Grupo de Investigación Traslacional en Cardiopatía Isquémica

Área de Cardiovascular

A partir de nuestra experiencia investigadora de los últimos años en el campo clínico y experimental relacionado con la cardiopatía isquémica, nuestro objetivo actual es enfocarnos en un enfoque traslacional

En 2020 continuamos dilucidando las anomalías en la circulación coronaria tras un infarto de miocardio utilizando un modelo porcino. Además, también hemos comenzado a evaluar in vitro el papel de la lesión endotelial tras la reperfusión coronaria y la implicación de la angiogénesis en la recuperación de la microvasculatura tras un infarto de miocardio en modelos animales y en pacientes.

También hemos desarrollado nuevas herramientas para estudiar pacientes con infarto de miocardio con elevación del segmento ST mediante resonancia magnética cardíaca

Coordinador
Dr. Vicente Bodí Peris
vicente.bodi@uv.es/vijobope@uv.es

INVESTIGADORES
R4 Senior

Vicente Bodí Peris    

R3 Consolidado

Amparo Ruiz Saurí

R2 Novel / Emergente

Clara Bonanad Lozano
José Gavara Doñate

R1 Predoctoral

César Ríos Navarro
Víctor Marcos Garcés
Elena de Dios Lluch

STAFF
Colaborador/a

Paolo Racugno

Enfermero/a

Nerea Pérez Solé

Técnico/a
Apoyo
Publicaciones
Anomalous right coronary artery from the left sinus with interarterial course. Marcos Garcés V, Lorenzo Hernández M, Martínez Más M, Parrilla Muñoz C, Pernias Escrig V, Bodí Peris V. Coronary Artery Disease. 2021 Mar 1. doi: 10.1097/MCA.0000000000000941. PMID: 32804784

Antigen carbohydrate 125 as a biomarker in heart failure: a narrative review. Nunez J, de la Espriella R, Minana G, Santas E, Llacer P, Nunez E, Palau P, Bodi V, Chorro F, Sanchis J, Lupon J, Bayes-Genis A. European Journal of Heart Failure. 2021 Jul 9. doi: 10.1002/ejhf.2295. PMID: 34241936

Atrial fibrillation in patients with COVID-19. Usefulness of the CHA2DS2-VASc score: an analysis of the international HOPE COVID-19 registry. Uribarri A, Nunez-Gil I, Aparisi A, Arroyo-Espliguero R, Eid C, Romero R, Becerra-Munoz V, Feltes G, Molina M, Garcia-Aguado M, Cerrato E, Capel-Astrua T, Alfonso-Rodriguez E, Castro-Mejia A, Raposeiras-Roubin S, Espejo C, Perez-Sole N, Bardaji A, Marin F, Fabregat-Andres O, D’ascenzo F, Santoro F, Akin I, Estrada V, Fernandez-Ortiz A, Macaya C, en representacion de los investigadores del HOPE COVID-19. Revista Espanola de Cardiologia. 2021 Mar 2. doi: 10.1016/j.recesp.2020.12.014. PMID: 33678938

Atrial fibrillation in patients with COVID-19. Usefulness of the CHA2DS2-VASc score: an analysis of the international HOPE COVID-19 registry. Uribarri A, Nunez-Gil I, Aparisi A, Arroyo-Espliguero R, Maroun Eid C, Romero R, Becerra-Munoz V, Feltes G, Molina M, Garcia-Aguado M, Cerrato E, Capel-Astrua T, Alfonso-Rodriguez E, Castro-Mejia A, Raposeiras-Roubin S, Espejo C, Perez-Sole N, Barjardi A, Marin F, Fabregat-Andres O, D’ascenzo F, Santoro F, Akin I, Estrada V, Fernandez-Ortiz A, Macaya C, HOPE COVID-19 investigators. Revista Espanola de Cardiología. 2021 Jan 13;S1885-5857(21)00001-3. doi: 10.1016/j.rec.2020.12.009. PMID: 33583755

Automatic left ventricle volume calculation with explainability through a deep learning weak-supervision methodology. Perez-Pelegri M, Monmeneu J, Lopez-Lereu M, Perez-Pelegri L, Maceira A, Bodi V, Moratal D. Computer Methods and Programs in Biomedicine. 2021 Sep;208:106275. doi: 10.1016/j.cmpb.2021.106275. PMID: 34274609

Bacterial metabolites trimethylamine N-oxide and butyrate as surrogates of small intestinal bacterial overgrowth in patients with a recent decompensated heart failure. Mollar A, Marrachelli V, Nunez E, Monleon D, Bodi V, Sanchis J, Navarro D, Nunez J. Scientific reports. 2021 Mar 17;11(1):6110. doi: 10.1038/s41598-021-85527-5. PMID: 33731747

Clinical utility of antigen carbohydrate 125 for planning the optimal length of stay in acute heart failure. Lorenzo M, Palau P, Llacer P, Dominguez E, Ventura B, Nunez G, Minana G, Solsona J, Santas E, De La Espriella R, Bodi V, Nunez E, Sanchis J, Bayes-Genis A, Nunez J. European Journal of Internal Medicine. 2021 Jun 12;S0953-6205(21)00196-5. doi: 10.1016/j.ejim.2021.05.037. PMID: 34130879

Coronary Revascularization and Long-Term Survivorship in Chronic Coronary Syndrome. Gabaldon-Perez A, Marcos-Garces V, Gavara J, Rios-Navarro C, Minana G, Bayes-Genis A, Husser O, Sanchis J, Nunez J, Chorro F, Bodi V. Journal of Clinical Medicine. 2021 Feb 5;10(4):610. doi: 10.3390/jcm10040610. PMID: 33562869

