Área Metabolismo

Grupo de Investigación en Envejecimiento y Ejercicio Físico

José Viña Ribes

El Dr. José Viña Ribes es Catedrático de Fisiología de la Universitat de València. Tras finalizar sus estudios en medicina en esta universidad, se inició en la investigación biomédica en la Universidad de Oxford, en el Medical Research Council (Consejo de Investigación Médica), bajo la dirección del Prof. Hans Krebs, obteniendo el título de doctor en 1976.

El profesor Viña es Doctor ‘honoris causa’ por la Université de Rennes 2 en Francia a propuesta del profesor Paul Delamarche, decano de la Facultad de Educación Física. También ha sido nombrado Doctor ‘honoris causa’ por la Universidad Argentina de Buenos Aires.

El Dr. Viña ha centrado sus investigaciones en el envejecimiento y los radicales libres, las enfermedades asociadas al envejecimiento como la enfermedad de Alzheimer, las alteraciones metabólicas durante el envejecimiento y la fragilidad asociada al mismo. En la actualidad investiga los genes específicos que expresan las personas centenarias y su regulación mediante dieta y ejercicio. Es el Director de la Línea de Investigación de Metabolismo y Daño Orgánico - envejecimiento y enfermedades asociadas de la Fundación INCLIVA.

 

Grupo de investigación en envejecimiento y ejercicio físico

Investigador colaborador

Andrea Salvador Pascual
Marta Inglés de la Torre
Gloria Olaso González
Consuelo Escriva López
Esther Giraldo Reboloso

Investigador predoctoral

José Viña Almunia
Helena Cabo Plaza
Cristina Mas Bargues

Línea de investigación del Alzheimer:

  • Descubrimiento de una vía de excitotoxicidad por glutamato debido al aumento de los niveles de glutaminasa.

 Línea de investigación de Ejercicio Físico:

  • Demostración del papel protector del ejercicio  físico en el tratamiento de la sarcopenia senil, así como las bases moleculares que sustentan dicha mejora 
  • Establecimiento de pautas de prescripción de ejercicio físico en la población anciana.
  • Demostración del papel protector del alopurinol en el daño muscular asociado a la práctica  del fútbol profesional.

Línea de investigación de envejecimiento:

