Área Metabolismo

Grupo de Investigación en Problemas Respiratorios de las Enfermedades Neuromusculares

Emilio Servera Pieras

El Dr. Servera cursa sus estudios de Medicina en la Facultad de la Universidad de Valencia, donde se licencia en 1976  y obtiene su doctorado con premio extraordinario.

Realiza su residencia en el Hospital Clínico Universitario de Valencia y, gracias a una Beca del Gobierno Francés, completa su formación predoctoral con una estancia en la Unidad de Investigación INSERM de Fisiopatología Respiratoria de Nancy (Francia) y en el Servicio de Insuficiencia Respiratoria del Hospital Universitario, dirigidos ambos por el Profesor P. Sadoul. En 1983 obtuvo el Diploma Universitario de Fisiopatología Respiratoria, por la Universidad de Nancy. Con posterioridad ha realizado estancias en Lyon (Francia) y New Jersey, en relación con la ventilación mecánica en domicilio.  Actualmente es Jefe del Servicio de Neumología el Hospital Clínico Universitario de Valencia.

Su labor docente está asociada desde su fundación a la hoy Facultad de Fisioterapia de la Universidad de Valencia, donde enseña Patología Respiratoria. Está acreditado como Catedrático de Universidad. 

Sus investigaciones se han centrado en el campo de la Insuficiencia Respiratoria, fundamentalmente en rehabilitación respiratoria y en la ventilación mecánica no invasiva y mediante traqueotomía. Sus publicaciones sobre los problemas respiratorios de los enfermos neuromusculares se citan de forma regular en las guías de práctica clínica internacionales y forma parte de comisiones nacionales e internacionales de expertos en esta área.  La Unidad de Cuidados Respiratorios del Servicio que dirige ha sido pionera en España y está calificada como Unidad de Excelencia. 

 

Grupo de investigación en problemas respiratorios de las enfermedades neuromusculares

