Dr. Julio Sanjuán Arias

Investigador Principal
Grupo de Investigación en Psiquiatría y Enfermedades Neurodegenerativas

Presentación


Profesor Titular de Psiquiatría de la Facultad de Medicina de Valencia. Responsable de la Unidad de primeros Episodios Psicóticos del Hospital Clínico de Valencia. Ha publicado 223 artículos en revistas indexadas. Indice H = 31.

Autor de: ¿Tratar la Mente o Tratar el Cerebro? Hacia una integración entre psicoterapia y psicofármacos. (Desclée 2016) coordinador de 7 libros y autor de 54 capitulos.

Su grupo de investigación está involucrado en la actualidad en 10 proyectos activos en convocatorias nacionales e internacionales. Una muestra de su investigación actual se puede encontrar en:
https://www.rtve.es/alacarta/videos/comando-actualidad/app-para-atajar-psicosis/5503979/

Dr. Julio Sanjuán Arias
Investigador
Principal
Dr. Julio Sanjuán Arias

julio.sanjuan@uv.es

Publicaciones
Cognition and social functioning in first episode psychosis: a systematic review of longitudinal studies. Montaner-Ferrer M, Gadea M, Sanjuan J. Frontiers in Psychiatry. 2023 Mar 6;14:1055012. doi: 10.3389/fpsyt.2023.1055012. PMID: 36950257

Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: results from the EUGEI study. Fusar-Poli L, Prachason T, Erzin G, Pries L, Brondino N, Politi P, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altinyazar V, Yalincetin B, Gumus-Akay G, Cihan B, Soygur H, Ulas H, Cankurtaran E, Kaymak S, Mihaljevic M, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, Garcia-Portilla M, Sanjuan J, Escarti M, Santos J, Jimenez-Lopez E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Maric N, Atbasoglu C, Ucok A, Alptekin K, Saka M, Arango C, O’Donovan M, van Os J, Rutten B, Guloksuz S. Psychiatry Research. 2023 May;323:115184. doi: 10.1016/j.psychres.2023.115184. PMID: 37015164

Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study. Alameda L, Liu Z, Sham P, Aas M, Trotta G, Rodriguez V, Di Forti M, Stilo S, Kandaswamy R, Arango C, Arrojo M, Bernardo M, Bobes J, de Haan L, Del-Ben C, Gayer-Anderson C, Sideli L, Jones P, Jongsma H, Kirkbride J, La Cascia C, Lasalvia A, Tosato S, Llorca P, Menezes P, van Os J, Quattrone D, Rutten B, Santos J, Sanjuan J, Selten J, Szoke A, Tarricone I, Tortelli A, Velthorst E, Morgan C, Dempster E, Hannon E, Burrage J, Dwir D, Arumuham A, Mill J, Murray R, Wong C. Molecular Psychiatry. 2023 Apr 17. doi: 10.1038/s41380-023-02044-9. PMID: 37062770

Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study. Aas M, Alameda L, Di Forti M, Quattrone D, Dazzan P, Trotta A, Ferraro L, Rodriguez V, Vassos E, Sham P, Tripoli G, La Cascia C, La Barbera D, Tarricone I, Muratori R, Berardi D, Lasalvia A, Tosato S, Szoke A, Llorca P, Arango C, Tortelli A, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuan J, Santos J, Arrojo M, Del-Ben C, Menezes P, Selten J, Jones P, Jongsma H, Kirkbride J, Rutten B, van Os J, Gayer-Anderson C, Murray R, Morgan C. Psychological Medicine. 2023 Apr;53(5):1970-1978. doi: 10.1017/S0033291721003664. PMID: 37310339

The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study. Spinazzola E, Quattrone D, Rodriguez V, Trotta G, Alameda L, Tripoli G, Gayer-Anderson C, Freeman T, Johnson E, Jongsma H, Stilo S, La Cascia C, Ferraro L, La Barbera D, Lasalvia A, Tosato S, Tarricone I, D’Andrea G, Galatolo M, Tortelli A, Tagliabue I, Turco M, Pompili M, Selten J, de Haan L, Menezes P, Del Ben C, Santos J, Arrojo M, Bobes J, Sanjuan J, Bernardo M, Arango C, Kirkbride J, Jones P, O’Donovan M, Rutten B, Van Os J, Morgan C, Sham P, Austin-Zimmerman I, Li Z, Vassos E, Murray R, Di Forti M. Psychological Medicine. 2023 May 2;1-10. doi: 10.1017/S0033291723001071. PMID: 37129249

The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study. Sideli L, Aas M, Quattrone D, La Barbera D, La Cascia C, Ferraro L, Alameda L, Velthorst E, Trotta G, Tripoli G, Schimmenti A, Fontana A, Gayer-Anderson C, Stilo S, Seminerio F, Sartorio C, Marrazzo G, Lasalvia A, Tosato S, Tarricone I, Berardi D, D’Andrea G, Arango C, Arrojo M, Bernardo M, Bobes J, Sanjuan J, Santos J, Menezes P, Del-Ben C, Jongsma H, Jones P, Kirkbride J, Llorca P, Tortelli A, Pignon B, de Haan L, Selten J, Van Os J, Rutten B, Bentall R, Di Forti M, Murray R, Morgan C, Fisher H. Social Psychiatry and Psychiatric Epidemiology. 2023 Jun 19. doi: 10.1007/s00127-023-02513-0. PMID: 37335320