  • Constitución grupo español para el estudio de Centenarios.
  • Publicación de la revisión de la teoría de los radicales libres del envejecimiento
Número total de publicaciones: 157. Factor de Impacto acumulado: 720.59
Olympic Genes on the Podium?
Sanchis-Gomar F, Galeano HP, Rodriguez-Marroyo JA, de Koning JJ, Lucia A, Foster C
International journal of sports physiology and performance.. 2016 Oct 13. 42583. FI: 3.042
Influence of different types of pulp treatment during isolation in the obtention of human dental pulp stem cells.
Viña-Almunia J, Borras C, Gambini J, El Alamy M, Peñarrocha M, Viña J
Medicina oral, patología oral y cirugía bucal.. 2016 May 1. e374-9
Reductive Stress: A New Concept in Alzheimer's Disease.
Lloret A, Fuchsberger T, Giraldo E, Vina J
Current Alzheimer research.. 2016. 206-11. FI: 3.889
PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA
Nature neuroscience.. 2016 Mar. 443-53. FI: 16.095
Role of NAD(+)/NADH redox ratio in cell metabolism: A tribute to Helmut Sies and Theodor Bücher and Hans A. Krebs.
Viña J, Saez GT, Gambini J, Gomez-Cabrera MC, Borrás C
Archives of biochemistry and biophysics.. 2016 Apr 1. 176-80. FI: 3.017
Editorial Olympic 2016 Special Issue "Human performance and redox signaling in health and disease".
Viña J, Gomez-Cabrera MC, J Jackson M
Free radical biology & medicine.. 2016 Jun 6. . FI: 5.784
Disinfection by-products effect on swimmers oxidative stress and respiratory damage.
Llana-Belloch S, Priego Quesada JI, Pérez-Soriano P, Lucas-Cuevas ÁG, Salvador-Pascual A, Olaso-González G, Moliner-Martinez Y, Verdú-Andres J, Campins-Falco P, Gómez-Cabrera MC
European journal of sport science. 2016 Aug. 609-17. FI: 1.55
Biology of frailty: Modulation of ageing genes and its importance to prevent age-associated loss of function.
Viña J, Tarazona-Santabalbina FJ, Pérez-Ros P, Martínez-Arnau FM, Borras C, Olaso-Gonzalez G, Salvador-Pascual A, Gomez-Cabrera MC
Molecular aspects of medicine.. 2016 May 6. . FI: 10.238
Brain-Derived Neurotrophic Factor as a Marker of Cognitive Frailty.
Inglés M, Gambini J, Mas-Bargues C, García-García FJ, Viña J, Borrás C
The journals of gerontology. Series A, Biological sciences and medical sciences.. 2016 Jul 22. . FI: 5.476
Autoantibodies Profile in Matching CSF and Serum from AD and aMCI patients: Potential Pathogenic Role and Link to Oxidative Damage.
Di Domenico F, Pupo G, Giraldo E, Lloret A, Badia MC, Schinina ME, Giorgi A, Butterfield DA, Vina J, Perluigi M
Current Alzheimer research.. 2016. 112-22. FI: 3.889
Atrial fibrillation in highly trained endurance athletes - Description of a syndrome.
Sanchis-Gomar F, Perez-Quilis C, Lippi G, Cervellin G, Leischik R, Löllgen H, Serrano-Ostáriz E, Lucia A
International journal of cardiology.. 2016 Oct 19. 44136. FI: 4.638
Clearing Amyloid-? through PPAR?/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer's Disease.
Bonet-Costa V, Herranz-Pérez V, Blanco-Gandía M, Mas-Bargues C, Inglés M, Garcia-Tarraga P, Rodriguez-Arias M, Miñarro J, Borras C, Garcia-Verdugo JM, Viña J
Journal of Alzheimer's disease: JAD.. 2016 Feb 10. 701-11. FI: 4.151
Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.
Traylor M, Zhang CR, Adib-Samii P, Devan WJ, Parsons OE, Lanfranconi S, Gregory S, Cloonan L, Falcone GJ, Radmanesh F, Fitzpatrick K, Kanakis A, Barrick TR, Moynihan B, Lewis CM, Boncoraglio GB, Lemmens R, Thijs V, Sudlow C, Wardlaw J, Rothwell PM, Meschia JF, Worrall BB, Levi C, Bevan S, Furie KL, Dichgans M, Rosand J, Markus HS, Rost N, International Stroke Genetics Consortium
Neurology.. 2016 Jan 12. 146-53. FI: 8.286
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
GBD 2015 Risk Factors Collaborators.
Lancet.. 2016 Oct 8. 1659-1724. FI: 44.002
Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging.
Borras C, Abdelaziz KM, Gambini J, Serna E, Inglés M, de la Fuente M, Garcia I, Matheu A, Sanchís P, Belenguer A, Errigo A, Avellana JA, Barettino A, Lloret-Fernández C, Flames N, Pes G, Rodriguez-Mañas L, Viña J
Aging. 2016 Oct 28. . FI: 3.979
ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups.
Brodaty H, Woolf C, Andersen S, Barzilai N, Brayne C, Cheung KS, Corrada MM, Crawford JD, Daly C, Gondo Y, Hagberg B, Hirose N, Holstege H, Kawas C, Kaye J, Kochan NA, Lau BH, Lucca U, Marcon G, Martin P, Poon LW, Richmond R, Robine JM, Skoog I, Slavin MJ, Szewieczek J, Tettamanti M, Viña J, Perls T, Sachdev PS
BMC neurology. 2016 Apr 21. 52. FI: 2.04
In Search of 'Omics'-Based Biomarkers to Predict Risk of Frailty and Its Consequences in Older Individuals: The FRAILOMIC Initiative.
Erusalimsky JD, Grillari J, Grune T, Jansen-Duerr P, Lippi G, Sinclair AJ, Tegnér J, Viña J, Durrance-Bagale A, Miñambres R, Viegas M, Rodríguez-Mañas L, FRAILOMIC Consortium
Gerontology.. 2016. 182-90. FI: 3.059
Endocrinology of Aging From a Muscle Function Point of View: Results From the Toledo Study for Healthy Aging.
Guadalupe-Grau A, Carnicero JA, Losa-Reyna J, Tresguerres J, Gómez-Cabrera MD, Castillo C, Alfaro-Acha A, Rosado-Artalejo C, Rodriguez-Mañas L, García-García FJ
Journal of the American Medical Directors Association.. 2016 Oct 21. . FI: 6.616
G6PD protects from oxidative damage and improves healthspan in mice.
Nóbrega-Pereira S, Fernandez-Marcos PJ, Brioche T, Gomez-Cabrera MC, Salvador-Pascual A, Flores JM, Viña J, Serrano M
Nature communications. 2016 Mar 15. 10894. FI: 11.47
Exercise training as a drug to treat age associated frailty.
Viña J, Salvador-Pascual A, Tarazona-Santabalbina FJ, Rodriguez-Mañas L, Gomez-Cabrera MC
Free radical biology & medicine.. 2016 Mar 25. . FI: 5.736
Exercise: the lifelong supplement for healthy ageing and slowing down the onset of frailty.
Viña J, Rodriguez-Mañas L, Salvador-Pascual A, Tarazona-Santabalbina FJ, Gomez-Cabrera MC
The Journal of physiology.. 2016 Apr 15. 1989-99. FI: 5.037
[Identification of single nucleotide polymorphisms in centenarians].
Gambini J, Gimeno-Mallench L, Inglés M, Olaso G, Abdelaziz KM, Avellana JA, Belenguer Á, Cruz R, Mas-Bargues C, Borras C, Viña J
Revista española de geriatría y gerontología.. 2016 May-Jun. 146-9
A Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival.
Fuchsberger T, Martínez-Bellver S, Giraldo E, Teruel-Martí V, Lloret A, Viña J
Scientific reports.. 2016 Aug 12. 31158. FI: 5.228
A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial.
