Área Metabolismo

Grupo de Investigación en Psiquiatría y Enfermedades Neurodegenerativas

Julio Sanjuán Arias

El Dr. Sanjuán es Profesor Titular de Psiquiatría de la Facultad de Medicina de Valencia. Responsable de la Unidad de primeros Episodios Psicóticos del Hospital Clínico de Valencia. Miembro correspondiente de la Real Academia de Medicina de Valencia. Responsable Nacional del Programa de Investigación en Esquizofrenia del CIBERSAM. Ha publicado más de 100 artículos en revistas indexadas, 52 capítulos de libros y  ha sido el editor de 5 libros. 

 

Grupo de Investigación en Psiquiatría y Enfermedades Neurodegenerativas

Investigador colaborador

Eduardo Jesús Aguilar García-Iturrospe
Esther Lorente Rovira
Francisco Olucha Bordonau
Gracián García Martí
José Carlos González Piqueras
Juan Nacher Roselló
Manuel Jover Martínez
Maria Dolores Moltó Ruiz
Maria José Escarti Fabra
Marien Gadea Domenech

Investigador predoctoral

Javier Gilabert Juan
Jose Luis Ivorra Martínez
  • Perfeccionamiento de pagina web y creación de un sistema intranet para mejorar la adherencia de los primeros episodios psicóticos.
  • Ampliación de base de datos común para estudios multicentricos (CIBERSAM).
  • Desarrollo de nuevas técnicas multimodales EEG-fMRI para la identificación de las alucinaciones en la psicosis.
  • Desarrollo de modelos animales en Trastorno mental Grave y enfermedades neurodegenerativas.
  • Eficacia de Terapia Cognitiva en alucinaciones persistentes en psicosis.
  • Estudio de Polimorfismos de Riesgo en Trastorno mental Grave.
  • Modelos de predicción y tratamiento en primeros episodios psicóticos.
Número total de publicaciones: 98. Factor de Impacto acumulado: 357.25
Neurochemical Phenotype of Reelin Immunoreactive Cells in the Piriform Cortex Layer II.
Carceller H, Rovira-Esteban L, Nacher J, Castrén E, Guirado R
Frontiers in cellular neuroscience. 2016. 65. FI: 4.289
Neuroligin-2 Expression in the Prefrontal Cortex is Involved in Attention Deficits Induced by Peripubertal Stress.
Tzanoulinou S, García-Mompó C, Riccio O, Grosse J, Zanoletti O, Dedousis P, Nacher J, Sandi C
Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology.. 2016 Feb. 751-61. FI: 7.048
Polysialic Acid Acute Depletion Induces Structural Plasticity in Interneurons and Impairs the Excitation/Inhibition Balance in Medial Prefrontal Cortex Organotypic Cultures.
Castillo-Gómez E, Pérez-Rando M, Vidueira S, Nacher J
Frontiers in cellular neuroscience. 2016 Jun 29. 170. FI: 4.609
Pharmacogenetic study of antipsychotic induced acute extrapyramidal symptoms in a first episode psychosis cohort: role of dopamine, serotonin and glutamate candidate genes.
Mas S, Gassó P, Lafuente A, Bioque M, Lobo A, Gonzàlez-Pinto A, Olmeda MS, Corripio I, Llerena A, Cabrera B, Saiz-Ruiz J, Bernardo M, PEPs GROUP.
The pharmacogenomics journal.. 2016 Oct. 439-45. FI: 3.784
Is Hypoesthesia of the Malleolus a Subtle Neurological Sign in Anxiety?
Livianos L, García-Blanco AC, Civera M, González-Valls PI, Echevarría H, García-Moncho JM, Cardozo JC, Castell R, Jávega C, Matamoros JM, Rubio G, Rojo-Moreno L
The Journal of neuropsychiatry and clinical neurosciences.. 2016 Jan 21. appineuropsych15080202. FI: 2.817
Letter to the editor concerning "A new approach to corpus callosum anomalies in idiopathic scoliosis using diffusion tensor magnetic resonance imaging" by Joly O et al. (2014) Eur Spine J 23:2643-9.
Domenech J, Marti-Bonmati L, Alberich-Bayarri A, Garcia-Martí G
European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society.. 2016 Apr. 1289-90. FI: 2.066
Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease.
Soriano S, Calap-Quintana P, Llorens JV, Al-Ramahi I, Gutiérrez L, Martínez-Sebastián MJ, Botas J, Moltó MD
PLoS hub for clinical trials. 2016. e0159209. FI: 3.057
Testing the Benefits of Neurofeedback on Selective Attention Measured Through Dichotic Listening.
Gadea M, Aliño M, Garijo E, Espert R, Salvador A
Applied psychophysiology and biofeedback.. 2016 Jun. 157-64. FI: 1.847
Coping strategies for postpartum depression: a multi-centric study of 1626 women.
Gutiérrez-Zotes A, Labad J, Martín-Santos R, García-Esteve L, Gelabert E, Jover M, Guillamat R, Mayoral F, Gornemann I, Canellas F, Gratacós M, Guitart M, Roca M, Costas J, Ivorra JL, Navinés R, de Diego-Otero Y, Vilella E, Sanjuan J
Archives of women's mental health.. 2016 Jun. 455-61. FI: 2.164
Effectiveness, efficiency and efficacy in the treatment of schizophrenia multidimensional: Rethinking project.
Crespo-Facorro B, Bernardo M, Argimon JM, Arrojo M, Bravo-Ortiz MF, Cabrera-Cifuentes A, Carretero-Román J, Franco-Martín MA, García-Portilla P, Haro JM, Olivares JM, Penadés R, Del Pino-Montes J, Sanjuán J, Arango C