Investigador colaborador

Jesús Sancho Chinesta
María Pilar Barreto Martín
José Blanquer Olivas
Julio Marín Pardo
José Luís Díaz Cordobés
Pilar Bañuls Polo
Manuela Marín González
Mª Luisa Briones Urtiaga
Mª Jesús Zafra Pirés
María Belén Safont Muñoz
Mª Cruz González Villaescusa
José Vicente Ferreres Franco
Enric Burés Sales
Nuria Garrido Zafra
Jaime Signes-Costa Miñana
  • Valorar la utilidad de las técnicas de tos asistida mecánicamente con in-exuflación y oscilaciones de alta frecuencia en los pacientes con esclerosis lateral amiotrófica tanto en situaciones de estabilidad médica como durante las exacerbaciones respiratorias.
  • Identificar aquellos indicadores que permitan predecir la incapacidad de mantener la ventilación espontanea en pacientes en ELA tanto en situaciones de estabilidad clínica como durante exacerbaciones agudas.
  • Establecer el rol de la afectación bulbar y el papel de las asincronías del fallo de la ventilación no invasiva durante las exacerbaciones agudas de los pacientes con ELA.
  • Mostrar la efectividad de un programa de intervención psicológica sobre el distres emocional en pacientes con ELA y sus cuidadores.
  • Contribuir a mostrar la relevancia en la identificación de los agentes etiológicos en los estudios genéticos epidemiológicos de la sepsis. 
Número total de publicaciones: 81. Factor de Impacto acumulado: 232.14
The potential role of 13-valent pneumococcal conjugate vaccine in preventing respiratory complications in bacteraemic pneumococcal community-acquired pneumonia.
Sanz-Herrero F, Gimeno-Cardona C, Tormo-Palop N, Fernández-Fabrellas E, Briones ML, Cervera-Juan Á, Blanquer-Olivas J
Vaccine.. 2016 Apr 4. 1847-52. FI: 3.624
The Contribution of Cell Blocks in the Diagnosis of Mediastinal Masses and Hilar Adenopathy Samples from Echobronchoscopy.
Franco Serrano J, Burés Sales E
Archivos de bronconeumología.. 2016 Feb. 107. FI: 1.823
Pulmonary Strongyloides stercoralis infection.
Esteban Ronda V, Franco Serrano J, Briones Urtiaga ML
Archivos de bronconeumología.. 2016 Mar 22. . FI: 1.771
Serum caspase 3 levels are associated with early mortality in severe septic patients.
Lorente L, Martín MM, Ferreres J, Solé-Violán J, Labarta L, Díaz C, Jiménez A, Borreguero-León JM
Journal of critical care.. 2016 Aug. 103-6. FI: 2.445
Demoralization Scale in Spanish-Speaking Palliative Care Patients.
Rudilla D, Galiana L, Oliver A, Barreto P
Journal of pain and symptom management.. 2016 Apr. 769-775.e1. FI: 2.795
Effect of High-Frequency Oscillations on Cough Peak Flows Generated by Mechanical In-Exsufflation in Medically Stable Subjects With Amyotrophic Lateral Sclerosis.
Sancho J, Bures E, de La Asunción S, Servera E
Respiratory care.. 2016 May 17. . FI: 1.838
A new measure of home care patients' dignity at the end of life: The Palliative Patients' Dignity Scale (PPDS).
Rudilla D, Oliver A, Galiana L, Barreto P
Palliative & supportive care.. 2016 Apr. 99-108. FI: 1.525
Accuracy of PaO2 /FiO2 calculated from SpO2 for severity assessment in ED patients with pneumonia.
Sanz F, Dean N, Dickerson J, Jones B, Knox D, Fernández-Fabrellas E, Chiner E, Briones ML, Cervera Á, Aguar MC, Blanquer J
Respirology (Carlton, Vic.). 2015 Jul. 813-8. FI: 3.345
Association between serum substance P levels and mortality in patients with severe sepsis.
Lorente L, Martín MM, Almeida T, Hernández M, Ferreres J, Solé-Violán J, Labarta L, Díaz C, Jiménez A
Journal of critical care.. 2015 Oct. 924-8. FI: 1.995
Association between serum total antioxidant capacity and mortality in severe septic patients.
Lorente L, Martín MM, Almeida T, Abreu-González P, Ferreres J, Solé-Violán J, Labarta L, Díaz C, Jiménez A
Journal of critical care. 2015 Feb. 217.e7-12. FI: 1.995
Bulbar impairment score predicts noninvasive volume-cycled ventilation failure during an acute lower respiratory tract infection in ALS.
Servera E, Sancho J, Bañuls P, Marín J
Journal of the neurological sciences.. 2015 Nov 15. 87-91. FI: 2.474
Candida tropicalis bloodstream infection: Incidence, risk factors and outcome in a population-based surveillance.
Fernández-Ruiz M, Puig-Asensio M, Guinea J, Almirante B, Padilla B, Almela M, Díaz-Martín A, Rodríguez-Baño J, Cuenca-Estrella M, Aguado JM, CANDIPOP Project, GEIH-GEMICOMED (SEIMC), REIPI
The Journal of infection.. 2015 Sep. 385-94. FI: 4.441