Tobacco use in first-episode psychosis, a multinational EU-GEI study. Sanchez-Gutierrez T, Rodriguez-Toscano E, Roldan L, Ferraro L, Parellada M, Calvo A, Lopez G, Rapado-Castro M, La Barbera D, La Cascia C, Tripoli G, Di Forti M, Murray R, Quattrone D, Morgan C, van Os J, Garcia-Portilla P, Al-Halabi S, Bobes J, de Haan L, Bernardo M, Santos J, Sanjuan J, Arrojo M, Ferchiou A, Szoke A, Rutten B, Stilo S, D’Andrea G, Tarricone I, Diaz-Caneja C, Arango C. Psychological Medicine. 2023 Apr 26;1-12. doi: 10.1017/S0033291723000806. PMID: 37185055

A polygenic approach to the association between smoking and schizophrenia. Al-Soufi L, Martorell L, Molto MD, Gonzalez-Penas J, Garcia-Portilla MP, Arrojo M, Rivero O, Gutierrez-Zotes A, Nacher J, Muntane G, Paz E, Paramo M, Bobes J, Arango C, Sanjuan J, Vilella E, Costas J. Addiction Biology. 2022 Jan;27(1):e13104. doi: 10.1111/adb.13104. PMID: 34779080

A replication study of JTC bias, genetic liability for psychosis and delusional ideation. Henquet C, van Os J, Pries L, Rauschenberg C, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altinyazar V, Yalincetin B, Gumus-Akay G, Cihan B, Soygur H, Ulas H, Cankurtaran E, Kaymak S, Mihaljevic M, Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, Garcia-Portilla M, Sanjuan Arias J, Aguilar Garcia Iturrospe E, Santos J, Jimenez-Lopez E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Maric N, Atbasoglu C, Ucok A, Alptekin K, Saka M, Arango C, O’Donovan M, Rutten B, Guloksuz S. Psychological Medicine. 2022 Jul;52(9):1777-1783. doi: 10.1017/S0033291720003578. PMID: 33046166

Alterations in the volume of thalamic nuclei in patients with schizophrenia and persistent auditory hallucinations. Perez-Rando M, Elvira U, Garcia-Marti G, Gadea M, Aguilar E, Escarti M, Ahullo-Fuster M, Grasa E, Corripio I, Sanjuan J, Nacher J. NeuroImage Clinical. 2022 Jun 1;35:103070. doi: 10.1016/j.nicl.2022.103070. PMID: 35667173

Brain activity changes with emotional words in different stages of psychosis. Soldevila-Matias P, Garcia-Marti G, Fuentes-Dura I, Ruiz JC, Gonzalez-Navarro L, Gonzalez-Vivas C, Radua J, Sanjuan J. European Psychiatry. 2022 Oct 4;1-27. doi: 10.1192/j.eurpsy.2022.2321. PMID: 36193735

Child maltreatment, migration and risk of first-episode psychosis: results from the multinational EU-GEI study. D’Andrea G, Lal J, Tosato S, Gayer-Anderson C, Jongsma H, Stilo S, van der Ven E, Quattrone D, Velthorst E, Berardi D, Menezes P, Arango C, Parellada M, Lasalvia A, La Cascia C, Ferraro L, La Barbera D, Sideli L, Bobes J, Bernardo M, Sanjuan J, Santos J, Arrojo M, Del-Ben C, Tripoli G, Llorca P, de Haan L, Selten J, Tortelli A, Szoke A, Muratori R, Rutten B, van Os J, Jones P, Kirkbride J, Murray R, di Forti M, Tarricone I, Morgan C. Psychological Medicine. 2022 Oct 28;1-11. doi: 10.1017/S003329172200335X. PMID: 36305570

Childhood maltreatment, educational attainment, and IQ: findings from a Multicentric Case-control Study of First-episode Psychosis (EU-GEI). Sideli L, Schimmenti A, La Barbera D, La Cascia C, Ferraro L, Aas M, Alameda L, Velthorst E, Fisher H, Caretti V, Trotta G, Tripoli G, Quattrone D, Gayer-Anderson C, Seminerio F, Sartorio C, Marrazzo G, Lasalvia A, Tosato S, Tarricone I, Berardi D, D’Andrea G, Arango C, Arrojo M, Bernardo M, Bobes J, Sanjuan J, Santos J, Menezes P, Del-Ben C, Jongsma H, Jones P, Kirkbride J, Llorca P, Tortelli A, Pignon B, de Haan L, Selten J, Van Os J, Rutten B, Di Forti M, Morgan C, Murray R, EU-GEI WP2 Group. Schizophrenia Bulletin. 2022 May 7;48(3):575-589. doi: 10.1093/schbul/sbac004. PMID: 35137235

Different measures for auditory hallucinations in populations with psychosis. The Validation of the Spanish versions of the Auditory Vocal Hallucination Rating Scale (AVHRS) and the Positive and Useful Voices Inquiry (PUVI). Lorente-Rovira E, Grasa E, Ochoa S, Corripio I, Pelaez T, Lopez-Carrilero R, Gutierrez-Gea A, Morano-Guillen M, Villagran J, Bartels-Velthuis A, Jenner J, Sanjuan J. Revista de Psiquiatria y Salud Mental. 2022 Oct-Dec;15(4):259-271. doi: 10.1016/j.rpsmen.2020.03.002. PMID: 36513402

Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway. van Os J, Pries L, Ten Have M, de Graaf R, van Dorsselaer S, Delespaul P, Bak M, Kenis G, Lin B, Luykx J, Richards A, Akdede B, Binbay T, Altinyazar V, Yalincetin B, Gumus-Akay G, Cihan B, Soygur H, Ulas H, Cankurtaran E, Kaymak S, Mihaljevic M, Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, Garcia-Portilla M, Sanjuan Arias J, Aguilar Garcia Iturrospe E, Santos J, Jimenez-Lopez E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Maric N, Atbasoglu C, Ucok A, Alptekin K, Saka M, Arango C, O’Donovan M, Rutten B, Guloksuz S. Psychological Medicine. 2022 Jul;52(10):1910-1922. doi: 10.1017/S0033291720003748. PMID: 33070791

Facial emotion recognition in psychosis and associations with polygenic risk for schizophrenia: findings from the multi-center EU-GEI case-control study. Tripoli G, Quattrone D, Ferraro L, Gayer-Anderson C, La Cascia C, La Barbera D, Sartorio C, Seminerio F, Rodriguez V, Tarricone I, Berardi D, Jamain S, Arango C, Tortelli A, Llorca P, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuan J, Santos J, Arrojo M, Del-Ben C, Menezes P, van der Ven E, Jones P, Jongsma H, Kirkbride J, Tosato S, Lasalvia A, Richards A, O’Donovan M, Rutten B, van Os J, Morgan C, Sham P, Di Forti M, Murray R, Murray G. Schizophrenia Bulletin. 2022 Sep 1;48(5):1104-1114. doi: 10.1093/schbul/sbac022. PMID: 35325253

Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study. Pignon B, Peyre H, Ayrolles A, Kirkbride JB, Jamain S, Ferchiou A, Richard JR, Baudin G, Tosato S, Jongsma H, de Haan L, Tarricone I, Bernardo M, Velthorst E, Braca M, Arango C, Arrojo M, Bobes J, Del-Ben CM, Di Forti M, Gayer-Anderson C, Jones PB, La Cascia C, Lasalvia A, Menezes PR, Quattrone D, Sanjuan J, Selten JP, Tortelli A, Llorca PM, van Os J, Rutten BPF, Murray RM, Morgan C, Leboyer M, Szoke A, Schurhoff F. Epidemiology and Psychiatric Sciences. 2022 Sep 27;31:e68. doi: 10.1017/S2045796022000464. PMID: 36165168

How voices change the brain. Two fMRI follow-up case reports. Gonzalez-Vivas C, Valdes-Florido MJ, Garcia-Marti G, Soldevila-Matias P, Marti-Bonmati L, Nacher J, Sanjuan J. Schizophrenia Research. 2022 Oct;248:329-330. doi: 10.1016/j.schres.2022.09.016. PMID: 36155306

Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Indonesia Schizophrenia Consortium, PsychENCODE, Psychosis Endophenotypes International Consortium, SynGO Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. PMID: 35396580

Precuneus and insular hypoactivation during cognitive processing in first-episode psychosis: Systematic review and meta-analysis of fMRI studies. Soldevila-Matías P, Albajes-Eizagirre A, Radua J, García-Martí G, Rubio JM, Tordesillas-Gutierrez D, Fuentes-Durá I, Solanes A, Fortea L, Oliver D, Sanjuán J. Revista de Psiquiatria y Salud Mental. 2022 Apr-Jun;15(2):101-116. doi: 10.1016/j.rpsmen.2022.06.004. PMID: 35840277

The association between cannabis use and facial emotion recognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. Fusar-Poli L, Pries LK, van Os J, Radhakrishnan R, Pence AY, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Akdede B, Binbay T, Altinyazar V, Yalincetin B, Gumus-Akay G, Cihan B, Soygur H, Ulas H, Cankurtaran ES, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, Garcia-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jimenez-Lopez E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Maric NP, Atbasoglu C, Ucok A, Alptekin K, Saka MC, Aguglia E, Arango C, Rutten BP, Guloksuz S. European Neuropsychopharmacology. 2022 Aug 30;63:47-59. doi: 10.1016/j.euroneuro.2022.08.003. PMID: 36055075

The effect of early life events on glucose levels in first-episode psychosis. Garcia-Rizo C, Cabrera B, Bioque M, Mezquida G, Lobo A, Gonzalez-Pinto A, Diaz-Caneja C, Corripio I, Vieta E, Baeza I, Garcia-Portilla M, Gutierrez-Fraile M, Rodriguez-Jimenez R, Garriga M, Fernandez-Egea E, Bernardo M. Frontiers in Endocrinology. 2022 Dec 5;13:983792. doi: 10.3389/fendo.2022.983792. PMID: 36545332