Early urinary sodium trajectory and risk of adverse outcomes in acute heart failure and renal dysfunction. De La Espriella Juan R, Nuñez Benito E, Llàcer P, Garcia Blas S, Ventura Haro S, Núñez J, Sánchez R, Facila De La Esperanza R, Vaquer Santamaria J, Bodí Peris V, Santas Olmeda E, Miñana Escriva G, Mollar Fernandez A, Núñez Marín G, Chorro Gascó F, Górriz Teruel J, Sanchis Fores J, Bayés-Genis A, Nuñez Villota J. Revista Espanola de Cardiologia (English ed.). 2021 Jul;74(7):616-623. doi: 10.1016/j.rec.2020.06.004. PMID: 32624444

EpCAM and microvascular obstruction in patients with STEMI: a cardiac magnetic resonance study. Rios-Navarro C, Gavara J, Nunez J, Revuelta-Lopez E, Monmeneu JV, Lopez-Lereu MP, de Dios E, Perez-Sole N, Vila JM, Oltra R, Chorro FJ, Bayes-Genis A, Bodi V. Revista Espanola de Cardiologia (English ed.). 2021 May 24;S1885-5857(21)00135-3. doi: 10.1016/j.rec.2021.04.006. PMID: 34045168

Homocysteine and long-term recurrent infarction following an acute coronary síndrome. Miñana Escriva G, Gil Cayuela C, Facila De La Esperanza R, Bodí Peris V, Valero Picher E, Mollar Fernandez A, Marco M, Garcia-Ballester T, Zorio B, Marti-Cervera J, Nuñez Benito E, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Cardiology Journal. 2021;28(4):598-606. doi: 10.5603/CJ.a2020.0170. PMID: 33346372

Hypoplasia of the posterior mitral valve leaflet: Don’t forget to look beyond the mitral valve. Gabaldón-Pérez A, Marcos-Garcés V, Muñoz Gil J, Chorro Gascó FJ, Santas E. Echocardiography. 2021 Jan;38(1):142-143. doi: 10.1111/echo.14910. PMID: 33107084

Identification to cardiac conduction cells in humans and pigs according to their zonal distribution, using histological, immunohistochemical and morphometric study. Gomez-Torres F, Estupinan HY, Ruiz-Sauri A. Research in Veterinary Science. 2021 Jun 9;138:137-147. doi: 10.1016/j.rvsc.2021.06.008. PMID: 34144281

Immunoglobulin G4-related aortitis and severe aortic valve stenosis treated with transcatheter aortic valve replacement and immunosuppression. Viana D, Marcos-Garces V, Blas S, Fores J, Romano J, Baena J, Giner M, Suarez N, Chorro F, Fornas F. Canadian Journal of Cardiology. 2021 Jul 29;S0828-282X(21)00414-1. doi: 10.1016/j.cjca.2021.07.015. PMID: 34333027

Improving the cementation of the tibial component in knee arthroplasty: a study of four techniques in the cadaver. Rodriguez-Collell J, Mifsut D, Ruiz-Sauri A, Rodriguez-Pino L, Gonzalez-Soler E, Valverde-Navarro A. Bone & Joint Research. 2021 Aug;10(8):467-473. doi: 10.1302/2046-3758.108.BJR-2020-0524.R1. PMID: 34340533

Ischemia-reperfusion injury to coronary arteries: comprehensive microscopic study after reperfused myocardial infarction. Rios-Navarro C, Daugbouche-Rubio N, Gavara J, de Dios E, Perez N, Vila JM, Chorro FJ, Ruiz-Sauri A, Bodi V. Annals of Anatomy. 2021 Jun 15;151785. doi: 10.1016/j.aanat.2021.151785. PMID: 34144157

Long-term prognostic implications of revascularization in patients with known or suspected chronic coronary syndromes without ischemia in vasodilator stress cardiovascular magnetic resonance. Minana G, Nunez J, Marcos-Garces V, Gavara J, Rios-Navarro C, Bodi V. International Journal of Cardiology. 2021 Apr 23;S0167-5273(21)00673-2. doi: 10.1016/j.ijcard.2021.04.037. PMID: 33895211

Long-Term Prognostic Value of Cognitive Impairment on Top of Frailty in Older Adults after Acute Coronary Syndrome. Sanchis J, Bonanad C, Garcia-Blas S, Ruiz V, Fernandez-Cisnal A, Sastre C, Ruescas A, Valero E, Gonzalez J, Mollar A, Minana G, Nunez J. Journal of Clinical Medicine. 2021 Jan 24;10(3):444. doi: 10.3390/jcm10030444. PMID: 33498816

Longitudinal strain in remote non-infarcted myocardium by tissue tracking CMR: characterization, dynamics, structural and prognostic implications. GAVARA DOÑATE J, Rodriguez-Palomares J, Rios Navarro C, Valente F, Monmeneu J, Lopez-Lereu M, Ferreira-Gonzalez I, Garcia Del Blanco B, Otaegui I, Canoves Femenia J, De Dios Lluch E, Pérez Solé N, Racugno P, Bonanad Lozano C, Miñana Escriva G, Marcos Garcés V, Barrabes J, Evangelista A, Moratal D, Bayes-Genis A, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. The International Journal Of Cardiovascular Imaging. 2021 Jan;37(1):241-253. doi: 10.1007/s10554-020-01890-w. PMID: 32488452

Magnetic resonance assessment of left ventricular ejection fraction at any time post-infarction for prediction of subsequent events in a large multicenter STEMI Registry. Gavara J, Marcos-Garces V, Lopez-Lereu, MP, Monmeneu JV, Rios-Navarro C, de Dios E, Perez N, Merenciano H, Gabaldon A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Nunez E, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Rodriguez-Palomares JF, Ortiz-Perez JT, Bodi V. Journal of Magnetic Resonance Imaging. 2021 Jun 16. doi: 10.1002/jmri.27789. PMID: 34137478

Main challenges of electrolyte imbalance in older patients with coronavirus disease and risk of QT prolongation. Response. Bonanad C, Diez-Villanueva P, Garcia-Blas S, Martinez-Selles M. Revista Espanola de Cardiologia. 2021 Feb;74(2):199-200. doi: 10.1016/j.recesp.2020.08.014. PMID: 32982010

