Dra. Cecilia Martínez Costa

Investigador Principal
Grupo de Investigación de Nutrición pediátrica

Presentación

La Dra. Martínez es Catedrática de Pediatría de la Universidad de Valencia y Jefa del Servicio de Pediatría del Hospital Clínico Universitario de Valencia.

Investigadora principal del Grupo de Investigación en Nutrición Pediátrica de INCLIVA integrado por pediatras, investigadores básicos, enfermeros y nutricionistas. Ha participado en numerosos proyectos de investigación traslacional todos ellos en colaboración con áreas clínicas y básicas. Cuenta con cuatro sexenios de investigación reconocidos por ANECA.

Co-chair del Topic Advisory Group for Nutrition de WHO (World Health Organization) que ha desarrollado la clasificación y terminología de los trastornos nutricionales para la versión 11 de ICD (International Classification of Diseases). Miembro del WHO Guideline Developing Group for Preventing obesity in children and adolescents through appropiate infant and child feeding practices, 2015, siendo la única representante española.

Miembro numerario de los grupos de trabajo de nutrición de las sociedades científicas: SEGHNP (Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica) y SENPE (Sociedad Española de Nutrición Enteral y parenteral) que elaboran las guías de nutrición enteral y parenteral pediátricas. Miembro de ESPGHAN (European Society for Pediatric Gastroenterology, Hepatology and Nutrition).

Investigador
Principal
Dra. Cecilia Martínez Costa

cecilia.martinez@uv.es/cmcosta@uv.es

Publicaciones
Breastfeeding practices influence the breast milk microbiota depending on pre-gestational maternal bmi and weight gain over pregnancy. Cortes-Macias E, Selma-Royo M, Martinez-Costa C, Collado MC. Nutrients. 2021 Apr 30;13(5):1518. doi: 10.3390/nu13051518. PMID: 33946343

Case Report: Primary Peritonitis as the Onset of Pediatric Menetrier’s Disease. Barres-Fernandez A, Piolatti-Luna A, Breton-Martinez J, Crehua-Gaudiza E, Quinones-Torrelo C, Moscardo-Navarro A, Fuertes-Latasa C, Martinez-Costa C. Frontiers in Pediatrics. 2021 Jan 13;8:589853. doi: 10.3389/fped.2020.589853. PMID: 33520889

Evaluation of a rapid antigen detection test (Panbio (TM) COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department. Carbonell-Sahuquillo S, Lazaro-Carreno M, Camacho J, Barres-Fernandez A, Albert E, Torres I, Breton-Martinez J, Martinez-Costa C, Navarro D. Journal of Medical Virology. 2021 Jul 21. doi: 10.1002/jmv.27220. PMID: 34289136

Human milk oligosaccharides, infant growth, and adiposity over the first 4 months of lactation. Binia A, Lavalle L, Chen C, Austin S, Agosti M, Al-Jashi I, Pereira A, Costeira M, Silva M, Marchini G, Martinez-Costa C, Stiris T, Stoicescu S, Vanpee M, Rakza T, Billeaud C, Picaud J, Domellof M, Adams R, Castaneda-Gutierrez E, Sprenger N. Pediatric Research. 2021 Jan 14. doi: 10.1038/s41390-020-01328-y. PMID: 33446921

Initial viral load and decay kinetics of SARS-CoV-2 lineage B.1.1.7 in the upper respiratory tract of adults and children. Costa R, Bueno F, Gimenez E, Bracho A, Albert E, Carretero D, de Michelena P, Martinez-Costa C, Gonzalez-Candelas F, Navarro D. Journal of Infection. 2021 Aug 11;S0163-4453(21)00398-4. doi: 10.1016/j.jinf.2021.08.015. PMID: 34390756

Levels of predominant intestinal microorganisms in 1 month-old full-term babies and weight gain during the first year of life. Gonzalez S, Selma-Royo M, Arboleya S, Martinez-Costa C, Solis G, Suarez M, Fernandez N, de los Reyes-Gavilan C, Diaz-Coto S, Martinez-Camblor P, Collado M, Gueimonde M. Nutrients. 2021 Jul 14;13(7):2412. doi: 10.3390/nu13072412. PMID: 34371922

