Grupo de Investigación en Salud de la Mujer

Área de Medicina Reproductiva

El grupo se posiciona en el campo del envejecimiento saludable, especialmente en lo relacionado a las mujeres, con especial interés por la fragilidad, donde ha colaborado en el apoyo de INCLIVA en el proyecto ADVANTAGE. Hemos colaborado para posicionar el sitio de referencia de la Comunitat Valenciana dentro de EIPAHA, el partenariado de la Comisión Europea. Además, hemos participado en la postulación a diferentes proyectos europeos con grupos de diferentes países europeos, incluida una postulación a las becas Maire Curie
Coordinador
Dr. Antonio Cano Sánchez
antonio.cano@uv.es/acano@uv.es

INVESTIGADORES
R4 Senior

Antonio Cano Sánchez    
Juan José Tarín Folgado

R3 Consolidado
R2 Novel / Emergente

Ana Martínez Aspas
Celia Bauset Castelló
Ester Ortiz Murillo
Gemma Arribas Ferriol
Irene Zolfaroli

R1 Predoctoral
STAFF
Colaborador/a

Aitana Monllor Tormos
Laura Carbonell López
Rocío Belda Montesinos

Enfermero/a

Alicia García Vigara

Técnico/a
Apoyo
Publicaciones
Non-use of information and communication technology as a predictor of frailty in postmenopausal midlife and older women. Garcia-Vigara A, Cano A, Fernandez-Garrido J, Carbonell-Asins J, Tarin J, Sanchez-Sanchez M. Maturitas. 2022 Feb;156:60-64. doi: 10.1016/j.maturitas.2021.05.010. PMID: 34275701

A reassessment of the therapeutic potential of a dopamine receptor 2 Agonist (D2-AG) in endometriosis by comparison against a standardized antiangiogenic treatment. Tejada M, Santos-Llamas A, Fernandez-Ramirez M, Tarin J, Cano A, Gomez R. Biomedicines. 2021 Mar 8;9(3):269. doi: 10.3390/biomedicines9030269. PMID: 33800198

Bazedoxifene increases the proliferation of human arterial endothelial cells but does not affect the expression of cyclins A, B, and D1 and of p27(Kip1). Dudenko D, Gomez R, Garcia-Perez M, Tarin J, Cano A. Gynecological Endocrinology. 2021 Mar;37(3):269-272. doi: 10.1080/09513590.2021.1876653. PMID: 33480311

Body weight and fat mass across the menopausal transition: hormonal modulators. Moccia P, Belda-Montesinos R, Monllor-Tormos A, Chedraui P, Cano A. Gynecological Endocrinology. 2021 Dec 13;1-6. doi: 10.1080/09513590.2021.2004395. PMID: 34898344

Comparison of IOTA three-step strategy and logistic regression model LR2 for discriminating between benign and malignant adnexal masses. Hidalgo JJ, Llueca A, Zolfaroli I, Veiga N, Ortiz E, Alcazar JL. Medical Ultrasonography. 2021 May 20;23(2):168-175. doi: 10.11152/mu-2732. PMID: 33626112

Female genital mutilation consequences and healthcare received among migrant women: a phenomenological qualitative study. Gonzalez-Timoneda A, Gonzalez-Timoneda M, Cano Sanchez A, Ruiz Ros V. International Journal of Environmental Research and Public Health. 2021 Jul 5;18(13):7195. doi: 10.3390/ijerph18137195. PMID: 34281134

Global consensus recommendations on menopause in the workplace: a European Menopause and Andropause Society (EMAS) position statement. Rees M, Bitzer J, Cano A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Geukes M, Godfrey A, Goulis DG, Griffiths A, Hardy C, Hickey M, Hirschberg AL, Hunter M, Kiesel L, Jack G, Lopes P, Mishra G, Oosterhof H, Pines A, Riach K, Shufelt C, van Trotsenburg M, Weiss R, Lambrinoudaki I. Maturitas. 2021 Sep;151:55-62. doi: 10.1016/j.maturitas.2021.06.006. PMID: 34274202

Management of urinary incontinence in postmenopausal women: An EMAS clinical guide. Russo E, Caretto M, Giannini A, Bitzer J, Cano Sanchez A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis D, Kiesel L, Lambrinoudaki I, Hirschberg A, Lopes P, Pines A, Rees M, van Trotsenburg M, Simoncini T. Maturitas. 10.1016/j.maturitas.2020.09.005. doi: 10.1016/j.maturitas.2020.09.005. PMID: 33008675

