Research Group on the Study of Cardiovascular Risk in Children and Adolescents

Cardiovascular Area

The iPEDITEC Unit brings healthcare workers into daily contact with engineers developing software for signal capture through mobile devices. Studying the psychological parameters that facilitate personalized therapy has been a priority aim during 2021, resulting in improved treatment of obese pediatric patients in the Unit

– The PAIDO Program is focused on personalized medical care extended through initiatives involving family, educators, nutritionists, physical education teachers and other social agents. Treatment goes beyond the hospital setting to include the child´s environment and personal sphere and is supported by state-of the art artificial intelligence technologies

– To improve the knowledge of fetal life and postnatal growth on the development of cardiometabolic risk factors early in life. The KITE cohort is a prospective study starting at birth and assessing the determinants of cardiometabolic risk factors in the first decades of life. Omics data from umbilical cord are available and the analysis of the interaction between clinical data and omics may help to introduce actions in critical periods of life and the potential contribution to reduce cardiometabolic disease later in life. Dr. Lurbe is the coordinator of the new document of the European Guidelines on Arterial Hypertension in Children and Adolescents

Coordinator
Dra. Empar Lurbe i Ferrer
empar.lurbe@uv.es/malurfe@uv.es
RESEARCHERS
Leading, R4

Empar Lurbe i Ferrer    

Established, R3

Francisco Aguilar Bacallado
Isabel Torró Doménech

Recognised/Emerging, R2

Julio Álvarez Pitti

First Stage, R1

Ana de Blas Zapata
Nuria García Carbonell
Rafael Gómez Zafra

STAFF
Collaborating Researchers

Juan José Alcón Sáez

Nurse
Technicians

Francisco Ponce Zanón

Administrative assistant

Christine Deutsch

Publications
2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement. Stergiou GS, Palatini P, Parati G, O’Brien E, Januszewicz A, Lurbe E, Persu A, Mancia G, Kreutz R. Journal of Hypertension. 2021 Jul 1;39(7):1293-1302. doi: 10.1097/HJH.0000000000002843. PMID: 33710173

Developmental and early life origins of cardiometabolic risk factors: novel findings and implications. Lurbe E, Ingelfinger J. Hypertension. 2021 Feb;77(2):308-318. doi: 10.1161/HYPERTENSIONAHA.120.14592. PMID: 33390043

Early symptomatic congenital syphilis in a newborn. Ordono Saiz M, Chacon Flocos S, Rodriguez-Ramos M, Gomez Zafra R. Anales de Pediatría. 2021 May;94(5):341-342. doi: 10.1016/j.anpedi.2020.05.012. PMID: 32620318

European Network for blood pressure research in children and adolescents (COST Action CA 19115). Lurbe E, Fernandez-Aranda F, Wuhl E, en representacion del Consorcio HyperChildNET. Anales de Pediatria. 2021 Jun;94(6):421.e1-421.e4. doi: 10.1016/j.anpedi.2021.01.015. PMID: 33653658

European Network for blood pressure research in children and adolescents (COST Action CA 19115). Lurbe E, Fernandez-Aranda F, Wuhl E, HyperChildNET Consortium. Anales de Pediatria. 2021 Jun;94(6):421.e1-421.e4. doi: 10.1016/j.anpede.2021.01.003. PMID: 34090641

Lifestyle, psychological, socioeconomic and environmental factors and their impact on hypertension during the coronavirus disease 2019 pandemic. Kreutz R, Dobrowolski P, Prejbisz A, Algharably EAEH, Bilo G, Creutzig F, Grassi G, Kotsis V, Lovic D, Lurbe E, Modesti PA, Pappaccogli M, Parati G, Persu A, Polonia J, Rajzer M, de Timary P, Weber T, Weisser B, Tsioufis K, Mancia G, Januszewicz A. Journal of Hypertension. 2021 Jun 1;39(6):1077-1089. doi: 10.1097/HJH.0000000000002770. PMID: 33395152

Obesity and cardiometabolic risk factors: from childhood to adulthood. Drozdz D, Alvarez-Pitti J, Wojcik M, Borghi C, Gabbianelli R, Mazur A, Herceg-Cavrak V, Gonzalez Lopez-Valcarcel B, Brzezinski M, Lurbe E, Wuehl E. Nutrients. 2021 Nov 22;13(11):4176. doi: 10.3390/nu13114176. PMID: 34836431

Obesity and eating disorders in children and adolescents: the bidirectional link. Stabouli S, Erdine S, Suurorg L, Jankauskiene A, Lurbe E. Nutrients. 2021 Nov 29;13(12):4321. doi: 10.3390/nu13124321. PMID: 34959873

Primary hypertension beginning in childhood and risk for future cardiovascular disease. Falkner B, Lurbe E. Journal of Pediatrics. 2021 Nov;238:16-25. doi: 10.1016/j.jpeds.2021.08.008. PMID: 34391765