Maternal diet during pregnancy and intestinal markers are associated with early gut microbiota. Selma-Royo M, García Mantrana I, Calatayud M, Parra-Llorca A, Martinez Costa C, Collado M. European Journal Of Nutrition. 2021 Apr;60(3):1429-1442. doi: 10.1007/s00394-020-02337-7. PMID: 32728880

Maternal Diet Shapes the Breast Milk Microbiota Composition and Diversity: Impact of Mode of Delivery and Antibiotic Exposure. Cortes-Macias E, Selma-Royo M, Garcia-Mantrana I, Calatayud M, Gonzalez S, Martinez-Costa C, Collado M. Journal of Nutrition. 2021 Feb 1;151(2):330-340. doi: 10.1093/jn/nxaa310. PMID: 33188413

Non-wild-type cryptococcosis in a child with multivisceral organ transplant who owned bird pets. Breton-Martinez J, Alcolea A, Quintero-Garcia D, Mendez-Echevarria A, Ramos E, Bueno F, Colomina J, Mari-Lopez J, Crehua-Gaudiza E, Garcia-Rodriguez J, Martinez-Costa C. Transplant Infectious Disease. 2021 Jan 1;e13558. doi: 10.1111/tid.13558. PMID: 33386674

SARS-CoV-2 RNA and antibody detection in breast milk from a prospective multicentre study in Spain. Bauerl C, Randazzo W, Sanchez G, Selma-Royo M, Garcia-Verdevio E, Martinez L, Parra-Llorca A, Lerin C, Fumado V, Crovetto F, Crispi F, Perez-Cano F, Rodriguez G, Ruiz-Redondo G, Campoy C, Martinez-Costa C, Collado M, MilkCORONA study team. Archives of Disease in Childhood. Fetal and Neonatal Edition. 2021 Aug 20;fetalneonatal-2021-322463. doi: 10.1136/archdischild-2021-322463. PMID: 34417223

Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults. Costa R, Bueno F, Albert E, Torres I, Carbonell-Sahuquillo S, Barres-Fernandez A, Sanchez D, Padron C, Colomina J, Lazaro Carreno M, Breton-Martinez J, Martinez-Costa C, Navarro D. Clinical Microbiology and Infection. 2021 Aug 9;S1198-743X(21)00438-9. doi: 10.1016/j.cmi.2021.08.001. PMID: 34384874

Usefulness of complementary test in the study of patients with chronic abdominal pain. Jimenez Candel M, Salvador Pinto T, Garcia Peris M, Crehua Gaudiza E, Jovani Casano C, Moreno Ruiz M, Hernandez Berto T, Largo Blanco E, Martinez Costa C. Anales de Pediatria. 2021 Jul;95(1):26-32. doi: 10.1016/j.anpedi.2020.04.030. PMID: 32690403

Diagnosis of celiac disease in clinical practice: present and future. Crehua-Gaudiza E, Barres Fernandez A, Jovani Casano C, Latorre Tejerina M, Largo Blanco E, Moreno Ruiz M, Berghezan Suarez A, Garcia-Peris M, Gil Piquer R, Coret Sinisterra A, Martinez-Barona S, Salido-Capilla C, Requena Fernandez M, Arcos-Machancoses J, Martinez-Costa C. Anales de Pediatria. 2020 Sep 2;S1695-4033(20)30258-7. doi: 10.1016/j.anpedi.2020.07.008. PMID: 32891578

Distinct maternal microbiota clusters are associated with diet during pregnancy: impact on neonatal microbiota and infant growth during the first 18 months of life. García Mantrana I, Selma-Royo M, Gonzalez S, Parra-Llorca A, Martinez Costa C, Collado M. Gut Microbes. 2020 Jul 3;11(4):962-978. doi: 10.1080/19490976.2020.1730294. PMID: 32167021