Ovarian steroids and cancer: news on the breast, questions on the reproductive tract. Hidalgo-Mora J, Tarin J, Cano A. Gynecological Endocrinology. 2021 May;37(5):383-384. doi: 10.1080/09513590.2021.1904871. PMID: 33825589

Positive association of high-density lipoprotein cholesterol with lumbar and femoral neck bone mineral density in postmenopausal women. Zolfaroli I, Ortiz E, Garcia-Perez M, Hidalgo-Mora J, Tarin J, Cano A. Maturitas. 2021 May;147:41-46. doi: 10.1016/j.maturitas.2021.03.001. PMID: 33832646

Randomized controlled trial for promotion of healthy eating in older adults by increasing consumption of plant-based foods: effect on inflammatory biomarkers. Nilsson A, Cano A, Bergens O, Kadi F. Nutrients. 2021 Oct 24;13(11):3753. doi: 10.3390/nu13113753. PMID: 34836009

Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence. Castelo-Branco C, Gambacciani M, Cano A, Minkin M, Rachon D, Ruan X, Beer A, Schnitker J, Henneicke-von Zepelin H, Pickartz S. Climacteric. 2021 Apr;24(2):109-119. doi: 10.1080/13697137.2020.1820477. PMID: 33021111

Serum microRNAs in osteoporotic fracture and osteoarthritis: a genetic and functional study. Pertusa C, Tarin JJ, Cano A, Garcia-Perez MA, Mifsut D. Scientific Reports. 2021 Sep 29;11(1):19372. doi: 10.1038/s41598-021-98789-w. PMID: 34588560

Ten-year assessment of a cancer fast-track programme to connect primary care with oncology: reducing time from initial symptoms to diagnosis and treatment initiation. Martinez MT, Monton-Bueno J, Simon S, Ortega B, Moragon S, Rosello S, Insa A, Navarro J, Sanmartin A, Julve A, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner MJ, Cano A, Silvestre A, Teruel A, Lluch A, Cervantes A, Chirivella Gonzalez I. ESMO open. 2021 May 11;6(3):100148. doi: 10.1016/j.esmoop.2021.100148. PMID: 33989988

The RANKL/RANK system in female reproductive organ tumors: a preclinical and clinical overview. Monzo-Miralles A, Martin-Gonzalez V, Smith-Ballester S, Iglesias-Miguel V, Cano A. Advances in Clinical and Experimental Medicine. 2021 Sep;30(9):879-883. doi: 10.17219/acem/140422. PMID: 34435475

Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide. Hirschberg AL, Bitzer J, Cano A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis DG, Kiesel L, Lopes P, Pines A, van Trotsenburg M, Lambrinoudaki I, Rees M. Maturitas. 2021 Jun;148:55-61. doi: 10.1016/j.maturitas.2021.04.005. PMID: 33896654

Variants translating reduced expression of the beta estrogen receptor gene were associated with increased carotid intima media thickness: A cross-sectional study in late postmenopausal women. Cano-Marquina AJ, Garcia-Perez MA, Tarin JJ, Maceira AM, Cosin-Sales J, Cano A. Medicine. 2021 Jun 11;100(23):e26216. doi: 10.1097/MD.0000000000026216. PMID: 34115005

A predictive model for women’s assisted fecundity before starting the first IVF/ICSI treatment cycle (vol 36, pg 235, 2019). Tarin Folgado J, Pascual E, García Pérez M, Gómez Gallego R, Hidalgo Mora J, Cano Sanchez A. Journal Of Assisted Reproduction And Genetics. 2020 Feb;37(2):493. doi: 10.1007/s10815-019-01671-y. PMID: 31867687

A predictive model for women’s assisted fecundity before starting the first IVF/ICSI treatment cycle. Tarin Folgado J, Pascual E, García Pérez M, Gómez Gallego R, Hidalgo Mora J, Cano Sanchez A. Journal of Assisted Reproduction and Genetics. 2020 Jan;37(1):171-180. doi: 10.1007/s10815-019-01642-3. PMID: 31797243

Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs. Fuggle N, Cooper C, Harvey N, Al-Daghri N, Brandi M, Bruyere O, Cano Sanchez A, Dennison E, Diez-Perez A, Kaufman J, Palacios S, Prieto-Alhambra D, Rozenberg S, Thomas T, Tremollieres F, Rizzoli R, Kanis J, Reginster J. Drugs. 2020 Oct;80(15):1537-1552. doi: 10.1007/s40265-020-01364-2. PMID: 32725307

Association of a single nucleotide polymorphism of RANK gene with blood pressure in Spanish women. Pertusa Viñuales C, Tarin Folgado J, Cano Sanchez A, García Pérez M. Medicine. 2020 Oct 2;99(40):e22436. doi: 10.1097/MD.0000000000022436. PMID: 33019425