Tarazona-Santabalbina FJ, Gómez-Cabrera MC, Pérez-Ros P, Martínez-Arnau FM, Cabo H, Tsaparas K, Salvador-Pascual A, Rodriguez-Mañas L, Viña J
Journal of the American Medical Directors Association.. 2016 May 1. 426-33. FI: 4.939
A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans.
Jové M, Naudí A, Gambini J, Borras C, Cabré R, Portero-Otín M, Viña J, Pamplona R
The journals of gerontology. Series A, Biological sciences and medical sciences.. 2016 Mar 24. . FI: 5.416
Active paraplegics are protected against exercise-induced oxidative damage through the induction of antioxidant enzymes.
Inglés M, Serra-Añó P, Gambini J, Abu-Sharif F, Dromant M, Garcia-Valles R, Pareja-Galeano H, Garcia-Lucerga C, Gomez-Cabrera MC
Spinal cord.. 2016 Feb 16. . FI: 1.804
[Oxidative stress and longevity; a case-control study].
Belenguer Varea Á, Mohamed Abdelaziz K, Avellana Zaragoza JA, Borrás Blasco C, Sanchis Aguilar P, Viña Ribes J
Revista española de geriatría y gerontología.. 2015 Jan-Feb. 16-21
Allopurinol prevents cardiac and skeletal muscle damage in professional soccer players.
Sanchis-Gomar F, Pareja-Galeano H, Gomez-Cabrera MC, Candel J, Lippi G, Salvagno GL, Mann GE, Viña J
Scandinavian journal of medicine & science in sports. 2015 Feb. e110-5. FI: 2.896
Effect of exhaustive running exercise on red blood cell distribution width.
Alis R, Romagnoli M, Primo-Carrau C, Pareja-Galeano H, Blesa JR, Sanchis-Gomar F
Clinical chemistry and laboratory medicine : CCLM / FESCC. 2015 Feb 1. e29-31. FI: 2.707
Effects of allopurinol on exercise-induced muscle damage: new therapeutic approaches?
Sanchis-Gomar F, Pareja-Galeano H, Perez-Quilis C, Santos-Lozano A, Fiuza-Luces C, Garatachea N, Lippi G, Lucia A
Cell stress & chaperones. 2015 Jan. 41334. FI: 3.163
Effects of an acute high-intensity interval training protocol on plasma viscosity.
Alis R, Ibañez-Sania S, Basterra J, Sanchis-Gomar F, Romagnoli M
The Journal of sports medicine and physical fitness. 2015 Jun. 647-53. FI: 0.972
Even free radicals should follow some rules: A Guide to free radical research terminology and methodology.
Forman HJ, Augusto O, Brigelius-Flohe R, Dennery PA, Kalyanaraman B, Ischiropoulos H, Mann GE, Radi R, Roberts LJ 2nd, Vina J, Davies KJ
Free radical biology & medicine. 2015 Jan. 233-5. FI: 5.736
Hemoconcentration induced by exercise: Revisiting the Dill and Costill equation.
Alis R, Sanchis-Gomar F, Primo-Carrau C, Lozano-Calve S, Dipalo M, Aloe R, Blesa JR, Romagnoli M, Lippi G
Scandinavian journal of medicine & science in sports.. 2015 Dec. e630-7. FI: 2.896
Laboratory biomarkers and frailty: presentation of the FRAILOMIC initiative.
Lippi G, Jansen-Duerr P, Viña J, Durrance-Bagale A, Abugessaisa I, Gomez-Cabrero D, Tegnér J, Grillari J, Erusalimsky J, Sinclair A, Rodriguez-Manãs L, FRAILOMIC consortium
Clinical chemistry and laboratory medicine.. 2015 Sep 1. e253-5. FI: 2.707
Methodological considerations to determine the effect of exercise on brain-derived neurotrophic factor levels.
Pareja-Galeano H, Alis R, Sanchis-Gomar F, Cabo H, Cortell-Ballester J, Gomez-Cabrera MC, Lucia A, Viña J
Clinical biochemistry. 2015 Feb. 162-6. FI: 2.275
Molecular mechanisms linking amyloid toxicity and Tau hyperphosphorylation in Alzheimers disease.
Lloret A, Fuchsberger T, Giraldo E, Viña J
Free radical biology & medicine. 2015 Mar 5. 186-191. FI: 5.736
Oxidant antioxidants and adaptive responses to exercise.
Venditti P, Gomez-Cabrera MC, Zhang Y, Radak Z
Oxidative medicine and cellular longevity. 2015. 290190. FI: 3.516
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients.
Di Domenico F, Pupo G, Giraldo E, Badìa MC, Monllor P, Lloret A, Eugenia Schininà M, Giorgi A, Cini C, Tramutola A, Butterfield DA, Viña J, Perluigi M
Free radical biology & medicine.. 2015 Dec 8. 42614. FI: 5.736
Physical activity and depression: type of exercise matters.
Pareja-Galeano H, Sanchis-Gomar F, Lucia A
JAMA pediatrics. 2015 Mar 1. 288-9. FI: 7.148
Physical inactivity and low fitness deserve more attention to alter cancer risk and prognosis.
Sanchis-Gomar F, Lucia A, Yvert T, Ruiz-Casado A, Pareja-Galeano H, Santos-Lozano A, Fiuza-Luces C, Garatachea N, Lippi G, Bouchard C, Berger NA
Cancer prevention research (Philadelphia, Pa.). 2015 Feb. 105-10. FI: 4.444
Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans.
Gambini J, Inglés M, Olaso G, Lopez-Grueso R, Bonet-Costa V, Gimeno-Mallench L, Mas-Bargues C, Abdelaziz KM, Gomez-Cabrera MC, Vina J, Borras C
Oxidative medicine and cellular longevity. 2015. 837042. FI: 3.516
Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?
Gomez-Cabrera MC, Salvador-Pascual A, Cabo H, Ferrando B, Viña J
Free radical biology & medicine.. 2015 Sep. 37-46. FI: 5.736
Response to vidal and colleagues.
Viña J, Inglés M, Borrás C
Journal of the American Geriatrics Society. 2015 Apr. 838-9. FI: 4.572
Serum Copeptin and Midregion Proadrenomedullin (MR-proADM) After an Ultramarathon.
Lippi G, Schena F, Salvagno GL, Sanchis-Gomar F, Guidi GC
Journal of clinical laboratory analysis. 2015 Jan. 15-20. FI: 1.038
Strenuous endurance exercise and right ventricular systolic function: no evidence of long-term sequelae.
Sanchis-Gomar F, Garatachea N, Catalán P, López M, Lucia A, Serrano-Ostáriz E
International journal of cardiology. 2015 Jan 20. 297-8. FI: 4.036
[Allopurinol and its role in the treatment of sarcopenia].
Ferrando B, Olaso-Gonzalez G, Sebastia V, Viosca E, Gomez-Cabrera MC, Viña J
Revista española de geriatría y gerontología. 2014 Nov-Dec. 292-8
[Prevalence of sarcopenia in geriatric outpatients and nursing homes. The ELLI study].
Osuna-Pozo CM, Serra-Rexach JA, Viña J, Gómez-Cabrera Mdel C, Salvá A, Ruiz D, Masanes F, Lopez-Soto A, Formiga F, Cuesta F, Cruz-Jentoft A
Revista española de geriatría y gerontología. 2014 Mar-Apr. 72-6
A? and tau toxicities in Alzheimer's are linked via oxidative stress-induced p38 activation: protective role of vitamin E.
Giraldo E, Lloret A, Fuchsberger T, Viña J
Redox biology. 2014. 873-7
Acetaminophen and sport performance: doping or what?
Lippi G, Sanchis-Gomar F
European journal of applied physiology. 2014 Apr. 881-2. FI: 2.298
Activation of p38, p21, and NRF-2 Mediates Decreased Proliferation of Human Dental Pulp Stem Cells Cultured under 21% O2.