Morphological variations of the conduction system in the atrioventricular zone and its clinical relationship in different species. Gomez-Torres F, Ballesteros-Acuna L, Ruiz Sauri A. Anatomical Science International. 2021 Mar;96(2):212-220. doi: 10.1007/s12565-020-00575-7. PMID: 32997266

Optimization of a decellularization protocol of porcine tracheas. Long-term effects of cryopreservation. A histological study. Milian L, Sancho-Tello M, Roig-Soriano J, Foschini G, Martinez-Hernandez NJ, Mas-Estelles J, Ruiz-Sauri A, Zurriaga J, Carda C, Mata M. The International Journal of Artificial Organs. 2021 Apr 16;3913988211008912. doi: 10.1177/03913988211008912. PMID: 33863248

Overexpression of genes involved in lymphocyte activation and regulation are associated with reduced CRM-derived cardiac remodelling after STEMI. de Dios E, Rios-Navarro C, Perez-Sole N, Gavara J, Marcos-Garces V, Forteza M, Oltra R, Vila J, Chorro F, Bodi V. International Immunopharmacology. 2021 Mar 4;95:107490. doi: 10.1016/j.intimp.2021.107490. PMID: 33677257

Right ventricular function and iron deficiency in acute heart failure. Miñana Escriva G, Santas Olmeda E, De La Espriella Juan R, Nunez E, Lorenzo Hernández M, Núñez Marín G, Valero Picher E, Bodí Peris V, Chorro Gascó F, Sanchis Fores J, Cohen-Solal A, Bayes-Genis A, Nuñez Villota J. European heart journal. Acute cardiovascular care. 2021 May 25;10(4):406-414. doi: 10.1093/ehjacc/zuaa028. PMID: 33620455

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

Sex differences on new-onset heart failure in patients with known or suspected coronary artery disease. Nunez J, Lorenzo M, Minana G, Palau P, Monmeneu JV, Lopez-Lereu MP, Gavara J, Marcos-Garces V, Rios-Navarro C, Perez N, de Dios E, Nunez E, Sanchis J, Chorro FJ, Bayes-Genis A, Bodi V. European Journal of Preventive Cardiology. 2021 May 10;zwab078. doi: 10.1093/eurjpc/zwab078. PMID: 33970216

Stratification and management of cardiovascular risk in cancer patients. A consensus document of the SEC, FEC, SEOM, SEOR, SEHH, SEMG, AEEMT, AEEC, and AECC. Martin. Garcia A, Mitroi C, Mazon Ramos P, Garcia Sanz R, Virizuela J, Arenas M, Egocheaga Cabello I, Albert D, Anguita Sanchez M, Arrarte Esteban V, Ayala de la Pena F, Bonanand Lozano C, Castro A, Castro Fernandez A, Cordoba R, Cosin-Sales J, Chaparro-Munoz M, Dalmau R, Drak Hernandez Y, Deiros Bronte L, Diez-Villanueva P, Escobar Cervantes C, Fernandez Redondo C, Garcia Rodriguez E, Lozano T, Marco Vera P, Martinez Monzonis A, Mesa D, Oristrell G, Palma Gamiz J, Pedreira M, Reinoso-Barbero L, Rodriguez I, Serrano Antolin J, Toral B, Torres Royo L, Velasco Del Castillo S, Vicente-Herrero T, Zatarain-Nicolas E, Tamargo J, Lopez Fernandez T. Revista Española de Cardiología (English ed.). 2021 Mar 9;S1885-5857(21)00054-2. doi: 10.1016/j.rec.2020.11.020. PMID: 33712348

Suspected Kawasaki disease diagnosed in the adulthood. Severe sequelae in the coronary arteries. Lorenzo-Hernandez M, Marcos-Garces V, Lopez-Fornas F, Valero E, Bodi V, Chorro F. Coronary Artery Disease. 2021 Feb 12. doi: 10.1097/MCA.0000000000001029. PMID: 33587361

Telematic cardiology consultation in the elderly. The 5M framework can help. Diez-Villanueva P, Bonanad C, Ariza-Sole A, Martinez-Selles M. Revista Espanola de Cardiologia. 2021 Jan;74(1):116-117. doi: 10.1016/j.recesp.2020.08.024. PMID: 32994661

The influence of sex and body mass index on the association between soluble neprilysin and risk of heart failure hospitalizations. Nunez J, Nunez E, Revuelta-Lopez E, Minana G, Barallat J, Bodi V, Sanchis J, Aimo A, Emdin M, Lupon J, Husser O, Bayes-Genis A. Scientific reports. 2021 Mar 15;11(1):5940. doi: 10.1038/s41598-021-85490-1. PMID: 33723360

Unraveling the thread of uncontrolled immune response in COVID-19 and STEMI: an emerging need for knowledge sharing. Rios-Navarro C, de Dios E, Forteza MJ, Bodi V. American Journal of Physiology-Heart and Circulatory Physiology. 2021 Jun 1;320(6):H2240-H2254. doi: 10.1152/ajpheart.00934.2020. PMID: 33844596

A Novel Clinical and Stress Cardiac Magnetic Resonance (C-CMR-10) Score to Predict Long-Term All-Cause Mortality in Patients with Known or Suspected Chronic Coronary Syndrome. Marcos Garcés V, Gavara Doñate J, Monmeneu J, Lopez-Lereu M, Pérez Solé N, Rios Navarro C, De Dios Lluch E, Moratal D, Miñana Escriva G, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. Journal of Clinical Medicine. 2020 Jun 23;9(6):1957. doi: 10.3390/jcm9061957. PMID: 32585832