Scientific mapping of the research output on hypertension in children and adolescents, 2010-2018. Abad-Garcia MF, Gonzalez-Teruel A, Bolanos-Pizarro M, Lurbe I Ferrer E. Journal of Hypertension. 2021 Jun 1;39(6):1070-1076. doi: 10.1097/HJH.0000000000002772. PMID: 33929402

The USPSTF call to inaction on blood pressure screening in children and adolescents. Falkner B, Lurbe E. Pediatric Nephrology. 2021 Jun;36(6):1327-1329. doi: 10.1007/s00467-021-04926-y. PMID: 33449211

Exercise as medicine in chronic diseases during childhood and adolescence. Alvarez Pitti J, Casajus Mallen J, Leis Trabazo R, Lucia A, Lopez de Lara D, Moreno Aznar L, Rodriguez Martinez G. Anales de Pediatria. 2020 Mar;92(3):173.e1-173.e8. doi: 10.1016/j.anpedi.2020.01.010. PMID: 32061527

Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease. Borghi C, Agabiti-Rosei E, Johnson R, Kielstein J, Lurbe Ferrer E, Mancia G, Redón Mas J, Stack A, Tsioufis K. European Journal of Internal Medicine. 2020 Oct;80:1-11. doi: 10.1016/j.ejim.2020.07.006. PMID: 32739239

Identifying poor cardiorespiratory fitness in overweight and obese children and adolescents by using heart rate variability analysis under resting conditions. Redon Lurbe P, Grassi G, Redón Mas J, Alvarez Pitti J, Lurbe Ferrer E. Blood Pressure. 2020 Feb;29(1):13-20. doi: 10.1080/08037051.2019.1700777. PMID: 31829032

Innovations in Infant Feeding: Future Challenges and Opportunities in Obesity and Cardiometabolic Disease. Alvarez Pitti J, De Blas A, Lurbe Ferrer E. Nutrients. 2020 Nov 14;12(11):3508. doi: 10.3390/nu12113508. PMID: 33202614

Network for blood pressure research in children and adolescents: A Cost Action. Lurbe E, HyperChild NET Network. Journal of Hypertension. 2020 Nov;38(11):2331-2334. doi: 10.1097/HJH.0000000000002639. PMID: 32941203

Nutraceuticals and blood pressure control: a European Society of Hypertension position document. Borghi C, Tsioufis K, Agabiti-Rosei E, Burnier M, Cicero A, Clement D, Coca A, Desideri G, Grassi G, Lovic D, LURBE FERRER E, Kahan T, Kreutz R, Jelakovic B, Polonia J, Redón Mas J, Van De Borne P, Mancia G. Journal of Hypertension. 2020 May;38(5):799-812. doi: 10.1097/HJH.0000000000002353. PMID: 31977574

Primordial Prevention of High Blood Pressure in Childhood An Opportunity Not to be Missed. Falkner B, Lurbe Ferrer E. Hypertension. 2020 May;75(5):1142-1150. doi: 10.1161/HYPERTENSIONAHA.119.14059. PMID: 32223379

Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513

Projects
Referencia: PI20/00269
Título: Impacto del peso al nacer y el patrón de crecimiento en factores de riesgo cardiometabólico en adolescentes postpuberales: aproximación clínica y molecular
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Empar Lurbe i Ferrer
Duración: 2021 – 2023
Presupuesto: 174.845 €

Referencia: COST CA19115
Título: Network for blood pressure research in children and adolescents. HyperChildNET
Entidad Financiadora: European Commision
Investigador principal: Empar Lurbe i Ferrer
Duración: 2020 – 2024
Presupuesto: 700.000 €

Referencia: UNICEF-LAB-COVID
Título: Esc@la Salut del Programa de Atención Integral de la Obesidad Infantil (PAIDO)
Entidad Financiadora: UNICEF
Investigador principal: Julio Álvarez Pitti
Duración: 2020 – 2020
Presupuesto: no hay

Referencia: PI17/01517
Título: Programación fetal y desarrollo postnatal en hijos de madres obesas: modulación por la alimentación en el primer año de vida
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Empar Lurbe i Ferrer
Duración: 2018 – 2021
Presupuesto: 170.005 €

Referencia: CB06/03/0039
Título: CIBER de la Obesidad y Nutrición (CIBERobn)
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Empar Lurbe i Ferrer
Duración: 2006 –
Presupuesto: 85.000 €

+ Information

2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement. Stergiou GS, Palatini P, Parati G, O’Brien E, Januszewicz A, Lurbe E, Persu A, Mancia G, Kreutz R. Journal of Hypertension. 2021 Jul 1;39(7):1293-1302. doi: 10.1097/HJH.0000000000002843. PMID: 33710173

Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513

2018 ESC/ESH Guidelines for the management of arterial. Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I. Kardiologia Polska. 2019;77(2):71-159. doi: 10.5603/KP.2019.0018. PMID: 30816983

Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. Lurbe E, Torró I, Álvarez J, Aguilar F, Mancia G, Redon J, Redon P. Journal of Hypertension. 2019 Dec;37(12):2414-2421. doi: 10.1097/HJH.0000000000002229. PMID: 31688292