The incidence of psychotic disorders among migrants and minority ethnic groups in Europe: findings from the multinational EU-GEI study. Termorshuizen F, van der Ven E, Tarricone I, Jongsma H, Gayer-Anderson C, Lasalvia A, Tosato S, Quattrone D, La Cascia C, Szoke A, Berardi D, Llorca P, de Haan L, Velthorst E, Bernardo M, Sanjuan Arias J, Arrojo M, Murray R, Rutten B, Jones P, van Os J, Kirkbride J, Morgan C, Selten J. Psychological Medicine. 2022 May;52(7):1376-1385. doi: 10.1017/S0033291720003219. PMID: 32958094

Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings. Velthorst E, Mollon J, Murray R, de Haan L, Germeys I, Glahn D, Arango C, van der Ven E, Di Forti M, Bernardo M, Guloksuz S, Delespaul P, Mezquida G, Amoretti S, Bobes J, Saiz P, Garcia-Portilla M, Santos J, Jimenez-Lopez E, Sanjuan J, Aguilar E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Atbasoglu C, Saka M, Ucok A, Alptekin K, Akdede B, Binbay T, Altinyazar V, Ulas H, Yalincetin B, Gumus-AkaY G, Beyaz B, Soygur H, Cankurtaran E, Kaymak S, Maric N, Mihaljevic M, Petrovic S, Mirjanic T, Del-Ben C, Ferraro L, Gayer-Anderson C, Jones P, Jongsma H, Kirkbride J, La Cascia C, Lasalvia A, Tosato S, Llorca P, Menezes P, Morgan C, Quattrone D, Menchetti M, Selten J, Szoke A, Tarricone I, Tortelli A, McGuire P, Valmaggia L, Kempton M, van der Gaag M, Riecher-Rossler A, Bressan R, Barrantes-Vidal N, Nelson B, McGorry P, Pantelis C, Krebs M, Ruhrmann S, Sachs G, Rutten B, van Os J, Alizadeh B, van Amelsvoort T, Bartels-Velthuis A, Bruggeman R, van Beveren N, Luykx J, Cahn W, Simons C, Kahn R, Schirmbeck F, van Winkel R, Reichenberg A, EU-GEI High Risk Study. Molecular Psychiatry. 2021 Aug;26(8):4529-4543. doi: 10.1038/s41380-020-00969-z. PMID: 33414498

Duration of untreated psychosis in first-episode psychosis is not associated with common genetic variants for major psychiatric conditions: results from the multi-center EU-GEI Study. Ajnakina O, Rodriguez V, Quattrone D, di Forti M, Vassos E, Arango C, Berardi D, Bernardo M, Bobes J, de Haan L, Del-Ben CM, Gayer-Anderson C, Jongsma HE, Lasalvia A, Tosato S, Llorca PM, Menezes PR, Rutten BP, Santos JL, Sanjuan J, Selten JP, Szoke A, Tarricone I, D’Andrea G, Richards A, Tortelli A, Velthorst E, Jones PB, Arrojo Romero M, La Cascia C, Kirkbride JB, van Os J, O’Donovan M, Murray RM. Schizophrenia Bulletin. 2021 Oct 21;47(6):1653-1662. doi: 10.1093/schbul/sbab055. PMID: 33963865

FOXP2 expression and gray matter density in the male brains of patients with schizophrenia. Sanjuan Arias J, Castro-Martinez X, Garcia Marti G, Gonzalez-Fernandez J, Sanz-Requena R, Haro J, Meana J, Marti-Bonmati L, Nacher Roselló J, Sebastia Ortega N, Gilabert Juan J, Moltó Ruiz M. Brain Imaging and Behavior. 2021 Jun;15(3):1403-1411. doi: 10.1007/s11682-020-00339-x. PMID: 32734433

Jumping to conclusions, general intelligence, and psychosis liability: findings from the multi-centre EU-GEI case-control study.. Tripoli G, Quattrone D, Ferraro L, Gayer-Anderson C, Rodriguez V, La Cascia C, La Barbera D, Sartorio C, Seminerio F, Tarricone I, Berardi D, Szoke A, Arango C, Tortelli A, Llorca P, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuan Arias J, Santos J, Arrojo M, Del-Ben C, Menezes P, Selten J, Jones P, Jongsma H, Kirkbride J, Lasalvia A, Tosato S, Richards A, O’Donovan M, Rutten B, Os J, Morgan C, Sham P, Murray R, Murray G, Di Forti M, EU-GEI WP2 Group. Psychological Medicine. 2021 Mar;51(4):623-633. doi: 10.1017/S003329171900357X. PMID: 32327005

Migration history and risk of psychosis: results from the multinational EU-GEI study. Tarricone I, D’Andrea G, Jongsma H, Tosato S, Gayer-Anderson C, Stilo S, Suprani F, Iyegbe C, van der Ven E, Quattrone D, di Forti M, Velthorst E, Rossi Menezes P, Arango C, Parellada M, Lasalvia A, La Cascia C, Ferraro L, Bobes J, Bernardo M, Sanjuan I, Santos J, Arrojo M, Del-Ben C, Tripoli G, Llorca P, de Haan L, Selten J, Tortelli A, Szoke A, Muratori R, Rutten B, van Os J, Jones P, Kirkbride J, Berardi D, Murray R, Morgan C. Psychological Medicine. 2021 Feb 10;1-13. doi: 10.1017/S003329172000495X. PMID: 33563347

