{"id":37167,"date":"2024-07-15T13:00:15","date_gmt":"2024-07-15T11:00:15","guid":{"rendered":"https:\/\/www.incliva.es\/biotool\/"},"modified":"2024-12-20T19:27:21","modified_gmt":"2024-12-20T17:27:21","slug":"biotool","status":"publish","type":"page","link":"https:\/\/www.incliva.es\/en\/services\/researcher-services\/scientific-management\/international\/biotool\/","title":{"rendered":"BIOTOOL"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_2_3 2_3 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\" style=\"width:100%;max-width:400PX;margin-top:20px;margin-bottom:20px;\"><a class=\"fusion-no-lightbox\" href=\"https:\/\/www.biotool-chf.eu\/\" target=\"_blank\" aria-label=\"BIOTOOL-CHF-Logo\" rel=\"noopener noreferrer\"><img width=\"230\" height=\"72\" src=\"https:\/\/www.incliva.es\/wp-content\/uploads\/2024\/06\/BIOTOOL-CHF-Logo.png\" class=\"img-responsive wp-image-31229\" srcset=\"https:\/\/www.incliva.es\/wp-content\/uploads\/2024\/06\/BIOTOOL-CHF-Logo-200x63.png 200w, https:\/\/www.incliva.es\/wp-content\/uploads\/2024\/06\/BIOTOOL-CHF-Logo.png 230w\" sizes=\"(max-width: 640px) 100vw, 230px\" \/><\/a><\/span><\/div><style type=\"text\/css\">@media only screen and (max-width:1532px) {.fusion-title.fusion-title-1{margin-top:10px!important;margin-bottom:15px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-1{margin-top:10px!important;margin-bottom:10px!important;}}<\/style><div class=\"fusion-title title fusion-title-1 fusion-title-text fusion-title-size-one\" style=\"margin-top:10px;margin-bottom:15px;\"><div class=\"title-sep-container title-sep-container-left fusion-no-large-visibility fusion-no-medium-visibility fusion-no-small-visibility\"><div class=\"title-sep sep-single sep-solid\" style=\"border-color:#3d44ac;\"><\/div><\/div><h1 class=\"title-heading-left\" style=\"margin:0;\">BIOTOOL<\/h1><div class=\"title-sep-container title-sep-container-right\"><div class=\"title-sep sep-single sep-solid\" style=\"border-color:#3d44ac;\"><\/div><\/div><\/div><div class=\"fusion-text fusion-text-1\" style=\"transform:translate3d(0,0,0);\"><h6><strong>BIOmarker\u00a0<\/strong>based diagnostic<strong>\u00a0TOOLkit\u00a0<\/strong>to personalize pharmacological approaches in congestive\u00a0<strong>heart failure<\/strong><\/h6>\n<\/div><div class=\"fusion-text fusion-text-2\" style=\"transform:translate3d(0,0,0);\"><p>Heart failure is a chronic clinical syndrome involving up to 6.5 million people in Europe. It is the leading cause of hospitalisation in adults, yielding a healthcare cost of 17 billion euro\/year. The mortality rate is comparable\/superior to several type of cancers in the EU perspective, reaching 70% at 5-year in the advanced stages of heart failure.<\/p>\n<p>The BIOTOOL project seeks to revolutionise the treatment of heart failure with reduced ejection fraction (HF-REF) by offering a more efficient and personalised approach, through innovative tools and digital solutions, to manage diuretic therapy in heart failure with reduced ejection fraction, reduce heart failure hospitalisations and improve patients&#8217; quality of life.<\/p>\n<p>The objectives of BIOTOOL-CHF include the validation of qualified biomarkers estimating congestion, the definition of an artificial intelligence-based score predicting congestion and prognosis, the development of a decision-making tool for diuretic management, the creation of a Point of Care companion diagnostic (CD) for assessing biomarkers concentrations, and the establishment of a Strategy plan for industrial development and market access of the CD.<\/p>\n<p><strong>Consortium<\/strong><\/p>\n<p>El project is made up by a consortium of twenty-four hospitals, universities, and research centers from Italy, Germany, France, the Netherlands, Belgium, Greece, Slovenia, Spain, Denmark, Switzerland, and Sweden.