elderly patients with inflammatory bowel disease. A cohort study of the ENEIDA registry. Calafat M, Manosa M, Ricart E, Nos P, Iglesias-Flores E, Vera I, Lopez-SanRoman A, Guardiola J, Taxonera C, Minguez M, Martin-Arranz MD, de Castro L, de Francisco R, Rivero M, Garcia-Planella E, Calvet X, Garcia-Lopez S, Marquez L, Gomollon F, Barrio J, Esteve M, Munoz F, Gisbert JP, Gutierrez A, Hinojosa J, Arguelles-Arias F, Busquets D, Bujanda L, Perez-Calle JL, Sicilia B, Merino O, Martinez P, Bermejo F, Lorente R, Barreiro-de Acosta M, Rodriguez C, Garcia-Sepulcre MF, Monfort D, Canete F, Domenech E. Journal of Crohn’s & Colitis. 2021 Dec 3;jjab213. doi: 10.1093/ecco-jcc/jjab213. PMID: 34864947

Surgical treatment of an intraductal papillary mucinous neoplasm of the biliary tract diagnosed by SpyGlass®. Martí Fernandez R, Garces Albir M, Ballester Ferre M, Dorcaratto D, Villagrasa Manzano R, Muñoz Forner E, Gómez Adrián J, Sanchiz Soler V, Sabater Orti L, Ortega Serrano J. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 2021 Jan;113(1):45-47. doi: 10.17235/reed.2020.7122/2020. doi: 10.17235/reed.2020.7122/2020. PMID: 33054282

Thiopurine adherence: high prevalence with low impact in UC outcomes. Gomez-Medina C, Capilla-Lozano M, Ballester Ferre M, Marti-Aguado D, Crespo A, Bosca-Watts M, Navarro Cortes P, Anton R, Pascual Moreno I, Tosca Cuquerella J, Minguez Perez M. Revista Española de Enfermedades Digestivas. 2021 Mar 18. doi: 10.17235/reed.2021.7630/2020. PMID: 33733802

Tofacitinib in ulcerative colitis: real-world evidence from the ENEIDA Registry. Chaparro M, Garre A, Mesonero F, Rodriguez C, Barreiro-de Acosta M, Martinez-Cadilla J, Arroyo M, Mancenido N, Sierra-Ausin M, Vera-Mendoza I, Casanova M, Nos P, Gonzalez-Munoza C, Martinez T, Bosca Watts M, Calafat M, Busquets D, Girona E, Llao J, Martin-Arranz M, Piqueras M, Ramos L, Suris G, Bermejo F, Carbajo A, Casas-Deza D, Fernandez-Clotet A, Garcia M, Ginard D, Gutierrez-Casbas A, Hernandez L, Lucendo A, Marquez L, Merino-Ochoa O, Rancel F, Taxonera C, Lopez Sanroman A, Rubio S, Domenech E, Gisbert J. Journal of Crohn’s & Colitis. 2021 Jan 13;15(1):35-42. doi: 10.1093/ecco-jcc/jjaa145. PMID: 32969471

Transjugular intrahepatic portosystemic shunt reduces hospital care burden in patients with decompensated cirrosis. Ballester M, Lluch P, Gomez C, Capilla M, Tosca J, Marti-Aguado D, Guijarro J, Minguez M. Internal and Emergency Medicine. 2021 Sep;16(6):1519-1527. doi: 10.1007/s11739-020-02602-x. PMID: 33400160

A rare case of acute cholangitis after endoscopic ampullectomy. Ferre M, Sanchiz V, Sabado F, Pena A. Revista Espanola de Enfermedades Digestivas. 2020 Jun;112(6):503-504. doi: 10.17235/reed.2020.6653/2019. PMID: 32450700

Changes in the requirement for early surgery in inflammatory bowel disease in the era of biological agents. Guasch M, Canete F, Ordas I, Iglesias-Flores E, Clos A, Gisbert J, Taxonera C, Vera I, Minguez Pérez M, Guardiola J, Rivero M, Nos P, Gomollon F, Barrio J, de Francisco R, Lopez-Sanroman A, Dolores Martin-Arranz M, Garcia-Planella E, Camargo R, Garcia-Lopez S, de Castro L, Calvet X, Esteve M, Manosa M, Domenech E, GETECCU-ENEIDA Registry. Journal of Gastroenterology and Hepatology. 2020 Dec;35(12):2080-2087. doi: 10.1111/jgh.15084. PMID: 32350906