Revista de psiquiatría y salud mental.. 2016 Oct 22. . FI: 1.65
Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats.
Castillo-Gómez E, Varea E, Blasco-Ibáñez JM, Crespo C, Nacher J
Neural plasticity.. 2016. 1615363. FI: 3.582
Effects of PSA Removal from NCAM on the Critical Period Plasticity Triggered by the Antidepressant Fluoxetine in the Visual Cortex.
Guirado R, La Terra D, Bourguignon M, Carceller H, Umemori J, Sipilä P, Nacher J, Castrén E
Frontiers in cellular neuroscience. 2016. 22. FI: 4.289
Characterization and isolation of immature neurons of the adult mouse piriform cortex.
Rubio A, Belles M, Belenguer G, Vidueira S, Fariñas I, Nacher J
Developmental neurobiology.. 2016 Jul. 748-63. FI: 3.37
Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis.
López-Hidalgo R, Ballestín R, Vega J, Blasco-Ibáñez JM, Crespo C, Gilabert-Juan J, Nácher J, Varea E
Frontiers in neuroscience. 2016 Mar 2. 75
A Pharmacovigilance Study in First Episode of Psychosis: Psychopharmacological Interventions and Safety Profiles in the PEPs Project.
Bioque M, Llerena A, Cabrera B, Mezquida G, Lobo A, González-Pinto A, Díaz-Caneja CM, Corripio I, Aguilar EJ, Bulbena A, Castro-Fornieles J, Vieta E, Lafuente A, Mas S, Parellada M, Saiz-Ruiz J, Cuesta MJ, Bernardo M, PEPs GROUP
The international journal of neuropsychopharmacology. 2016 Apr. . FI: 4.009
Age at First Episode Modulates Diagnosis-Related Structural Brain Abnormalities in Psychosis.
Pina-Camacho L, Del Rey-Mejías Á, Janssen J, Bioque M, González-Pinto A, Arango C, Lobo A, Sarró S, Desco M, Sanjuan J, Lacalle-Aurioles M, Cuesta MJ, Saiz-Ruiz J, Bernardo M, Parellada M, PEPs Group
Schizophrenia bulletin.. 2016 Mar. 344-57. FI: 8.449999999999999
Acoustic radiation force impulse imaging elastography is efficacious in detecting hepatic fibrosis in children.
Picó Aliaga SD, Muro Velilla D, García-Martí G, Sangüesa Nebot C, Martí-Bonmatí L
Radiologia. 2015 Jul-Aug. 314-320
Acute oral administration of low doses of methylphenidate targets calretinin neurons in the rat septal area.
García-Avilés Á, Albert-Gascó H, Arnal-Vicente I, Elhajj E, Sanjuan-Arias J, Sanchez-Perez AM, Olucha-Bordonau F
Frontiers in neuroanatomy. 2015. 33. FI: 3.544
Altered Distribution of Hippocampal Interneurons in the Murine Down Syndrome Model Ts65Dn.
Hernández-González S, Ballestín R, López-Hidalgo R, Gilabert-Juan J, Blasco-Ibáñez JM, Crespo C, Nácher J, Varea E
Neurochemical research. 2015 Jan. 151-64. FI: 2.593
Automatic individual arterial input functions calculated from PCA outperform manual and population-averaged approaches for the pharmacokinetic modeling of DCE-MR images.
Sanz-Requena R, Prats-Montalbán JM, Martí-Bonmatí L, Alberich-Bayarri Á, García-Martí G, Pérez R, Ferrer A
Journal of magnetic resonance imaging : JMRI. 2015 Aug. 477-87. FI: 3.21
Building up careers in translational neuroscience and mental health research: Education and training in the Centre for Biomedical Research in Mental Health.
Rapado-Castro M, Pazos Á, Fañanás L, Bernardo M, Ayuso-Mateos JL, Leza JC, Berrocoso E, de Arriba J, Roldán L, Sanjuán J, Pérez V, Haro JM, Palomo T, Valdizan EM, Micó JA, Sánchez M, Arango C
Revista de psiquiatria y salud mental. 2015 Apr-Jun. 65-74. FI: 1.622
Characterization and isolation of immature neurons of the adult mouse piriform cortex.
Rubio A, Belles M, Belenguer G, Vidueira S, Fariñas I, Nacher J
Developmental neurobiology.. 2015 Oct 21. . FI: 3.37
Chronic benzodiazepine treatment decreases spine density in cortical pyramidal neurons.
Curto Y, Garcia-Mompo C, Bueno-Fernandez C, Nacher J
Neuroscience letters.. 2015 Dec 28. 41-46. FI: 2.03
Coping strategies and postpartum depressive symptoms: A structural equation modelling approach.
Gutiérrez-Zotes A, Labad J, Martín-Santos R, García-Esteve L, Gelabert E, Jover M, Guillamat R, Mayoral F, Gornemann I, Canellas F, Gratacós M, Guitart M, Roca M, Costas J, Luis Ivorra J, Navinés R, de Diego-Otero Y, Vilella E, Sanjuan J
European psychiatry : the journal of the Association of European Psychiatrists.. 2015 Sep. 701-8. FI: 3.439
Deceit and facial expression in children: the enabling role of the "poker face" child and the dependent personality of the detector.
Gadea M, Aliño M, Espert R, Salvador A
Frontiers in psychology. 2015. 1089. FI: 2.56
Familial liability to schizophrenia and mood disorders and cognitive impairment in psychosis.
Cuesta MJ, Zarzuela A, Sánchez-Torres AM, Lorente-Omeñaca R, Moreno-Izco L, Sanjuán J, Peralta V
Psychiatry research.. 2015 Jun 30. 258-64. FI: 2.467
Involuntary outpatient treatment (IOT) in Spain.
Hernández-Viadel M, Cañete-Nicolás C, Bellido-Rodriguez C, Asensio-Pascual P, Lera-Calatayud G, Calabuig-Crespo R, Leal-Cercós C