A randomized controlled trial on carbohydrate antigen 125-guided diuretic treatment versus usual care in patients with acute heart failure and renal dysfunction. Nuñez Villota J, Llacer P, Garcia Blas S, Bonanad Lozano C, Ventura S, Nunez J, Sanchez R, Facila De La Esperanza R, De La Espriella Juan R, Vaquer Santamaria J, Cordero A, Roque M, Chamorro C, Bodí Peris V, Valero Picher E, Santas Olmeda E, Del Carmen Moreno M, Miñana Escriva G, Carratalá Calvo A, Rodriguez Borja E, Mollar Fernandez A, Palau P, Bosch M, Bertomeu-Gonzalez V, Lupon J, Navarro Perez J, Chorro Gascó F, Górriz Teruel J, Sanchis Fores J, Voors A, Bayes-Genis A, IMPROVE-HF Investigators. American Journal of Medicine. 2020 Mar;133(3):370-380.e4. doi: 10.1016/j.amjmed.2019.07.041. PMID: 31422111

CA125 outperforms NT-proBNP in acute heart failure with severe tricuspid regurgitation. Soler Costa M, Miñana Escriva G, Santas Olmeda E, Nuñez Benito E, De La Espriella Juan R, Valero Picher E, Bodí Peris V, Chorro Gascó F, Fernández Cisnal A, D’ascoli G, Marti-Cervera J, Sanchis Fores J, Bayes-Genis A, Nuñez Villota J. International Journal of Cardiology. 2020 Jun 1;308:54-59. doi: 10.1016/j.ijcard.2020.03.027. PMID: 32209267

Cardiac sarcoidosis as an incidental finding: A case report. Gabaldon-Perez A, Garcia-Blas S, Forner M, Lopez-Lereu M, Bonanad C. Heart & Lung. 2020;49(6):783-787. doi: 10.1016/j.hrtlng.2020.09.009. PMID: 32980628

Clinical profile and 1-year clinical outcomes of super elderly patients admitted with acute heart failure. Lorenzo Hernández M, De La Espriella Juan R, Miñana Escriva G, Núñez Marín G, Santas Olmeda E, Nuñez Benito E, Heredia Cambra R, Mollar Fernandez A, Civera Gómez J, Villaescusa Capilla M, Sastre Arbona C, Conesa Bona A, Bonanad Lozano C, Bayes-Genis A, Nuñez Villota J. European Journal of Internal Medicine. 2020 Nov;81:78-82. doi: 10.1016/j.ejim.2020.05.017. PMID: 32553586

Clinical Role of CA125 in WorseningHeartFailure: A BIOSTAT-CHF Study Subanalysis. NUÑEZ VILLOTA J, Bayes-Genis A, Revuelta-Lopez E, Ter Maaten J, Miñana Escriva G, Barallat J, Cserkoova A, Bodí Peris V, Fernández Cisnal A, Nuñez Benito E, Sanchis Fores J, Lang C, Ng L, Metra M, Voors A. JACC. Heart failure. 2020 May;8(5):386-397. doi: 10.1016/j.jchf.2019.12.005. PMID: 32171764

Co-loading of finasteride and baicalin in phospholipid vesicles tailored for the treatment of hair disorders. Mir-Palomo S, Nacher A, Ofelia Vila-Buso MA, Caddeo C, Manca ML, Ruiz Sauri A, Escribano Ferrer E, Manconi M, Diez Sales O. Nanoscale. 2020 Aug 6;12(30):16143-16152. doi: 10.1039/d0nr03357j. PMID: 32700723

Consensus document and recommendations on palliative care in heart failure of the Heart Failure and Geriatric Cardiology Working Groups of the Spanish Society of Cardiology. Garcia Pinilla J, Diez-Villanueva P, Bover Freire R, Formiga F, Cobo Marcos M, Bonanad Lozano C, Crespo Leiro M, Ruiz Garcia J, Diaz Molina B, Enjuanes Grau C, Garcia L, Rexach L, Esteban A, Martinez-Selles M. Revista espanola de Cardiologia (English ed.). 2020 Jan;73(1):69-77. doi: 10.1016/j.rec.2019.06.019. PMID: 31761573

Coronavirus: the geriatric emergency of 2020. Joint document of the Geriatric Cardiology Section of the Spanish Society of Cardiology and the Spanish Society of Geriatrics and Gerontology. Bonanad Lozano C, Garcia Blas S, Tarazona-Santabalbina F, Diez-Villanueva P, Ayesta A, SANCHIS FORES J, Vidan-Austiz M, Formiga F, Ariza-Sole A, Martinez-Selles M. Revista Espanola de Cardiologia (English ed.). 2020 Jul;73(7):569-576. doi: 10.1016/j.recesp.2020.03.027. PMID: 32292226

Coronavirus: The Geriatric Emergency of 2020. Joint Document of the Section on Geriatric Cardiology of the Spanish Society of Cardiology and the Spanish Society of Geriatrics and Gerontology. Bonanad C, García-Blas S, Tarazona-Santabalbina FJ, Díez-Villanueva P, Ayesta A, Sanchis Forés J, Vidán-Austiz MT, Formiga F, Ariza-Solé A, Martínez-Sellés M, Scientific societies of the authors. The contributing authors are members of the following scientific bodies. Revista espanola de cardiologia (English ed.). 2020 Jul;73(7):569-576. doi: 10.1016/j.rec.2020.05.001. PMID: 32446793

Early reductive stress and late onset overexpression of antioxidant enzymes in experimental myocardial infarction. Carretero Martínez A, Gomez Cabrera M, Rios Navarro C, Salvador Pascual A, Bodí Peris V, Viña Ribes J. Free Radical Research. 2020 Mar;54(2-3):173-184. doi: 10.1080/10715762.2020.1735632. PMID: 32103692

Early Spot Urinary Sodium and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction. Miñana Escriva G, Llacer P, Sanchis I, Garcia Blas S, Bonanad Lozano C, Ventura S, Sanchez R, De La Espriella Juan R, Bodí Peris V, Facila De La Esperanza R, Mollar Fernandez A, Sanchis Fores J, Bayes-Genis A, Chorro Gascó F, Nuñez Villota J. CardioRenal Medicine. 2020;10(5):362-372. doi: 10.1159/000508178. PMID: 32721973