Can Integrated Care Help in Meeting the Challenges Posed on Our Health Care Systems by COVID-19? Some Preliminary Lessons Learned from the European VIGOUR Project. Lindner S, Kubitschke L, Lionis C, Anastasaki M, Kirchmayer U, Giacomini S, De Luca V, Laccarino G, Illario M, Maddalena A, Maritati A, Conforti D, Roba I, Musian D, Cano A, Granell M, Carriazo A, Lama C, Rodriguez S, Guligowska A, Kostka T, Konijnendijk A, Vitullo M, Garcia-Rudolph A, Sanchez J, Maggio M, Liotta G, Tziraki C, Roller-Wirnsberger R, VIGOUR Consortium. International Journal of Integrated Care. 2020 Oct 19;20(4):4. doi: 10.5334/ijic.5596. PMID: 33132789

Combination of phenotype and polygenic risk score in breast cancer risk evaluation in the Spanish population: a case -control study. Trivino J, Ceba A, Rubio-Solsona E, Serra D, Sanchez-Guiu I, Ribas G, Rosa R, Cabo M, Bernad L, Pita G, Gonzalez-Neira A, Legarda G, Diaz J, García Vigara A, Martinez Aspas A, Escrig M, Bermejo De Las Heras B, Eroles Asensio P, Ibanez J, Salas D, Julve Parreño A, Cano Sanchez A, Lluch Hernández A, Minambres R, Benitez J. BMC Cancer.2020 Nov 10;20(1):1079. doi: 10.1186/s12885-020-07584-9. PMID: 33167914

Comparative transcriptome analysis identifies CARM1 and DNMT3A as genes associated with osteoporosis. Panach Gonzalez L, Pertusa Viñuales C, Martinez Rojas B, Acebrón Fabregat Á, Mifsut Miedes D, Tarin Folgado J, Cano Sanchez A, García Pérez M. Scientific Reports. 2020 Oct 1;10(1):16298. doi: 10.1038/s41598-020-72870-2. PMID: 33004909

Cumulative probabilities of live birth across multiple complete IVF/ICSI cycles: a call for attention. Tarin Folgado J, Pascual E, Perez-Hoyos S, Gómez Gallego R, García Pérez M, Cano Sanchez A. Journal of Assisted Reproduction and Genetics. 2020 Jan;37(1):141-148. doi: 10.1007/s10815-019-01608-5. PMID: 31808046

Diet to Reduce the Metabolic Syndrome Associated with Menopause. The Logic for Olive Oil. Hidalgo-Mora J, Cortes-Sierra L, Garcia-Perez M, Tarin J, Cano A. Nutrients. 2020 Oct 18;12(10):3184. doi: 10.3390/nu12103184. PMID: 33081027

Differential expression of Receptor Activator of Nuclear Factor Kappa B in healthy endometrium, ovarian endometrioma and endometrioid ovarian cancer. Gregori Romero M, Rodriguez Garcia V, Burgues Gasion O, Martinez Carmona J, Tarin Folgado J, Cano Sanchez A, Gómez Gallego R. American Journal of Obstetrics and Gynecology. 2020 Mar;222(3):279-281. doi: 10.1016/j.ajog.2019.11.1259. PMID: 31765641

Imaging in gynecological disease: clinical and ultrasound features of extra gastrointestinal stromal tumors (eGIST). Ambrosio M, Testa A, Moro F, Franchi D, Scifo M, Rams N, Epstein E, Alcazar J, Hidalgo Mora J, Van Holsbeke C, Burgetova A, Dundr P, Cibula D, Fischerova D. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2020 Nov;56(5):749-758. doi: 10.1002/uog.21968. PMID: 31909545

Impact of progestin ovarian stimulation on newborn outcomes: a meta-analysis. Zolfaroli I, Arribas Ferriol G, Hidalgo Mora J, Cano Sanchez A. Journal Of Assisted Reproduction And Genetics. 2020 May;37(5):1203-1212. doi: 10.1007/s10815-020-01755-0. PMID: 32215824

Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?. Rozenberg S, Al-Daghri N, Aubertin-Leheudre M, Brandi M, Cano Sanchez A, Collins P, Cooper C, Genazzani A, Hillard T, Kanis J, Kaufman J, Lambrinoudaki I, Laslop A, McCloskey E, Palacios S, Prieto-Alhambra D, Reginster J, Rizzoli R, Rosano G, Tremollieres F, Harvey N. Osteoporosis international. 2020 Dec;31(12):2271-2286. doi: 10.1007/s00198-020-05497-8. PMID: 32642851