Clinical assessment of risk factors for infection in inflammatory bowel disease patients. Tosca Cuquerella J, Garcia N, Pascual Moreno I, Bosca Watts M, Anton Ausejo M, Sanahuja Martinez A, Mas Mercader P, Mora Miguel F, Minguez Pérez M. International Journal Of Colorectal Disease. 2020 Mar;35(3):491-500. doi: 10.1007/s00384-019-03501-0. PMID: 31915983

Effectiveness and Safety of the Sequential Use of a Second and Third Anti-TNF Agent in Patients With Inflammatory Bowel Disease: Results From the Eneida Registry. Casanova M, Chaparro M, Minguez Pérez M, Ricart E, Taxonera C, Garcia-Lopez S, Guardiola J, Lopez-San Roman A, Iglesias E, Beltran B, Sicilia B, Vera M, Hinojosa J, Riestra S, Domenech E, Calvet X, Perez-Calle J, Martin-Arranz M, Aldeguer X, Rivero M, Monfort D, Barrio J, Esteve M, Marquez L, Lorente R, Garcia-Planella E, de Castro L, Bermejo F, Merino O, Rodriguez-Perez A, Martinez-Montiel P, Van Domselaar M, Alcain G, Dominguez-Cajal M, Munoz C, Gomollon F, Fernandez-Salazar L, Garcia-Sepulcre M, Rodriguez-Lago I, Gutierrez A, Arguelles-Arias F, Rodriguez C, Rodriguez G, Bujanda L, Llao J, Varela P, Ramos L, Huguet J, Almela P, Romero P, Navarro-Llavat M, Abad A, Ramirez-de la Piscina P, Lucendo A, Sese E, Madrigal R, Charro M, Garcia-Herola A, Pajares R, Khorrami S, Gisbert J. Inflammatory Bowel Diseases. 2020 Mar 4;26(4):606-616. doi: 10.1093/ibd/izz192. PMID: 31504569

Efficacy and safety of endoscopic balloon dilation in inflammatory bowel disease: results of the large multicenter study of the ENEIDA registry. Andujar X, Loras C, Gonzalez B, Socarras M, Sanchiz Soler V, Bosca Watts M, Domenech E, Calafat M, Rodriguez E, Sicilia B, Calvet X, Barrio J, Guardiola J, Iglesias E, Casanova M, Ber Y, Monfort D, Lopez-Sanroman A, Rodriguez-Lago I, Bujanda L, Marquez L, Martin-Arranz M, Zabana Y, Fernandez-Banares F, Esteve M, ENEIDA registry of GETECCU. Surgical Endoscopy and Other Interventional Techniques. 2020 Mar;34(3):1112-1122. doi: 10.1007/s00464-019-06858-z. PMID: 31144122

Improving Quality of Care in Inflammatory Bowel Disease Through Patients’ Eyes: IQCARO Project. Calvet X, Saldana R, Carpio D, Minguez Pérez M, Vera I, Julia B, Marin L, Casellas F. Inflammatory Bowel Diseases. 2020 Apr 11;26(5):782-791. doi: 10.1093/ibd/izz126. PMID: 31634907

Neoadjuvant treatment for locally advanced unresectable and borderline resectable pancreatic cancer: oncological outcomes at a single academic centre. Rosello S, Pizzo C, Huerta M, Munoz E, Aliaga R, Vera A, Alfaro-Cervello C, Jorda E, Garces-Albir M, Roda D, Dorcaratto D, Tarazona N, Torondel S, Guijarro J, Sanchiz V, Gambardella V, Fleitas-Kanonnikoff T, Lluch P, Pascual I, Ferrandez A, Sabater L, Cervantes A. ESMO Open. 2020 Nov;5(6):e000929. doi: 10.1136/esmoopen-2020-000929. PMID: 33229503