Motor abnormalities and basal ganglia in first-episode psychosis (FEP). Cuesta M, Lecumberri P, Moreno-Izco L, Lopez-Ilundain J, Ribeiro M, Cabada T, Lorente-Omenaca R, de Erausquin G, Garcia Marti G, Sanjuan Arias J, Sanchez-Torres A, Gomez M, Peralta V. Psychological Medicine. 2021 Jul;51(10):1625-1636. doi: 10.1017/S0033291720000343. PMID: 32114994

Neuroimaging correlates of insight in non-affective psychosis: a systematic review and meta-analysis. Soldevila-Matias P, Schoretsanitis G, Tordesillas-Gutierrez D, Cuesta M, de Filippis R, Ayesa-Arriola R, Gonzalez-Vivas C, Setien-Suero E, Verdolini N, Sanjuan J, Radua J, Crespo-Facorro B. Revista de Psiquiatria y Salud Mental. 2021 Jul 13:S1888-9891(21)00067-7. doi: 10.1016/j.rpsm.2021.07.001. PMID: 34271162

Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study. Misra S, Gelaye B, Williams D, Koenen K, Borba C, Quattrone D, Di Forti M, Tripoli G, La Cascia C, La Barbera D, Ferraro L, Tarricone I, Berardi D, Lasalvia A, Tosato S, Szoke A, Llorca P, Arango C, Tortelli A, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuan J, Santos J, Arrojo M, Del-Ben C, Menezes P, Selten J, Jones P, Jongsma H, Kirkbride J, Rutten B, van Os J, Murray R, Gayer-Anderson C, Morgan C. Psychological Medicine. 2021 Mar 2;1-9. doi: 10.1017/S0033291721000453. PMID: 33648622

Pre-training inter-rater reliability of clinical instruments in an international psychosis research Project. Berendsen S, Kapitein P, Schirmbeck F, van Tricht M, McGuire P, Morgan C, Gayer-Anderson C, Kempton M, Valmaggia L, Quattrone D, di Forti M, van der Gaag M, Kirkbride J, Jongsma H, Jones P, Parellada M, Arango C, Arrojo M, Bernardo M, Sanjuan Arias J, Santos J, Szoke A, Tortelli A, Llorca P, Tarricone I, Tripoli G, Ferraro L, La Cascia C, Lasalvia A, Tosato S, Menezes P, Del-Ben C, Nelson B, Riecher-Rossler A, Bressan R, Barrantes-Vidal N, Krebs M, Nordentoft M, Ruhrmann S, Sachs G, Rutten B, van Os J, Velthorst E, de Haan L, EU-GEI High Risk Study. Schizophrenia Research. 2021 Apr;230:104-107. doi: 10.1016/j.schres.2020.08.001. PMID: 33243716

ReMindCare, an app for daily clinical practice in patients with first episode psychosis: A pragmatic real-world study protocol. Bonet Mora L, Torous J, Arce D, Blanquer I, Sanjuan Arias J. Early Intervention In Psychiatry. 2021 Feb;15(1):183-192. doi: 10.1111/eip.12960. PMID: 32253830

Social disadvantage, linguistic distance, ethnic minority status and first-episode psychosis: results from the EU-GEI case-control study. Jongsma H, Gayer-Anderson C, Tarricone I, Velthorst E, van der Ven E, Quattrone D, di Forti M, Menezes P, Del-Ben C, Arango C, Lasalvia A, Berardi D, La Cascia C, Bobes J, Bernardo M, Sanjuan Arias J, Santos J, Arrojo M, de Haan L, Tortelli A, Szoke A, Murray R, Rutten B, van Os J, Morgan C, Jones P, Kirkbride J, EU-GEI WP2 Group. Psychological Medicine. 2021 Jul;51(9):1536-1548. doi: 10.1017/S003329172000029X. PMID: 32122439

The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis: findings from the EU-GEI study. Quattrone D, Reininghaus U, Richards A, Tripoli G, Ferraro L, Quattrone A, Marino P, Rodriguez V, Spinazzola E, Gayer-Anderson C, Jongsma H, Jones P, La Cascia C, La Barbera D, Tarricone I, Bonora E, Tosato S, Lasalvia A, Szoke A, Arango C, Bernardo M, Bobes J, Del Ben C, Menezes P, Llorca P, Santos J, Sanjuan J, Arrojo M, Tortelli A, Velthorst E, Berendsen S, de Haan L, Rutten B, Lynskey M, Freeman T, Kirkbride J, Sham P, O’Donovan M, Cardno A, Vassos E, van Os J, Morgan C, Murray R, Lewis C, Di Forti M, EU-GEI Collaborators. Translational Psychiatry. 2021 Aug 10;11(1):423. doi: 10.1038/s41398-021-01526-0. PMID: 34376640

The independent effects of psychosocial stressors on subclinical psychosis: findings from the multinational EU-GEI Study. Pignon B, Lajnef M, Kirkbride JB, Peyre H, Ferchiou A, Richard JR, Baudin G, Tosato S, Jongsma H, de Haan L, Tarricone I, Bernardo M, Velthorst E, Braca M, Arango C, Arrojo M, Bobes J, Del-Ben CM, Di Forti M, Gayer-Anderson C, Jones PB, La Cascia C, Lasalvia A, Menezes PR, Quattrone D, Sanjuan J, Selten JP, Tortelli A, Llorca PM, van Os J, Rutten BPF, Murray RM, Morgan C, Leboyer M, Szoke A, Schurhoff F. Schizophrenia Bulletin. 2021 Oct 21;47(6):1674-1684. doi: 10.1093/schbul/sbab060. PMID: 34009318