International journal of law and psychiatry.. 2015 Jul-Aug. 42460. FI: 0.9340000000000001
New neurons from old beliefs in the adult piriform cortex? A Commentary on: "Occurrence of new neurons in the piriform cortex".
Nacher J, Bonfanti L
Frontiers in neuroanatomy. 2015. 62. FI: 3.544
Premorbid adjustment and clinical correlates of cognitive impairment in first-episode psychosis. The PEPsCog Study.
Cuesta MJ, Sánchez-Torres AM, Cabrera B, Bioque M, Merchán-Naranjo J, Corripio I, González-Pinto A, Lobo A, Bombín I, de la Serna E, Sanjuan J, Parellada M, Saiz-Ruiz J, Bernardo M, PEPs Group
Schizophrenia research.. 2015 May. 65-73. FI: 3.923
Semaphorin and plexin gene expression is altered in the prefrontal cortex of schizophrenia patients with and without auditory hallucinations.
Gilabert-Juan J, Sáez AR, Lopez-Campos G, Sebastiá-Ortega N, González-Martínez R, Costa J, Haro JM, Callado LF, Meana JJ, Nacher J, Sanjuán J, Moltó MD
Psychiatry research.. 2015 Oct 30. 850-7. FI: 2.467
Septal projections to nucleus incertus in the rat: Bidirectional pathways for modulation of hippocampal function.
Sánchez-Pérez AM, Arnal-Vicente I, Santos FN, Pereira CW, ElMlili N, Sanjuan J, Ma S, Gundlach AL, Olucha-Bordonau FE
The Journal of comparative neurology. 2015 Mar 1. 565-88. FI: 3.225
Streptozotocin diabetic mice display depressive-like behavior and alterations in the structure, neurotransmission and plasticity of medial prefrontal cortex interneurons.
Castillo-Gómez E, Coviello S, Perez-Rando M, Curto Y, Carceller H, Salvador A, Nacher J
Brain research bulletin. 2015 Jun 22. 45-56. FI: 2.718
Synaptic connectivity of the cholinergic axons in the olfactory bulb of the cynomolgus monkey.
Liberia T, Blasco-Ibáñez JM, Nácher J, Varea E, Lanciego JL, Crespo C
Frontiers in neuroanatomy. 2015. 28. FI: 3.544
TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich's Ataxia.
Calap-Quintana P, Soriano S, Llorens JV, Al-Ramahi I, Botas J, Moltó MD, Martínez-Sebastián MJ
PloS one. 2015. e0132376. FI: 3.234
Using gene expression and systems biology to interrogate auditory hallucinations in schizophrenic patients.
Lopez-Campos G, Gilabert-Juan J, Sebastia-Ortega N, Gonzalez-Martinez R, Nacher J, Sanjuan J, Molto MD
Studies in health technology and informatics. 2015. 950
Abnormal synchrony and effective connectivity in patients with schizophrenia and auditory hallucinations.
de la Iglesia-Vaya M, Escartí MJ, Molina-Mateo J, Martí-Bonmatí L, Gadea M, Castellanos FX, Aguilar García-Iturrospe EJ, Robles M, Biswal BB, Sanjuan J
NeuroImage. Clinical. 2014. 171-9
Astrocytes of the murine model for Down Syndrome Ts65Dn display reduced intracellular ionic zinc.
Ballestín R, Blasco-Ibáñez JM, Crespo C, Nacher J, López-Hidalgo R, Gilabert-Juan J, Moltó D, Varea E
Neurochemistry international. 2014 Jun 6. 48-53. FI: 2.65
Chronic fluoxetine treatment alters the structure, connectivity and plasticity of cortical interneurons.
Guirado R, Perez-Rando M, Sanchez-Matarredona D, Castrén E, Nacher J
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2014 Oct. 1635-46. FI: 5.264
Common variant at 16p11.2 conferring risk of psychosis.
Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T, Ingason A, Pirinen M, Strengman E, GROUP, Hougaard DM, Orntoft T, Didriksen M, Hollegaard MV, Nordentoft M, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Etain B, Bellivier F, Méary A, Schürhoff F, Szoke A, Ribolsi M, Magni V, Siracusano A, Sperling S, Rossner M, Christiansen C, Kiemeney LA, Franke B, van den Berg LH, Veldink J, Curran S, Bolton P, Poot M, Staal W, Rehnstrom K, Kilpinen H, Freitag CM, Meyer J, Magnusson P, Saemundsen E, Martsenkovsky I, Bikshaieva I, Martsenkovska I, Vashchenko O, Raleva M, Paketchieva K, Stefanovski B, Durmishi N, Pejovic Milovancevic M, Lecic Tosevski D, Silagadze T, Naneishvili N, Mikeladze N, Surguladze S, Vincent JB, Farmer A, Mitchell PB, Wright A, Schofield PR, Fullerton JM, Montgomery GW, Martin NG, Rubino IA, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Terenius L, Jönsson EG, Bakker S, van Os J, Jablensky A, Leboyer M, Bramon E, Powell J, Murray R, Corvin A, Gill M, Morris D, O'Neill FA, Kendler K, Riley B, Wellcome Trust Case Control Consortium 2, Craddock N, Owen MJ, O'Donovan MC, Thorsteinsdottir U, Kong A, Ehrenreich H, Carracedo A, Golimbet V, Andreassen OA, Børglum AD, Mors O, Mortensen PB, Werge T, Ophoff RA, Nöthen MM, Rietschel M, Cichon S, Ruggeri M, Tosato S, Palotie A, St Clair D, Rujescu D, Collier DA, Stefansson H, Stefansson K
Molecular psychiatry. 2014 Jan. 108-14. FI: 15.147
Deletion of ?-neurexin II results in autism-related behaviors in mice.