Chromogranin A levels and mortality in patients with severe sepsis.
Hsu CH, Reyes LF, Orihuela CJ, Buitrago R, Anzueto A, Soni NJ, Levine S, Peters J, Hinojosa CA, Aliberti S, Sibila O, Rodriguez A, Chalmers JD, Martin-Loeches I, Bordon J, Blanquer J, Sanz F, Marcos PJ, Rello J, Solé-Violán J, Restrepo MI
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.. 2015. 171-6. FI: 2.26
Comparing counseling and dignity therapies in home care patients: A pilot study.
Rudilla D, Galiana L, Oliver A, Barreto P
Palliative & supportive care.. 2015 Oct 14. 42614. FI: 1.525
Decrease of oxidative phosphorylation system function in severe septic patients.
Lorente L, Martín MM, López-Gallardo E, Blanquer J, Solé-Violán J, Labarta L, Díaz C, Jiménez A, Montoya J, Ruiz-Pesini E
Journal of critical care.. 2015 Oct. 935-9. FI: 1.995
Degree of adherence to recommended antiviral treatment during the pandemic and post-pandemic periods of influenza A(H1N1)pdm09 in 148 intensive care units in Spain.
Canadell L, Martín-Loeches I, Díaz E, Trefler S, Grau S, Yebenes JC, Almirall J, Olona M, Sureda F, Blanquer J, Rodriguez A, GETGAG
Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2015 May. 222-33. FI: 1.336
Effectiveness of non-pharmaceutical measures in preventing pediatric influenza: a case-control study.
Torner N, Soldevila N, Garcia JJ, Launes C, Godoy P, Castilla J, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
BMC public health. 2015 Jun 9. 543. FI: 2.264
Predictors of need for noninvasive ventilation during respiratory tract infections in medically stable, non-ventilated subjects with amyotrophic lateral sclerosis.
Sancho J, Servera E, Bañuls P, Marin J
Respiratory care. 2015 Apr. 492-7. FI: 1.838
Prognosis Biomarkers of Severe Sepsis and Septic Shock by 1H NMR Urine Metabolomics in the Intensive Care Unit.
Garcia-Simon M, Morales JM, Modesto-Alapont V, Gonzalez-Marrachelli V, Vento-Rehues R, Jorda-Miñana A, Blanquer-Olivas J, Monleon D
PLoS hub for clinical trials. 2015. e0140993. FI: 3.234
Serum melatonin levels are associated with mortality in severe septic patients.
Lorente L, Martín MM, Abreu-González P, de la Cruz T, Ferreres J, Solé-Violán J, Labarta L, Díaz C, Jiménez A, Borreguero-León JM
Journal of critical care. 2015 Aug. 860.e1-6. FI: 1.995
Spirituality in patients with advanced illness: The role of symptom control, resilience and social network.
Fombuena M, Galiana L, Barreto P, Oliver A, Pascual A, Soto-Rubio A
Journal of health psychology.. 2015 May 28. . FI: 1.748
The 4G/4G Genotype of PAI-1 Polymorphism Is Associated with Higher Plasma PAI-1 Concentrations and Mortality in Patients with Severe Sepsis.
Lorente L, Martín MM, Borreguero-León JM, Barrios Y, Solé-Violán J, Ferreres J, Labarta L, Díaz C, Jiménez A
PloS one. 2015. e0129565. FI: 3.234
Tolerance of Volume Control Noninvasive Ventilation in Subjects With Amyotrophic Lateral Sclerosis.
Martínez D, Sancho J, Servera E, Marín J
Respiratory care.. 2015 Dec. 1765-71. FI: 1.838
Predictive factors of severe multilobar pneumonia and shock in patients with influenza.
Garcia Gutierrez S, Quintana JM, Baricot M, Bilbao A, Capelastegui A, Cilla Eguiluz CG, Domínguez A, Castilla J, Godoy P, Delgado-Rodríguez M, Soldevila N, Astray J, Mayoral JM, Martín V, González-Candelas F, Galán JC, Tamames S, Castro-Acosta AA, Garín O, Pumarola T, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Emergency medicine journal : EMJ. 2014 Apr. 301-7. FI: 1.776
Non-invasive ventilation effectiveness and the effect of ventilatory mode on survival in ALS patients.
Sancho J, Servera E, Morelot-Panzini C, Salachas F, Similowski T, Gonzalez-Bermejo J
Amyotrophic lateral sclerosis and frontotemporal degeneration. 2014 Mar. 55-61. FI: 2.591
Association between Serum Tissue Inhibitor of Matrix Metalloproteinase-1 Levels and Mortality in Patients with Severe Brain Trauma Injury.
Lorente L, Martín MM, López P, Ramos L, Blanquer J, Cáceres JJ, Solé-Violán J, Solera J, Cabrera J, Argueso M, Ortiz R, Mora ML, Lubillo S, Jiménez A, Borreguero-León JM, González A, Orbe J, Rodríguez JA, Páramo JA
PloS one. 2014. e94370. FI: 3.534
Association of Sepsis-Related Mortality with Early Increase of TIMP-1/MMP-9 Ratio.
Lorente L, Martín MM, Solé-Violán J, Blanquer J, Labarta L, Díaz C, Borreguero-León JM, Orbe J, Rodríguez JA, Jiménez A, Páramo JA