El Alami M, Viña-Almunia J, Gambini J, Mas-Bargues C, Siow RC, Peñarrocha M, Mann GE, Borrás C, Viña J
Stem cell reports. 2014 Oct 14. 566-73
Altitude exposure in sports: the Athlete Biological Passport standpoint.
Sanchis-Gomar F, Pareja-Galeano H, Brioche T, Martinez-Bello V, Lippi G
Drug testing and analysis. 2014 Mar. 190-3. FI: 2.816
Application of mesenchymal stem cells in bone regenerative procedures in oral implantology. A literature review.
Viña JA, El-Alami M, Gambini J, Borras C, Viña J, Peñarrocha MA
Academic medicine : journal of the Association of American Medical Colleges. 2014 Feb. e60-e65
Association between irisin and homocysteine in euglycemic and diabetic subjects.
Alis R, Sanchis-Gomar F, Pareja-Galeano H, Hernández-Mijares A, Romagnoli M, Víctor VM, Rocha M
Clinical biochemistry. 2014 Dec. 333-5. FI: 2.229
Biological markers in older people at risk of mobility limitations.
Lippi G, Sanchis-Gomar F, Montagnana M
Current pharmaceutical design. 2014. 3222-44. FI: 3.288
Blood rheology effect of submaximal exercise on young subjects.
Romagnoli M, Alis R, Martinez-Bello V, Sanchis-Gomar F, Aranda R, Gómez-Cabrera MC
Clinical hemorheology and microcirculation. 2014 Jan 1. 111-7. FI: 2.215
Circulating irisin levels are not correlated with BMI, age, and other biological parameters in obese and diabetic patients.
Sanchis-Gomar F, Alis R, Pareja-Galeano H, Sola E, Victor VM, Rocha M, Hernández-Mijares A, Romagnoli M
Endocrine. 2014 Aug. 674-7. FI: 3.527
Correcting loss of a papilla following orthodontic space opening (Atherton´s patch) through implant supported rehabilitation. A case report.
Viña J, Balaguer J, Martorell L, Peñarrocha M
Academic medicine : journal of the Association of American Medical Colleges. 2014 Feb. e100-3
Early, but not late onset estrogen replacement therapy prevents oxidative stress and metabolic alterations caused by ovariectomy.
López-Grueso R, Gambini J, Abdelaziz KM, Monleón D, Díaz A, El Alami M, Bonet-Costa V, Borrás C, Viña J
Antioxidants & redox signaling. 2014 Jan 10. 236-46. FI: 7.667
Elite athletes live longer than the general population: a meta-analysis.
Garatachea N, Santos-Lozano A, Sanchis-Gomar F, Fiuza-Luces C, Pareja-Galeano H, Emanuele E, Lucia A
Mayo Clinic proceedings. Mayo Clinic. 2014 Sep. 1195-200. FI: 5.812
Exome sequencing of three cases of familial exceptional longevity.
Cash TP, Pita G, Domínguez O, Alonso MR, Moreno LT, Borrás C, Rodríguez-Mañas L, Santiago C, Garatachea N, Lucia A, Avellana JA, Viña J, González-Neira A, Serrano M
Aging cell. 2014 Dec. 1087-90. FI: 5.939
FORUM ISSUE: "Free radicals and physical exercise".
Vina J, Gomez-Cabrera MC
Free radical research. 2014 Jan. 42036. FI: 2.989
Growth hormone replacement therapy prevents sarcopenia by a dual mechanism: improvement of protein balance and of antioxidant defenses.
Brioche T, Kireev RA, Cuesta S, Gratas-Delamarche A, Tresguerres JA, Gomez-Cabrera MC, Viña J
The journals of gerontology. Series A, Biological sciences and medical sciences. 2014 Oct. 1186-98. FI: 4.984
How does the journal impact factor affect the CV of PhD students?
Sanchis-Gomar F
EMBO reports. 2014 Mar. 207. FI: 7.858
Immunoglobulin E (IgE) and ischemic heart disease. Which came first, the chicken or the egg?
Lippi G, Cervellin G, Sanchis-Gomar F
Annals of medicine. 2014 Nov. 456-63. FI: 4.733
Inactivity-induced oxidative stress: a central role in age-related sarcopenia?
Derbré F, Gratas-Delamarche A, Gómez-Cabrera MC, Viña J
European journal of sport science. 2014. S98-108. FI: 1.314
Decreased cell proliferation and higher oxidative stress in fibroblasts from Down Syndrome fetuses. Preliminary study.
Gimeno A, García-Giménez JL, Audí L, Toran N, Andaluz P, Dasí F, Viña J, Pallardó FV
Biochimica et biophysica acta. 2014 Jan. 116-25
Influence of occlusal loading on peri-implant clinical parameters. A pilot study.
Pellicer-Chover H, Viña-Almunia J, Romero-Millán J, Peñarrocha-Oltra D, García-Mira B, Peñarrocha-Diago MA
Medicina oral, patología oral y cirugía bucal. 2014 May 1. e302-7
Influence of training and a maximal exercise test in analytical variability of muscular, hepatic, and cardiovascular biochemical variables.
Romagnoli M, Alis R, Aloe R, Salvagno GL, Basterra J, Pareja-Galeano H, Sanchis-Gomar F, Lippi G
Scandinavian journal of clinical and laboratory investigation. 2014 Apr. 192-8. FI: 2.009
Inhibition of xanthine oxidase and exercise on serum uric acid, 25(OH)D3, and calcium concentrations.
Sanchis-Gomar F, Salvagno GL, Lippi G
Clinical laboratory. 2014. 1409-11. FI: 1.084
Melatonin and oestrogen treatments were able to improve neuroinflammation and apoptotic processes in dentate gyrus of old ovariectomized female rats.
Kireev RA, Vara E, Viña J, Tresguerres JA
Age (Dordrecht, Netherlands). 2014 Oct. 9707. FI: 3.445
Metabolomic analysis of long-term spontaneous exercise in mice suggests increased lipolysis and altered glucose metabolism when animals are at rest.
Monleon D, Garcia-Valles R, Morales JM, Brioche T, Olaso-Gonzalez G, Lopez-Grueso R, Gomez-Cabrera MC, Viña J
Journal of applied physiology (Bethesda, Md. : 1985). 2014 Nov 15. 1110-9. FI: 3.434
Erythropoietin and the heart: Physiological effects and the therapeutic perspective.
Sanchis-Gomar F, Garcia-Gimenez JL, Pareja-Galeano H, Romagnoli M, Perez-Quilis C, Lippi G
International journal of cardiology. 2014 Feb 1. 116-25. FI: 6.175
Inconsistency in circulating irisin levels: what is really happening?
Sanchis-Gomar F, Alis R, Pareja-Galeano H, Romagnoli M, Perez-Quilis C
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme. 2014 Jul. 591-6. FI: 2.038
Mitochondrial biogenesis in health and disease. Molecular and therapeutic approaches.
Sanchis-Gomar F, Garcia-Gimenez JL, Gomez-Cabrera MC, Pallardo FV
Current pharmaceutical design. 2014. 5619-33. FI: 3.288
Mitochondrial fission and fusion in human diseases.
Sanchis-Gomar F, Derbré F
The New England journal of medicine. 2014 Mar 13. 1073-4. FI: 54.42
New molecular targets and lifestyle interventions to delay aging sarcopenia.
Sanchis-Gomar F, Pareja-Galeano H, Mayero S, Perez-Quilis C, Lucia A
Frontiers in aging neuroscience. 2014. 156. FI: 2.843
'Olympic' centenarians: Are they just biologically exceptional?
Sanchis-Gomar F, Pareja-Galeano H, Lucía A
International journal of cardiology. 2014 Jul 15. 216-7. FI: 6.175