<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#9da0d2;border-top-width:1px;\"><\/div><\/div><div ><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none\" style=\"width:100%;max-width:250px;\"><img width=\"2560\" height=\"537\" title=\"EN-Funded by the EU-POS\" src=\"https:\/\/www.incliva.es\/wp-content\/uploads\/2023\/02\/EN-Funded-by-the-EU-POS-scaled-e1717506232841.jpg\" class=\"img-responsive wp-image-17267\"\/><\/span><\/div><div class=\"fusion-text fusion-text-3\" style=\"font-size:11px;transform:translate3d(0,0,0);\"><p>Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HADEA). Neither the European Union nor the granting authority can be held responsible for them<\/p>\n<\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:66.666666666667% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.88%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.88%;}@media only screen and (max-width:1532px) {.fusion-body .fusion-builder-column-0{width:66.666666666667% !important;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 2.88%;margin-left : 2.88%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-0{width:100% !important;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_3 1_3 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-color:#f9f9f9;border-width: 0 0 0 2px;border-color:#9DA0D2;border-style:solid;box-shadow:0px 0px ;;padding: 4% 4% 4% 4%;\"><div class=\"fusion-text fusion-text-4\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">PROGRAMME<\/h5>\n<p style=\"text-align: center;\">HORIZON Health<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:10px;margin-bottom:10px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#9DA0D2;border-top-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-5\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">PRINCIPAL\u00a0INVESTIGATOR<\/h5>\n<p style=\"text-align: center;\">Dr. Julio N\u00fa\u00f1ez Villota<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:10px;margin-bottom:10px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#9DA0D2;border-top-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-6\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">ROLE<\/h5>\n<p style=\"text-align: center;\">PARTNERS<\/p>\n<\/div><div class=\"fusion-text fusion-text-7\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">FUNDING<\/h5>\n<p style=\"text-align: center;\">\u20ac 282,625<\/p>\n<\/div><div class=\"fusion-text fusion-text-8\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">START\/END<\/h5>\n<p style=\"text-align: center;\">2023-2028<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:10px;margin-bottom:10px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#9DA0D2;border-top-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-9\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">WEB<\/h5>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.biotool-chf.eu\/\" target=\"_blank\" rel=\"noopener\">www.biotool-chf.eu<\/a><\/p>\n<\/div><div class=\"fusion-text fusion-text-10\" style=\"transform:translate3d(0,0,0);\"><h5 style=\"text-align: center;\">SOCIAL MEDIA<\/h5>\n<\/div><div class=\"fusion-social-links\" style=\"text-align:center\"><div class=\"fusion-social-networks\"><div class=\"fusion-social-networks-wrapper\"><a class=\"fusion-social-network-icon fusion-tooltip fusion-twitter fusion-icon-twitter\" style=\"color:#9ea0a4;font-size:16px;\" data-placement=\"top\" data-title=\"Twitter\" data-toggle=\"tooltip\" title=\"Twitter\" aria-label=\"twitter\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/twitter.com\/BiotoolChf\"><\/a><a class=\"fusion-social-network-icon fusion-tooltip fusion-linkedin fusion-icon-linkedin\" style=\"color:#9ea0a4;font-size:16px;\" data-placement=\"top\" data-title=\"LinkedIn\" data-toggle=\"tooltip\" title=\"LinkedIn\" aria-label=\"linkedin\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.linkedin.com\/company\/101345426\/\"><\/a><\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 4% !important;padding-right : 4% !important;margin-right : 5.76%;padding-bottom : 4% !important;padding-left : 4% !important;margin-left : 5.76%;}@media only 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0px;}<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":10,"featured_media":0,"parent":8474,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/pages\/37167"}],"collection":[{"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/comments?post=37167"}],"version-history":[{"count":4,"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/pages\/37167\/revisions"}],"predecessor-version":[{"id":37174,"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/pages\/37167\/revisions\/37174"}],"up":[{"embeddable":true,"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/pages\/8474"}],"wp:attachment":[{"href":"https:\/\/www.incliva.es\/en\/wp-json\/wp\/v2\/media?parent=37167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}