Effect of insulin on readmission for heart failure following a hospitalization for acute heart failure. Bertomeu-Gonzalez V, Facila L, Palau Sampio P, Miñana Escriva G, Núñez Marín G, De La Espriella Juan R, Santas Olmeda E, Nunez E, Bodí Peris V, Chorro Gascó F, Cordero A, Sanchis Fores J, Lupon J, Bayes-Genis A, Nuñez Villota J. Esc Heart Failure. 2020 Aug 13;7(6):3320-3328. doi: 10.1002/ehf2.12944. PMID: 32790113

Ejection Fraction by Echocardiography for a Selective Use of Magnetic Resonance After Infarction. Marcos-Garces V, Gavara J, Lopez-Lereu M, Monmeneu J, Rios-Navarro C, de Dios E, Perez N, Canoves J, Gonzalez J, Minana G, Nunez J, de la Espriella R, Santas E, Moratal D, Chorro F, Valente F, Lorenzatti D, Rodriguez-Palomares J, Ortiz-Perez J, Bodi V. Circulation. Cardiovascular Imaging. 2020 Dec;13(12):e011491. doi: 10.1161/CIRCIMAGING.120.011491. PMID: 33297764

Factors associated with plasma antigen carbohydrate 125 and amino-terminal pro-B-type natriuretic peptide concentrations in acute heart failure. Miñana Escriva G, De La Espriella Juan R, Mollar Fernandez A, Santas Olmeda E, Nuñez Benito E, Valero Picher E, Bodí Peris V, Chorro Gascó F, Fernández Cisnal A, Marti-Cervera J, Sanchis Fores J, Bayes Genis A, Nuñez Villota J. European Heart Journal-Acute Cardiovascular Care. 2020 Aug;9(5):437-447. doi: 10.1177/2048872620908033. PMID: 32129669

Impact of Diabetes Mellitus and Frailty on Long-Term Outcomes in Elderly Patients with Acute Coronary Syndromes. Rodriguez-Queralto O, Formiga F, Carol A, Llibre C, Martinez-Selles M, Marin F, Diez-Villanueva P, Sanchis J, Bonanad C, Corbi M, Aboal J, Perez-Rivera J, Alegre O, Bernal E, Vicent L, Ariza-Sole A. Journal of Nutrition Health & Aging. 2020;24(7):723-729. doi: 10.1007/s12603-020-1409-1. PMID: 32744568

Innovative strategies to treat skin wounds with mangiferin: fabrication of transfersomes modified with glycols and mucin. Allaw M, Pleguezuelos Villa M, Manca ML, Caddeo C, Aroffu M, Nacher A, Diez Sales O, Ruiz Sauri A, Escribano Ferrer E, Fadda AM, Manconi M. Nanomedicine. 2020 Jul;15(17):1671-1685. doi: 10.2217/nnm-2020-0116. PMID: 32677507

Interstitial changes after reperfused myocardial infarction in swine: morphometric and genetic analysis. Rios Navarro C, Ortega M, Marcos Garcés V, Gavara Doñate J, De Dios Lluch E, Pérez Solé N, Chorro Gascó F, Bodí Peris V, Ruiz Sauri A. BMC Veterinary Research. 2020 Jul 29;16(1):262. doi: 10.1186/s12917-020-02465-6. PMID: 32727469

Lipoprotein(a) and long-term recurrent infarction after an episode of ST-segment elevation acute myocardial infarction. Miñana Escriva G, Gil-Cayuela C, Bodí Peris V, De La Espriella Juan R, Valero Picher E, Mollar Fernandez A, Marco M, Garcia-Ballester T, Zorio B, Fernández Cisnal A, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Coronary Artery Disease. 2020 Jun;31(4):378-384. doi: 10.1097/MCA.0000000000000852. PMID: 32040026

Long-term outcome of patients with NSTEMI and nonobstructive coronary arteries by different angiographic subtypes. Garcia-Blas S, Gonzalez D’Gregorio J, Bonanad C, Fernandez-Cisnal A, Valero E, Minana G, Mollar A, Nunez J, Sanchis J. Revista Espanola De Cardiologia (english Ed.). 2020 Dec 18;S1885-5857(20)30488-6. doi: 10.1016/j.rec.2020.10.008. PMID: 33349589

Main challenges of electrolyte imbalance in older patients with coronavirus disease and risk of QT prolongation. Response. Bonanad C, Diez-Villanueva P, Garcia-Blas S, Martinez-Selles M. Revista Espanola de Cardiologia (English ed.). 2020 Oct 1;S1885-5857(20)30420-5. doi: 10.1016/j.rec.2020.08.018. PMID: 33069612

Mangiferin glycethosomes as a new potential adjuvant for the treatment of psoriasis. Pleguezuelos Villa M, Diez Sales O, Manca ML, Manconi M, Ruiz Sauri A, Escribano Ferrer E, Nacher A. International Journal of Pharmaceutics. 2020 Jan 5;573:118844. doi: 10.1016/j.ijpharm.2019.118844. PMID: 31751638

Melatonin, coronavirus, cardiovascular disease, and the geriatric emergency: let’s use everything we have! Response. García-Blas S, Díez-Villanueva P, Tarazona-Santabalbina F, Bonanad C. Revista Espanola de Cardiologia (English ed.). 2020 Dec;73(12):1082. doi: 10.1016/j.recesp.2020.06.019. PMID: 32836658

Milestones of the Section on Geriatric Cardiology of the Spanish Society of Cardiology: the r-evolution from 1995 to 2020. Bonanad C, Guerrero C, Bianchi C. Revista Espanola de Cardiologia (English ed.). 2020 Dec;73(12):981-984. doi: 10.1016/j.rec.2020.06.028. PMID: 32798150

Milestones of the Section on Geriatric Cardiology of the Spanish Society of Cardiology: the r-evolution from 1995 to 2020. Bonanad C, Guerrero C, Bianchi C. Revista Espanola de Cardiologia (English ed.). 2020 Dec;73(12):981-984. doi: 10.1016/j.recesp.2020.06.004. PMID: 32836660