The relationship of symptom dimensions with premorbid adjustment and cognitive characteristics at first episode psychosis: Findings from the EU-GEI study. Ferraro L, La Cascia C, La Barbera D, Sanchez-Gutierrez T, Tripoli G, Seminerio F, Sartorio C, Marrazzo G, Sideli L, Arango C, Arrojo M, Bernardo M, Bobes J, Del-Ben C, Gayer-Anderson C, Jongsma H, Kirkbride J, Lasalvia A, Tosato S, Llorca P, Menezes P, Rutten B, Santos J, Sanjuan J, Selten J, Szoke A, Tarricone I, Muratori R, Tortelli A, Velthorst E, Rodriguez V, Quattrone A, Jones P, Van Os J, Vassos E, Morgan C, de Haan L, Reininghaus U, Cardno A, Di Forti M, Murray R, Quattrone D. Schizophrenia Research. 2021 Aug 14;236:69-79. doi: 10.1016/j.schres.2021.08.008. PMID: 34403965

Association study of candidate genes with obesity and metabolic traits in antipsychotic-treated patients with first-episode psychosis over a 2-year period. Gasso P, Albert Arnaiz J, Mas S, Lafuente A, Bioque M, Cuesta M, Diaz-Caneja C, Garcia C, Lobo A, Gonzalez-Pinto A, Parellada M, Corripio I, Vieta E, Castro-Fornieles J, Mane A, Rodriguez N, Bolac D, Saiz-Ruiz J, Bernardo M, Mezquida G, Amoretti S, Pina-Camacho L, Gonzalez-Penas J, Alonso-Solis A, Rabetla M, Zorrilla I, Garcia S, Barcones F, Modrego P, Sanjuan Arias J, Nacher Roselló J, Berge D, Monserrat C, Verdolini N, Gil-Badenes J, Baeza I, De La Serna E, Contreras F, Saiz-Masvidal C, Paz Garcia-Portilla M, Bobes J, Gutierrez M, Segarra R, Dompablo M, Rodriguez-Jimenez R, Usall J, Butjosa A, Sarro S, Pomarol-Clotet E, Ibanez A, Ribeiro M, SELVA VERA G, PEPs Grp. Journal of Psychopharmacology. 2020 May;34(5):514-523. doi: 10.1177/0269881120903462. PMID: 32009515

Birth weight and antipsychotic induced weight gain: A prenatal programming approach in the PEPs study. Garcia-Rizo C, Bioque M, Mezquida G, Amoretti S, Cuesta M, Diaz-Caneja C, Mas S, Lobo A, Gonzalez-Pinto A, Fraguas D, Corripio I, Vieta E, Baeza I, Berge D, Fernandez-Egea E, Garriga M, Bernardo M, Sanjuan Arias J, PEPs group. Schizophrenia Research. 2020 Apr;218:292-294. doi: 10.1016/j.schres.2019.12.030. PMID: 32001078

Daily use of high-potency cannabis is associated with more positive symptoms in first-episode psychosis patients: the EU-GEI case-control study. Quattrone D, Ferraro L, Tripoli G, La Cascia C, Quigley H, Quattrone A, Jongsma H, Del Peschio S, Gatto G, Gayer-Anderson C, Jones P, Kirkbride J, La Barbera D, Tarricone I, Berardi D, Tosato S, Lasalvia A, Szoke A, Arango C, Bernardo M, Bobes J, Del Ben C, Menezes P, Llorca P, Santos J, Sanjuan Arias J, Tortelli A, Velthorst E, de Haan L, Rutten B, Lynskey M, Freeman T, Sham P, Cardno A, Vassos E, van Os J, Morgan C, Reininghaus U, Lewis C, Murray R, Di Forti M, EU-GEI group. Psychological Medicine. 2020 Mar 18;51(8):1-9. doi: 10.1017/S0033291720000082. PMID: 32183927

Different measures for auditory hallucinations in populations with psychosis. The Validation of the Spanish versions of the Auditory Vocal Hallucination Rating Scale (AVHRS) and the Positive and Useful Voices Inquiry (PUVI). Lorente Rovira E, Grasa E, Ochoa S, Corripio I, Pelaez T, Lopez-Carrilero R, Gutierrez-Gea A, Morano-Guillen M, Villagran J, Bartels-Velthuis A, Jenner J, Sanjuan Arias J. Revista de Psiquiatria y Salud Mental. 2020 May 31;S1888-9891(20)30027-6. doi: 10.1016/j.rpsm.2020.03.002. PMID: 32493672

Elevated Extracellular Free-Water in a Multicentric First-Episode Psychosis Sample, Decrease During the First 2 Years of Illness. Berge D, Mane A, Lesh T, Bioque M, Barcones F, Gonzalez-Pinto A, Parellada M, Vieta E, Castro-Fornieles J, Rodriguez-Jimenez R, Garcia-Portilla M, Usall J, Carter C, Cabrera B, Bernardo M, Janssen J, Sanjuan Arias J, PEPs group (collaborators). Schizophrenia Bulletin. 2020 Jul 8;46(4):846-856. doi: 10.1093/schbul/sbz132. PMID: 31915835

Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum. Pries L, Dal Ferro G, van Os J, Delespaul P, Kenis G, Lin B, Luykx J, Richards A, Akdede B, Binbay T, Altinyazar V, Yalincetin B, Gumus-Akay G, Cihan B, Soygur H, Ulas H, Sahin Cankurtaran E, Ulusoy Kaymak S, Mihaljevic M, Andric Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, Garcia-Portilla M, Sanjuan Arias J, Aguilar Garcia Iturrospe E, Santos J, Jimenez-Lopez E, Arrojo M, Carracedo A, Lopez G, Gonzalez-Penas J, Parellada M, Maric N, Atbasoglu C, Ucok A, Alptekin K, Can Saka M, Arango C, O’Donovan M, Tosato S, Rutten B, Guloksuz S, Genetic Risk Outcome Psychosis GRP. Epidemiology and Psychiatric Sciences. 2020 Nov 17;29:e182. doi: 10.1017/S2045796020000943. PMID: 33200977

First-Episode Psychotic Patients Showed Longitudinal Brain Changes Using fMRI With an Emotional Auditory Paradigm. Gonzalez-Vivas C, Garcia-Marti G, Soldevila-Matias P, Sanz-Requena R, Aguilar E, Castro-Bleda M, Marti-Bonmati L, Sanjuan J. Frontiers in Psychiatry. 2020 Dec 11;11:593042. doi: 10.3389/fpsyt.2020.593042. PMID: 33424663

Interaction between the functional SNP rs2070951 in NR3C2 gene and high levels of plasma corticotropin-releasing hormone associates to postpartum depression. Gutierrez-Zotes A, Diaz-Pena R, Costas J, Martorell L, Gelabert E, Sans T, Navines R, Albacar G, Imaz M, Garcia-Esteve L, Sanjuan Arias J, Martin-Santos R, Carracedo A, Vilella E. Archives Of Womens Mental Health. 2020 Jun;23(3):413-420. doi: 10.1007/s00737-019-00989-x. PMID: 31388769

Personalized medicine begins with the phenotype: identifying antipsychotic response phenotypes in a first-episode psychosis cohort. Mas S, Gasso P, Rodriguez N, Cabrera B, Mezquida G, Lobo A, Gonzalez-Pinto A, Parellada M, Corripio I, Vieta E, Castro-Fornieles J, Bobes J, Usall J, Saiz-Ruiz J, Contreras F, Parellada E, Bernardo M, Lafuente A, Bioque M, Diaz-Caneja C, Gonzalez-Penas J, Solis A, Rebella M, Gonzalez-Ortega I, Besga A, Sanjuan Arias J, Nacher Roselló J, Morro L, Montserrat C, Jimenez E, Gomes Da Costa S, Baeza I, de la Serna E, Rivas S, Diaz C, Saiz P, Garcia-Alvarez L, Gutierrez Fraile M, Zabala Rabadan A, Torio I, Rodriguez-Jimenez R, Butjosa A, Pardo M, Sarro S, Pomarol-Clotet E, Ibanez Cuadrado A, Cuesta M, PEPs Grp. Acta Psychiatrica Scandinavica. 2020 Jun;141(6):541-552. doi: 10.1111/acps.13131. PMID: 31746462

Positive and Useful Voices in Patients With Schizophrenia: Prevalence, Course, Characteristics, and Correlates. Lorente Rovira E, Grasa E, Ochoa S, Corripio I, Pelaez T, Lopez-Carrillero R, Morano-Guillen M, Gutierrez-Gea A, Villagran J, Llacer B, Sanjuan Arias J. The Journal of nervous and mental disease. 2020 Aug;208(8):587-592. PMID: 32453282

Precuneus and insular hypoactivation during cognitive processing in first-episode psychosis: Systematic review and meta-analysis of fMRI studies. Soldevila Matias P, Albajes-Eizagirre A, Radua J, Garcia Marti G, Rubio J, Tordesillas-Gutierrez D, Fuentes Dura I, Solanes A, Fortea L, Oliver D, Sanjuan Arias J. Revista de Psiquiatria y Salud Mental. 2020 Sep 25;S1888-9891(20)30100-2. doi: 10.1016/j.rpsm.2020.08.001. PMID: 32988773

Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use. Ferraro L, La Cascia C, Quattrone D, Sideli L, Matranga D, Capuccio V, Tripoli G, Gayer-Anderson C, Morgan C, Sami M, Sham P, de Haan L, Velthorst E, Jongsma H, Kirkbride J, Rutten B, Richards A, Roldan L, Arango C, Bernardo M, Bobes J, Sanjuan Arias J, Santos J, Arrojo M, Tarricone I, Tortelli A, Szoke A, Del-Ben C, Selten J, Lynskey M, Jones P, Van Os J, La Barbera D, Murray R, Di Forti M, WP2 EU-GEI GROUP. Schizophrenia Bulletin.2020 Apr 10;46(3):517-529. doi: 10.1093/schbul/sbz077. PMID: 31361020