Management of depressive symptoms in peri- and postmenopausal women: EMAS position statement. Stute P, Spyropoulou A, Karageorgiou V, Cano Sanchez A, Bitzer J, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis D, Linden Hirschberg A, Kiesel L, Lopes P, Pines A, Rees M, van Trotsenburg M, Zervas I, Lambrinoudaki I. Maturitas. 2020 Jan;131:91-101. doi: 10.1016/j.maturitas.2019.11.002. PMID: 31740049

Managing thromboembolic risk with menopausal hormone therapy and hormonal contraception in the COVID-19 pandemic: Recommendations from the Spanish Menopause Society, Sociedad Espanola de Ginecologia y Obstetricia and Sociedad Espanola de Trombosis y Hemostasia. Ramirez I, De la Viuda E, Baquedano L, Coronado P, Llaneza P, Mendoza N, Otero B, Sanchez S, Jesus Cancelo M, Antonio Paramo J, Cano Sanchez A. Maturitas. 2020 Jul;137:57-62. doi: 10.1016/j.maturitas.2020.04.019. PMID: 32498938

Mediterranean diet and health: A systematic review of epidemiological studies and intervention trials. Sanchez Sanchez M, García Vigara A, Hidalgo Mora J, García Pérez M, Tarin Folgado J, Cano Sanchez A. Maturitas. 2020 Jun;136:25-37. doi: 10.1016/j.maturitas.2020.03.008. PMID: 32386663

Menopausal Hormone Therapy and breast cancer risk: Individualization is the key to safety. Armeni E, Cano Sanchez A, Rees M, Lambrinoudaki I. Maturitas. 2020 Nov;141:85-86. doi: 10.1016/j.maturitas.2020.08.001. PMID: 32861483

Menopause symptom management in women with dyslipidemias: An EMAS clinical guide. Anagnostis P, Bitzer J, Cano Sanchez A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis D, Hirschberg A, Kiesel L, Lopes P, Pines A, van Trotsenburg M, Lambrinoudaki I, Rees M. Maturitas. 2020 May;135:82-88. doi: 10.1016/j.maturitas.2020.03.007. PMID: 32209279

Polymorphisms in genes involved in T-cell co-stimulation are associated with blood pressure in women. Pineda Merlo B, Pertusa Viñuales C, Panach Gonzalez L, Tarin Folgado J, Cano Sanchez A, García Pérez M. Gene. 2020 Sep 5;754:144838. doi: 10.1016/j.gene.2020.144838. PMID: 32525043

Predictors of live birth in women with a history of biochemical pregnancies after assisted reproduction treatment. Tarin Folgado J, Pascual Castello E, Gómez Gallego R, García Pérez M, Cano Sanchez A. European journal of obstetrics, gynecology, and reproductive biology. 2020 May;248:198-203. PMID: 32240893

Response to «Should estrogen be used in the co-treatment of COVID-19 patients?». Cano A, Ramirez I, De la Viuda E, Baquedano L, Coronado P, Llaneza P, Otero B, Sanchez S, Cancelo M, Paramo J, Mendoza N. Maturitas. 2020 Oct;140:81-82. doi: 10.1016/j.maturitas.2020.06.014. PMID: 32747134

The Mediterranean diet and menopausal health: An EMAS position statement. Cano Sanchez A, Marshall S, Zolfaroli I, Bitzer J, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis D, Hirschberg A, Kiesel L, Lopes P, Pines A, van Trotsenburg M, Lambrinoudaki I, Rees M. Maturitas. 2020 Sep;139:90-97. doi: 10.1016/j.maturitas.2020.07.001. PMID: 32682573

The Mediterranean diet: A historical perspective on food for health. Hidalgo Mora J, García Vigara A, Sanchez Sanchez M, García Pérez M, Tarin Folgado J, Cano Sanchez A. Maturitas. 2020 Feb;132:65-69. doi: 10.1016/j.maturitas.2019.12.002. PMID: 31883665

The thromboembolic risk in covid-19 women under hormonal treatment group. Ramirez I, De la Viuda E, Baquedano L, Coronado P, Llaneza P, Mendoza N, Otero B, Sanchez S, Cancelo M, Paramo J, Cano Sanchez A. Maturitas. 2020 Aug;138:78-79. doi: 10.1016/j.maturitas.2020.05.021. PMID: 32565010