PloS one. 2014. e94318. FI: 3.534
Community-acquired Pneumonia Among Smokers.
Almirall J, Blanquer J, Bello S
Archivos de bronconeumología. 2014 Jun. 250-254. FI: 1.816
Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain.
Puig-Asensio M, Padilla B, Garnacho-Montero J, Zaragoza O, Aguado JM, Zaragoza R, Montejo M, Muñoz P, Ruiz-Camps I, Cuenca-Estrella M, Almirante B, CANDIPOP Project, GEIH-GEMICOMED (SEIMC), REIPI
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2014 Apr. O245-54. FI: 5.197
ALS: Control ventilation, manage respiratory secretions and, when required, oversee the process of dying.
Servera E, Sancho J
Revista portuguesa de pneumologia. 2014 Jul-Aug. 177-8. FI: 0.855
Higher platelet cytochrome oxidase specific activity in surviving than in non-surviving septic patients.
Lorente L, Martín MM, López-Gallardo E, Iceta R, Blanquer J, Solé-Violán J, Labarta L, Díaz C, Jiménez A, Montoya J, Ruiz-Pesini E
Critical care (London, England). 2014 Jun 30. R136
Surfactant protein A genetic variants associate with severe respiratory insufficiency in pandemic influenza A virus infection.
Herrera-Ramos E, López-Rodríguez M, Ruíz-Hernández JJ, Horcajada JP, Borderías L, Lerma E, Blanquer J, Pérez-González MC, García-Laorden MI, Florido Y, Mas-Bosch V, Montero M, Ferrer JM, Sorlí L, Vilaplana C, Rajas O, Briones M, Aspa J, López-Granados E, Solé-Violán J, Rodríguez de Castro F, Rodríguez-Gallego C
Critical care (London, England). 2014 Jun 20. R127
Sustained high plasma plasminogen activator inhibitor-1 levels are associated with severity and mortality in septic patients.
Lorente L, Martín MM, Borreguero-León JM, Solé-Violán J, Ferreres J, Labarta L, Díaz C, Jiménez A, Páramo JA
Thrombosis research. 2014 Jul. 182-6. FI: 2.427
Red Blood Cell Distribution Width during the First Week Is Associated with Severity and Mortality in Septic Patients.
Lorente L, Martín MM, Abreu-González P, Solé-Violán J, Ferreres J, Labarta L, Díaz C, González O, García D, Jiménez A, Borreguero-León JM
PloS one. 2014. e105436. FI: 3.534
Impact of therapeutic strategies on the prognosis of candidemia in the ICU.
Puig-Asensio M, Pemán J, Zaragoza R, Garnacho-Montero J, Martín-Mazuelos E, Cuenca-Estrella M, Almirante B, Prospective Population Study on Candidemia in Spain (CANDIPOP) Project, Hospital Infection Study Group (GEIH), Medical Mycology Study Group (GEMICOMED) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), Spanish Network for Research in Infectious Diseases
Critical care medicine. 2014 Jun. 1423-32. FI: 6.147
Pulmonary rehabilitation.
Güell Rous MR, Díaz Lobato S, Rodríguez Trigo G, Morante Vélez F, San Miguel M, Cejudo P, Ortega Ruiz F, Muñoz A, Galdiz Iturri JB, García A, Servera E
Archivos de bronconeumología. 2014 Aug. 332-44. FI: 1.816
Does prolonged onset of symptoms have a prognostic significance in community-acquired pneumonia?
Sanz F, Restrepo MI, Fernández-Fabrellas E, Cervera A, Briones ML, Novella L, Aguar MC, Chiner E, Fernandez JF, Blanquer J
Respirology (Carlton, Vic.). 2014 Oct. 1073-9. FI: 3.495
Initial use of echinocandins does not negatively influence outcome in Candida parapsilosis bloodstream infection: a propensity score analysis.
Fernández-Ruiz M, Aguado JM, Almirante B, Lora-Pablos D, Padilla B, Puig-Asensio M, Montejo M, García-Rodríguez J, Pemán J, Ruiz Pérez de Pipaón M, Cuenca-Estrella M, CANDIPOP Project, GEIH-GEMICOMED (SEIMC), REIPI
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014 May. 1413-21. FI: 9.416
Effect of a short-term psychological intervention on the anxiety and depression of amyotrophic lateral sclerosis patients.
Díaz JL, Sancho J, Barreto P, Bañuls P, Renovell M, Servera E
Journal of health psychology. 2014 Nov 4. . FI: 1.826
Pandemic influenza A (H1N1) in non-vaccinated, pregnant women in Spain (2009-2010).
Morales-Suárez-Varela M, González-Candelas F, Astray J, Alonso J, Castro A, Cantón R, Galán JC, Garin O, Soldevila N, Baricot M, Castilla J, Godoy P, Delgado-Rodríguez M, Martín V, Mayoral JM, Pumarola T, Quintana JM, Tamames S, Llopis-González A, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Maternal and child health journal. 2014 Aug. 1454-61. FI: 2.015
Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011.
Guinea J, Zaragoza Ó, Escribano P, Martín-Mazuelos E, Pemán J, Sánchez-Reus F, Cuenca-Estrella M, CANDIPOP Project, GEIH-GEMICOMED (SEIMC), and REIPI