Psychotic Experiences Are Associated With Paternal Age But Not With Delayed Fatherhood in a Large, Multinational, Community Sample. Schurhoff F, Pignon B, Lajnef M, Denis R, Rutten B, Morgan C, Murray R, Leboyer M, van Os J, Szoke A, Sanjuan Arias J, EU-GEI WP2. Schizophrenia Bulletin. 2020 Feb 12;46(5):1327-1334. doi: 10.1093/schbul/sbz142. PMID: 32049353

ReMindCare App for Early Psychosis: Pragmatic Real World Intervention and Usability Study. BONET MORA L, Torous J, Arce D, Blanquer I, Sanjuan Arias J. JMIR mHealth and uHealth. 2020 Nov 6;8(11):e22997. doi: 10.2196/22997. PMID: 33155986

Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study. van Os J, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome Investigators (GROUP), Arango C, O’Donovan M, Rutten BPF, Guloksuz S. Psychological Medicine. 2020 Aug;50(11):1884-1897. doi: 10.1017/S003329171900196X. PMID: 31414981

Substance use during pregnancy and personality dimensions. Imaz M, Navines R, Gelabert E, Fonseca F, Gutierrez-Zotes A, Guillamat R, Langohr K, Canellas F, Gornemann I, Costas J, Mayoral F, Valles V, De Diego Y, Roca M, Iborra J, Gratacos M, Vilella E, Garcia-Esteve L, Sanjuan Arias J, Torrens M, Martin-Santos Laffon R. Adicciones. 2020 Dec 2;0(0):1433. doi: 10.20882/adicciones.1433. PMID: 3338243

The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Gayer-Anderson C, Jongsma H, Di Forti M, Quattrone D, Velthorst E, de Haan L, Selten J, Szoke A, Llorca P, Tortelli A, Arango C, Bobes J, Bernardo M, Sanjuan J, Santos J, Arrojo M, Parellada M, Tarricone I, Berardi D, Ruggeri M, Lasalvia A, Ferraro L, La Cascia C, La Barbera D, Menezes P, Del-Ben C, Rutten B, van Os J, Jones P, Murray R, Kirkbride J, Morgan C, Moltó Ruiz M, EU-GEI WP2 Grp. Social Psychiatry and Psychiatric Epidemiology. 2020 May;55(5):645-657. doi: 10.1007/s00127-020-01831-x. PMID: 31974809

The role of personality dimensions, depressive symptoms and other psychosocial variables in predicting postpartum suicidal ideation: a cohort study. Gelabert E, Gutierrez-Zotes A, Navines R, Labad J, Puyane M, Donadon M, Guillamat R, Mayoral F, Jover M, Canellas F, Gratacos M, Guitart M, Gornemann I, Roca M, Costas J, Llacer Iborra B, Subira S, de Diego Y, Osorio F, Garcia-Esteve L, Sanjuan Arias J, Vilella E, Martin-Santos R. Archives of Womens Mental Health. 2020 Aug;23(4):585-593. doi: 10.1007/s00737-019-01007-w. PMID: 31802248

Proyectos
Referencia: INVEST/2022/141
Título: Programa de formación y ocupabilidad de psicologo/a en evaluaciones clínicas y uso seguimiento del aplicativo remindcare en proyectos de investigación
Entidad Financiadora: Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital
Investigador principal: Julio Sanjuan Arias
Duración: 2022 – 2024
Presupuesto: 66.218 €
Referencia: PI20/00473
Título: Estudio longitudinal de una cohorte representativa: superando la heterogeneidad clínica y biológica en primeros episodios psicóticos
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Julio Sanjuán Arias
Duración: 2021 – 2023
Presupuesto: 68.970 €
Referencia: PROMETEO/2020/024
Título: Estudio longitudinal de una cohorte representativa: superando la heterogeneidad clínica y biológica en primeros episodios psicóticos
Entidad Financiadora: Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital
Investigador principal: Julio Sanjuán Arias
Duración: 2020 – 2023
Presupuesto: 174.588 €
Referencia: PI17/00402
Título: Resonancia magnética funcional y expresión génica como predictores en primeros episodios psicóticos
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Julio Sanjuán Arias
Duración: 2018 – 2020
Presupuesto: 110.231 €
Referencia: PROMETEO/2016/082
Título: Investigación de marcadores biológicos y nuevas estrategias terapéuticas en la Psicosis
Entidad Financiadora: Conselleria de Educación, Cultura y Deporte
Investigador principal: Julio Sanjuán Arias
Duración: 2016 – 2019
Presupuesto: 179.940 €
Referencia: CB07/09/0006
Título: CIBER de Salud Mental (CIBERSAM)
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Juan Nacher Roselló
Duración: 2008 –
Presupuesto:
+ Información
Título: REMINDCARE: una aplicación para primeros episodios psicóticos integrada en la práctica clínica diaria
Doctorando: Bonet Mora, Lucía
Director: Sanjuán Arias, Julio   
Fecha: 16/07/2021
Universidad: Universitat de València

Título: Resonancia magnética funcional con paradigma emocional en pacientes con un primer episodio psicótico
Doctorando: Soldevila Matías, Pablo
Director: Sanjuan Arias, Julio; Espert Tortajada, Raúl; García Martí, Gracián
Fecha: 28/11/2019
Universidad: Universitat de València