Transplantation of ACE2(-) Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia. Leng Z, Zhu R, Hou W, Feng Y, Yang Y, Han Q, Shan G, Meng F, Du D, Wang S, Fan J, Wang W, Deng L, Shi H, Li H, Hu Z, Zhang F, Gao J, Liu H, Li X, Zhao Y, Yin K, He X, Gao Z, Wang Y, Yang B, Jin R, Stambler I, Lim L, Su H, Moskalev A, Cano Sanchez A, Chakrabarti S, Min K, Ellison-Hughes G, Caruso C, Jin K, Zhao R. Aging and Disease. 2020 Mar 9;11(2):216-228. doi: 10.14336/AD.2020.0228. PMID: 32257537

Proyectos
Referencia: AC19/00084
Título: Patrones dietéticos en población europea senescente: acercamiento multidisciplinar para combatir las enfermedades metabólicas ligadas a sobrepeso. Proyecto EURODIET
Entidad Financiadora: European Commission (Programación conjunta internacional ISCIII)
Investigador principal: Antonio Cano Sánchez
Duración: 2020 – 2022
Presupuesto: 27225

Referencia: 826640-VIGOUR
Título: Evidence-Based Guidance to Scale-up Integrated Care in Europe (VIGOUR)
Entidad Financiadora: Agencia Ejecutiva de Consumidores, Salud, Agricultura y Alimentación
Investigador principal: Antonio Cano Sánchez, Juan J. Tarín, Miguel Ángel García Pérez
Duración: 2019 – 2021
Presupuesto: 3.046.024,67

Referencia: 696300 – EURODIET
Título: EURODIET Dietary Patterns in the Ageing European Population: an Interdisciplinary Approach to combat Overweight-Related Metabolic Diseases. The EURODIET project
Entidad Financiadora: European Commission (Programación conjunta internacional ISCIII)
Investigador principal: Antonio Cano Sánchez
Duración: 2019 – 2020
Presupuesto: 455.915,00 €

+ Información
Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide. Hirschberg AL, Bitzer J, Cano A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis DG, Kiesel L, Lopes P, Pines A, van Trotsenburg M, Lambrinoudaki I, Rees M. Maturitas. 2021 Jun;148:55-61. doi: 10.1016/j.maturitas.2021.04.005. PMID: 33896654

Menopause symptom management in women with dyslipidemias: An EMAS clinical guide. Anagnostis P, Bitzer J, Cano Sanchez A, Ceausu I, Chedraui P, Durmusoglu F, Erkkola R, Goulis D, Hirschberg A, Kiesel L, Lopes P, Pines A, van Trotsenburg M, Lambrinoudaki I, Rees M. Maturitas. 2020 May;135:82-88. doi: 10.1016/j.maturitas.2020.03.007. PMID: 32209279

Título: Acción del bazedoxifeno sobre el metabolismo óseo y los factores de riesgo cardiovascular
Doctorando: Carrasco Catena, María Amparo
Director: Cano Sánchez, Antonio; Monleón Sancho, Francisco Javier
Fecha: 20/11/2020
Universidad: Universitat de València

Título: Efectos de las enfermedades de las mujeres sobre resultados FIV/ICSI y la utilización de probabilidades acumuladas de nacimiento vivo como único método de predicción
Doctorando: Pascual Castelló, Eva Cristina
Director: Tarín Folgado, Juan José
Fecha: 05/10/2020
Universidad: Universitat de València

Título: Vivencias en relación con la mutilación genital femenina y capacitación para su abordaje desde los diferentes actores institucionales implicados en valencia
Doctorando: González Timoneda, Alba
Director: Ruiz Ros, Vicente; Cano Sánchez, Antonio
Fecha: 23/07/2020
Universidad: Universitat de València

Título: Impact of bazedoxifene on endothelial health markers
Doctorando: Dudenko Lozenko, Darya
Director: Cano Sánchez, Antonio; Tarín Folgado, Juan José; Gómez Gallego, Raúl
Fecha: 30/06/2020
Universidad: Universitat de València

Título: Tratamiento del mioma con acetato de ulipristal: control evolutivo con ecografía/angiografía tridimensional
Doctorando: Pascual Botía, Carlos
Director: Raga Bauxauli, Francisco; Cano Sánchez, Antonio
Fecha: 13/03/2020
Universidad: Universitat de València

Título: Lipidograma y metabolismo óseo, estudio clínico y analítico en la cohorte «CARMEN»
Doctorando: Zolfaroli, Irene
Director: García Pérez, Miguel Ángel; Cano Sánchez, Antonio
Fecha: 27/02/2019
Universidad: Universitat de València

Título: Evaluación estandarizada del potencial antiangiógénico del agonista dopaminérgico en el tratamiento de la endometriosis
Doctorando: Blanca Ruiz, Taqua
Director: Cano Sánchez, Antonio; Gómez Gallego, Raúl
Fecha: 17/01/2019
Universidad: Universitat de València