Dachtler J, Glasper J, Cohen RN, Ivorra JL, Swiffen DJ, Jackson AJ, Harte MK, Rodgers RJ, Clapcote SJ
Translational psychiatry. 2014 Nov 25. e484. FI: 4.36
Double-blind, placebo-controlled study of the efficacy of reboxetine and citalopram as adjuncts to atypical antipsychotics for negative symptoms of schizophrenia.
Usall J, López-Carrilero R, Iniesta R, Roca M, Caballero M, Rodriguez-Jimenez R, Oliveira C, Bernardo M, Corripio I, Sindreu SD, González Piqueras JC, Felipe AE, Fernandez de Corres B, Ibáñez A, Huerta R, Abordaje Síntomas Negativos Esquizofrenia Group
The Journal of clinical psychiatry. 2014 Jun. 608-15. FI: 5.139
Gray-white matter and cerebrospinal fluid volume differences in children with Specific Language Impairment and/or Reading Disability.
Girbau-Massana D, Garcia-Marti G, Marti-Bonmati L, Schwartz RG
Neuropsychologia. 2014 Apr. 90-100. FI: 3.451
Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.
European Network of National Networks studying Gene-Environment Interactions in Schizophrenia (EU-GEI), van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, Gayer-Anderson C, Hubbard K, Beards S, Stilo SA, Onyejiaka A, Bourque F, Modinos G, Tognin S, Calem M, O'Donovan MC, Owen MJ, Holmans P, Williams N, Craddock N, Richards A, Humphreys I, Meyer-Lindenberg A, Leweke FM, Tost H, Akdeniz C, Rohleder C, Bumb JM, Schwarz E, Alptekin K, Üçok A, Saka MC, Atba?o?lu EC, Gülöksüz S, Gumus-Akay G, Cihan B, Karada? H, Soygür H, Cankurtaran E?, Ulusoy S, Akdede B, Binbay T, Ayer A, Noyan H, Karaday? G, Akturan E, Ula? H, Arango C, Parellada M, Bernardo M, Sanjuán J, Bobes J, Arrojo M, Santos JL, Cuadrado P, Rodríguez Solano JJ, Carracedo A, García Bernardo E, Roldán L, López G, Cabrera B, Cruz S, Díaz Mesa EM, Pouso M, Jiménez E, Sánchez T, Rapado M, González E, Martínez C, Sánchez E, Olmeda MS, de Haan L, Velthorst E, van der Gaag M, Selten JP, van Dam D, van der Ven E, van der Meer F, Messchaert E, Kraan T, Burger N, Leboyer M, Szoke A, Schürhoff F, Llorca PM, Jamain S, Tortelli A, Frijda F, Vilain J, Galliot AM, Baudin G, Ferchiou A, Richard JR, Bulzacka E, Charpeaud T, Tronche AM, De Hert M, van Winkel R, Decoster J, Derom C, Thiery E, Stefanis NC, Sachs G, Aschauer H, Lasser I, Winklbaur B, Schlögelhofer M, Riecher-Rössler A, Borgwardt S, Walter A, Harrisberger F, Smieskova R, Rapp C, Ittig S, Soguel-dit-Piquard F, Studerus E, Klosterkötter J, Ruhrmann S, Paruch J, Julkowski D, Hilboll D, Sham PC, Cherny SS, Chen EY, Campbell DD, Li M, Romeo-Casabona CM, Emaldi Cirión A, Urruela Mora A, Jones P, Kirkbride J, Cannon M, Rujescu D, Tarricone I, Berardi D, Bonora E, Seri M, Marcacci T, Chiri L, Chierzi F, Storbini V, Braca M, Minenna MG, Donegani I, Fioritti A, La Barbera D, La Cascia CE, Mulè A, Sideli L, Sartorio R, Ferraro L, Tripoli G, Seminerio F, Marinaro AM, McGorry P, Nelson B, Amminger GP, Pantelis C, Menezes PR, Del-Ben CM, Gallo Tenan SH, Shuhama R, Ruggeri M, Tosato S, Lasalvia A, Bonetto C, Ira E, Nordentoft M, Krebs MO, Barrantes-Vidal N, Cristóbal P, Kwapil TR, Brietzke E, Bressan RA, Gadelha A, Maric NP, Andric S, Mihaljevic M, Mirjanic T
Schizophrenia bulletin. 2014 Jul. 729-36. FI: 8.606999999999999
Impaired Hippocampal Neuroligin-2 Function by Chronic Stress or Synthetic Peptide Treatment is Linked to Social Deficits and Increased Aggression.
van der Kooij MA, Fantin M, Kraev I, Korshunova I, Grosse J, Zanoletti O, Guirado R, Garcia-Mompó C, Nacher J, Stewart MG, Berezin V, Sandi C
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2014 Apr. 1148-58. FI: 7.833
Involuntary outpatient treatment in patients with severe mental illness: a one-year follow-up study.
Lera-Calatayud G, Hernández-Viadel M, Bellido-Rodriguez C, Cañete-Nicolás C, Asensio-Pascual P, Calabuig-Crespo R, Leal-Cercós C
International journal of law and psychiatry. 2014 May-Jun. 267-71. FI: 0.846
Long-term behavioral programming induced by peripuberty stress in rats is accompanied by GABAergic-related alterations in the Amygdala.
Tzanoulinou S, García-Mompó C, Castillo-Gómez E, Veenit V, Nacher J, Sandi C
PloS one. 2014. e94666. FI: 3.534
Maternal anxiety following delivery, early infant temperament and mother's confidence in caregiving.
Jover M, Colomer J, Carot JM, Larsson C, Bobes MT, Ivorra JL, Martín-Brufau R, Sanjuan J
The Spanish journal of psychology. 2014 Dec 22. E95. FI: 0.706
Pharmacogenetic study of second-generation antipsychotic long-term treatment metabolic side effects (the SLiM Study): Rationale, objectives, design and sample description.
Pina-Camacho L, Díaz-Caneja CM, Saiz PA, Bobes J, Corripio I, Grasa E, Rodriguez-Jimenez R, Fernández M, Sanjuán J, García-López A, Tapia-Casellas C, Alvarez-Blázquez M, Fraguas D, Mitjans M, Arias B, Arango C