Antimicrobial agents and chemotherapy. 2014. 1529-37. FI: 4.451
Incidence and diagnosis of ventilator-associated tracheobronchitis in the intensive care unit: an international online survey.
Rodríguez A, Póvoa P, Nseir S, Salluh J, Curcio D, Martín-Loeches I, TAVeM group investigators
Critical care (London, England). 2014 Feb 12. R32
Pandemic influenza A (H1N1) infection in pregnant and nonpregnant women in Spain (2009-2010).
Suárez-Varela MM, González-Candelas F, Astray J, Alonso J, Garin O, Castro A, Galán JC, Baricot M, Castilla J, Godoy P, Delgado-Rodríguez M, Martin V, Mayoral JM, Pumarola T, Quintana JM, Tamames S, Llopis-González A, Dominguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Japanese journal of infectious diseases. 2014. 163-71. FI: 1.204
EPICO 2.0 project. Development of educational therapeutic recommendations using the DELPHI technique on invasive candidiasis in critically ill adult patients in special situations.
Zaragoza R, Ferrer R, Maseda E, Llinares P, Rodriguez A, EPICO Project Group
Revista iberoamericana de micologia. 2014 Jul-Sep. 157-75. FI: 0.971
Inter-regional changes in the performance and interpretation of spirometry in Spain: 3E study.
López-Campos JL, Soriano JB, Calle M, 3E Project
Archivos de bronconeumologia. 2014 Nov. 475-83. FI: 1.816
Report of 38 cases of tracheobronchitis in non-immunocompromised patients with dual isolation of Aspergillus in lower respiratory tract samples.
Barberán J, Sánchez-Haya E, del Castillo D, Sanz F, Alcázar B, Malmierca E, ASP Investigator Group
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia. 2014 Jun. 110-4. FI: 0.905
Serum levels of caspase-cleaved cytokeratin-18 and mortality are associated in severe septic patients: pilot study.
Lorente L, Martín MM, González-Rivero AF, Ferreres J, Solé-Violán J, Labarta L, Díaz C, Jiménez A, Borreguero-León JM
PloS one. 2014. e109618. FI: 3.534
Pulmonologists, mechanical ventilation and complementary techniques.
Servera E, Sancho J
Archivos de bronconeumologia. 2014 Dec. 505-6. FI: 1.816
Assessing an Improved Protocol for Plasma microRNA Extraction.
Moret I, Sánchez-Izquierdo D, Iborra M, Tortosa L, Navarro-Puche A, Nos P, Cervera J, Beltrán B
PloS one. 2013 Dec 23. e82753. FI: 3.73
Buccal bone crest dynamics after immediate implant placement and ridge preservation techniques: review of morphometric studies in animals.
Viña-Almunia J, Candel-Martí ME, Cervera-Ballester J, García-Mira B, Calvo-Guirado JL, Peñarrocha-Oltra D, Peñarrocha-Diago M
Implant dentistry. 2013 Apr. 155-60. FI: 1.404
Community-acquired Legionella Pneumonia in the intensive care unit: Impact on survival of combined antibiotic therapy.
Rello J, Gattarello S, Souto J, Sole-Violan J, Valles J, Peredo R, Zaragoza R, Vidaur L, Parra A, Roig J, Community-Acquired Pneumonia in Unidad de Cuidados Intensivos 2 CAPUCI 2 Study Investigators
Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias. 2013 Jun-Jul. 320-6. FI: 1.323
Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain.
Delgado-Rodríguez M, Castilla J, Godoy P, Martín V, Soldevila N, Alonso J, Astray J, Baricot M, Galán JC, Castro A, Gónzález-Candelas F, Mayoral JM, Quintana JM, Pumarola T, Tamames S, Sáez M, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Influenza and other respiratory viruses. 2013 Nov. 1336-42. FI: 1.471
Early non-invasive ventilation treatment for severe influenza pneumonia.
Masclans JR, Pérez M, Almirall J, Lorente L, Marqués A, Socias L, Vidaur L, Rello J, H1N1 GTEI/SEMICYUC Investigators
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2013 Mar. 249-56. FI: 4.578
Effectiveness of vaccination with 23-valent pneumococcal polysaccharide vaccine in preventing hospitalization with laboratory confirmed influenza during the 2009-2010 and 2010-2011 seasons.
Domínguez A, Castilla J, Godoy P, Delgado-Rodríguez M, Saez M, Soldevila N, Astray J, Mayoral JM, Martín V, Quintana JM, González-Candelas F, Galán JC, Tamames S, Castro A, Baricot M, Garín O, Pumarola T, CIBERESP Cases and Controls in Pandemic Influenza Working Group (Spain)
Human vaccines & immunotherapeutics. 2013 Apr. 865-73
Electrolytic lesion of the nucleus incertus retards extinction of auditory conditioned fear.
Pereira CW, Santos FN, Sánchez-Pérez AM, Otero-García M, Marchioro M, Ma S, Gundlach AL, Olucha-Bordonau FE