Oxidative and Nitrosative Pattern in Circulating Leukocytes of Very Early/Early Hepatocellular Carcinoma Patients. Lluch P, Segarra G, Tosca J, Navarro L, Navarrete-Navarro J, Herrera G, Sanahuja A, Hernandez S, Lluch S, Medina P. Anticancer Research. 2020 Dec;40(12):6853-6861. doi: 10.21873/anticanres.14707. PMID: 33288577

Patients with Inflammatory bowel disease are not at increased risk of COVID-19: a large multinational cohort study. Allocca M, Chaparro M, Gonzalez H, Bosca Watts M, Palmela C, D’Amico F, Zacharopoulou E, Kopylov U, Ellul P, Bamias G, Ntelis V, Lahat A, Mantzaris G, Papaconstantinou I, Katsanos K, Uspenskaya Y, Christodoulou D, Ben Horin S, Peyrin-Biroulet L, Torres J, Sebastian S, Gisbert J, Danese S, Fiorino G. Journal of Clinical Medicine. 2020 Oct 31;9(11):3533. doi: 10.3390/jcm9113533. PMID: 33142843

Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients. Iborra M, Garcia-Morales N, Rubio S, Bertoletti F, Calvo M, Taxonera C, Bosca Watts M, Sierra M, Mancenido N, Beltran B, Castillejo O, Garcia-Planella E, Vera I, Alba C, Marti Aguado D, Ballester Ferre M, Cano-Sanz N, Pajares-Villarroya R, Cerrillo E, Canada A, Nos P. Scientific Reports. 2020 Oct 20;10(1):17774. doi: 10.1038/s41598-020-73577-0. PMID: 33082359

Recommendations of the Crohn’s Disease and Ulcerative Colitis Spanish Working Group (GETECCU) for the treatment of perianal fistulas of Crohn’s disease. Toledo Bosca M, Alos R, Maroto N, Gisbert J, Beltran B, Chaparro M, Nos P, Minguez Pérez M, Hinojosa J. Gastroenterologia y Hepatologia. 2020 Mar;43(3):155-168. doi: 10.1016/j.gastrohep.2019.09.012. PMID: 31870681

Recommendations of the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis (GETECCU) on topical therapy in ulcerative colitis. Ginard D, Marin-Jimenez I, Barreiro-de Acosta M, Ricart E, Domenech E, Gisbert J, Esteve M, Minguez Pérez M, Representacion GETECCU. Gastroenterologia y Hepatologia. 2020 Feb;43(2):97-105. doi: 10.1016/j.gastrohep.2019.10.004. PMID: 31839219

Switching to a second thiopurine in adult and elderly patients with inflammatory bowel disease: a nationwide study from the ENEIDA registry. Calafat M, Manosa M, Mesonero F, Guardiola J, Minguez Pérez M, Nos P, Vera I, Taxonera C, Iglesias E, Ricart E, Gisbert J, Calvet X, Garcia-Lopez S, Monfort D, Perez Calle J, Riestra S, Gomollon F, Garcia-Planella E, Bermejo F, Vicent H, Martin-Arranz M, Gutierrez A, Torres P, Canete F, Domenech E. Journal of Crohn’s & Colitis. 2020 Sep 16;14(9):1290-1298. doi: 10.1093/ecco-jcc/jjaa055. PMID: 32201893

The development of type-1 autoimmune hepatitis after chronic hepatitis C (HCV) clearance by direct-acting antivirals (DAA). Rodriguez C, Garcia A, Moreno I. Revista Espanola de Enfermedades Digestivas. 2020 Aug;112(8):664-665. doi: 10.17235/reed.2020.6785/2019. PMID: 32686431

+ Información
Título: Impacto de la inmunosuppresión y otros factores de riesgo en el desarrollo de infecciones en pacientes con enfermedad inflamatoria intestinal: estudio caso-control
Doctorando: García Gimeno, Natalia
Director: Mínguez, Miguel; Mora, Francisco; Tosca, Joan
Fecha: 05/11/2021
Universidad: Universitat de València