Revista de psiquiatrí?a y salud mental. 2014 October - December. 166-178. FI: 1.044
Quantitative phase-contrast MRI study of cerebrospinal fluid flow: A method for identifying patients with normal-pressure hydrocephalus.
Forner Giner J, Sanz-Requena R, Flórez N, Alberich-Bayarri A, García-Martí G, Ponz A, Martí-Bonmatí L
Neurología (Barcelona, Spain). 2014 Mar. 68-75. FI: 1.352
Replication of previous genome-wide association studies of psychiatric diseases in a large schizophrenia case-control sample from Spain.
Ivorra JL, Rivero O, Costas J, Iniesta R, Arrojo M, Ramos-Ríos R, Carracedo A, Palomo T, Rodriguez-Jimenez R, Cervilla J, Gutiérrez B, Molina E, Arango C, Alvarez M, Pascual JC, Pérez V, Saiz PA, García-Portilla MP, Bobes J, González-Pinto A, Zorrilla I, Haro JM, Bernardo M, Baca-García E, González JC, Hoenicka J, Moltó MD, Sanjuán J
Schizophrenia research. 2014 Oct. 107-13. FI: 4.426
Reproducibility and accuracy in the morphometric and mechanical quantification of trabecular bone from 3 Tesla magnetic resonance images.
Alberich-Bayarri A, Martí-Bonmatí L, Sanz-Requena R, Sánchez-González J, Hervás Briz V, García-Martí G, Pérez MA
Radiología. 2014 January - February. 27-34
Study of the inferior colliculus in patients with schizophrenia by magnetic resonance spectroscopy.
Martinez-Granados B, Martinez-Bisbal MC, Sanjuan J, Aguilar EJ, Marti-Bonmati L, Molla E, Celda B
Revista de neurologia. 2014 Jul 1. 42186. FI: 0.926
The Dendritic Spines of Interneurons Are Dynamic Structures Influenced by PSA-NCAM Expression.
Guirado R, Perez-Rando M, Sanchez-Matarredona D, Castillo-Gómez E, Liberia T, Rovira-Esteban L, Varea E, Crespo C, Blasco-Ibáñez JM, Nacher J
Cerebral cortex (New York, N.Y. : 1991). 2014 Nov. 3014-24. FI: 8.305
The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: Further evidence and meta-analysis.
Weber H, Klamer D, Freudenberg F, Kittel-Schneider S, Rivero O, Scholz CJ, Volkert J, Kopf J, Heupel J, Herterich S, Adolfsson R, Alttoa A, Post A, Grußendorf H, Kramer A, Gessner A, Schmidt B, Hempel S, Jacob CP, Sanjuán J, Moltó MD, Lesch KP, Freitag CM, Kent L, Reif A
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2014 Jan. 65-85. FI: 5.395
Towards a framework for treatment effectiveness in schizophrenia.
Juckel G, de Bartolomeis A, Gorwood P, Mosolov S, Pani L, Rossi A, Sanjuan J
Neuropsychiatric disease and treatment. 2014. 1867-78. FI: 2.154
[Dyslipemia in diabetics treated with statins. Results of the DYSIS study in Spian].
Millán J, Alegría E, Guijarro C, Lozano JV, Vitale GC, González-Timón B, González-Juanatey JR
Medicina clínica. 2013 Nov 16. 430-6. FI: 1.399
A "double hit" murine model for schizophrenia shows alterations in the structure and neurochemistry of the medial prefrontal cortex and the hippocampus.
Gilabert-Juan J, Belles M, Saez AR, Carceller H, Zamarbide-Fores S, Moltó MD, Nacher J
Neurobiology of disease. 2013 Nov. 126-40. FI: 5.624
[Hipogonadism. Global epidemiology and transversal relationships].
Martinez-Jabaloyas JM
Archivos españoles de urología. 2013 Sep. 632-8
Arterial and Venous Endothelia Display Differential Functional Fractalkine (CX3CL1) Expression by Angiotensin-II.
Rius C, Piqueras L, González-Navarro H, Albertos F, Company C, López-Ginés C, Ludwig A, Blanes JI, Morcillo EJ, Sanz MJ
Arteriosclerosis, thrombosis, and vascular biology. 2013 Jan. 96-104. FI: 6.338
Assessing clinical and functional outcomes in a gene-environment interaction study in first episode of psychosis (PEPs).
Bernardo M, Bioque M, Parellada M, Saiz Ruiz J, Cuesta MJ, Llerena A, Sanjuán J, Castro-Fornieles J, Arango C, Cabrera B, PEPs Group
Revista de psiquiatrí?a y salud mental. 2013 Jan. 42461. FI: 0.667
Beliefs about illness and their relationship with hopelessness, depression, insight and suicide attempts in schizophrenia.
Acosta FJ, Aguilar EJ, Cejas MR, Gracia R
Psychiatria Danubina. 2013 Mar. 49-54. FI: 0.633
Bisphosphonates-related osteonecrosis of the jaws: a preliminary study of salivary interleukins.
Bagan J, Sheth CC, Soria JM, Margaix M, Bagan L
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2013 May. 405-8. FI: 2.055
Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.
Pagano G, Talamanca AA, Castello G, d'Ischia M, Pallardó FV, Petrovi? S, Porto B, Tiano L, Zatterale A
European journal of haematology. 2013 Aug. 141-51. FI: 2.548
Deferiprone and idebenone rescue frataxin depletion phenotypes in a Drosophila model of Friedreich's ataxia.
Soriano S, Llorens JV, Blanco-Sobero L, Gutiérrez L, Calap-Quintana P, Morales MP, Moltó MD, Martínez-Sebastián MJ
Gene. 2013 Jun 1. 274-81. FI: 2.196
Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: the PREDIMED study.