Behavioural brain research. 2013 Jun 15. 201-10. FI: 3.327
Epidemiology, clinical features, and prognosis of elderly adults with severe forms of influenza A (H1N1.
Garnacho-Montero J, Gutiérrez-Pizarraya A, Màrquez JA, Zaragoza R, Granada R, Ruiz-Santana S, Rello J, Rodríguez A, Spanish Society of Intensive Care Medicine and Coronary Units Working Group
Journal of the American Geriatrics Society. 2013 Mar. 350-6. FI: 3.978
Epidemiology, diagnosis and treatment of fungal respiratory infections in the critically ill patient.
Garnacho-Montero J, Olaechea P, Alvarez-Lerma F, Alvarez-Rocha L, Blanquer J, Galván B, Rodriguez A, Zaragoza R, Aguado JM, Mensa J, Solé A, Barberán J
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia. 2013 Jun. 173-88. FI: 0.836
Factors related to lymph node harvest: does a recovery of more than 12 improve the outcome of colorectal cancer?
Moro-Valdezate D, Pla-Martí V, Martín-Arévalo J, Belenguer-Rodrigo J, Aragó-Chofre P, Ruiz-Carmona MD, Checa-Ayet F
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2013 Oct. 1257-66. FI: 2.081
Heterogeneous responses of nucleus incertus neurons to corticotrophin-releasing factor and coherent activity with hippocampal theta rhythm in the rat.
Ma S, Blasiak A, Olucha-Bordonau FE, Verberne AJ, Gundlach AL
The Journal of physiology. 2013 Aug 15. 3981-4001. FI: 4.38
High stability of microRNAs in tissue samples of compromised quality.
Peiró-Chova L, Peña-Chilet M, López-Guerrero JA, García-Giménez JL, Alonso-Yuste E, Burgues O, Lluch A, Ferrer-Lozano J, Ribas G
Virchows Archiv : an international journal of pathology. 2013 Dec. 765-74. FI: 2.676
Hypoxia-inducible factor 1 alpha contributes to cardiac healing in mesenchymal stem cells-mediated cardiac repair.
Cerrada I, Ruiz-Saurí A, Carrero R, Trigueros C, Dorronsoro A, Sanchez-Puelles JM, Diez-Juan A, Montero JA, Sepúlveda P
Stem cells and development. 2013 Feb 1. 501-11. FI: 4.67
Increasing Incidence of Hepatocellular Carcinoma in HIV-Infected Patients in Spain.
Merchante N, Merino E, López-Aldeguer J, Jover F, Delgado-Fernández M, Galindo MJ, Ortega E, Rivero A, Mínguez C, Romero-Palacios A, Padilla S, Márquez-Solero M, Amador C, Ríos-Villegas MJ, Téllez F, Portilla J, Pineda JA
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2013 Jan. 143-50. FI: 9.374000000000001
Mesenchymal stromal-cell transplants induce oligodendrocyte progenitor migration and remyelination in a chronic demyelination model.
Jaramillo-Merchán J, Jones J, Ivorra JL, Pastor D, Viso-León MC, Armengól JA, Moltó MD, Geijo-Barrientos E, Martínez S
Cell death & disease. 2013 Aug 29. e779. FI: 6.044
Microbial aetiology of healthcare associated pneumonia in Spain: a prospective, multicentre, case-control study.
Polverino E, Torres A, Menendez R, Cillóniz C, Valles JM, Capelastegui A, Marcos MA, Alfageme I, Zalacain R, Almirall J, Molinos L, Bello S, Rodríguez F, Blanquer J, Dorado A, Llevat N, Rello J, HCAP Study investigators
Thorax. 2013 Nov. 1007-14. FI: 8.375999999999999
Severe Septic Patients with Mitochondrial DNA Haplogroup JT Show Higher Survival Rates: A Prospective, Multicenter, Observational Study.
Lorente L, Iceta R, Martín MM, López-Gallardo E, Solé-Violán J, Blanquer J, Labarta L, Díaz C, Borreguero-León JM, Jiménez A, Montoya J, Ruiz-Pesini E
PloS one. 2013 Sep 12. e73320. FI: 3.73
Sustained high serum malondialdehyde levels are associated with severity and mortality in septic patients.
Lorente L, Martín MM, Abreu P, Domínguez-Rodriguez A, Labarta L, Díaz C, Solé-Violán J, Ferreres J, Cabrera J, Igeño JC, Jiménez A
Critical care (London, England). 2013 Dec 11. R290
The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis.
Lorente L, Martín MM, Plasencia F, Solé-Violán J, Blanquer J, Labarta L, Díaz C, Borreguero-León JM, Jiménez A, Páramo JA, Orbe J, Rodríguez JA, Salido E
Critical care (London, England). 2013 May 25. R94
[Consensus document on vaccination against influenza in health care workers].
Picazo JJ, Alonso LM, Arístegui J, Bayas JM, Sanz J, Del Amo P, Cobos JL, Rodríguez-Salazar J, Sánchez-Pastor M, de la Cámara R, Carratalá J, Cañada JL, González-Del Castillo J, Aldaz P, Pérez-Escanilla F, Barberán J, Rodríguez A, Vigil-Escribano D, Espinosa-Arranz J, Blanquer J, González-Romo F
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia. 2012 Sep. 226-39. FI: 0.836