Morphometry and comparative histology of sinus and atrioventricular nodes in humans and pigs and their relevance in the prevention of nodal arrhythmias. Gomez-Torres F, Sebastian R, Ruiz Sauri A. Research In Veterinary Science. 2020 Feb;128:275-285. doi: 10.1016/j.rvsc.2019.12.008. PMID: 31869593

Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron: The Myocardial-IRON Trial. Nuñez Villota J, Miñana Escriva G, Cardells Beltran I, Palau P, Llacer P, Facila L, Almenar L, Lopez Lereu M, Monmeneu Menadas J, Amiguet Comins M, González D’gregorio J, Serrano Alcalá A, Montagud V, Lopez-Vilella R, Valero Picher E, Garcia Blas S, Bodí Peris V, De La Espriella Juan R, Lupon J, Navarro Perez J, Górriz Teruel J, Sanchis Fores J, Chorro Gascó F, Comin-Colet J, Bayes Genis A, Myocardial-IRON Investigators. Journal of the American Heart Association. 2020 Feb 18;9(4):e014254. doi: 10.1161/JAHA.119.014254. PMID: 32067585

Oxygen therapy and palliative care in patients with heart failure. Response. Garcia-Pinilla JM, Diez-Villanueva P, Crespo Leiro MG, Bonanad Lozano C. Revista Espanola de Cardiologia. 2020 Jul;73(7):599. doi: 10.1016/j.rec.2020.01.024. PMID: 32376230

Prognostic impact of anemia according to frailty status in elderly patients with acute coronary syndromes. Ariza-Sole A, Lorente V, Formiga F, Lopez-Palop R, Sanchis Fores J, Marin F, Vidan M, Martinez-Selles M, Sanchez-Salado J, Garay A, Guerrero C, Bueno H, Alegre O, Abu-Assi E, Cequier A, Bonanad Lozano C, LONGEVO-SCA registry investigators. Journal of Cardiovascular Medicine. 2020 Jan;21(1):27-33. doi: 10.2459/JCM.0000000000000884. PMID: 31652170

Randomized Comparison of Exercise Intervention Versus Usual Care in Older Adult Patients with Frailty After Acute Myocardial Infarction. Sanchis J, Sastre C, Ruescas A, Ruiz V, Valero E, Bonanad C, Garcia-Blas S, Fernandez-Cisnal A, Gonzalez J, Minana G, Nunez J. American Journal of Medicine. 2020 Oct 24;S0002-9343(20)30904-9. doi: 10.1016/j.amjmed.2020.09.019. PMID: 33228950

Relation of Low Lymphocyte Count to Frailty and its 11) Usefulness as a Prognostic Biomarker in Patients >65 Years of Age With Acute Coronary Syndrome. Nuñez Villota J, Sastre Arbona C, D’ascoli G, Ruiz Ros V, Bonanad Lozano C, Miñana Escriva G, Valero Picher E, Garcia Blas S, Mollar Fernandez A, Villaescusa Capilla M, Arantzazu Ruescas-Nicolau M, Nuñez Benito E, Formiga F, Chorro Gascó F, Sanchis Fores J. American Journal of Cardiology. 2020 Apr 1;125(7):1033-1038. doi: 10.1016/j.amjcard.2020.01.006. PMID: 31959430

Role of PCSK9 in the course of ejection fraction change after ST-segment elevation myocardial infarction: a pilot study. Miñana Escriva G, Nuñez Villota J, Bayes Genis A, Revuelta-Lopez E, Rios Navarro C, Nuñez Benito E, Chorro Gascó F, Lopez Lereu M, Monmeneu Menadas J, Lupon J, Sanchis Fores J, Bodí Peris V. Esc Heart Failure. 2020 Feb;7(1):117-122. doi: 10.1002/ehf2.12533. PMID: 31903686

Sex-differential effect of frailty on long-termmortality in elderly patients after an acute coronary síndrome. Nuñez Villota J, Palau P, Sastre Arbona C, D’ascoli G, Ruiz Ros V, Bonanad Lozano C, Miñana Escriva G, Nunez E, Sanchis Fores J. International Journal of Cardiology. 2020 Mar 1;302:30-33. doi: 10.1016/j.ijcard.2019.12.068. PMID: 31924393

Similar Clinical Course and Significance of Circulating Innate and Adaptive Immune Cell Counts in STEMI and COVID-19. de Dios E, Rios-Navarro C, Perez-Sole N, Gavara J, Marcos-Garces V, Rodríguez E, Carratalá A, Forner MJ, Navarro J, Blasco ML, Bondia E, Signes-Costa J, Vila JM, Forteza MJ, Chorro 1MJ, Bodi V. Journal of Clinical Medicine. 2020 Oct 28;9(11):E3484. doi: 10.3390/jcm9113484. PMID: 33126723

sST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction. De La Espriella Juan R, Bayes-Genis A, Revuelta E, Miñana Escriva G, Santas Olmeda E, Llacer P, Garcia Blas S, Fernández Cisnal A, Bonanad Lozano C, Ventura S, Sanchez R, Bodí Peris V, Cordero A, Facila De La Esperanza R, Mollar Fernandez A, Sanchis Fores J, Improve-Hf Investigators, Nuñez Villota J. Journal Of Cardiac Failure. 2020 Oct 8;S1071-9164(20)31473-1. doi: 10.1016/j.cardfail.2020.10.002. PMID: 33038531

The Effect of Age on Mortality in Patients With COVID-19: A Meta-Analysis With 611,583 Subjects. Bonanad Lozano C, Garcia Blas S, Tarazona-Santabalbina F, Sanchis Fores J, Bertomeu-Gonzalez V, Facila De La Esperanza R, Ariza A, Nuñez Villota J, Cordero A. Journal of the American Medical Directors Association. 2020 Jul;21(7):915-918. doi: 10.1016/j.jamda.2020.05.045. PMID: 32674819

Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease: A Large Retrospective Registry. Marcos Garcés V, Gavara Doñate J, Monmeneu Menadas J, Lopez-Lereu M, Bosch M, Merlos P, Pérez Solé N, Rios Navarro C, De Dios Lluch E, Bonanad Lozano C, Racugno P, Bellver Navarro A, Ventura Perez B, Aguilar Botella J, Ventura Haro S, Mainar Latorre L, Canoves Femenia J, Pellicer Bañuls M, Moratal Perez D, Miñana Escriva G, Nuñez Villota J, Chorro Gascó F, Bodí Peris V- Jacc-Cardiovascular Imaging. 2020 Aug;13(8):1674-1686. doi: 10.1016/j.jcmg.2020.02.027. PMID: 32682717

Anatomy, immunohistochemistry, and numerical distribution of human splenic microvessels. Almenar S, Rios-Navarro C, Ortega M, Molina P, Ferrandez-Izquierdo A, Ruiz-Sauri A. Annals Of Anatomy. 2019 Jul;224:161-171. doi: 10.1016/j.aanat.2019.05.004. PMID: 31121286

Changes in the spatial distribution of the Purkinje network after acute myocardial infarction in the pig. Garcia-Bustos V, Sebastian R, Izquierdo M, Rios-Navarro C, Bodí V, Chorro FJ, Ruiz-Sauri A. PLoS One. 2019 Feb 11;14(2):e0212096. doi: 10.1371/journal.pone.0212096. PMID: 30742681

Combining Disability and Frailty in an Integrated Scale for Prognostic Assessment After Acute Coronary Syndrome. Sanchis J, Ruiz V, Ariza-Solé A, Ruescas A, Bonanad C, Núñez J. Revista Espanola de Cardiologia. 2019 May;72(5):430-431. doi: 10.1016/j.rec.2018.04.020. PMID: 29857973

Comments on the 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension. SEC Working Group for the 2018 ESC ESH Guidelines on Arterial Hypertension; Expert Reviewers for the 2018 ESC ESH Guidelines on Arterial Hypertension; SEC Guidelines Committee. Revista Espanola de Cardiologia. 2019 Feb;72(2):104-108. doi: 10.1016/j.rec.2018.12.001. PMID: 30704721

Comorbidity assessment for mortality risk stratification in elderly patients with acute coronary síndrome. Sanchis J, Soler M, Núñez J, Ruiz V, Bonanad C, Formiga F, Valero E, Martínez-Sellés M, Marín F, Ruescas A, García-Blas S, Miñana G, Abu-Assi E, Bueno H, Ariza-Solé A. European Journal of Internal Medicine. 2019 Apr;62:48-53. doi: 10.1016/j.ejim.2019.01.018. PMID: 30711360

Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. Ray KK, Colhoun HM, Szarek M, Baccara-Dinet M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Lopes RD, Moryusef A, Murin J, Pordy R, Ristic AD, Roe MT, Tuñón J, White HD, Zeiher AM, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Lancet Diabetes & Endocrinology. 2019 Aug;7(8):618-628. doi: 10.1016/S2213-8587(19)30158-5. PMID: 31272931

Euphorbia honey and garlic: Biological activity and burn wound recovery. Ait Abderrahim L, Taïbi K, Ait Abderrahim N, Boussaid M, Rios-Navarro C, Ruiz-Saurí A. BURNS. 2019 Nov;45(7):1695-1706. doi: 10.1016/j.burns.2019.05.002. PMID: 31167717

Functional tricuspid regurgitation and recurrent admissions in patients with acute heart failure. De la Espriella R, Santas E, Chorro FJ, Miñana G, Soler M, Bodí V, Valero E, Núñez E, Bayés-Genis A, Lupón J, Sanchis J, Núñez J. International Journal of Cardiology. 2019 Sep 15;291:83-88. doi: 10.1016/j.ijcard.2019.03.051. PMID: 30955879

Glia to neuron ratio in the posterior aspect of the human spinal cord at thoracic segments relevant to spinal cord stimulation. Ruiz Sauri A, Orduña Valls J, Blasco-Serra A, Tornero Tornero C, Cedeno D, Bejarano-Quisoboni D, Valverde-Navarro A, Benyamin R, Vallejo R. Journal of Anatomy. 2019 Nov;235(5):997-1006. doi: 10.1111/joa.13061. PMID: 31347695

Growth differentiation factor 15 and geriatric conditions in acute coronary síndrome. Sanchis J, Ruiz V, Bonanad C, Sastre C, Ruescas A, Díaz M, Rodríguez E, Valero E, García-Blas S, Carratalá A, Núñez E, Núñez J. International Journal of Cardiology. 2019 Sep 1;290:15-20. doi: 10.1016/j.ijcard.2019.05.034. PMID: 31130280

Histological and morphometric study of the components of the sinus and atrioventricular nodes in horses and dogs. Gómez-Torres FA, Ballesteros-Acuña LE, Ruíz-Sauri A. Research In Veterinary Science. 2019 Oct;126:22-28. doi: 10.1016/j.rvsc.2019.08.001. PMID: 31421508

Inspiratory Muscle Training and Functional Electrical Stimulation for Treatment of Heart Failure With Preserved Ejection Fraction: The TRAINING-HF Trial. Palau P, Domínguez E, López L, Ramón JM, Heredia R, González J, Santas E, Bodí V, Miñana G, Valero E, Mollar A, Bertomeu González V, Chorro FJ, Sanchis J, Lupón J, Bayés-Genís A, Núñez J. Revista Espanola de Cardiologia. 2019 Apr;72(4):288-297. doi: 10.1016/j.rec.2018.01.010. PMID: 29551699

International Normalized Ratio and Mortality Risk in Acute Heart Failure and Nonvalvular Atrial Fibrillation Patients Receiving Vitamin K Antagonists. Santas E, Miñana G, Gummel J, Farcasan R, Payá A, Heredia R, Bodí V, Mollar A, Bertomeu-González V, Chorro FJ, Sanchis J, Lupón J, Bayés Genís A, Núñez J. Revista Espanola de Cardiologia. 2019 Aug;72(8):616-624. doi: 10.1016/j.rec.2018.07.010. PMID: 30201288