Tresserra-Rimbau A, Medina-Remón A, Pérez-Jiménez J, Martínez-González MA, Covas MI, Corella D, Salas-Salvadó J, Gómez-Gracia E, Lapetra J, Arós F, Fiol M, Ros E, Serra-Majem L, Pintó X, Muñoz MA, Saez GT, Ruiz-Gutiérrez V, Warnberg J, Estruch R, Lamuela-Raventós RM
Nutrition, metabolism, and cardiovascular diseases : NMCD. 2013 Oct. 953-9. FI: 3.978
Functional neuroimaging in the study of aggressive behaviour in patients with schizophrenia.
Garciá-Martí G, Martí-Bonmatí L, Aguilar EJ, Sanz-Requena R, Alberich-Bayarri Á, Bonmatí A, Sanjuán J
Revista de neurologia. 2013 Feb 16. 193-9. FI: 1.179
Improvement in sprint performance: doping or nature?
Lippi G, Sanchis-Gomar F
Drug testing and analysis. 2013 Feb. 135. FI: 3.276
Integrating information about imaging biomarkers into structured radiology reports.
Pomar-Nadal A, Pérez-Castillo C, Alberich-Bayarri A, García-Martí G, Sanz Requena R, Martí-Bonmatí L
Radiología. 2013 May - June. 188-194
Olfactory reference syndrome: a systematic review.
Arenas B, Garcia G, Gómez J, Renovell M, García V, Olucha-Bordonau FE, Sanjuán J
Revista de neurologia. 2013 Jan 16. 65-71. FI: 1.179
Primary prevention of cardiovascular disease with a Mediterranean diet.
Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, Gómez-Gracia E, Ruiz-Gutiérrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA, PREDIMED Study Investigators
The New England journal of medicine. 2013 Apr 4. 1279-90. FI: 51.658
Revista Española de Cardiología: Keeping Its Finger on the Pulse of the Digital Age.
Avanzas P, Bayes-Genis A, Pérez de Isla L, Sanchis J, Heras M
Revista española de cardiología. 2013 Dec. 996-998. FI: 3.204
Structural plasticity of interneurons in the adult brain: role of PSA-NCAM and implications for psychiatric disorders.
Nacher J, Guirado R, Castillo-Gómez E
Neurochemical research. 2013 Jun. 1122-33. FI: 2.125
Study of oxidative stress in patients with advanced renal disease and undergoing either hemodialysis or peritoneal dialysis.
Puchades MJ, Saez G, Muñoz MC, Gonzalez M, Torregrosa I, Juan I, Miguel A
Clinical nephrology. 2013 Sep. 177-86. FI: 1.288
The circuits of the olfactory bulb. The exception as a rule.
Crespo C, Liberia T, Blasco-Ibáñez JM, Nácher J, Varea E
Anatomical record (Hoboken, N.J. : 2007). 2013 Sep. 1401-12. FI: 1.343
[Eating disorders: Considerations on nosology, etiology and treatment in the XXI century].
Rojo Moreno L, Plumed Domingo J, Conesa Burguet L, Vaz Leal F, Diaz Marsá M, Rojo-Bofill L, Livianos Aldana L
Revista de psiquiatrí?a y salud mental. 2012 Jul. 197-204. FI: 0.667
[Effects of methylphenidate on anxiety].
Sanchez-Perez AM, Garcia-Aviles A, Gasco HA, Sanjuan J, Olucha-Bordonau FE
Revista de neurologia. 2012 Oct 16. 499-506. FI: 1.179
[Recommendations for the prevention and management of suicidal behaviour].
Ayuso-Mateos JL, Baca-García E, Bobes J, Giner J, Giner L, Pérez V, Sáiz PA, Saiz Ruiz J, Grupo RECOMS
Revista de psiquiatrí?a y salud mental. 2012 Jan-Mar. 45139. FI: 0.667
[Relationship between insight, violence and diagnoses in psychotic patients].
Lera Calatayud G, Herrero Sebastián N, Aguilar García-Iturrospe E, González Piqueras JC, Sanjuán Arias J, Leal Cercós C
Revista de psiquiatrí?a y salud mental. 2012 Jan. 43-7. FI: 0.667
[Validation of the Spanish version of the Subjective Well-being under Neuroleptic Scale (SWN-K) in patients with schizophrenia].
Sanjúan J, Haro JM, Mauriño J, Díez T, Ballesteros J
Medicina clínica. 2012 Feb 25. 151-4. FI: 1.399
Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patients.
Gilabert-Juan J, Varea E, Guirado R, Blasco-Ibáñez JM, Crespo C, Nácher J
Neuroscience letters. 2012 Nov 14. 97-102. FI: 2.026
Altered expression of neuropeptides in the primary somatosensory cortex of the Down syndrome model Ts65Dn.
Hernández S, Gilabert-Juan J, Blasco-Ibáñez JM, Crespo C, Nácher J, Varea E
Neuropeptides. 2012 Feb. 29-37. FI: 2.067
Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia.
Carrera N, Arrojo M, Sanjuán J, Ramos-Ríos R, Paz E, Suárez-Rama JJ, Páramo M, Agra S, Brenlla J, Martínez S, Rivero O, Collier DA, Palotie A, Cichon S, Nöthen MM, Rietschel M, Rujescu D, Stefansson H, Steinberg S, Sigurdsson E, Clair DS, Tosato S, Werge T, Stefansson K, González JC, Valero J, Gutiérrez-Zotes A, Labad A, Martorell L, Vilella E, Carracedo A, Costas J
Biological psychiatry. 2012 Jan 15. 169-77. FI: 9.247
Brain atrophy and lesion load are related to CSF lipid-specific IgM oligoclonal bands in clinically isolated syndromes.
Magraner MJ, Bosca I, Simó-Castelló M, García-Martí G, Alberich-Bayarri A, Coret F, Alvarez-Cermeño JC, Martí-Bonmatí L, Villar LM, Casanova B
Neuroradiology. 2012 Jan. 41978. FI: 2.7