Oxidative stress is related to frailty, not to age or sex, in a geriatric population: lipid and protein oxidation as biomarkers of frailty.
Inglés M, Gambini J, Carnicero JA, García-García FJ, Rodríguez-Mañas L, Olaso-González G, Dromant M, Borrás C, Viña J
Journal of the American Geriatrics Society. 2014 Jul. 1324-8. FI: 4.216
Pharmacological properties of physical exercise in the elderly.
Vina J, Borras C, Sanchis-Gomar F, Martinez-Bello VE, Olaso-Gonzalez G, Gambini J, Ingles M, Gomez-Cabrera MC
Current pharmaceutical design. 2014. 3019-29. FI: 3.288
Physical activity - an important preanalytical variable.
Sanchis-Gomar F, Lippi G
Biochemia medica : ?asopis Hrvatskoga društva medicinskih biokemi?ara / HDMB. 2014. 68-79. FI: 2.4
Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms.
García-Mesa Y, Pareja-Galeano H, Bonet-Costa V, Revilla S, Gómez-Cabrera MC, Gambini J, Giménez-Llort L, Cristòfol R, Viña J, Sanfeliu C
Psychoneuroendocrinology. 2014 Jul. 154-66. FI: 5.591
PPARgamma agonist pioglitazone does not enhance performance in mice.
Sanchis-Gomar F, Pareja-Galeano H, Martinez-Bello VE
Drug testing and analysis. 2014 Sep. 922-9. FI: 2.816
Prevention of acute skeletal muscle wasting in critical illness.
Sanchis-Gomar F, Pareja-Galeano H, Cortell-Ballester J, Perez-Quilis C
Minerva anestesiologica. 2014 Jun. 748. FI: 2.272
Protective effect of trehalose-loaded liposomes against UVB-induced photodamage in human keratinocytes.
Emanuele E, Bertona M, Sanchis-Gomar F, Pareja-Galeano H, Lucia A
Biomedical reports. 2014 Sep. 755-759
PTEN mediates the antioxidant effect of resveratrol at nutritionally relevant concentrations.
Inglés M, Gambini J, Miguel MG, Bonet-Costa V, Abdelaziz KM, El Alami M, Viña J, Borrás C
BioMed research international. 2014. 580852
PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study.
Garatachea N, Fuku N, He ZH, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Venturini L, Santiago C, Santos-Lozano A, Rodríguez G, Ricevuti G, Pareja-Galeano H, Sanchis-Gomar F, Emanuele E, Hirose N, Lucia A
Rejuvenation research. 2014 Oct. 430-8. FI: 3.931
Roles of sedentary aging and lifelong physical activity in exchange of glutathione across exercising human skeletal muscle.
Nyberg M, Mortensen SP, Cabo H, Gomez-Cabrera MC, Viña J, Hellsten Y
Free radical biology & medicine. 2014 May 22. 166-173. FI: 5.71
Serum irisin levels, precocious myocardial infarction, and healthy exceptional longevity.
Emanuele E, Minoretti P, Pareja-Galeano H, Sanchis-Gomar F, Garatachea N, Lucia A
The American journal of medicine. 2014 Sep. 888-90. FI: 5.302
Strenuous exercise and the heart: Are we not seeing the wood for the trees?
Sanchis-Gomar F, Pareja-Galeano H, Santos-Lozano A, Fiuza-Luces C, Garatachea N, Lucia A
International journal of cardiology. 2014 Oct 20. 1304-5. FI: 6.175
The hMTH1 paradox: antioxidants recommended in cancer?
Sanchis-Gomar F, Pareja-Galeano H, Lucía A
DNA repair. 2014 Sep. 163-4. FI: 3.362
Physical exercise and epigenetic modulation: elucidating intricate mechanisms.
Pareja-Galeano H, Sanchis-Gomar F, García-Giménez JL
Sports medicine (Auckland, N.Z.). 2014 Apr. 429-36. FI: 5.32
The p38-PGC-1?-irisin-betatrophin axis: Exploring new pathways in insulin resistance.
Sanchis-Gomar F, Perez-Quilis C
Adipocyte. 2014 Jan 1. 67-8
Anemia, heart failure and exercise training.
Sanchis-Gomar F, Banfi G, Pareja-Galeano H, Martinez-Bello V, Lippi G
International journal of cardiology. 2013 May 25. 587-8. FI: 5.509
Antiplatelet therapy in marathon runners: more harm than benefits?
Lippi G, Sanchis-Gomar F, Cervellin G
The American journal of medicine. 2013 Mar. e19. FI: 4.768
Association between WHO cut-offs for childhood overweight and obesity and cardiometabolic risk.
de Onis M, Martínez-Costa C, Núñez F, Nguefack-Tsague G, Montal A, Brines J
Public health nutrition. 2013 Apr. 625-30. FI: 2.25
Biological Markers in Older People at Risk of Mobility Limitations.
Lippi G, Sanchis-Gomar F, Montagnana M
Current pharmaceutical design. 2013 Sep 18. . FI: 3.311
Efficacy of combination therapy with angiotensin-converting enzyme inhibitor and calcium channel blocker in hypertension.
Redón J, Trenkwalder PR, Barrios V
Expert opinion on pharmacotherapy. 2013 Feb. 155-64. FI: 2.86
Endothelial dysfunction in morbid obesity.
Mauricio MD, Aldasoro M, Ortega J, Vila JM
Current pharmaceutical design. 2013. 5718-29. FI: 3.311
Erythropoietin Receptor (EpoR) Agonism Is Used to Treat a Wide Range of Disease.
Sanchis-Gomar F, Perez-Quilis C, Lippi G
Molecular medicine (Cambridge, Mass.). 2013 Apr 30. 62-4. FI: 4.469
Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068.
Yan Y, Serra V, Prudkin L, Scaltriti M, Murli S, Rodríguez O, Guzman M, Sampath D, Nannini M, Xiao Y, Wagle MC, Wu JQ, Wongchenko M, Hampton G, Ramakrishnan V, Lackner MR, Saura C, Roda D, Cervantes A, Tabernero J, Patel P, Baselga J
Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Dec 15. 6976-86. FI: 7.837
Exercise as an adjuvant intervention in opiate dependence.
Pareja-Galeano H, Sanchis-Gomar F, Mayero S
Substance abuse : official publication of the Association for Medical Education and Research in Substance Abuse. 2013 Apr-Jun. 87-8. FI: 1.245
Growth Hormone Replacement Therapy Prevents Sarcopenia by a Dual Mechanism: Improvement of Protein Balance and of Antioxidant Defenses.
Brioche T, Kireev RA, Cuesta S, Gratas-Delamarche A, Tresguerres JA, Gomez-Cabrera MC, Viña J
The journals of gerontology. Series A, Biological sciences and medical sciences. 2013 Dec 3. . FI: 4.314
Hemoglobin Point-of-Care Testing: The HemoCue System.
Sanchis-Gomar F, Cortell-Ballester J, Pareja-Galeano H, Banfi G, Lippi G
Journal of laboratory automation. 2013 Jun. 198-205. FI: 1.457
Histone h3 glutathionylation in proliferating Mammalian cells destabilizes nucleosomal structure.
García-Giménez JL, Olaso G, Hake SB, Bönisch C, Wiedemann SM, Markovic J, Dasí F, Gimeno A, Pérez-Quilis C, Palacios O, Capdevila M, Viña J, Pallardó FV
Antioxidants & redox signaling. 2013 Oct 20. 1305-20. FI: 7.189
Human leukocyte/endothelial cell interactions and mitochondrial dysfunction in type 2 diabetic patients and their association with silent myocardial ischemia.
Hernandez-Mijares A, Rocha M, Rovira-Llopis S, Bañuls C, Bellod L, de Pablo C, Alvarez A, Roldan-Torres I, Sola-Izquierdo E, Victor VM