Home and Ambulatory Artificial Nutrition (NADYA) Group Report. Home parenteral nutrition in Spain, 2018. Wanden-Berghe Lozano C, Cuerda Compes C, Maiz Jimenez M, Pereira Cunill J, Ramos Boluda E, Gomez Candela C, Virgili Casas M, Burgos Pelaez R, de Luis Roman D, Penacho Lazaro M, Sanchez Martos E, Martinez Faedo C, Diaz Guardiola P, Alvarez Hernandez J, Zugasti Murillo A, Campos Martin C, Sanz Paris A, Martin Fontalba M, Lobo-Tamer G, Matia Martin M, Carabana Perez F, Martin Folgueras T, Martin Palmero M, Luengo Perez L, Sanchez-Vilar Burdiel O, MARTINEZ COSTA C, Tejera C, Martinez Ramirez M, Garcia Delgado Y, Ponce Gonzalez M, Mauri Roca S, Garcia Zafra M, German Diaz M, Romero V, Molina Baeza B, Gonzalo Marin M, Irles Rocamora J, Sanchez Sanchez R, Apezetxea Celaya A, Joaquin Ortiz C, Suarez Llanos J, Pintor de la Maza B, Leyes Garcia P, Gil Martinez M, Carrera Santaliestra M. Nutricion Hospitalaria. 2020 Apr 16;37(2):403-407. doi: 10.20960/nh.02976. PMID: 32124618

Maternal Microbiota, Cortisol Concentration, and Post-Partum Weight Recovery are Dependent on Mode of Delivery. Selma-Royo M, García Mantrana I, Calatayud M, Parra-Llorca A, Martinez Costa C, Collado M. Nutrients. 2020 Jun 15;12(6):1779. doi: 10.3390/nu12061779. PMID: 32549282

Multicentre longitudinal study of the nutritional status and swallowing difficulties in children with severe neurological diseases. Crehua-Gaudiza E, Garcia-Peris M, Jovani-Casano C, Moreno-Ruiz M, Martinez-Costa C. Revista de Neurologia. 2020 Sep 16;71(6):213-220. doi: 10.33588/rn.7106.2020032. PMID: 32895904

Multicomponent Exercise Training Combined with Nutritional Counselling Improves Physical Function, Biochemical and Anthropometric Profiles in Obese Children: A Pilot Study. Cordellat Marzal A, Padilla Lopez B, Grattarola P, Garcia Lucerga C, Crehuá Gaudiza E, Nuñez Gomez F, Martinez Costa C, Blasco Lafarga M. Nutrients. 2020 Sep 6;12(9):2723. doi: 10.3390/nu12092723. PMID: 32899955

Perinatal environment shapes microbiota colonization and infant growth: impact on host response and intestinal function. Selma-Royo M, Calatayud Arroyo M, Garcia-Mantrana I, Parra-Llorca A, Escuriet R, Martinez-Costa C, Collado M. Microbiome. 2020 Nov 23;8(1):167. doi: 10.1186/s40168-020-00940-8. PMID: 33228771

Sjogren-Larsson syndrome in Spain: Description of three new cases. Villar Vera C, Cuesta Peredo A, Monfort Belenguer L, Abellán Sánchez M, Martinez Costa C. Anales de Pediatría. 2020 Sep 17;S1695-4033(20)30273-3. doi: 10.1016/j.anpedi.2020.07.020. PMID: 32952065

Association of Maternal Secretor Status and Human Milk Oligosaccharides With Milk Microbiota: An Observational Pilot Study. Cabrera-Rubio R, Kunz C, Rudloff S, García-Mantrana I, Crehuá-Gaudiza E, Martínez-Costa C, Collado MC. Journal of Pediatric Gastroenterology and Nutrition. 2019 Feb; 68(2): 256-263. doi: 10.1097/MPG.0000000000002216. PMID: 30540710