Characterization of a population of tyrosine hydroxylase-containing interneurons in the external plexiform layer of the rat olfactory bulb.
Liberia T, Blasco-Ibáñez JM, Nácher J, Varea E, Zwafink V, Crespo C
Neuroscience. 2012 Aug 16. 140-53. FI: 3.122
Chronic fluoxetine treatment in middle-aged rats induces changes in the expression of plasticity-related molecules and in neurogenesis.
Guirado R, Sanchez-Matarredona D, Varea E, Crespo C, Blasco-Ibanez JM, Nacher J
BMC neuroscience. 2012 Jan 5. 5. FI: 3
Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy.
Betancor G, Garriga C, Puertas MC, Nevot M, Anta L, Blanco JL, Pérez-Elías MJ, de Mendoza C, Martínez MA, Martinez-Picado J, Menéndez-Arias L, Resistance Platform of the Spanish AIDS Research Network (ResRIS), Iribarren JA, Caballero E, Ribera E, Llibre JM, Clotet B, Jaén A, Dalmau D, Gatel JM, Peraire J, Vidal F, Vidal C, Riera M, Córdoba J, López Aldeguer J, Galindo MJ, Gutiérrez F, Álvarez M, García F, Pérez-Romero P, Viciana P, Leal M, Palomares JC, Pineda JA, Viciana I, Santos J, Rodríguez P, Gómez Sirvent JL, Gutiérrez C, Moreno S, Pérez-Olmeda M, Alcamí J, Rodríguez C, del Romero J, Cañizares A, Pedreira J, Miralles C, Ocampo A, Morano L, Aguilera A, Garrido C, Manuzza G, Poveda E, Soriano V
Retrovirology. 2012 Aug 13. 68. FI: 5.657
Cognitive impairment is related to oxidative stress and chemokine levels in first psychotic episodes.
Martínez-Cengotitabengoa M, Mac-Dowell KS, Leza JC, Micó JA, Fernandez M, Echevarría E, Sanjuan J, Elorza J, González-Pinto A
Schizophrenia research. 2012 May. 66-72. FI: 4.59
Distribution and targets of the relaxin-3 innervation of the septal area in the rat.
Olucha-Bordonau FE, Otero-García M, Sánchez-Pérez AM, Núñez A, Ma S, Gundlach AL
The Journal of comparative neurology. 2012 Jun 15. 1903-39. FI: 3.661
Examining the course of hallucinatory experiences in children and adolescents: a systematic review.
Rubio JM, Sanjuán J, Flórez-Salamanca L, Cuesta MJ
Schizophrenia research. 2012 Jul. 248-54. FI: 4.59
Expression of PSA-NCAM and synaptic proteins in the amygdala of psychiatric disorder patients.
Varea E, Guirado R, Gilabert-Juan J, Martí U, Castillo-Gomez E, Blasco-Ibáñez JM, Crespo C, Nacher J
Journal of psychiatric research. 2012 Feb. 189-97. FI: 4.066
Genetic and functional characterization of a yet-unclassified rhizobial Dtr (DNA-transfer-and-replication) region from a ubiquitous plasmid conjugal system present in Sinorhizobium meliloti, in Sinorhizobium medicae, and in other nonrhizobial Gram-negativ
Giusti Mde L, Pistorio M, Lozano MJ, Tejerizo GA, Salas ME, Martini MC, López JL, Draghi WO, Del Papa MF, Pérez-Mendoza D, Sanjuán J, Lagares A
Plasmid. 2012 May. 199-210. FI: 1.276
Involuntary outpatient treatment (iot) for severe mental patients: current situation in Spain.
Cañete-Nicolás C, Hernández-Viadel M, Bellido-Rodríguez C, Lera-Calatayud G, Asensio-Pascual P, Pérez-Prieto JF, Calabuig-Crespo R, Leal-Cercós C
Actas españolas de psiquiatría. 2012 Jan-Feb. 27-33. FI: 0.452
Multimodal morphometry and functional magnetic resonance imaging in schizophrenia and auditory hallucinations.
García-Martí G, Aguilar EJ, Martí-Bonmatí L, Escartí MJ, Sanjuán J
World journal of radiology. 2012 Apr 28. 159-66
New scenarios for neuronal structural plasticity in non-neurogenic brain parenchyma: the case of cortical layer II immature neurons.
Bonfanti L, Nacher J
Progress in neurobiology. 2012 Jul. 42005. FI: 9.035
Post-weaning social isolation rearing influences the expression of molecules related to inhibitory neurotransmission and structural plasticity in the amygdala of adult rats.
Gilabert-Juan J, Moltó MD, Nacher J
Brain research. 2012 Apr 11. 129-36. FI: 2.879
Research letter: is neuroticism a risk factor for postpartum depression?
Martín-Santos R, Gelabert E, Subirà S, Gutierrez-Zotes A, Langorh K, Jover M, Torrens M, Guillamat R, Mayoral F, Canellas F, Iborra JL, Gratacos M, Costas J, Gornemann I, Navinés R, Guitart M, Roca M, DE Frutos R, Vilella E, Valdés M, Esteve LG, Sanjuan J
Psychological medicine. 2012 Jul. 1559-65. FI: 5.587
The crisis of psychiatry - insights and prospects from evolutionary theory.
Brüne M, Belsky J, Fabrega H, Feierman HR, Gilbert P, Glantz K, Polimeni J, Price JS, Sanjuan J, Sullivan R, Troisi A, Wilson DR
World psychiatry : official journal of the World Psychiatric Association (WPA). 2012 Feb. 55-7. FI: 8.974
The role of striatal dopamine D2 receptors in the occurrence of extrapyramidal side effects: iodine-123-iodobenzamide single photon emission computed tomography study.
Corripio I, Ferreira A, Portella MJ, Pérez V, Escartí MJ, Del Valle Camacho M, Sauras RB, Alonso A, Grasa EM, Carrió I, Catafau AM, Alvarez E
Psychiatry research. 2012 Jan 30. 73-7. FI: 2.456