Diabetes care. 2013 Jun. 1695-702. FI: 7.735
Hypoxic macrophages impair autophagy in epithelial cells through Wnt1: relevance in IBD.
Ortiz-Masiá D, Cosín-Roger J, Calatayud S, Hernández C, Alós R, Hinojosa J, Apostolova N, Alvarez A, Barrachina MD
Mucosal immunology. 2013 Dec 4. . FI: 7
In vivo strategies for drug discovery in myotonic dystrophy disorders.
Garcia-Alcover I, López Castel A, Perez-Alonso M, Artero R
Drug discovery today. Technologies. 2013 Spring. e97-102
Intravenous busulfan and melphalan as a conditioning regimen for autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: a matched comparison to a melphalan-only approach.
Blanes M, Lahuerta JJ, González JD, Ribas P, Solano C, Alegre A, Bladé J, San Miguel JF, Sanz MA, de la Rubia J
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2013 Jan. 69-74. FI: 3.94
Sugammadex, a neuromuscular blockade reversal agent, causes neuronal apoptosis in primary cultures.
Palanca JM, Aguirre-Rueda D, Granell MV, Aldasoro M, Garcia A, Iradi A, Obrador E, Mauricio MD, Vila J, Gil-Bisquert A, Valles SL
International journal of medical sciences. 2013 Aug 3. 1278-85. FI: 2.065
[Nutrition status on pediatric admissions in Spanish hospitals; DHOSPE study].
Moreno Villares JM, Varea Calderón V, Bousoño García C, Lama Moré R, Redecillas Ferreiro S, Peña Quintana L, Sociedad Española de Gastroenterología
Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral. 2013 May-Jun. 709-18. FI: 1.305
New insights into insulin resistance, cardiovascular diseases and oxidative stress: pathophysiological and clinical consequences.
Victor VM
Current pharmaceutical design. 2013. 5661-2. FI: 3.311
Lymphocytes from Young Healthy Persons Carrying the ApoE4 Allele Overexpress Stress-Related Proteins Involved in the Pathophysiology of Alzheimer's Disease.
Badia MC, Lloret A, Giraldo E, Dasí F, Olaso G, Alonso MD, Viña J
Journal of Alzheimer's disease : JAD. 2013 Jan 1. 77-83. FI: 4.174
M2 Macrophages Activate WNT Signaling Pathway in Epithelial Cells: Relevance in Ulcerative Colitis.
Cosín-Roger J, Ortiz-Masiá D, Calatayud S, Hernández C, Alvarez A, Hinojosa J, Esplugues JV, Barrachina MD
PloS one. 2013 Oct 22. e78128. FI: 3.73
MicroRNAs miR-30b, miR-30d, and miR-494 regulate human endometrial receptivity.
Altmäe S, Martinez-Conejero JA, Esteban FJ, Ruiz-Alonso M, Stavreus-Evers A, Horcajadas JA, Salumets A
Reproductive sciences (Thousand Oaks, Calif.). 2013 Mar. 308-17. FI: 2.064
Outcome of patients with syncope beyond the implantable loop recorder.
Merlos P, Rumiz E, Ruiz-Granell R, Martínez A, Izquierdo MT, Ferrero A, Dominguez E, Sánchez JM, Morell S, García-Civera R
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2013 Jan. 122-6. FI: 2.765
Overweight, obesity, and all-cause mortality.
Viña J, Borras C, Gomez-Cabrera MC
JAMA : the journal of the American Medical Association. 2013 Apr 24. 1679. FI: 29.978
Pharmacological Properties of Physical Exercise in The Elderly.
Viña J, Borras C, Sanchis-Gomar F, Martinez-Bello VE, Olaso-Gonzalez G, Gambini J, Ingles M, Gomez-Cabrera MC
Current pharmaceutical design. 2013 Sep 27. . FI: 3.311
Potential role of physiotherapists in polymedication of the elderly.
Inglés M, Gambini J, Villaplana L
Geriatrics & gerontology international. 2013 Oct. 1086-7. FI: 2.167
Prevention of acute skeletal muscle wasting in critical illness.
Sanchis-Gomar F, Pareja-Galeano H, Cortell-Ballester J, Perez-Quilis C
Minerva anestesiologica. 2013 Nov 27. . FI: 2.818
Paraoxonase-1 Deficiency Is Associated with Severe Liver Steatosis in Mice Fed a High-fat High-cholesterol Diet: A Metabolomic Approach.
García-Heredia A, Kensicki E, Mohney RP, Rull A, Triguero I, Marsillach J, Tormos C, Mackness B, Mackness M, Shih DM, Pedro-Botet J, Joven J, Sáez G, Camps J
Journal of proteome research. 2013 Apr 5. 1946-55. FI: 5.056
Rationalizing the use of PPIs: An unresolved matter.
Ponce J, Esplugues JV
Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva. 2013 May. 121-124. FI: 1.652
[Quality of care indicators for benign prostatic hyperplasia. A qualitative study.]
Navarro-Pérez J, Peiró S, Brotons-Muntó F, López-Alcina E, Real-Romaguera A, en nombre del Grupo de trabajo del Programa de Formación e Investigación en Hiperplasia Benigna de Próstata de la Comunidad Valenciana
Atencion primaria / Sociedad Española de Medicina de Familia y Comunitaria. 2013 Dec 13. . FI: 0.957
Reductive stress in young healthy individuals at risk of Alzheimer disease.
Badía MC, Giraldo E, Dasí F, Alonso D, Lainez JM, Lloret A, Viña J
Free radical biology & medicine. 2013 Oct. 274-9. FI: 5.271
Rest heart rate and mortality: more physical exercise for the rabbit?
Lippi G, Sanchis-Gomar F, Cervellin G
International journal of cardiology. 2013 May 10. 358. FI: 5.509
Resveratrol: distribution, properties and perspectives.
Gambini J, López-Grueso R, Olaso-González G, Inglés M, Abdelazid K, El Alami M, Bonet-Costa V, Borrás C, Viña J
Revista española de geriatría y gerontología. 2013 Mar-Apr. 79-88
Sestrins: novel antioxidant and AMPK-modulating functions regulated by exercise?
Sanchis-Gomar F
Journal of cellular physiology. 2013 Aug. 1647-50. FI: 4.218
Venous thrombosis associated with HMG-CoA reductase inhibitors.
Lippi G, Favaloro EJ, Sanchis-Gomar F
Seminars in thrombosis and hemostasis. 2013 Jul. 515-32. FI: 4.216
[Effects of physical exercise on cognitive alterations and oxidative stress in an APP/PSN1 transgenic model of Alzheimer's disease].
Pareja-Galeano H, Brioche T, Sanchís-Gomar F, Escrivá C, Dromant M, Gómez-Cabrera MC, Viña J
Revista española de geriatría y gerontología. 2012 Sep. 198-204
Adrenoreceptors are involved in the stimulation of neutrophils by exercise-induced circulating concentrations of Hsp72: cAMP as a potential "intracellular danger signal".
Hinchado MD, Giraldo E, Ortega E
Journal of cellular physiology. 2012 Feb. 604-8. FI: 4.218
Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1? to exercise training.
Derbré F, Gomez-Cabrera MC, Nascimento AL, Sanchis-Gomar F, Martinez-Bello VE, Tresguerres JA, Fuentes T, Gratas-Delamarche A, Monsalve M, Viña J
Age (Dordrecht, Netherlands). 2012 Jun. 669-79. FI: 4.084
Anti-“negative-doping” testing: a new perspective in anti-doping research?
Lippi G, Sanchis-Gomar F, Banfi G
European journal of applied physiology. 2012 Jun. 2383-4. FI: 2.66