2009 H1N1: risk factors for hospitalization in a matched case-control study.
Launes C, García-García JJ, Martínez-Planas A, Moraga F, Astigarraga I, Arístegui J, Korta J, Salado C, Quintana JM, Soldevila N, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
European journal of pediatrics. 2012 Jul. 1127-31. FI: 1.907
Bilevel exercise training and directed breathing relieves exertional dyspnea for male smokers.
Gimenez M, Saavedra P, Martin N, Polu JM, López D, Gómez A, Servera E
American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 2012 Oct. 836-45. FI: 1.731
Clinical audit of COPD patients requiring hospital admissions in Spain: AUDIPOC study.
Pozo-Rodríguez F, López-Campos JL, Alvarez-Martínez CJ, Castro-Acosta A, Agüero R, Hueto J, Hernández-Hernández J, Barrón M, Abraira V, Forte A, Sanchez Nieto JM, Lopez-Gabaldón E, Cosío BG, Agustí A, AUDIPOC Study Group
PloS one. 2012. e42156. FI: 3.73
Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza.
Diaz E, Martin-Loeches I, Canadell L, Vidaur L, Suarez D, Socias L, Estella A, Gil Rueda B, Guerrero JE, Valverdú-Vidal M, Vergara JC, López-Pueyo MJ, Magret M, Recio T, López D, Rello J, Rodriguez A, H1N1 SEMICYUC-CIBERES-REIPI Working Group (GETGAG)
The Journal of infection. 2012 Mar. 311-8. FI: 4.073
Effectiveness of hand hygiene and provision of information in preventing influenza cases requiring hospitalization.
Godoy P, Castilla J, Delgado-Rodríguez M, Martín V, Soldevila N, Alonso J, Astray J, Baricot M, Cantón R, Castro A, González-Candelas F, Mayoral JM, Quintana JM, Pumarola T, Tamames S, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Preventive medicine. 2012 Jun. 434-9. FI: 3.496
Effectiveness of pandemic and seasonal influenza vaccines in preventing pandemic influenza-associated hospitalization.
Domínguez A, Castilla J, Godoy P, Delgado-Rodríguez M, Martín V, Saez M, Soldevila N, Quintana JM, Mayoral JM, Astray J, González-Candelas F, Cantón R, Tamames S, Castro A, Baricot M, Alonso J, Pumarola T, CIBERESP Cases and Controls in Pandemic Influenza Working Group Spain
Vaccine. 2012 Aug 17. 5644-50. FI: 3.492
Hypocapnia and hypercapnia are predictors for ICU admission and mortality in hospitalized patients with community-acquired pneumonia.
Laserna E, Sibila O, Aguilar PR, Mortensen EM, Anzueto A, Blanquer JM, Sanz F, Rello J, Marcos PJ, Velez MI, Aziz N, Restrepo MI
Chest. 2012 Nov. 1193-9. FI: 5.854
Prognosis of hospitalized patients with 2009 H1N1 influenza in Spain: influence of neuraminidase inhibitors.
Delgado-Rodríguez M, Castilla J, Godoy P, Martín V, Soldevila N, Alonso J, Astray J, Baricot M, Cantón R, Castro A, Gónzález-Candelas F, Mayoral JM, Quintana JM, Pumarola T, Tamames S, Sáez M, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group
The Journal of antimicrobial chemotherapy. 2012 Jul. 1739-45. FI: 5.338
Roflumilast N-oxide, a PDE4 inhibitor, improves cilia motility and ciliated human bronchial epithelial cells compromised by cigarette smoke in vitro.
Milara J, Armengot M, Bañuls P, Tenor H, Beume R, Artigues E, Cortijo J
British journal of pharmacology. 2012 Aug. 2243-62. FI: 5.067
Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission.
Capelastegui A, Quintana JM, Bilbao A, España PP, Garin O, Alonso J, Astray J, Cantón R, Castilla J, Castro A, Delgado-Rodríguez M, Godoy P, Gónzález-Candelas F, Martín V, Mayoral JM, Pumarola T, Tamames S, Soldevila N, Baricot M, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2012 Oct. 2693-701. FI: 3.024
Sociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009-2010.
González-Candelas F, Astray J, Alonso J, Castro A, Cantón R, Galán JC, Garin O, Sáez M, Soldevila N, Baricot M, Castilla J, Godoy P, Delgado-Rodríguez M, Martín V, Mayoral JM, Pumarola T, Quintana JM, Tamames S, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group
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Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup.
Lorente L, Iceta R, Martín MM, López-Gallardo E, Solé-Violán J, Blanquer J, Labarta L, Díaz C, Jiménez A, Montoya J, Ruiz-Pesini E
Critical care (London, England). 2012 Jan 17. R10. FI: 4.607
Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia.
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Intensive care medicine. 2012 Feb. 256-62. FI: 5.258