Effect of a surveillance system for decreasing neonatal nosocomial infections. Estañ-Capell J, Alarcón-Torres B, Bermúdez JD, Martínez-Rodríguez L, Martínez-Costa C. Early Human Development. 2019 Apr;131:36-40. doi: 10.1016/j.earlhumdev.2019.02.006. PMID: 30825743

Impact of maternal characteristics on human milk oligosaccharide composition over the first 4 months of lactation in a cohort of healthy European mothers. Samuel TM, Binia A, de Castro CA, Thakkar SK, Billeaud C, Agosti M, Al-Jashi I, Costeira MJ, Marchini G, Martínez-Costa C, Picaud JC, Stiris T, Stoicescu SM, Vanpeé M, Domellöf M, Austin S, Sprenger N. Scientific Reports. 2019 Aug 13;9(1):11767. doi: 10.1038/s41598-019-48337-4. PMID: 31409852

MAMI: a birth cohort focused on maternal-infant microbiota during early life. García-Mantrana I, Alcántara C, Selma-Royo M, Boix-Amorós A, Dzidic M, Gimeno-Alcañiz J, Úbeda-Sansano I, Sorribes-Monrabal I, Escuriet R, Gil-Raga F, Parra-Llorca A, Martínez-Costa C, Collado MC; MAMI team. BMC Pediatrics. 2019 May 3;19(1):140. doi: 10.1186/s12887-019-1502-y. PMID: 31053102

Nutritional Outcome in Home Gastrostomy-Fed Children with Chronic Diseases. Martínez-Costa C, Calderón C, Gómez-López L, Borraz S, Crehuá-Gaudiza E, Pedrón-Giner C. Nutrients. 2019 Apr 26;11(5):956. doi: 10.3390/nu11050956. PMID: 31035481

Subclinical Mastitis in a European Multicenter Cohort: Prevalence, Impact on Human Milk (HM) Composition, and Association With Infant HM Intake and Growth. Samuel TM, De Castro CA, Dubascoux S, Affolter M, Giuffrida F, Billeaud C, Picaud JC, Agosti M, Al-Jashi I, Pereira AB, Costeira MJ, Silva MG, Marchini G, Rakza T, Haaland K, Stiris T, Stoicescu SM,Martínez-Costa C, Vanpee M, Domellöf M, Euridice CG, Thakkar SK, Silva-Zolezzi I. Nutrients. 2019 Dec 30;12(1):105. doi: 10.3390/nu12010105. PMID: 31905959

The Microbiota and Malnutrition: Impact of Nutritional Status During Early Life. Gómez-Gallego C, García-Mantrana I, Martínez-Costa C, Salminen S, Isolauri E, Collado MC. Annual Review of Nutrition. 2019 Aug 21;39:267-290. doi: 10.1146/annurev-nutr-082117-051716. PMID: 31433738

+ Información
Título: Antígenos histo-sanguíneos e infección por rotavirus
Doctorando: Pérez Ortín, Raúl
Director: Buesa Gómez, Francisco Javier
Fecha: 15/01/2020
Universidad: Universitat de València

Título: Aplicación de la termografía infrarroja en pediatría: análisis de las alteraciones de la microcirculación cutánea
Doctorando: Benavent Casanova, Olga
Director: Núñez Gómez, Francisco; Cibrián Ortíz De Anda, Rosa; Salvador Palmer, María Rosario
Fecha: 23/07/2020
Universidad: Universitat de València

Título: Aproximaciones moleculares al estudio de las interacciones de rotavirus y norovirus con el huésped
Doctorando: Vila Vicent, Susana
Director: Rodríguez Díaz, Jesús; Buesa Gómez, Francisco Javier
Fecha: 05/11/2020
Universidad: Universitat de València

Título: Efecto de la intervención nutricional en escolares y adolescentes con obesidad con y sin resistencia a la insulina
Doctorando: Grattarola, Ana Paula
Director: Núñez Gómez, Francisco; Martínez Costa, Cecilia
Fecha: 11/01/2021
Universidad: Universitat de València