Antioxidant supplements in exercise: worse than useless?
Gomez-Cabrera MC, Ristow M, Viña J
American journal of physiology. Endocrinology and metabolism. 2012 Feb. E476-7; author reply E478-9. FI: 4.514
Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase.
Radyuk SN, Gambini J, Borras C, Serna E, Klichko VI, Viña J, Orr WC
Mechanisms of ageing and development. 2012 Jun. 401-13. FI: 3.264
Circadian System Functionality, Hippocampal Oxidative Stress, and Spatial Memory in the APPswe/PS1dE9 Transgenic Model of Alzheimer Disease: Effects of Melatonin or Ramelteon.
Otalora BB, Popovic N, Gambini J, Popovic M, Viña J, Bonet-Costa V, Reiter RJ, Camello PJ, Rol MÁ, Madrid JA
Chronobiology international. 2012 Aug. 822-34. FI: 4.35
Current limitations and future perspectives of the Athlete Blood Passport.
Lippi G, Plebani M, Sanchis-Gomar F, Banfi G
European journal of applied physiology. 2012 Oct. 3693-4. FI: 2.66
Epigenetic biomarkers: A new perspective in laboratory diagnostics.
García-Giménez JL, Sanchis-Gomar F, Lippi G, Mena S, Ivars D, Gomez-Cabrera MC, Viña J, Pallardó FV
Clinica chimica acta; international journal of clinical chemistry. 2012 Oct 9. 1576-82. FI: 2.85
Exercise acts as a drug; the pharmacological benefits of exercise.
Vina J, Sanchis-Gomar F, Martinez-Bello V, Gomez-Cabrera M
British journal of pharmacology. 2012 Sep. 41974. FI: 5.067
Front-of-Package Nutrition Labeling and Obesity Implications.
Sanchis-Gomar F, Lippi G
American journal of preventive medicine. 2012 Jan. e1. FI: 3.945
Guided implant surgery with modification of the technique involving the raising of a semicircular miniflap: a preliminary study.
Peñarrocha M, Viña J, Maestre L, Peñarrocha D, Balaguer J
Medicina oral, patología oral y cirugía bucal. 2012 Sep 1. e775-80. FI: 1.13
Hb(mass) for anti-doping purposes should be assessed in combination with hemoglobin and blood volume.
Sanchis-Gomar F, Lippi G
International journal of sports medicine. 2012 Jun. 502. FI: 2.268
Histone carbonylation occurs in proliferating cells.
García-Giménez JL, Ledesma AM, Esmoris I, Romá-Mateo C, Sanz P, Viña J, Pallardó FV
Free radical biology & medicine. 2012 Apr 15. 1453-64. FI: 5.271
Inhibition of xanthine oxidase by allopurinol prevents skeletal muscle atrophy: role of p38 MAPKinase and E3 ubiquitin ligases.
Derbre F, Ferrando B, Gomez-Cabrera MC, Sanchis-Gomar F, Martinez-Bello VE, Olaso-Gonzalez G, Diaz A, Gratas-Delamarche A, Cerda M, Viña J
PloS one. 2012. e46668. FI: 3.73
Intermittent hypobaric hypoxia applicability in myocardial infarction prevention and recovery.
Sanchis-Gomar F, Viña J, Lippi G
Journal of cellular and molecular medicine. 2012 May. 1150-4. FI: 4.753
Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes.
Sanchis-Gomar F, Lippi G, Mayero S, Perez-Quilis C, García-Giménez JL
Journal of diabetes. 2012 Sep. 196. FI: 2.939
Laboratory medicine and sports: between Scylla and Charybdis.
Lippi G, Banfi G, Botrè F, de la Torre X, De Vita F, Gomez-Cabrera MC, Maffulli N, Marchioro L, Pacifici R, Sanchis-Gomar F, Schena F, Plebani M
Clinical chemistry and laboratory medicine : CCLM / FESCC. 2012 Feb 28. 1309-16. FI: 3.009
Mitochondria as sources and targets of damage in cellular aging.
Gomez-Cabrera MC, Sanchis-Gomar F, Garcia-Valles R, Pareja-Galeano H, Gambini J, Borras C, Viña J
Clinical chemistry and laboratory medicine : CCLM / FESCC. 2012 Feb 1. 1287-95. FI: 3.009
Physical exercise as an epigenetic modulator: eustress, the "positive stress" as an effector of gene expression.
Sanchis-Gomar F, Garcia-Gimenez JL, Perez-Quilis C, Gomez-Cabrera MC, Pallardo FV, Lippi G
Journal of strength and conditioning research / National Strength & Conditioning Association. 2012 Dec. 3469-72. FI: 1.795
Plasticizer detection in urine samples after autologous blood transfusion.
Sanchis-Gomar F, Banfi G, Lippi G
Transfusion. 2012 Mar. 680; author reply 680-1. FI: 3.526
Searching for an Operational Definition of Frailty: A Delphi Method Based Consensus Statement. The Frailty Operative Definition-Consensus Conference Project.
Rodríguez-Mañas L, Féart C, Mann G, Viña J, Chatterji S, Chodzko-Zajko W, Gonzalez-Colaço Harmand M, Bergman H, Carcaillon L, Nicholson C, Scuteri A, Sinclair A, Pelaez M, Van der Cammen T, Beland F, Bickenbach J, Delamarche P, Ferrucci L, Fried LP, Gutiérrez-Robledo LM, Rockwood K, Rodríguez Artalejo F, Serviddio G, Vega E, on behalf of the FOD-CC group (Appendix 1)
The journals of gerontology. Series A, Biological sciences and medical sciences. 2012 Jan. 62-67. FI: 4.314
Survival of implants placed with the osteotome technique: an update.
Viña-Almunia J, Maestre-Ferrín L, Alegre-Domingo T, Peñarrocha-Diago M
Medicina oral, patología oral y cirugía bucal. 2012 Sep 1. e765-8. FI: 1.13
Centenarians, but not octogenarians, up-regulate the expression of microRNAs.
Serna E, Gambini J, Borras C, Mohammed K, Belenguer A, Sanchis P, Avellana JA, Rodriguez-Mañas L, Viña J
Scientific reports. 2012. 961. FI: 2.927
Telmisartan as metabolic modulator: a new perspective in sports doping?
Sanchis-Gomar F, Lippi G
Journal of strength and conditioning research / National Strength & Conditioning Association. 2012 Mar. 608-10. FI: 1.795
The financial crisis implications on the expected 2012 Olympics public health effect.
Sanchis-Gomar F, Martinez-Bello VE, Pareja-Galeano H, Lippi G
Perspectives in public health. 2012 Mar. 59
The skeletal muscle-metabolism axis in prostate-cancer therapy.
Sanchis-Gomar F
The New England journal of medicine. 2012 Dec 6. 2257-8; author reply 2258. FI: 51.658
Three weeks of erythropoietin treatment hampers skeletal muscle mitochondrial biogenesis in rats.
Martinez-Bello VE, Sanchis-Gomar F, Romagnoli M, Derbre F, Gomez-Cabrera MC, Viña J
Journal of physiology and biochemistry. 2012 Dec. 593-601. FI: 1.654
Variation of serum and urinary neutrophil gelatinase associated lipocalin (NGAL) after strenuous physical exercise.
Lippi G, Sanchis-Gomar F, Salvagno GL, Aloe R, Schena F, Guidi GC
Clinical chemistry and laboratory medicine : CCLM / FESCC. 2012 Feb 14. 1585-9. FI: 3.009
Vitamin C Supplementation Does not Improve Hypoxia-Induced Erythropoiesis.
Martinez-Bello VE, Sanchis-Gomar F, Martinez-Bello D, Olaso-Gonzalez G, Gomez-Cabrera MC, Viña J
High altitude medicine & biology. 2012 Dec. 269-74. FI: 2.122