Investigación de marcadores biológicos y nuevas estrategias terapéuticas en la Psicosis

Referencia:
Prometeo 2016/082
Investigador principal:
Julio Sanjuán Arias
Entidad financiadora:
Generalitat Valenciana
Duración:
01/01/2016 - 31/12/2019
Presupuesto total:
€179.940

Plasticity of perisomatic inhibition on pyramidal neurons of the  prefrontal cortex: impact of peripubertal stress and implcation in psychiatric disorders Kind of contract

Referencia:
SAF2015-68436-R
Investigador principal:
Juan Salvador Nàcher Roselló
Entidad financiadora:
Ministerio de Economía y Competitividad
Duración:
01/01/2016 - 31/12/2019
Presupuesto total:
€160.000

Identification of genetic factors involved on FXN transcriptional silencing mediated by the GAA repeat expansion. LOI Bronya J Keats International Research Collaboration Award

Referencia:
Investigador principal:
Mª Dolores Moltó Ruiz
Entidad financiadora:
Friedreich’s Ataxia Research Alliance (FARA)
Duración:
01/02/2016 - 31/05/2017
Presupuesto total:
€0

Eficacia del entrenamiento metacognitivo individualizado (EMC+) en personas con psicosis de reciente evolución.

Referencia:
PI14/00044
Investigador principal:
Susana Ochoa
Entidad financiadora:
Instituto de Salud Carlos III
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€0

Aplicación para dispositivos móviles vinculada a la historia clínica electrónica para mejorar la adherencia al tratamiento en pacientes con psicosis.

Referencia:
INCLIVA 6
Investigador principal:
Julio Sanjuán
Entidad financiadora:
INCLIVA
Duración:
01/01/2015 - 31/12/2015
Presupuesto total:
€4.000

Identificación de biomarcadores en enfermedades neurodegenerativas mediante el uso de modelos biomédicos

Referencia:
Programa VLC‐BIOMED‐I
Investigador principal:
Mª Dolores Moltó Ruiz
Entidad financiadora:
Duración:
01/01/2015 - 31/12/2015
Presupuesto total:
€0

European brain imaging network for psychosis (EBINP)

Referencia:
SIN EXPEDIENTE INTRAMURAL INCLIVA XIX
Investigador principal:
Julio Sanjuán Arias
Entidad financiadora:
Fundación Investigación Hospital Clínico Universitario de Valencia
Duración:
01/01/2014 - 31/12/2014
Presupuesto total:
€4.000

PATENTE

Título: A method for detection of abnormal brain areas using magnetic resonance imaging

Inventores: G. García, J. Sanjuán, L. Martí-Bonmatí, R. Sanz, Á. Alberich y J. V. Manjón
Titular: CIBERSAM
Número de solicitud: P201331901
Fecha de prioridad: 23/12/2013
Territorio: España

Investigadores valencianos demuestran la capacidad de cambio de la estructura y conectividad de las interneuronas en el cerebro adulto

Investigadores de INCLIVA y de la Universidad de Valencia muestran la capacidad de cambio de la estructura y conectividad de las interneuronas en el cerebro adulto, el puente de comunicación entre las neuronas.

Publicado el 02/09/2017.Leer más »

El Dr. Aguilar, psiquiatra, premiado por la RAMCV

El Dr. Eduardo J. Aguilar recibe el premio al mejor trabajo de investigación 2015 y el título de académico correspondiente.
El estudio profundiza en los mecanismos cerebrales involucrados en el efecto de la psicoterapia en pacientes psicóticos con alucinaciones auditivas persistentes.

Publicado el 28/06/2016.Leer más »

Investigadores de INCLIVA y la UV concluyen que una proteína podría influir en la maduración de neuronas del cerebro adulto

El estudio se ha desarrollado en colaboración con el Instituto de Neurociencias de Helsinki. La proteína es la reelina, básica en el desarrollo y la plasticidad neuronal. Esta molécula se encuentra alterada en ratones que sufren una mutación espontánea en su gen, conocidos como “ratones reeler".

Publicado el 04/05/2016.Leer más »