Invasive strategy in elderly patients with acute coronary syndrome in 2018: close to the truth?. García-Blas S, Bonanad C, Sanchis J. Journal of Geriatric Cardiology. 2019 Feb;16(2):114-120. doi: 10.11909/j.issn.1671-5411.2019.02.004. PMID: 30923542

Magnetic resonance microscopy and correlative histopathology of the infarcted heart. Perez-Terol I, Rios-Navarro C, de Dios E, Morales JM, Gavara J, Perez-Sole N, Diaz A, Minana G, Segura-Sabater R, Bonanad C, Bayés-Genis A, Husser O, Monmeneu JV, Lopez-Lereu MP, Nunez J, Chorro FJ, Ruiz-Sauri A, Bodi V, Monleon D. Scientific Reports. 2019 Dec 27;9(1):20017. doi: 10.1038/s41598-019-56436-5. PMID: 31882712

Mangiferin nanoemulsions in treatment of inflammatory disorders and skin regeneration. Pleguezuelos-Villa M, Nácher A, Hernández MJ, Ofelia Vila Buso MA, Ruiz Sauri A, Díez-Sales O. International Journal of Pharmaceutics. 2019 Jun 10;564:299-307. doi: 10.1016/j.ijpharm.2019.04.056. PMID: 31015007

Microvascular Obstruction in ST-Segment Elevation Myocardial Infarction: Looking Back to Move Forward. Focus on CMR. Rios-Navarro C, Marcos-Garces V, Bayes-Genis A, Husser O, Nuñez J, Bodi V. Journal of Clinical Medicine. 2019 Oct 28;8(11):1805. doi: 10.3390/jcm8111805. PMID: 31661823

Prognostic Value of Initial LeftVentricular Remodeling in PatientsWith Reperfused STEMI. Rodriguez-Palomares JF, Gavara J, Ferreira-González I, Valente F, Rios C, Rodríguez-García J, Bonanad C, García Del Blanco B, Miñana G, Mutuberria M, Nuñez J, Barrabés J, Evangelista A, Bodí V, García-Dorado D. JACC-Cardiovascular Imaging. 2019 Dec;12(12):2445-2456. doi: 10.1016/j.jcmg.2019.02.025. PMID: 31202752

Recommendations of the Geriatric Cardiology Section of the Spanish Society of Cardiology for the Assessment of Frailty in Elderly Patients With Heart Disease. Díez-Villanueva P, Arizá-Solé A, Vidán MT, Bonanad C, Formiga F, Sanchis J, Martín-Sánchez FJ, Ruiz Ros V, Sanmartín Fernández M, Bueno H, Martínez-Sellés M. Revista Espanola de Cardiologia. 2019 Jan;72(1):63-71. doi: 10.1016/j.rec.2018.06.035. PMID: 30269913

Strain by Feature Tracking: A Short Summary of the Journey of CMR in STEMI. Bodi V. JACC-Cardiovascular Imaging. 2019 Jul;12(7 Pt 1):1199-1201. doi: 10.1016/j.jcmg.2018.08.009. PMID: 30219409

Unusual Hydatid Cyst-Like Images Caused by Staphylococcus Lugdunensis Infective Endocarditis. Marcos-Garcés V, Santas E, Pellicer M, Ruiz-Granell R, Chorro FJ. Heart, Lung & Circulation. 2019 Feb;28(2):e16-e18. doi: 10.1016/j.hlc.2018.07.008. PMID: 30126792

Proyectos
Referencia: PI20/00637
Título: Resolución de la obstrucción microvascular tras un infartodemiocardio: evaluación de las consecuencias estructurales y clínicas y búsqueda de nuevas opciones terapéuticas
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Vicent Bodí Peris, Clara Bonanad Lozano
Duración: 2021 – 2023
Presupuesto: 129.470 €

Referencia: GV/2018/116
Título: Estudio multidisciplinar de la dinámica, mecanismos básicos, diagnóstico y exploración de nuevas oportunidades terapéuticas en la obstrucción microvascular tras infarto agudo de miocardio
Entidad Financiadora: Conselleria de Educación Cultura y Deporte
Investigador principal: Clara Bonanad Lozano
Duración: 2018 – 2019
Presupuesto: 15.000 €

Referencia: PI17/01836
Título: Estudio multidisciplinar de la obstrucción microvascular y su reparación tras un infarto agudo demiocardio: de la arteria coronaria a la microcirculación. Foco en el factor VEGF-A165b
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Vicente Bodí Peris
Duración: 2018 – 2020
Presupuesto: 99.220 €

Referencia: PIE15/00013
Título: A multidisciplinary Project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Vicente Bodí Peris
Duración: 2016 – 2019
Presupuesto: 589.050 €

+ Información
Comments on the 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension. SEC Working Group for the 2018 ESC ESH Guidelines on Arterial Hypertension; Expert Reviewers for the 2018 ESC ESH Guidelines on Arterial Hypertension; SEC Guidelines Committee. Revista Espanola de Cardiologia. 2019 Feb;72(2):104-108. doi: 10.1016/j.rec.2018.12.001. PMID: 30704721

Título: Estudio de la deformidad del tejido cardiaco (strain) tras un infarto de miocardio con elevación del segmento ST mediante la técnica de resonancia magnética tissue tracking: dinámica, implicación estructural y valor pronóstico
Doctorando: Gavara Doñate, Josep
Director: Monmeneu Menadas José Vicente; Bodí Peris Vicente
Fecha: 19/06/2020
Universidad: Universitat de València

Título: Comparación de las diferentes técnicas de cementación de la bandeja tibial en las prótesis de rodilla
Doctorando: Rodríguez Collell, Juan Ramón
Director: Valverde Navarro, Alfonso A; Mifsut Miedes, Damián; Ruiz Saurí, Amparo
Fecha: 11/09/2020
Universidad: Universitat de València