Papel de la calcineurina y de su regulador RCAN en la respuesta cerebral al estrés oxidativo y la apoptosis: estudio en ratones RCAM-/-

Referencia:
SIN EXPEDIENTE INTRAMURAL INCLIVA VII
Investigador principal:
José Viña Ribes
Entidad financiadora:
Fundación Investigación Hospital Clínico Universitario de Valencia
Duración:
01/01/2014 - 01/01/2014
Presupuesto total:
€3.500

Applied Nanotechnologies for AGEING related clinical decisions (ANAGEING)

Referencia:
SIN EXPEDIENTE INTRAMURAL INCLIVA XVIII
Investigador principal:
José Viña Ribes
Entidad financiadora:
Fundación Investigación Hospital Clínico Universitario de Valencia
Duración:
01/01/2014 - 31/12/2014
Presupuesto total:
€4.000

Estudio de parámetros de longevidad en mujeres con tratamiento de estrógenos y progestágenos tras una menopausia inducida con GnRH

Referencia:
EXPEDIENTE 71
Investigador principal:
Consuelo Borrás Blasco
Entidad financiadora:
Fundación Investigación Hospital Clínico Universitario Valencia
Duración:
01/01/2013 - 31/12/2014
Presupuesto total:
€7.680

Según un estudio de INCLIVA la clave del envejecimiento saludable podría estar en la vía de síntesis de algunos microRNAs

Las personas con longevidad extrema viven más y experimentan un envejecimiento más saludable.

Publicado el 06/11/2017.Leer más »

Un estudio con ratones demuestra que el ejercicio físico retrasa la aparición de la fragilidad

El Grupo de Investigación en envejecimiento y ejercicio físico del INCLIVA y de la Universitat de Valencia publica un estudio con ratones que demuestra que el ejercicio físico retrasa la aparición de la fragilidad.

Publicado el 27/04/2017.Leer más »

Un año más, los investigadores de INCLIVA entre los mejores investigadores de Valencia

Según el ranking basado en el factor h elaborado por DIH, el Dr. Carlos Simón el segundo en el ranking de su especialidad en España.

Publicado el 11/01/2017.Leer más »

Un equipo de INCLIVA-UV en colaboración con el CNIO encuentra nuevas evidencias a favor del papel de la oxidación en el envejecimiento

Han generado ratones transgénicos con expresión aumentada en todo su organismo de una de las enzimas más importantes en la producción de NADPH. Los animales con niveles altos de NADPH, envejecían de forma más tardía, metabolizaban mejor el azúcar y tenían una mejor coordinación en sus movimientos al envejecer. Además, las hembras transgénicas vivían un 14% más que las no transgénicas, mientras que no observaron  efectos significativos en la longevidad de los machos.

 

Publicado el 01/04/2016.Leer más »