Efecto del cigarrillo electrónico (propilenglicol, dietilenglicol y nicotina) sobre la función pulmonar y la inflamación sistémica: estudios de toxicidad y activación leucocitaria en diferentes subpoblaciones de células circulantes inmunitarias. Medida de

Referencia:
SIN EXPEDIENTE 88
Investigador principal:
(María Jesús Sanz y Emilio Servera as collaborating researcher)
Entidad financiadora:
Sociedad Valenciana de Neumología/ Fundación de Neumología De La Comunidad Valenciana.
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€6.000

Physiological and clinical effectiveness of mechanically assited coughing techniques using cough assist with oscillations in amyotrophic lateral sclerosis patients.

Referencia:
SIN EXPEDIENTE 86
Investigador principal:
Emilio Servera
Entidad financiadora:
Phillips Respironics
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€80.000

Estudio fisiopatológico de las causas de ventilación mecánica no invasiva en los pacientes con esclerosis lateral amiotrófica

Referencia:
Phillips Respironics 1
Investigador principal:
Jesús Sancho Chinesta
Entidad financiadora:
Phillips Respironics
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€0

Apego, acontecimientos vitales estresantes y duelo.

Referencia:
PSI 2014-51962-R
Investigador principal:
Pilar Barreto Martín / María Antonia Pérez Marín
Entidad financiadora:
Ministerio de Economía y Competitividad
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€72.600

Valoración de la demencia frontotemporal y su repercusión en el proceso de toma de decisiones terapéuticas en pacientes con esclerosis lateral amiotrófica.

Referencia:
INCLIVA 10
Investigador principal:
Emilio Servera Pieras
Entidad financiadora:
INCLIVA
Duración:
01/01/2015 - 31/12/2015
Presupuesto total:
€4.000

Control sintomático en pacientes con necesidades de atención paliativa y espiritualidad. Análisis descriptivo y modelos de relación. Estudio multicéntrico

Referencia:
PCC-11/13
Investigador principal:
Miguel Fombuena Moreno
Entidad financiadora:
Generalitat Valenciana. Conselleria de Sanitat
Duración:
01/01/2013 - 31/12/2013
Presupuesto total:
€0

Un estudio de investigadores de INCLIVA permite predecir qué personas con ELA no serán capaces de toser de forma efectiva

Publicados los resultados de un proyecto de la Unidad de Cuidados Respiratorios sobre la ELA.

Publicado el 13/07/2017.Leer más »